Successful control of Cushing's disease in the elderly with long term metyrapone.

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：:Twenty-four hour intragastric acidity was measured in nine volunteer subjects in a single-blind placebo-controlled cross-over study comparing the effects of famotidine with ranitidine. The volunteer subjects received famotidine (40 mg at night), famotidine (20 mg at night), ranitidine (300 mg at night) or placebo in a...

journal_title：Postgraduate medical journal

authors： Santana IA,Lanzon-Miller S,Pounder RE

更新日期：1986-01-01 00:00:00

abstract：:The clinical features of acute chlorine gas inhalation, and its management are reviewed. Current medical views on the chronic effects of an acute overwhelming exposure on lung function (reactive airways dysfunction syndrome), and the more controversial field of lung disease secondary to repeated inhalations of lower c...

journal_title：Postgraduate medical journal

authors： Williams JG

更新日期：1997-11-01 00:00:00

abstract：:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring abo...

journal_title：Postgraduate medical journal

authors： Gazzard BG,Price H,Dawson AM

更新日期：1986-03-01 00:00:00

abstract：:Improvements in magnetic resonance (MR) imaging now permit diagnostic images of the fetus to be obtained. Ultrasound remains vital in all aspects of fetal imaging but MR provides a useful second line imaging test. Its value is best researched in fetal central nervous system disorders but it can be applied in other are...

journal_title：Postgraduate medical journal

authors： Weston MJ

更新日期：2010-01-01 00:00:00

abstract：:Helicobacter pylori is associated with gastritis, peptic ulcers and gastric malignancies. Little attention has been paid to the possibility that it may also have a role in the pathogenesis of reflux oesophagitis. This is especially true in elderly patients who have life-long infection and provide an ideal group to stu...

journal_title：Postgraduate medical journal

authors： Liston R,Pitt MA,Banerjee AK

更新日期：1996-04-01 00:00:00

abstract：:A 5-year-old girl presented with a swelling in the right axilla from which Mycobacterium avium-intracellulare was cultured. The gland was excised and she made an uneventful recovery. ...

journal_title：Postgraduate medical journal

authors： Colley EW,Cox RA

更新日期：1983-09-01 00:00:00

abstract：:A 61-year-old patient with treated Conn's syndrome due to multiple bilateral adrenocortical adenomata developed primary hyperparathyroidism. At operation, a parathyroid adenoma and a thyroid colloid nodule were found. Although adrenocortical adenomata and hyperplasia are common findings in multiple endocrine adenopath...

journal_title：Postgraduate medical journal

authors： Fertig A,Webley M,Lynn JA

更新日期：1980-01-01 00:00:00

abstract：:Peripheral lymphadenopathy is rarely observed, whereas mesenteric lymphadenopathy is found occasionally on laparotomies in patients with familial Mediterranean fever (FMF). Retroperitoneal lymphadenopathy was reported only once in an autopsy of a patient with FMF. Our case is the second one, and the first one to be di...

journal_title：Postgraduate medical journal

authors： Rimon D,Meir Y,Cohen L

更新日期：1989-10-01 00:00:00

abstract：:Coagulation problems in pregnancy are primarily associated with overactivity of the intrinsic clotting system. This accounts for the increased incidence of thrombo-embolism during pregnancy. Where specific obstetric complications cause clotting problems the common underlying feature is usually placental pathology as i...

journal_title：Postgraduate medical journal

authors： Redman CW

更新日期：1979-05-01 00:00:00

abstract：:Heart involvement by amyloid deposition remains the most challenging of all organ sytems that may become involved, in what is generally a systemic disease. The correct diagnosis of amyloid type is critical to selection of the appropriate and wide range of therapies. The treatment of amyloid heart disease comprises two...

journal_title：Postgraduate medical journal

authors： Dubrey SW

更新日期：2012-12-01 00:00:00

abstract：:A double-blind, randomized clinical trial comparing cefaclor with amoxycillin in the treatment of acute otitis media with effusion (OME) in infants and children is being conducted at Children's Hospital of Pittsburgh. Although the randomization code has not yet been broken, the results of treating the first 55 childre...

journal_title：Postgraduate medical journal

authors： Bluestone CD,Beery QC,Michaels RH,Zanotti ML,Stool SE,Grundfast KM,Wright CM,Mandel EM

更新日期：1979-01-01 00:00:00

abstract：:Exercise is known to have a vast array of health benefits. It may however confer delirious effects on most body systems, with the cardiovascular system taking particular prominence. Athletes in particular are known to be at a higher risk for sudden cardiac death as a result of several cardiac adaptations which take pl...

journal_title：Postgraduate medical journal

authors： Abela M,Sammut L

更新日期：2017-12-01 00:00:00

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：:Proper understanding of the pathological process of a ruptured plaque followed by thrombus formation remains the basis for rational therapy of cardiac ischaemia and myocardial infarction. With the advent of better thrombolytic regimens, improved direct reperfusion via angioplasty and streamlined recognition/admission ...

journal_title：Postgraduate medical journal

authors： Hugenholtz PG

更新日期：1994-01-01 00:00:00

abstract：:The Mirizzi syndrome is an unusual presentation of gallstones which occurs when a gallstone becomes impacted in either Hartmann's pouch of the gallbladder or the cystic duct, causing obstruction of the common hepatic duct by extrinsic compression. The diagnosis of this syndrome is of importance because surgery in its ...

journal_title：Postgraduate medical journal

authors： Pemberton M,Wells AD

更新日期：1997-08-01 00:00:00

abstract：:Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism--"How...

journal_title：Postgraduate medical journal

authors： McQuay HJ,Moore RA

更新日期：2005-03-01 00:00:00

abstract：:Long lists of causes of peripheral neuropathy make peripheral nerve disease a dry and uninspiring subject. A simple scheme based on the answers to just six questions should enable the clinician to recognise characteristic patterns, investigate relevant subgroups appropriately, and identify treatable disorders quickly:...

journal_title：Postgraduate medical journal

authors： Overell JR

更新日期：2012-02-01 00:00:00

abstract：:The present anti-racial discrimination legislation in the United Kingdom is embodied in the 1976 Race Relations Act. In essence this Act attempts to avoid any form of direct or indirect discrimination on the basis of racial or ethnic origin. However, health professionals are acutely aware that there are important raci...

journal_title：Postgraduate medical journal

authors： Bedi R,MacEwen M

更新日期：1990-12-01 00:00:00

abstract：:Thirty-four varicella-zoster virus (VZV) seronegative nurses were vaccinated with the live varicella vaccine (Varilrix) and followed for periods of up to 36 months. No major vaccine reactions were observed. At 5 and 12 months, 94% of the nurses had seroconverted but at 3 years, only 64% retained antibody activity. How...

journal_title：Postgraduate medical journal

authors： Ndumbe PM,Cradock-Watson JE,Heath RB,Levinsky RJ

更新日期：1985-01-01 00:00:00

abstract：:In 91 patients with bronchiectasis seen over 6 years, a positive mycobacterial culture was obtained in 12 cases (13%). The organisms isolated were Mycobacterium tuberculosis in nine cases, Mycobacterium avium in two cases and Mycobacterium tuberculosis and chelonei were obtained on separate occasions in one case. Comp...

journal_title：Postgraduate medical journal

authors： Chan CH,Ho AK,Chan RC,Cheung H,Cheng AF

更新日期：1992-11-01 00:00:00

abstract：:A patient with seven attacks of acute glomerulonephritis is described. Following each attack renal function returned to normal. Investigations strongly suggested immune complex disease as the cause of the nephritis but extensive tests failed to define the antigen. The possibility of an exogenous self-administered anti...

journal_title：Postgraduate medical journal

authors： Coles GA

更新日期：1983-01-01 00:00:00

abstract：:Serum lysozyme (muramidase) estimation is a simple, convenient and useful laboratory investigation. A review of the literature shows that lysozyme has been implicated as an aetiological factor in various disorders, and credited with being a prognostic indicator in acute myeloid leukaemia, but these promises have not b...

journal_title：Postgraduate medical journal

authors： Mir MA

更新日期：1977-05-01 00:00:00

abstract：:Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

journal_title：Postgraduate medical journal

authors： Chan NN,Isaacs AJ

更新日期：1999-02-01 00:00:00

abstract：:Pneumonia due to Mycoplasma pneumoniae is common, but it is rarely life-threatening. A case is reported in a previously healthy adult whose illness was severe enough to require treatment with intermittent positive pressure ventilation (IPPV) for 14 days and which resolved after treatment with corticosteroids. ...

journal_title：Postgraduate medical journal

authors： McGonigle R,Wagstaff JK

更新日期：1980-09-01 00:00:00

abstract：:The marked decline in coronary heart disease mortality in the United States since the late 1960s is most likely due in large part to successful efforts at primary prevention, attributable in turn to improved eating habits, better control of blood pressure and a reduction in smoking. Another part of the decline can pro...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1984-01-01 00:00:00

abstract：:Treatment of angina with a single drug often proves unsatisfactory because of dose-related unwanted effects or occasionally an adverse effect on the angina. A combination of a beta-blocking agent and a calcium antagonist drug might achieve satisfactory control of angina at acceptable doses of each drug. Widespread app...

journal_title：Postgraduate medical journal

authors： Geddes JS

更新日期：1983-01-01 00:00:00

abstract：:A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is su...

journal_title：Postgraduate medical journal

authors： Prouse PJ,Lahiri A,Gumpel JM

更新日期：1984-10-01 00:00:00

abstract：:Rectal swabs obtained from 10 of 49 chronic-care geriatric patients were positive for Clostridium difficile, for a prevalence rate of 20.4%. Simultaneous sampling of 29 patients in an acute geriatric ward revealed four colonized patients, for a prevalence rate of 13.7%. A prospective study of C. difficile colonization...

journal_title：Postgraduate medical journal

authors： Rudensky B,Rosner S,Sonnenblick M,van Dijk Y,Shapira E,Isaacsohn M

更新日期：1993-01-01 00:00:00

abstract：:A girl of 12 years old presented with acute small bowel obstruction nine weeks after an uncomplicated appendicectomy. The obstruction was found to be due to the development of sclerosing peritonitis. Previous reports of this rare condition have suggested that it is predominantly found in adolescent girls residing in s...

journal_title：Postgraduate medical journal

authors： Dehn TC,Lucas MG,Wood RF

更新日期：1985-09-01 00:00:00