Myocardial infarction: a complication of amitriptyline overdose.

abstract：:A 58 year old man presented with an anterior myocardial infarction requiring repeated resuscitation. He had impaired glucose tolerance. He died five weeks later and post-mortem examination revealed a myocardial abscess and sternal osteomyelitis due to Staphylococcus aureus. These had not been apparent clinically. The ...

journal_title：Postgraduate medical journal

authors： Smith RE,Martin JE,Mills PG

更新日期：1989-08-01 00:00:00

abstract：:Staging for non-small cell lung cancer (NSCLC) requires accurate assessment of the mediastinal lymph nodes which determines treatment and outcome. As radiological staging is limited by its specificity and sensitivity, it is necessary to sample the mediastinal nodes. Traditionally, mediastinoscopy has been used for eva...

journal_title：Postgraduate medical journal

authors： Medford AR,Bennett JA,Free CM,Agrawal S

更新日期：2010-02-01 00:00:00

abstract：:Twenty-six patients with acute leukaemia and other malignancies susceptible to varicella were vaccinated with the Oka-strain live attenuated varicella vaccine during maintenance chemotherapy. All recipients showed no adverse clinical reactions. There was no spread of vaccine virus. Seroconversion was 94% in seronegati...

journal_title：Postgraduate medical journal

authors： Haas RJ,Belohradsky B,Dickerhoff R,Eichinger K,Eife R,Holtmann H,Goetz O,Graubner U,Peller P

更新日期：1985-01-01 00:00:00

abstract：:We report a 71 year old lady who presented with weight loss, rectal bleeding and bilateral foot drop having been previously fit and well. Clinical examination, laboratory investigation and postmortem examination confirmed the diagnosis of active Crohn's disease and acute peripheral neuropathy. The clinical course of t...

journal_title：Postgraduate medical journal

authors： Gariballa SE,Gunasekera NP

更新日期：1994-10-01 00:00:00

abstract：:Catheter related sepsis, especially with staphylococci, is one of the most important complications of haemodialysis or peritoneal dialysis. In a prospective, randomized, open study of 129 haemodialysis patients, exit site infection and bacteraemia were significantly greater in the untreated group (18.2% each) than the...

journal_title：Postgraduate medical journal

authors： Fong IW

更新日期：1993-01-01 00:00:00

abstract：:This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

journal_title：Postgraduate medical journal

authors： Anderson G

更新日期：1983-01-01 00:00:00

abstract：:Fistulous communications of the uterus are relatively unknown. We report in this paper the first case to our knowledge of uterocutaneous fistula which developed following a septic abortion induced by introduction of Laminaria tent into the uterus. ...

journal_title：Postgraduate medical journal

authors： Gupta SK,Shukla VK,Varma DN,Roy SK

更新日期：1993-10-01 00:00:00

abstract：:A patient with seven attacks of acute glomerulonephritis is described. Following each attack renal function returned to normal. Investigations strongly suggested immune complex disease as the cause of the nephritis but extensive tests failed to define the antigen. The possibility of an exogenous self-administered anti...

journal_title：Postgraduate medical journal

authors： Coles GA

更新日期：1983-01-01 00:00:00

abstract：:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring abo...

journal_title：Postgraduate medical journal

authors： Gazzard BG,Price H,Dawson AM

更新日期：1986-03-01 00:00:00

abstract：:" Blo -Bag", a new disposable spacer device, has been tested in conjunction with Duovent metered dose inhaler. Duovent produced a significant bronchodilatation for the duration of the study. When delivered by the " Blo -Bag" it produced a significantly greater increase in peak expiratory flow rate than when delivered ...

journal_title：Postgraduate medical journal

authors： Woodcock A,Humberstone A,Kendall J,Pierce A

更新日期：1984-01-01 00:00:00

abstract：:Two patients with nephrotic syndrome developed fatal fulminant hepatitis B following withdrawal of prednisolone or cyclophosphamide. Immunosuppressive therapy probably enhanced hepatitis B virus (HBV) replication and widespread infection of hepatocytes; its withdrawal permitted a return of immune competence resulting ...

journal_title：Postgraduate medical journal

authors： Onwubalili JK

更新日期：1988-04-01 00:00:00

abstract：:Learning curves graphically represent the relationship between learning effort and learning outcome. Learning curves are increasingly used in research, the design of randomised controlled trials, the assessment of competency, healthcare education and training programme design. In this review we have outlined the princ...

journal_title：Postgraduate medical journal

authors： Valsamis EM,Chouari T,O'Dowd-Booth C,Rogers B,Ricketts D

更新日期：2018-09-01 00:00:00

abstract：:About 0.5% of infants are infected in utero with cytomegalovirus (CMV). As many as 20% become mentally retarded and a further substantial proportion suffer lesser degrees of brain damage. The need for a vaccine is greater than in the case of rubella. A live, tissue culture-adapted strain of CMV has been shown to produ...

journal_title：Postgraduate medical journal

authors： Stern H

更新日期：1977-10-01 00:00:00

abstract：OBJECTIVE:The Pediatric Emergency Care Applied Research Network (PECARN) traumatic brain injury (TBI) age-based clinical prediction rules identify children at very low risk of a significant head injury who can safely avoid CT. Our goal was to independently validate these prediction rules. DESIGN:Cross-sectional study....

journal_title：Postgraduate medical journal

authors： Schonfeld D,Bressan S,Da Dalt L,Henien MN,Winnett JA,Nigrovic LE

更新日期：2015-11-01 00:00:00

abstract：:In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with ca...

journal_title：Postgraduate medical journal

authors： Rabinad E,Gaya J,Rivera F,Ingelmo M,Balcells A

更新日期：1986-01-01 00:00:00

abstract：:Prostate cancer is receiving ever more publicity with the result that more men are having their prostate specific antigen checked and a greater proportion of men are diagnosed with potentially curable localised disease. Advances in the therapeutic modalities including radical surgery, external beam radiotherapy, and b...

journal_title：Postgraduate medical journal

authors： Bott SR,Birtle AJ,Taylor CJ,Kirby RS

更新日期：2003-10-01 00:00:00

abstract：:Patients with coronary atherosclerosis present with angina, myocardial infarction and sudden death, most often caused by atherosclerotic stenosis complicated by spasm and/or occlusive thrombosis. All of these events have been shown to exhibit similar diurnal rhythms, with a peak incidence in the morning after waking a...

journal_title：Postgraduate medical journal

authors： Selwyn AP,Raby K,Vita JA,Ganz P,Yeung A

更新日期：1991-01-01 00:00:00

abstract：:The gastric acid response and the buffer capacity of the stomach were measured in 30 control subjects and 22 duodenal ulcer patients in response to a masticatory (solid) and a non-masticatory (homogenized) meal having the same chemical composition. The peak acid output values were equal after a masticatory and after a...

journal_title：Postgraduate medical journal

authors： Dubey P,Nundy S

更新日期：1984-04-01 00:00:00

abstract：:The majority of deaths in COPD are from cardiovascular causes. Several large randomized controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium increase the risk of serious cardiovascular events, including cardiovascular mortality. Tiotropium Respimat is associated with a statistic...

journal_title：Postgraduate medical journal

authors： Singh S,Loke YK,Enright P,Furberg CD

更新日期：2014-04-01 00:00:00

abstract：:The acute and long-term haemodynamic effects of pindolol, practolol, alprenolol, oxprenolol, acebutolol, penbutolol, metoprolol, atenolol, propranolol and timolol in patients with uncomplicated hypertension as reported in the literature were analysed. The long-term effects of these beta-adrenoceptor antagonists on pla...

journal_title：Postgraduate medical journal

authors： Man in't Veld AJ,Schalekamp MA

更新日期：1983-01-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common lab...

journal_title：Postgraduate medical journal

authors： Hui DS,Chan MC,Wu AK,Ng PC

更新日期：2004-07-01 00:00:00

abstract：:In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

journal_title：Postgraduate medical journal

authors： Scott BB,Losowsky MS

更新日期：1977-03-01 00:00:00

abstract：:A study has been made in rodents of the interactions between a range of psychotropic drugs, narcotic agonist and partial agonist analgesics, and pain. In rodents, tricyclic antidepressants do not alone reduce pain responses but, in combination with morphine or pentazocine, clomipramine enhances analgesic activity afte...

journal_title：Postgraduate medical journal

authors： Lee RL,Spencer PS

更新日期：1980-01-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread in nearly 200 countries in less than 4 months since its first identification; accordingly, the coronavirus disease 2019 (COVID 2019) has affirmed itself as a clinical challenge. The prevalence of pre-existing cardiovascular diseases in patients wi...

journal_title：Postgraduate medical journal

authors： Sisti N,Valente S,Mandoli GE,Santoro C,Sciaccaluga C,Franchi F,Cameli P,Mondillo S,Cameli M

更新日期：2020-07-30 00:00:00

abstract：:The effect of digoxin (0.25 mg t.d.s.) given orally for 5 days, on sodium excretion, plasma renin activity, plasma aldosterone and blood pressure has been studied in 6 normotensive subjects, on a constant sodium intake. Average serum digoxin level measured in 5 subjects on the 5th day of treatment was in the upper ran...

journal_title：Postgraduate medical journal

authors： Cappuccio FP,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1986-04-01 00:00:00

abstract：:We report two patients with primary adenocarcinoma of the duodenum who underwent successful pancreatico-duodenectomy (modified Whipple operation). One patient died from an unrelated cause three years following surgery whilst the other remains well and clinically free of disease 3 years after resection. An aggressive s...

journal_title：Postgraduate medical journal

authors： Carragher A,Russell C

更新日期：1987-10-01 00:00:00

abstract：:Liver transplantation is a useful treatment for end stage liver disease of all aetiologies but recurrent disease presents an ongoing challenge, particularly for hepatitis C virus (HCV) where recurrence is almost universal. Immunosuppression is needed for all patients after transplantation and should be tailored to the...

journal_title：Postgraduate medical journal

authors： Gee I,Alexander G

更新日期：2005-12-01 00:00:00

abstract：:Two cases of widespread cutaneous vasculitis are described in association with diltiazem, a recently introduced calcium antagonist. In both cases, spontaneous resolution occurred over several weeks following withdrawal of the drug. ...

journal_title：Postgraduate medical journal

authors： Sheehan-Dare RA,Goodfield MJ

更新日期：1988-06-01 00:00:00

abstract：:Psychiatric symptoms are well recognized as a feature of patients with primary hyperparathyroidism. We have applied a standardized psychiatric interview to 15 patients before and after surgery. Thirteen had a lower 'psychiatric score' (less psychiatric morbidity) after surgery and improvements were particularly seen i...

journal_title：Postgraduate medical journal

authors： McAllion SJ,Paterson CR

更新日期：1989-09-01 00:00:00

abstract：:Localized fibrous mesothelioma of the pleura is an uncommon neoplasm. Very rarely (there have been three previous cases) it may occur as an isolated mediastinal tumour. Such a tumour was present for at least 3 years in a 47 year old man, causing shortness of breath and superior vena cava syndrome. A mass weighing over...

journal_title：Postgraduate medical journal

authors： Balassiano M,Reichert N,Rosenman Y,Hertcheg E,Lieberman Y,Yellin A

更新日期：1989-10-01 00:00:00