Is non-steroidal anti-inflammaory drug (NSAID) enteropathy clinically more important than NSAID gastropathy?

abstract：:Churg-Strauss syndrome is a systemic vasculitis. Its most frequent complications are heart diseases and asthma. Usually, cardiological manifestations are pericarditis, cardiac failure and myocardial infarction. Endobronchial granulomas identified by bronchoscopy are unusual. We present the case of a man with congestiv...

journal_title：Postgraduate medical journal

authors： Alvarez-Sala R,Prados C,Armada E,Del Arco A,Villamor J

更新日期：1995-06-01 00:00:00

abstract：:A deceased 79 year old man with a permanent cardiac pacemaker was due to be cremated, but the pacemaker generator was not detectable by palpation. A hand held metal detector to locate the device so that it could be extracted before cremation. ...

journal_title：Postgraduate medical journal

authors： Gale CP,Mulley GP

更新日期：2005-03-01 00:00:00

abstract：:Amlodipine is a dihydropyridine calcium antagonist with a unique pharmacokinetic profile providing advantages over other therapies of its kind. It has been shown to possess high oral absorption, long elimination half-life, smooth onset of action and long duration of pharmacodynamic activity. These properties result in...

journal_title：Postgraduate medical journal

authors： Taylor SH

更新日期：1991-01-01 00:00:00

abstract：:Oral administration of 1 g of acetazolamide to 8 normal subjects studied at sea level and in normoxia caused an acute increase in cerebral blood flow (CBF). During the subsequent prolonged oral treatment with 1 g of acetazolamide daily, CBF returned to normal within 2 days. The alveolar CO2 tension decreased gradually...

journal_title：Postgraduate medical journal

authors： Lassen NA,Friberg L,Kastrup J,Rizzi D,Jensen JJ

更新日期：1987-03-01 00:00:00

abstract：:We describe the occurrence of primary hyperaldosteronism in two sisters. Although this is only the second published report of familial Conn's syndrome, it does have implications for the relatives of patients with Conn's syndrome and these are discussed. ...

journal_title：Postgraduate medical journal

authors： London N,Swales J,Hollinrake K,Bell P,Heagerty A

更新日期：1992-12-01 00:00:00

abstract：:The insulin resistance/metabolic syndrome is characterised by the variable coexistence of hyperinsulinaemia, obesity, dyslipidaemia, and hypertension. The pathogenesis of the syndrome has multiple origins, but obesity and sedentary lifestyle coupled with diet and still largely unknown genetic factors clearly interact ...

journal_title：Postgraduate medical journal

authors： Kolovou GD,Anagnostopoulou KK,Cokkinos DV

更新日期：2005-06-01 00:00:00

abstract：:A case of gonococcal urethritis with bilateral tysonitis is discussed. The patient was treated successfully with oral tetracycline 500 mg 6 hourly for 10 days, with a complete resolution. ...

journal_title：Postgraduate medical journal

authors： Abdul Gaffoor PM

更新日期：1986-09-01 00:00:00

abstract：:A review of the role of presynaptic receptors in the modulation of neurotransmitter release indicates two types of presynaptic receptors. By means of presynaptic inhibitory autoreceptors a neurotransmitter can regulate its own release. In addition, presynaptic receptors are acted upon by other endogenous compounds, ei...

journal_title：Postgraduate medical journal

authors： Langer SZ,Arbilla S

更新日期：1981-01-01 00:00:00

abstract：:The clinical significance of the abnormalities seen at left ventriculography in ischaemic heart disease is discussed. Aneurysms may be recognized when left ventriculography is combined with coronary arteriography to show the characteristic obliteration of the supplying artery. Localized areas of abnormal contraction s...

journal_title：Postgraduate medical journal

authors： Khattri HN,Raphael MJ,Sharma B,Steiner RE,Goodwin JF

更新日期：1978-01-01 00:00:00

abstract：:Psychiatric symptoms are well recognized as a feature of patients with primary hyperparathyroidism. We have applied a standardized psychiatric interview to 15 patients before and after surgery. Thirteen had a lower 'psychiatric score' (less psychiatric morbidity) after surgery and improvements were particularly seen i...

journal_title：Postgraduate medical journal

authors： McAllion SJ,Paterson CR

更新日期：1989-09-01 00:00:00

abstract：:This is a study of the use of myocutaneous flaps by general surgeons in a district general hospital over a 5 year period, and shows that such work can be satisfactorily performed by general surgeons. ...

journal_title：Postgraduate medical journal

authors： Allan SM,Williams CR,Heddle RM,Jackson DB,Collins RE

更新日期：1989-10-01 00:00:00

abstract：:A case is reported where the use of i.v. disopyramide for a supraventricular tachycardia resulted in a more serious ventricular dysrhythmia giving hypotension and this probably contributed to the development of a myocardial infarction. Attention is drawn to the possible risk. ...

journal_title：Postgraduate medical journal

authors： Dibble JB,Webster NR

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Cincinnati Children's Hospital Medical Center created the Intermediate Improvement Science Series (I(2)S(2)) training course to develop organisational leaders to do improvement, lead improvement and get results on specific projects. DESIGN METHODS:Each multidisciplinary class consists of 25-30 par...

journal_title：Postgraduate medical journal

authors： Kaminski GM,Britto MT,Schoettker PJ,Farber SL,Muething S,Kotagal UR

更新日期：2013-02-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00

abstract：:In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

journal_title：Postgraduate medical journal

authors： Haiat R,Lellouch A,Lanfranchi J,Witchitz S

更新日期：1981-01-01 00:00:00

abstract：:Greater trochanteric pain syndrome (GTPS) is a commonly diagnosed regional pain syndrome with a wide spectrum of aetiologies, reflecting the anatomy of the structures outside the hip joint capsule. There are five muscle tendons that insert on to the greater trochanter and three bursae in the region of the greater troc...

journal_title：Postgraduate medical journal

authors： Chowdhury R,Naaseri S,Lee J,Rajeswaran G

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Right ventricular (RV) fractional area change and tricuspid annular plane systolic excursion (TAPSE) are recognised methods for assessing RV function. However, the way in which these variables are affected by varying degrees of pulmonary hypertension (PH) has not been well characterised. METHODS:RV end-syst...

journal_title：Postgraduate medical journal

authors： López-Candales A,Dohi K,Rajagopalan N,Edelman K,Gulyasy B,Bazaz R

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been caused the greatest pandemic of our century. Many of the deaths related to it are due to a systemic inflammatory response, which has been called 'cytokine storm'. OBJECTIVES:We developed a comprehensive review of the pathophysiology mec...

journal_title：Postgraduate medical journal

authors： Mélo Silva Júnior ML,Souza LMA,Dutra REMC,Valente RGM,Melo TS

更新日期：2020-10-02 00:00:00

abstract：:Ischaemic heart disease (IHD) related mortality has been on the decline, although its prevalence has been on the rise since the late 1970s. One of the contributing factors to this decline has been improved diagnosis and therapeutic management. Every clinician seeks to answer four key questions while evaluating patient...

journal_title：Postgraduate medical journal

authors： Raj V,Agrawal SK

更新日期：2010-09-01 00:00:00

abstract：:The selective COX-2 inhibitors (coxibs) were originally developed to minimise the adverse effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) while maintaining the same analgesic and anti-inflammatory properties. Many large studies confirmed the improved gastric side effect profile of coxibs compare...

journal_title：Postgraduate medical journal

authors： Sooriakumaran P

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF THE STUDY:There are approximately 35 000 in-hospital cardiac arrests in the UK each year. Successful resuscitation requires integration of the medical science, training and education of clinicians and implementation of best practice in the clinical setting. In 2015, the International Liaison Committee on Res...

journal_title：Postgraduate medical journal

authors： Carberry J,Couper K,Yeung J

更新日期：2017-11-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：:104 consecutive patients with upper gastrointestinal bleeding admitted to a district general hospital over a period of 20 months were considered for laser photocoagulation. 58 patients were found to have peptic ulcers, of which 42 had stigmata of recent haemorrhage accessible to laser photocoagulation. 17 were treated...

journal_title：Postgraduate medical journal

authors： Homer AC,Powell S,Vicary FR

更新日期：1985-01-01 00:00:00

abstract：:This paper reviews the current literature concerning the different investigative modalities available to assess the microcirculation in diabetic microangiopathy. The advantages and disadvantages of the different invasive and noninvasive methods available are presented objectively. We have concentrated on the tests tha...

journal_title：Postgraduate medical journal

authors： Chittenden SJ,Shami SK

更新日期：1993-06-01 00:00:00

abstract：:A 46 year old woman presented with the CREST variety of systemic sclerosis and occult gastrointestinal bleeding due to vascular malformations of her stomach. Partial gastrectomy cured her anaemia. In systemic sclerosis, visceral angiography should be performed early when initial investigations have been negative. ...

journal_title：Postgraduate medical journal

authors： el-Omar MM,Jenkins AP,Hollowood K,Banerjee AK,Thompson RP

更新日期：1994-04-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Workforce studies show a declining proportion of UK junior doctors proceeding directly to specialist training, with many taking career breaks. Doctors may be choosing to delay this important career decision. AIM:To assess doctors' views on the timing of choosing a clinical specialty. METHODS:Surveys of two...

journal_title：Postgraduate medical journal

authors： Lachish S,Goldacre MJ,Lambert TW

更新日期：2018-11-01 00:00:00

abstract：:In congestive heart failure (CHF) both the sympathetic nervous system (SNS) and the renin-angiotensin-aldosterone-system (RAAS) are activated. Both phenomena are only of short-term benefit and inevitably detrimental with prolonged activation. There are many possibilities for interaction between the systems, in particu...

journal_title：Postgraduate medical journal

authors： van Zwieten PA,de Jonge A

更新日期：1986-01-01 00:00:00

abstract：:Peyronie's disease can cause severe physical and psychological distress. Of 31 cases in this retrospective study, 12 underwent spontaneous improvement in their symptoms which makes the assessment of active treatment in other patients difficult. The indications and limitations of operative approach are discussed. ...

journal_title：Postgraduate medical journal

authors： Odiase VO,Whitaker RH

更新日期：1980-11-01 00:00:00

abstract：:A previously healthy patient developed serologically-proven Yersinia pseudotuberculosis enterocolitis and made a complete recovery. Over a year later, further gastrointestinal symptoms developed and Crohn's disease was diagnosed. The possible relevance to the aetiology of Crohn's disease is discussed. ...

journal_title：Postgraduate medical journal

authors： Treacher DF,Jewell DP

更新日期：1985-02-01 00:00:00