Therapy of Candida peritonitis: penetration of amphotericin B into peritoneal fluid.

Abstract:

:Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms were demonstrated in a gall-bladder empyema and within the gall-bladder wall. Because intra-abdominal organs may be involved in Candida peritonitis, the use of high dose amphotericin B administered either intravenously, intraperitoneally, or both intravenously and intraperitoneally is recommended.

journal_name

Postgrad Med J

authors

Peterson LR,Kelty RH,Hall WH,Votava HJ

doi

10.1136/pgmj.54.631.340

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

340-2

issue

631

eissn

0032-5473

issn

1469-0756

journal_volume

54

pub_type

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