Finger clubbing and aspartylglucosamine excretion in a laxative-abusing patient.

abstract：:A case of cerebral embolism is described in which paradoxical features have been proved clinically, and which may explain some hitherto unaccountable reported cases, and suggests the value of prospective studies. A successful outcome of such a proved case, associated with oral contraceptives, does not appear to have b...

journal_title：Postgraduate medical journal

authors： de Swiet J

更新日期：1979-06-01 00:00:00

abstract：:A 24 year old woman living in the Mediterranean region of Turkey present with a three-month history of weight loss and irregular fever that was peaking at 40 degrees C with shivering. No definite aetiology could be identified in a local hospital. A bacterial infection had been suspected, but antibiotic therapy, at fir...

journal_title：Postgraduate medical journal

authors： Büyükaşik Y,Ileri NS,Haznedaroğlu IC,Demiroğlu H,Dündar S

更新日期：1998-04-01 00:00:00

abstract：:We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide. We describe a possible drug interaction between these two drugs and recommend that they should only be used together with c...

journal_title：Postgraduate medical journal

authors： Webberley MJ,Murray JA

更新日期：1989-12-01 00:00:00

abstract：:Amlodipine is a dihydropyridine calcium antagonist with a unique pharmacokinetic profile providing advantages over other therapies of its kind. It has been shown to possess high oral absorption, long elimination half-life, smooth onset of action and long duration of pharmacodynamic activity. These properties result in...

journal_title：Postgraduate medical journal

authors： Taylor SH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Workforce studies show a declining proportion of UK junior doctors proceeding directly to specialist training, with many taking career breaks. Doctors may be choosing to delay this important career decision. AIM:To assess doctors' views on the timing of choosing a clinical specialty. METHODS:Surveys of two...

journal_title：Postgraduate medical journal

authors： Lachish S,Goldacre MJ,Lambert TW

更新日期：2018-11-01 00:00:00

abstract：:We describe two cases of digoxin toxicity presenting with clinical and electroencephalographic evidence of encephalopathy without other features of digoxin toxicity. ...

journal_title：Postgraduate medical journal

authors： Greenaway JR,Abuaisha B,Bramble MG

更新日期：1996-06-01 00:00:00

abstract：:Localized fibrous mesothelioma of the pleura is an uncommon neoplasm. Very rarely (there have been three previous cases) it may occur as an isolated mediastinal tumour. Such a tumour was present for at least 3 years in a 47 year old man, causing shortness of breath and superior vena cava syndrome. A mass weighing over...

journal_title：Postgraduate medical journal

authors： Balassiano M,Reichert N,Rosenman Y,Hertcheg E,Lieberman Y,Yellin A

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:To analyse the clinicopathological presentation, outcome and importance of bone marrow haemophagocytosis in patients with infection-associated haemophagocytic lymphohistiocytosis (IA-HLH) in a tertiary care hospital in Northern India. STUDY DESIGN:Between January 2007 and December 2009, 26 consecutive patien...

journal_title：Postgraduate medical journal

authors： Nair V,Das S,Sharma A,Sharma S,Sharma P,Ray S,Bhattacharya S

更新日期：2013-04-01 00:00:00

abstract：:Sir William Osler organized a journal club at McGill University in 1875, and several authors suggest that journal clubs were found in certain European countries (in particular, Germany and England) prior to that time. The evolution and development of the journal club, however, has not been recorded in the medical lite...

journal_title：Postgraduate medical journal

authors： Linzer M

更新日期：1987-06-01 00:00:00

abstract：:The factors related to the occurrence of bacteraemia following urinary tract manipulation were studied in a large community hospital. During a 3-year period, forty-six of 326 episodes of hospital-acquired bacteraemia were associated with urinary tract manipulation. All thirty of forty-six cases felt to be definitely r...

journal_title：Postgraduate medical journal

authors： Quintiliani R,Klimek J,Cunha BA,Maderazo EG

更新日期：1978-10-01 00:00:00

abstract：:Acute retinal necrosis (ARN), also known as Kirisawa-type uveitis, is an uncommon condition caused by infection of the retina by one of the herpes family of viruses, most typically varicella zoster virus or herpes simplex virus and less commonly cytomegalovirus. Clinical diagnosis can be challenging and is often aided...

journal_title：Postgraduate medical journal

authors： Wong RW,Jumper JM,McDonald HR,Johnson RN,Fu A,Lujan BJ,Cunningham ET Jr

更新日期：2013-08-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:To determine the prevalence and extent of autonomic neuropathy amongst Africans with insulin-dependent diabetes mellitus (IDDM), we investigated 50 such patients at our clinic. Mean age (+/- 1 s.d.) was 26 +/- 6 years, male:female ratio was equal (25M:25F) and duration of diabetes was 4.0 +/- 3.0 years. A battery of s...

journal_title：Postgraduate medical journal

authors： Tuch PS,Gill GV,Huddle KR

更新日期：1994-03-01 00:00:00

abstract：:Stroke is the third most common cause of death in developed countries. In England and Wales, 1000 people under the age of 30 have a stroke each year. Cocaine is the most commonly used class A drug, and the first report of cocaine-induced stroke was in 1977. Since the development of alkaloidal "crack" cocaine in the 19...

journal_title：Postgraduate medical journal

authors： Treadwell SD,Robinson TG

更新日期：2007-06-01 00:00:00

abstract：:Haemorrhagic infarction of the breast induced by anticoagulant therapy is rare and has been infrequently reported in the literature. The following report illustrates such a case in which there was development of massive haemorrhagic infarction of the breast during treatment with nicoumalone for deep venous thrombosis ...

journal_title：Postgraduate medical journal

authors： Banik S,Brun C

更新日期：1982-01-01 00:00:00

abstract：:A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is su...

journal_title：Postgraduate medical journal

authors： Prouse PJ,Lahiri A,Gumpel JM

更新日期：1984-10-01 00:00:00

abstract：:Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

journal_title：Postgraduate medical journal

authors： McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

更新日期：1979-09-01 00:00:00

abstract：:Retroperitoneal fibrosis, either idiopathic or associated with aortic inflammatory aneurysm, is a chronic fibrotic disease that causes progressive obstruction of ureters and vessels around the lower abdominal aorta. Treatment is often difficult (surgery) or hazardous (steroids). We report a case of a woman with retrop...

journal_title：Postgraduate medical journal

authors： Frankart L,Lorge F,Donckier J

更新日期：1997-10-01 00:00:00

abstract：:The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. Th...

journal_title：Postgraduate medical journal

authors： Gillett AP,Andrews JM,Wise R

更新日期：1979-01-01 00:00:00

abstract：:Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

journal_title：Postgraduate medical journal

authors： Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

更新日期：1988-01-01 00:00:00

abstract：:I report a case of a large liver abscess causing a severe debilitating condition in which the diagnosis was delayed by several weeks following two normal ultrasound scans at days 5 and 19 of the illness. Up to one in four cases of liver abscess can be missed on ultrasound. A high degree of clinical suspicion must be m...

journal_title：Postgraduate medical journal

authors： Bunney RG

更新日期：1988-05-01 00:00:00

abstract：:The recognition and treatment of depression is a challenging area of clinical practice, especially in primary care where there are many patients with various presentations and a multitude of causes for distress. The prevalence of depression is increasing, and it is predicted to become second only to ischaemic heart di...

journal_title：Postgraduate medical journal

authors： Lester H,Howe A

更新日期：2008-10-01 00:00:00

abstract：:Renal disease in Churg-Strauss syndrome is generally thought to be benign in nature, thereby distinguishing this rare condition from other necrotizing vasculitides. We report a case in which acute renal failure developed during the aggressive vasculitic phase of the illness requiring dialysis therapy. After one week o...

journal_title：Postgraduate medical journal

authors： Davenport A,McDicken I,Goldsmith HJ

更新日期：1988-09-01 00:00:00

abstract：:The most sensitive index of hepatic encephalopathy in 29 patients following a porta-caval shunt appeared to be the assessment of a close relative who had known the patient pre-operatively. They noticed that 19 of the 20 patients were mentally slower; 11 were markedly aggressive and 8 had become placid and uncaring abo...

journal_title：Postgraduate medical journal

authors： Gazzard BG,Price H,Dawson AM

更新日期：1986-03-01 00:00:00

abstract：:A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parot...

journal_title：Postgraduate medical journal

authors： Steuer A,McCrea DJ,Colaco CB

更新日期：1996-08-01 00:00:00

abstract：:Very few cases of acquired severe copper deficiency have been described. The principal effects are haematological, but the precise abnormalities are uncertain due to the possible association of other deficiencies. A case of isolated severe copper deficiency associated with late onset hypogammaglobulinaemia is reported...

journal_title：Postgraduate medical journal

authors： Oppenheimer SM,Hoffbrand BI,Dormandy TL,Parker N,Wickens DG

更新日期：1987-03-01 00:00:00

abstract：:Hypersensitivity reactions to chemotherapy drugs pose significant difficulties in management, especially when no suitable alternative is available or acceptable and delay in continuation of treatment may be life-threatening. Such reactions may be IgE- or non-IgE-mediated and have varied manifestations. Timely recognit...

journal_title：Postgraduate medical journal

authors： Tham EH,Cheng YK,Tay MH,Alcasabas AP,Shek LP

更新日期：2015-03-01 00:00:00

abstract：:We describe the occurrence of primary hyperaldosteronism in two sisters. Although this is only the second published report of familial Conn's syndrome, it does have implications for the relatives of patients with Conn's syndrome and these are discussed. ...

journal_title：Postgraduate medical journal

authors： London N,Swales J,Hollinrake K,Bell P,Heagerty A

更新日期：1992-12-01 00:00:00

abstract：:Ultrasound guidance has been reported to facilitate the performance of lumbar punctures (LPs). However, the use of ultrasound guidance has not yet received consistent conclusions. We performed a systematic review and meta-analysis to determine the efficacy of ultrasound-guided LPs. PubMed, Embase and the Cochrane Libr...

journal_title：Postgraduate medical journal

authors： Shu L,Huang J,Liu JC

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Physicians can come across patients who are exposed to certain prescription drugs or toxins that can result in adverse effects and complications which have high rates of morbidity and mortality. OBJECTIVE:To summarise the key clinical features and management of the common movement disorder toxidromes releva...

journal_title：Postgraduate medical journal

authors： Malek N,Baker MR

更新日期：2017-06-01 00:00:00