Association between circulating leptin levels and multiple sclerosis: a systematic review and meta-analysis.

abstract：:The side effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) on the stomach is undoubtedly a serious public health problem contributing significantly to the morbidity and mortality of patients receiving these drugs. However, the damage of NSAIDs is not confined to the stomach. Indeed the short term ...

journal_title：Postgraduate medical journal

authors： Adebayo D,Bjarnason I

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF THE STUDY:To explore which factors increase the likelihood of being deemed appointable to core anaesthesia training in the UK and whether those factors subsequently predict performance in postgraduate training. STUDY DESIGN:Observational study linking UK medical specialty recruitment data with postgraduate ...

journal_title：Postgraduate medical journal

authors： Aslet M,Paton LW,Gale T,Tiffin PA

更新日期：2020-01-01 00:00:00

abstract：:It is argued that as the major occupational cancer risks become matters of historical interest, research epidemiologists working in the field should broaden their approaches to encompass life style factors. In the investigation of possible low-cancer risks, it no longer makes any sense to confine their data-collecting...

journal_title：Postgraduate medical journal

authors： Roe FJ

更新日期：1990-05-01 00:00:00

abstract：:The clinical features of acute chlorine gas inhalation, and its management are reviewed. Current medical views on the chronic effects of an acute overwhelming exposure on lung function (reactive airways dysfunction syndrome), and the more controversial field of lung disease secondary to repeated inhalations of lower c...

journal_title：Postgraduate medical journal

authors： Williams JG

更新日期：1997-11-01 00:00:00

abstract：:The monocyte function, as measured by phagocytosis and killing of Candida albicans and Candida pseudotropicalis by peripheral blood monocytes, was found impaired in a patient with cirrhosis of the liver on two separate determinations before the occurrence of bleeding from oesophageal varices. Unexpectedly, Hodgkin's d...

journal_title：Postgraduate medical journal

authors： Dan M,Hassner A,Jedwab M,Shibolet S

更新日期：1984-07-01 00:00:00

abstract：:A case of deliberate overdose of barium sulphide in a psychiatric setting is presented, with resulting flaccid paralysis, malignant arrhythmia, respiratory arrest and severe hypokalaemia, but ultimately with complete recovery. The degree of paralysis appears to be related directly to serum barium levels. The value of ...

journal_title：Postgraduate medical journal

authors： Thomas M,Bowie D,Walker R

更新日期：1998-09-01 00:00:00

abstract：:This short overview discusses circadian rhythms observed in cardiovascular events such as myocardial ischaemia and myocardial infarction, which occur most frequently in the morning. Changes in the frequency of occurrence seem to be related to, and may result from, circadian rhythms in factors such as heart rate, blood...

journal_title：Postgraduate medical journal

authors： Fox KM,Mulcahy DA

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Large population studies now demonstrate that frailty is prevalent in all adult age groups. Limited data exist on the association between frailty and surgical outcome in younger patients. The aim of the study was to explore the agreement between frailty identification tools and collect pilot data on their predi...

journal_title：Postgraduate medical journal

authors： Dale MacLaine T,Baker O,Burke D,Howell SJ

更新日期：2021-01-12 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:A case of hyperemesis gravidarum at 9 weeks' gestation is described for which no cause could initially be found. Intravenous feeding was needed as a life preserving measure and following improvement on this regime the patient went into a thyrotoxic crisis which was successfully diagnosed and treated. The continuing pr...

journal_title：Postgraduate medical journal

authors： Valentine BH,Jones C,Tyack AJ

更新日期：1980-10-01 00:00:00

abstract：:In 17 patients with essential hypertension administration of labetalol alone resulted in a significant reduction in supine systolic and diastolic blood pressure of 14% and 17%, respectively. Seven patients attained a diastolic pressure less than equal to 95 mmHg. A significant postural fall in systolic blood pressure ...

journal_title：Postgraduate medical journal

authors： Rasmussen S,Nielsen PE

更新日期：1980-01-01 00:00:00

abstract：:Colonic strictures are very common and are a frequent finding on double contrast barium examination; they very often reflect the presence of malignancy, diverticular disease, ischaemia, inflammatory bowel disease, and rarely mycobacterial disease. A case of mycobacterial disease mimicking malignancy is presented; this...

journal_title：Postgraduate medical journal

authors： Rees JR,Longstaff A,Rigby HL,Smith DL,Dixon AR

更新日期：2003-12-01 00:00:00

abstract：:This study examines clinical features of late onset anorexia nervosa. This involved the scrutiny of a large database of patients with anorexia nervosa comprising data gathered at standardized initial assessments over the period 1960-1990. Patients with a late onset were compared to other selected patient samples. The ...

journal_title：Postgraduate medical journal

authors： Joughin NA,Crisp AH,Gowers SG,Bhat AV

更新日期：1991-11-01 00:00:00

abstract：:Two patients with severe dothiepin intoxication are described. The management of these cases is discussed and we draw attention to the prolonged elimination half-life of dothiepin and its metabolites, and the implication for treatment. ...

journal_title：Postgraduate medical journal

authors： Bloodworth L,Wilson A,Collins P,Rainford DJ

更新日期：1984-06-01 00:00:00

abstract：:The development of clinical governance in New Zealand has been pivotal to the country's health policy since 2009. Some of the key findings from one component of a national assessment project, which involved interviews with health professionals and managers at 19 of the country's 20 district health boards, are reviewed...

journal_title：Postgraduate medical journal

authors： Gauld R

更新日期：2014-01-01 00:00:00

abstract：:Colonoscopies performed in patients aged 80 years or older at the Sheba Medical Center were analysed according to the primary indication for the procedure: 101 colonoscopies were performed because of rectal bleeding of at least 2 months duration, and 335 for all other indications. Carcinoma of the large bowel was foun...

journal_title：Postgraduate medical journal

authors： Bat L,Pines A,Shemesh E,Levo Y,Zeeli D,Scapa E,Rosenblum Y

更新日期：1992-05-01 00:00:00

abstract：:A series of 8 adult patients with stable bronchial asthma and an established diagnois of essential hypertension (WHO I and II) was studied in a randomized double-blind cross-over study to assess the effect of captopril (50-100 mg/day) and verapamil (160-240 mg/day) on blood pressure, lung function and asthmatic sympto...

journal_title：Postgraduate medical journal

authors： Riska H,Stenius-Aaniala B,Sovijärvi AR

更新日期：1986-01-01 00:00:00

abstract：:Lymphocyte adenosine deaminase (L-ADA) activity, a measure of lymphocyte activity, was estimated in 10 healthy controls and 30 patients with typhoid fever (20 uncomplicated and 10 complicated) at the time of admission, at onset of complications and weekly until recovery. Mean L-ADA activity in healthy controls was 20....

journal_title：Postgraduate medical journal

authors： Khosla SN,Kumar D,Singh V

更新日期：1992-04-01 00:00:00

abstract：:Hypothyroidism over a lifetime is rare. Such a case is reported due to post-coupling dyshormonogenesis in a patient who had developed an aortic aneurysm. It is proposed that the aortic aneurysm could have arisen as a direct consequence of the hypothyroidism. Furthermore, Reilly bodies, which are deposits of mucopolysa...

journal_title：Postgraduate medical journal

authors： Savage C,Deanfield JE,Jung RT

更新日期：1982-11-01 00:00:00

abstract：:Priapism is a pathological condition of penile erection that persists beyond, or is unrelated to, sexual stimulation. Pathologically and clinically, two subtypes are seen-the high flow (non-ischaemic) variety and the low flow (ischaemic) priapism. The low flow type is more dangerous, as these patients are susceptible ...

journal_title：Postgraduate medical journal

authors： Cherian J,Rao AR,Thwaini A,Kapasi F,Shergill IS,Samman R

更新日期：2006-02-01 00:00:00

abstract：:Posterior leukoencephalopathy syndrome is a newly recognised brain disorder that predominantly affects the cerebral white matter. Oedematous lesions particularly involve the posterior parietal and occipital lobes, and may spread to basal ganglia, brain stem, and cerebellum. This rapidly evolving neurological condition...

journal_title：Postgraduate medical journal

authors： Garg RK

更新日期：2001-01-01 00:00:00

abstract：:Since January 1974, alternate cadaveric renal transplants were treated with antilymphocyte globulin (Behringwerke) om addotopm to prednisone and azathioprine. Thirty patients were treated in this way. 53% of patients receiving ALG had a functioning graft at six months as opposed to 40% in the control group. This diffe...

journal_title：Postgraduate medical journal

authors： Jakobsen J,Flatmark A,Sodal G,Thorsby E

更新日期：1976-01-01 00:00:00

abstract：:A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious dise...

journal_title：Postgraduate medical journal

authors： Fernandez-Miranda C,Mateo S,Gonzalez-Gomez C,Ballestin C

更新日期：1994-07-01 00:00:00

abstract：:I report a case of a large liver abscess causing a severe debilitating condition in which the diagnosis was delayed by several weeks following two normal ultrasound scans at days 5 and 19 of the illness. Up to one in four cases of liver abscess can be missed on ultrasound. A high degree of clinical suspicion must be m...

journal_title：Postgraduate medical journal

authors： Bunney RG

更新日期：1988-05-01 00:00:00

abstract：:The elderly, the very young, and the sick are known to be adversely affected by high environmental temperatures. In a retrospective open case-note review of 872 patients in a large institution during a hot summer we identified characteristics in the elderly that increase the risk of marginal hyperthermia. Women were m...

journal_title：Postgraduate medical journal

authors： Vassallo M,Gera KN,Allen S

更新日期：1995-04-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:This paper reports a clinical study of 20 cases of gangrenous ulcers of the scrotum and/or of the penis (Fournier's gangrene) and a review of previous publications. Even though found mostly in elderly male patients, the disease spares no age group and can involve the external genitalia in neonates and women as well. T...

journal_title：Postgraduate medical journal

authors： Efem SE

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea syndrome (OSAS) is associated with cardiovascular disease, especially in patients with high blood pressure. Continuous positive airway pressure (CPAP) seems to contribute to blood pressure control in patients with OSAS, mainly those with uncontrolled hypertension. However, the effect...

journal_title：Postgraduate medical journal

authors： de Morais Lima JH,da Cruz Santos A,Barros SE,Soares de Abreu Morais P,Figueiroa JN,Alves JG

更新日期：2016-03-01 00:00:00

abstract：:Evidence is now accumulating on both clinical and experimental grounds that the retina is an a priori source of inflammatory activity. Reactive inflammation in the retina may produce many of the clinical signs previously ascribed to uveal inflammation. Autoimmune mechanisms are probably responsible for the majority of...

journal_title：Postgraduate medical journal

authors： Sanders MD,Graham EM

更新日期：1988-07-01 00:00:00

abstract：:Toxicity to digoxin was monitored in 437 consecutive recipients in a comprehensive drug surveillance programme, Adverse reactions developed in 19.5% and, in contrast to previous reports, were generally of a relatively benign nature. There were no drug-related deaths, but patients with adverse reactions spent longer in...

journal_title：Postgraduate medical journal

authors： Henry DA,Lowe JM,Lawson DA,Whiting B

更新日期：1981-06-01 00:00:00