Subcutaneous versus intravenous administration of heparin in the treatment of deep vein thrombosis; which do patients prefer? A randomized cross-over study.

Abstract:

:Patient preference for intravenous or subcutaneous heparin in the treatment of deep venous thrombosis was assessed in a randomized cross-over study. Twenty patients with venographically proven deep venous thrombosis were randomized to receive subcutaneous or intravenous heparin for 3 days followed by 3 days of the other treatment. Discomfort at the injection site, assessed by visual analogue scale, was significantly less for the subcutaneous than the intravenous administration route (P < 0.001), mobility was thought to be better when receiving subcutaneous heparin (P < 0.005) and patients' overall preference was for subcutaneous treatment (P < 0.001).

journal_name

Postgrad Med J

authors

Robinson AM,McLean KA,Greaves M,Channer KS

doi

10.1136/pgmj.69.808.115

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

115-6

issue

808

eissn

0032-5473

issn

1469-0756

journal_volume

69

pub_type

临床试验,杂志文章,随机对照试验
  • Finger clubbing and aspartylglucosamine excretion in a laxative-abusing patient.

    abstract::A young woman with a previous history of anorexia nervosa presented with severe finger clubbing. Urine samples intermittently contained significant amounts of aspartylglucosamine. Liver biopsy showed abnormal cytoplasmic inclusions in phagocytic cells. The patient was found to be abusing senna laxative. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.662.862

    authors: Malmquist J,Ericsson B,Hultén-Nosslin MB,Jeppsson JO,Ljungberg O

    更新日期:1980-12-01 00:00:00

  • COX-2 inhibitors and the heart: are all coxibs the same?

    abstract::The selective COX-2 inhibitors (coxibs) were originally developed to minimise the adverse effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) while maintaining the same analgesic and anti-inflammatory properties. Many large studies confirmed the improved gastric side effect profile of coxibs compare...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2005.042234

    authors: Sooriakumaran P

    更新日期:2006-04-01 00:00:00

  • The antemortem diagnosis of pyogenic liver abscess due to perforation of the gut by a foreign body.

    abstract::Perforation of the gastrointestinal tract by ingested foreign bodies is rare; the diagnosis of pyogenic liver abscess resulting from such perforations is usually made at post-mortem. We present a case of perforation of the gut, due to an ingested dental plate, with a resultant pyogenic liver abscess, which presented a...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.59.693.455

    authors: Shaw PJ,Freeman JG

    更新日期:1983-07-01 00:00:00

  • Optimising clinical performance during resuscitation using video evaluation.

    abstract::Video evaluation of resuscitation is becoming increasingly integrated into practice in a number of clinical settings. The purpose of this review article is to examine how video may enhance clinical care during resuscitation. As healthcare and available therapeutic interventions evolve, re-evaluation of accepted paradi...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/postgradmedj-2016-134357

    authors: Lowe DJ,Dewar A,Lloyd A,Edgar S,Clegg GR

    更新日期:2017-08-01 00:00:00

  • Bone disease after jejuno-ileal bypass for morbid obesity.

    abstract::Fifteen patients who had undergone a 14 inches X 4 inches jejuno-ileal bypass operation for obesity, 3 to 4 years earlier, were investigated by iliac bone biopsy, radiology and routine biochemistry, including 25-hydroxy-vitamin D and parathyroid hormone estimations. Two patients had histological osteomalacia which was...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.59.691.299

    authors: Gilmore IT,Eastwood JB,Ellis WR,Luck VA,Fenton S,O'Grady AJ,Harris E,Murray-Lyon IM

    更新日期:1983-05-01 00:00:00

  • National review of urology outpatient practice in the UK.

    abstract:OBJECTIVE:To audit the current UK outpatient workload and compare this to the national standards as set out by the British Association of Urological Surgeons (BAUS) in A Quality Urological Service for Patients in the New Millennium published in October 2000. PARTICIPANTS:520 UK (NHS) and 21 Republic of Ireland (non-NH...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/pgmj.2004.020693

    authors: Gilmore PE,Shackley DC,Clarke NW,Betts CD,O'Flynn KJ

    更新日期:2005-01-01 00:00:00

  • A comparison of the haemodynamic effects of propofol ('Diprivan') and thiopentone in patients with coronary artery disease.

    abstract::Twenty patients scheduled for elective coronary surgery received either propofol ('Diprivan') 1.5 mg/kg in emulsion or thiopentone 2 mg/kg for induction of anaesthesia. Vecuronium was used for neuromuscular blockade. Cardiovascular dynamics were recorded every minute until 6 min after intubation. Anaesthesia with prop...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Patrick MR,Blair IJ,Feneck RO,Sebel PS

    更新日期:1985-01-01 00:00:00

  • Perceptions of medical school graduates and students regarding their academic preparation to teach.

    abstract:PURPOSE:How medical students learn and develop the characteristics associated with good teaching in medicine is not well known. Information about this process can improve the academic preparation of medical students for teaching responsibilities. The purpose of this study was to determine how different experiences cont...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2006.045393

    authors: Henry BW,Haworth JG,Hering P

    更新日期:2006-09-01 00:00:00

  • Localized fibrous mesothelioma of the mediastinum devoid of pleural connections.

    abstract::Localized fibrous mesothelioma of the pleura is an uncommon neoplasm. Very rarely (there have been three previous cases) it may occur as an isolated mediastinal tumour. Such a tumour was present for at least 3 years in a 47 year old man, causing shortness of breath and superior vena cava syndrome. A mass weighing over...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.768.788

    authors: Balassiano M,Reichert N,Rosenman Y,Hertcheg E,Lieberman Y,Yellin A

    更新日期:1989-10-01 00:00:00

  • Coeliac disease with mild mucosal abnormalities: a report of four patients.

    abstract::In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.53.617.134

    authors: Scott BB,Losowsky MS

    更新日期:1977-03-01 00:00:00

  • Endobronchial ultrasound guided transbronchial needle aspiration.

    abstract::Staging for non-small cell lung cancer (NSCLC) requires accurate assessment of the mediastinal lymph nodes which determines treatment and outcome. As radiological staging is limited by its specificity and sensitivity, it is necessary to sample the mediastinal nodes. Traditionally, mediastinoscopy has been used for eva...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2009.089391

    authors: Medford AR,Bennett JA,Free CM,Agrawal S

    更新日期:2010-02-01 00:00:00

  • Successful control of Cushing's disease in the elderly with long term metyrapone.

    abstract::A 77-year old woman with pituitary-driven Cushing's disease is described. The condition was completely controlled on long-term treatment with metyrapone. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.730.727

    authors: Donckier J,Burrin JM,Ramsay ID,Joplin GF

    更新日期:1986-08-01 00:00:00

  • Orthostatic haemodynamic responses in acute stroke.

    abstract::Little is known about orthostatic blood pressure regulation in acute stroke. We determined postural haemodynamic responses in 40 patients with acute stroke (mild or moderate severity) and 40 non-stroke control in-patients, at two days ('Day 1') and one week ('Week 1') post-admission. Following a 10-minute supine rest ...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章

    doi:10.1136/pgmj.75.882.213

    authors: Panayiotou B,Reid J,Fotherby M,Crome P

    更新日期:1999-04-01 00:00:00

  • Radiation effects on the intima-media thickness of the common carotid artery in post-radiotherapy patients with head and neck malignancy.

    abstract:BACKGROUND:Post-radiation large vessel injury has not received as much attention as microvascular irradiation injury. A few studies have shown that common carotid intima-media thickness (IMT) is increased after radiotherapy to the head and neck. However, in most of these studies, the irradiated subjects also had other ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2008.068569

    authors: Shariat M,Alias NA,Biswal BM

    更新日期:2008-11-01 00:00:00

  • Timing of intervention in acute pancreatitis.

    abstract::This review examines the appropriate timing of intervention in acute pancreatitis. In gallstone pancreatitis, it is now clear that cholecystectomy during the primary admission carries no greater risk of complications than delayed cholecystectomy and enables earlier recovery to normal activity. This course of action pr...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.69.813.509

    authors: Johnson CD

    更新日期:1993-07-01 00:00:00

  • Lack of response to octreotide in Cushing's syndrome due to metastatic adrenocortical carcinoma.

    abstract::Functional metastatic adrenocortical carcinoma is an uncommon cause of Cushing's syndrome, which rarely responds to conventional treatment. A patient presenting with Cushing's syndrome secondary to adrenocortical carcinoma underwent surgical resection. Postoperatively, she developed metastatic disease resistant to con...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.75.880.96

    authors: Chan NN,Isaacs AJ

    更新日期:1999-02-01 00:00:00

  • Anticholinergic drugs in airways obstruction.

    abstract::This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Anderson G

    更新日期:1983-01-01 00:00:00

  • Pubic osteomyelitis presenting as irritable hip.

    abstract::Two cases of pubic osteomyelitis presenting as a painful hip are reported. In both cases the diagnosis was delayed by the unusual presentation and by the limited radiological investigation. Pubic osteomyelitis is rare in childhood but should be considered in the differential diagnosis of the 'irritable hip'. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.738.301

    authors: Weinberg JR,Berman L,Dootson G,Mitchell R

    更新日期:1987-04-01 00:00:00

  • Ulcerative colitis and sarcoidosis.

    abstract::Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.727.341

    authors: Barr GD,Shale DJ,Jewell DP

    更新日期:1986-05-01 00:00:00

  • Hypogammaglobulinaemia associated with long term, low dose steroid therapy.

    abstract::Repeated pneumonia and hypogammaglobulinaemia was associated with long term low dose steroid therapy. Clinical improvement with restoration of antibody levels followed substitution of aerosol for oral therapy. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.716.523

    authors: Lee RJ,Fay AC

    更新日期:1985-06-01 00:00:00

  • Measurement of the effects of a single dose of prazosin on the cerebral blood flow in hypertensive patients.

    abstract::It was considered that the first dose reaction occurring with prazosin may have been due either to hypotension or to a specific reduction in cerebral blood flow. The development of a quantitative non-invasion nuclear medicine technique for cerebral flow has now made it possible to investigate the effects of prazosin o...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/pgmj.56.662.818

    authors: Rutland MD,Lee TY,Nimmon CC,Granowska M,Britton KE

    更新日期:1980-12-01 00:00:00

  • Effect of insulin in the induction and regression of experimental cholesterol atherosclerosis in the rabbit.

    abstract::A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-chol...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.54.628.80

    authors: Marquié G

    更新日期:1978-02-01 00:00:00

  • Demeclocycline therapy for resistant oedema in advanced cardiac failure.

    abstract::A patient with long-standing ischaemic heart disease and severe low output congestive cardiac failure received numerous diuretics, which gradually became ineffective. Resistant oedema was treated by adding demeclocycline to the current diuretic regime of frusemide and metolazone. Diuresis resulted, oedema disappeared ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.652.121

    authors: Bonser RS,Ghose RR

    更新日期:1980-02-01 00:00:00

  • Bacterial calcification in infective endocarditis.

    abstract::The present report is the first description to our knowledge of a clinical case of bacterial calcification in human infective endocarditic vegetations. Partial calcification of bacteria within vegetations may be a further mechanism of bacterial protection from host defences and antibiotics. Similar calcification has r...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.767.665

    authors: Poller DN,Curry A,Ganguli LA,Routledge RC

    更新日期:1989-09-01 00:00:00

  • Periodic paralysis complicating malaria.

    abstract::Episodic muscular weakness, commonly associated with alterations of serum potassium, is the cardinal feature of periodic paralysis. The combination of transient hyperkalaemia and rigors occurring during febrile episodes of malaria is suggested as the underlying cause which precipitated the muscular paralysis. Three pa...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.57.667.273

    authors: Senanayake N,Wimalawansa SJ

    更新日期:1981-05-01 00:00:00

  • Heparin-associated skin necrosis.

    abstract::A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not uncommon. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.66.777.573

    authors: Fowlie J,Stanton PD,Anderson JR

    更新日期:1990-07-01 00:00:00

  • Observation and identification of lactate dehydrogenase anomaly in a postburn patient.

    abstract:OBJECTIVE:Lactate dehydrogenase (LDH) anomaly is one of the macroenzymes. Macroenzymes are enzymes in serum that have formed high molecular mass complexes, either by self polymerisation or by association with other serum components. The aim of this study was to identify the properties of LDH anomaly and observe the cha...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.2003.015420

    authors: Liu ZJ,Zhang Y,Zhang XB,Yang X

    更新日期:2004-08-01 00:00:00

  • Use of diuretics in cardiovascular diseases: (1) heart failure.

    abstract::Diuretics are used extensively in hospitals and in community medical practice for the management of cardiovascular diseases. They are used frequently as the first line treatment for mild to moderate hypertension and are an integral part of the management of symptomatic heart failure. Although diuretics have been used ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2003.010835

    authors: Shah SU,Anjum S,Littler WA

    更新日期:2004-04-01 00:00:00

  • Hepatic metastases due to choriocarcinoma.

    abstract::A 34 year old female presented with weight loss and hepatomegaly. Liver biopsy revealed clinically unsuspected metastatic choriocarcinoma. Severe haemorrhage occurred, and the patient died following complications after laparotomy. The possibility of choriocarcinoma should be remembered in women of child-bearing age wh...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.758.941

    authors: Alveyn CG,Loehry CA

    更新日期:1988-12-01 00:00:00

  • Primary hepatocellular carcinoma associated with Wilson's disease in a young woman.

    abstract::A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout t...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.714.357

    authors: Guan R,Oon CJ,Wong PK,Foong WC,Wee A

    更新日期:1985-04-01 00:00:00