Type IV renal tubular acidosis and spironolactone therapy in the elderly.

Abstract:

:Spironolactone therapy is a well-known cause of hyperkalaemia, but in susceptible patient, it may also be associated with metabolic acidosis. We report a case of severe renal tubular acidosis (Type IV) with life-threatening hyperkalaemia caused by spironolactone, and discuss the mechanisms by which this may occur.

journal_name

Postgrad Med J

authors

O'Connell JE,Colledge NR

doi

10.1136/pgmj.69.817.887

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

887-9

issue

817

eissn

0032-5473

issn

1469-0756

journal_volume

69

pub_type

杂志文章
  • Cholestyramine in the peritoneal cavity of the rat.

    abstract::The effects of cholestyramine in the peritoneal cavity of the rat are described. Cholestyramine causes mild peritonitis with adhesion formation between the liver and the omentum. In the management of biliary peritonitis, a lavage solution containing a suspension of cholestyramine would appear to be contra-indicated by...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.650.881

    authors: Walker EM

    更新日期:1979-12-01 00:00:00

  • A model for rational introduction of new and expensive medicines.

    abstract::The reported impact of human monoclonal IgM antibody (HA1A) on the mortality rate from Gram-negative bacteraemia aroused considerable interest in its use in Glasgow Royal Infirmary. However, the commercial preparation of HA1A was extremely expensive. With this in mind, the Infirmary's Drugs and Therapeutics Committee ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.71.832.86

    authors: Bell E,McCartney C

    更新日期:1995-02-01 00:00:00

  • Cefaclor compared with amoxycillin acute otitis media with effusion: a preliminary report.

    abstract::A double-blind, randomized clinical trial comparing cefaclor with amoxycillin in the treatment of acute otitis media with effusion (OME) in infants and children is being conducted at Children's Hospital of Pittsburgh. Although the randomization code has not yet been broken, the results of treating the first 55 childre...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Bluestone CD,Beery QC,Michaels RH,Zanotti ML,Stool SE,Grundfast KM,Wright CM,Mandel EM

    更新日期:1979-01-01 00:00:00

  • Transient atrial fibrillation in hypertensive patients with thiazide induced hypokalaemia.

    abstract::During the previous 34 months, 3 hypertensive patients on long-term thiazide therapy were admitted to the medical department, Mubarak Hospital, Kuwait, with atrial fibrillation (AF) and hypokalaemia. They received potassium chloride by intravenous infusion, followed by oral therapy with reversion to sinus rhythm. Ther...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.734.1125

    authors: Emara MK,Saadet AM

    更新日期:1986-12-01 00:00:00

  • An evaluation of combining thiopentone and etomidate for the induction of anaesthesia.

    abstract::The characteristics of three combinations of thiopentone and etomidate [in the ratios of thiopentone (mg):etomidate (mg) of 5:1, 13:1 and 25:1] have been compared with the individual agents alone for the induction of anaesthesia. The incidence of pain on injection and abnormal movements was less with the combination c...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/pgmj.66.777.539

    authors: Slater RM,Pollard BJ,Young TM,Hunt LP

    更新日期:1990-07-01 00:00:00

  • Subconjunctival haemorrhage: a feature of acute severe asthma.

    abstract::Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incide...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.717.579

    authors: Rodriguez-Roisin R,Torres A,Agustí AG,Ussetti P,Agustí-Vidal A

    更新日期:1985-07-01 00:00:00

  • Republished paper: assessment of doctors' consultation skills in the paediatric setting: the Paediatric Consultation Assessment Tool.

    abstract:OBJECTIVE:To determine the utility of a novel Paediatric Consultation Assessment Tool (PCAT). DESIGN:Developed to measure clinicians' communication behaviour with children and their parents/guardian, PCAT was designed according to consensus guidelines and refined at a number of stages. Volunteer clinicians provided vi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2008.146191rep

    authors: Howells RJ,Davies HA,Silverman JD,Archer JC,Mellon AF

    更新日期:2010-10-01 00:00:00

  • In vitro fertilization of hamster eggs as a test system for drug effect on spermatozoa--lack of clomipramine effect.

    abstract::Clomipramine may affect reproduction in male rats and dogs, while other psychotropic drugs can affect sperm motility in vitro. This study investigates the motility of hamster sperm and the fertilization of hamster eggs in vitro with epididymal sperm from alpha-chlorohydrin-pretreated males, and after preincubation wit...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Stein DM,Schnieden H

    更新日期:1980-01-01 00:00:00

  • Parasites in fine needle breast aspirates--assessment of host tissue response.

    abstract::Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.78.917.165

    authors: Sahai K,Kapila K,Verma K

    更新日期:2002-03-01 00:00:00

  • How, and when, can I restrain a patient?

    abstract::The need to restrain service users will vary according to the area of practice within which practitioners are employed. Many of the principles that relate to the issue of restraining service users are, however, applicable to all, or most, health and social care settings. While the emphasis should be on pre-emptive act...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.2003.007302

    authors: Horsburgh D

    更新日期:2004-01-01 00:00:00

  • Tobacco modalities used and outcome in patients with acute coronary syndrome: an observational report.

    abstract:AIM:The authors evaluated the prevalence and effect of the various tobacco use modalities among patients presenting with acute coronary syndrome (ACS) and compared them with non-tobacco and ex-tobacco users. METHODS:An analysis of the 2nd Gulf Registry of Acute Coronary Events conducted between October 2008 and June 2...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/postgradmedj-2011-130178

    authors: Al Suwaidi J,Al Habib K,Singh R,Hersi A,Al Nemer K,Asaad N,Al Saif S,Al-Motarreb A,Almahmeed W,Sulaiman K,Amin H,Al-Lawati J,Al Bustani N,Al-Sagheer NQ,Ali WM

    更新日期:2012-10-01 00:00:00

  • Primary nongestational choriocarcinoma of the ovary.

    abstract::Primary choriocarcinoma of the ovary arising, presumably, from a germ cell is extremely rare. The patient, a 16 year old girl who presented with dysuria and frequency of micturition developed fatal haemoperitoneum due to rupture of a pure primary nongestational ovarian choriocarcinoma. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.718.757

    authors: Raju GC,Woo J,Marchack D,Naraynsingh V

    更新日期:1985-08-01 00:00:00

  • The CREST syndrome--successful reduction of pulmonary hypertension by captopril.

    abstract::A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is su...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.60.708.672

    authors: Prouse PJ,Lahiri A,Gumpel JM

    更新日期:1984-10-01 00:00:00

  • Missed Addisonian crisis in surgical wards.

    abstract::Three women were admitted to the surgical wards with acute gastro-intestinal symptoms and despite good clinical (pigmentation, hypotension) and biochemical (hyponatraemia, acidosis) evidence of Addisonian crisis had unnecessary investigations with delay in the diagnosis and appropriate management of this medical emerg...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.739.367

    authors: Small M,MacCuish AC,Thomson JA

    更新日期:1987-05-01 00:00:00

  • Late presentation of a congenital gastric diverticulum causing pyloric obstruction.

    abstract::We report a case of adult pyloric obstruction caused by the delayed presentation of a congenital gastric diverticulum. The derivation, classification and treatment of these abnormalities are discussed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.68.798.296

    authors: Hale PC,O'Flynn WR

    更新日期:1992-04-01 00:00:00

  • Effect of short-term positive airway pressure on blood pressure in controlled hypertensive patients with obstructive sleep apnoea syndrome: a prospective cohort study.

    abstract:BACKGROUND:Obstructive sleep apnoea syndrome (OSAS) is associated with cardiovascular disease, especially in patients with high blood pressure. Continuous positive airway pressure (CPAP) seems to contribute to blood pressure control in patients with OSAS, mainly those with uncontrolled hypertension. However, the effect...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2014-133158

    authors: de Morais Lima JH,da Cruz Santos A,Barros SE,Soares de Abreu Morais P,Figueiroa JN,Alves JG

    更新日期:2016-03-01 00:00:00

  • What is osteoporosis?

    abstract::Osteoporosis is a very common disorder, which results in an increase in fracture risk. The annual cost attributable to hip, vertebral, and wrist fractures in England and Wales is pound 1.7 billion. Significant mortality and morbidity are associated with osteoporotic fractures. The method that is most widely used for t...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.79.929.133

    authors: Christodoulou C,Cooper C

    更新日期:2003-03-01 00:00:00

  • Strangulated femoral hernia: the persisting clinical trap.

    abstract::Five cases of strangulated femoral hernia, all with a delay in establishing the diagnosis, are reported here. These cases illustrate the continuing difficulties experienced, both in primary care and hospital practice, in making this diagnosis despite the clinical awareness of this condition. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.67.783.57

    authors: Heys SD,Brittenden J

    更新日期:1991-01-01 00:00:00

  • Yersinia colitis associated with Crohn's disease.

    abstract::A previously healthy patient developed serologically-proven Yersinia pseudotuberculosis enterocolitis and made a complete recovery. Over a year later, further gastrointestinal symptoms developed and Crohn's disease was diagnosed. The possible relevance to the aetiology of Crohn's disease is discussed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.712.173

    authors: Treacher DF,Jewell DP

    更新日期:1985-02-01 00:00:00

  • An aggressive intrasinusoidal lymphoma presenting with marked systemic disturbance but normal imaging studies.

    abstract::A patient with an aggressive intrasinusoidal non-Hodgkins lymphoma, presenting with marked systemic disturbance but only a mildly raised alkaline phosphatase as a localising sign is described. All imaging studies of the liver were normal and the diagnosis was delayed until a percutaneous liver biopsy was performed. On...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pmj.76.892.103

    authors: Camidge R,Ong E,Lucraft H

    更新日期:2000-02-01 00:00:00

  • Micronutrients in health and disease.

    abstract::Micronutrients play a central part in metabolism and in the maintenance of tissue function. An adequate intake therefore is necessary, but provision of excess supplements to people who do not need them may be harmful. Single micronutrient deficiency states are comparatively easily recognised and treated. Subclinical d...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2006.047670

    authors: Shenkin A

    更新日期:2006-09-01 00:00:00

  • Morphine: myths, morality and economics.

    abstract::It is a tragedy that morphine is scarcely available for between 1.3 and 2.5 billion people whilst 3.5 million cancer patients suffer needlessly. In only 10 countries is its consumption rising, in many more only codeine consumption shows an increase, and in many areas even in the Western world prescribing is grossly li...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Doyle D

    更新日期:1991-01-01 00:00:00

  • Aspects of fibrocystic disease of the breast. Treatment with danazol.

    abstract::The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Humphrey LJ,Estes NC

    更新日期:1979-01-01 00:00:00

  • The management of congestive heart failure.

    abstract::Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.73.858.194

    authors: McAlister FA,Teo KK

    更新日期:1997-04-01 00:00:00

  • Peyronie's disease in a district general hospital.

    abstract::Peyronie's disease can cause severe physical and psychological distress. Of 31 cases in this retrospective study, 12 underwent spontaneous improvement in their symptoms which makes the assessment of active treatment in other patients difficult. The indications and limitations of operative approach are discussed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.661.773

    authors: Odiase VO,Whitaker RH

    更新日期:1980-11-01 00:00:00

  • Surgical emphysema and pneumomediastinum in a child following minor blunt injury to the neck.

    abstract::Largyngotracheal and pharyngoesophageal tears following minor blunt trauma to the neck are uncommon. A child with such an injury is reported and the modes of diagnosis and management are discussed. Patients may initially present with minimal signs and symptoms, but their condition may deteriorate rapidly or insidiousl...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.75.887.548

    authors: Back GW,Banfield G

    更新日期:1999-09-01 00:00:00

  • Thrombotic thrombocytopenic purpura associated with pregnancy in two sisters.

    abstract::Two sisters suffered from thrombotic thrombocytopenic purpura late in their first pregnancies. HLA typing of the patients and their immediate family members demonstrated no obvious relationship. Hereditary aspects, association with pregnancy, prognosis and management of pregnant women with TTP are discussed. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.69.809.229

    authors: Alqadah F,Zebeib MA,Awidi AS

    更新日期:1993-03-01 00:00:00

  • Alcoholic liver disease.

    abstract::Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirr...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pmj.76.895.280

    authors: Walsh K,Alexander G

    更新日期:2000-05-01 00:00:00

  • Therapy of Candida peritonitis: penetration of amphotericin B into peritoneal fluid.

    abstract::Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms w...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.54.631.340

    authors: Peterson LR,Kelty RH,Hall WH,Votava HJ

    更新日期:1978-05-01 00:00:00

  • Clinical and biochemical experiences with danazol in the treatment of endometriosis in cases with female infertility.

    abstract::Based on "second look" pelviscopic control in 438 cases of pelvic endometrosis, additional hormonal antigonadotrophin therapy with danazol represents the most effective treatment for endometriosis. The rationale is well explained by Dmowski and Scommegna (1976). As endocrine treatment alone cannot control severe cases...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:

    authors: Mettler L,Semm K

    更新日期:1979-01-01 00:00:00