How, and when, can I restrain a patient?

abstract：:Twelve healthy volunteers took part in a randomised, double-blind, balanced, cross-over study to investigate the effect of misoprostol on the pharmacokinetics of propranolol. The subjects took propranolol 80 mg twice daily by mouth plus either misoprostol 400 micrograms twice daily or placebo by mouth for 14.5 days, f...

journal_title：Postgraduate medical journal

authors： Bennett PN,Fenn GC,Notarianni LJ,Lee CE

更新日期：1991-05-01 00:00:00

abstract：:Haemorrhage of small bowel origin may prove to be a clinical and diagnostic challenge, particularly when the bleeding is massive and continuous. Such a case is described where the source of blood loss was a jejunal vascular abnormality. ...

journal_title：Postgraduate medical journal

authors： Saunders MP

更新日期：1991-07-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:Strips form canine saphenous veins were incubated with (3H)-noradrenaline and mounted for superfusion. 5-Hydroxytryptamine (5-HT inhibited the release of tritium caused by sustained electrical stimulation (2 Hz, 150 mA, 0.1 msec) being about 10 times more potent than noradrenaline. 5-HT inhibited contractions induced ...

journal_title：Postgraduate medical journal

authors： Müller-Schweinitzer E

更新日期：1981-01-01 00:00:00

abstract：:Disc herniation at the thoracic the spine level is more common than generally thought. Localisation of pain may be vague and may erroneously point to cardiopulmonary, gastrointestinal, genito-urinary or even psychiatric disease. Magnetic resonance imaging is the investigation of choice, especially if spinal cord compr...

journal_title：Postgraduate medical journal

authors： Pal B,Johnson A

更新日期：1997-07-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:Recurrence of adrenal cortical carcinoma 22 years after first presentation is reported in a 54-year-old woman with Cushing's syndrome. This tumour is normally associated with poor prognosis and prolonged survival is rare. Although the patient had remained well with apparent 'cure' in the intervening years, it is sugge...

journal_title：Postgraduate medical journal

authors： Shaw KM,Fisher C,Peters JL,Ross EJ

更新日期：1979-10-01 00:00:00

abstract：OBJECTIVE:To assess parent preferences for utilisation of a parent-focused, telephone-based coaching service, or 'FITLINE,' to prevent or manage childhood obesity. METHODS:A cross-sectional survey of parents of children aged 2-12 years was conducted at a paediatric practice in Greater Boston, Massachusetts, USA, betwe...

journal_title：Postgraduate medical journal

authors： Blaine RE,Pbert L,Geller AC,Powers EM,Mitchell K

更新日期：2015-04-01 00:00:00

abstract：:The effective training of facilitator/ tutors is crucial to the success of a problem-based learning approach to medical education. New skills are needed to accomplish the change from giver of information to facilitator of learning, coach, and guide. This paper outlines considerations for the design of a tutor training...

journal_title：Postgraduate medical journal

authors： Wetzel MS

更新日期：1996-08-01 00:00:00

abstract：:The reported impact of human monoclonal IgM antibody (HA1A) on the mortality rate from Gram-negative bacteraemia aroused considerable interest in its use in Glasgow Royal Infirmary. However, the commercial preparation of HA1A was extremely expensive. With this in mind, the Infirmary's Drugs and Therapeutics Committee ...

journal_title：Postgraduate medical journal

authors： Bell E,McCartney C

更新日期：1995-02-01 00:00:00

abstract：:With the introduction of the New Deal and the Calman Report, the duration of higher specialist training will be halved. We have examined the effect of reduced on-call rotas on exposure to relatively uncommon out-of-hours emergencies in cardiothoracic surgery. Operations for post-infarction ventricular septal defect, a...

journal_title：Postgraduate medical journal

authors： Kelty C,Duffy J,Cooper G

更新日期：1999-06-01 00:00:00

abstract：:Stroke is the third most common cause of death in developed countries. In England and Wales, 1000 people under the age of 30 have a stroke each year. Cocaine is the most commonly used class A drug, and the first report of cocaine-induced stroke was in 1977. Since the development of alkaloidal "crack" cocaine in the 19...

journal_title：Postgraduate medical journal

authors： Treadwell SD,Robinson TG

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Asthma, a common childhood condition, often presents with chronic cough. While evaluating for chronic cough, many specialists obtain a baseline chest radiograph (CR) to assess for other causes. Usually read as 'normal', sometimes CRs will reveal evidence of airway inflammation in the form of subtle findings,...

journal_title：Postgraduate medical journal

authors： Abeles M,Akerman M,Halaby C,Pirzada M

更新日期：2020-12-03 00:00:00

abstract：:Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour. We describe, and illustrate, a patient presenting with features related to cardiac tamponade and intracardiac obstruction. Transthoracic echocardiography initially showed a large mass wit...

journal_title：Postgraduate medical journal

authors： Dubrey S,Grocott-Mason R,Mittal T,Burke M

更新日期：2008-03-01 00:00:00

abstract：:During one year, out of 1829 faecal specimens examined at the Chelmsford Public Health Laboratory, campylobacters were isolated from 109 (6%), 21 of the positive cultures were from hospital in-patients and 3 were from hospital staff. The remaining 85 isolates were from specimens sent in by general practitioners. The a...

journal_title：Postgraduate medical journal

authors： Bradshaw MJ,Brown R,Swallow JH,Rycroft JA

更新日期：1980-02-01 00:00:00

abstract：:Improvements in magnetic resonance (MR) imaging now permit diagnostic images of the fetus to be obtained. Ultrasound remains vital in all aspects of fetal imaging but MR provides a useful second line imaging test. Its value is best researched in fetal central nervous system disorders but it can be applied in other are...

journal_title：Postgraduate medical journal

authors： Weston MJ

更新日期：2010-01-01 00:00:00

abstract：:Amlodipine is a dihydropyridine calcium antagonist with a unique pharmacokinetic profile providing advantages over other therapies of its kind. It has been shown to possess high oral absorption, long elimination half-life, smooth onset of action and long duration of pharmacodynamic activity. These properties result in...

journal_title：Postgraduate medical journal

authors： Taylor SH

更新日期：1991-01-01 00:00:00

abstract：:Five cases of primary peritonitis are presented, with a sixth related case of pneumococcal peritonitis secondary to a ruptured ovarian cyst. The patients comprised 4 young girls who recovered, and 2 elderly females who died. Pneumococci were isolated in 3 patients; no organism was found in the other 3. One case of pri...

journal_title：Postgraduate medical journal

authors： Armitage TG,Williamson RC

更新日期：1983-01-01 00:00:00

abstract：:The clinical features of acute chlorine gas inhalation, and its management are reviewed. Current medical views on the chronic effects of an acute overwhelming exposure on lung function (reactive airways dysfunction syndrome), and the more controversial field of lung disease secondary to repeated inhalations of lower c...

journal_title：Postgraduate medical journal

authors： Williams JG

更新日期：1997-11-01 00:00:00

abstract：:Two female patients who suffered from drug-induced thrombocytopenic purpura and subendocardial myocardial infarction are presented. One of them died from cerebral haemorrhage and diffuse subendocardial punctate haemorrhages were found at post-mortem. The abnormal haemostasis which is associated with thrombocytopenia m...

journal_title：Postgraduate medical journal

authors： Fireman Z,Yust I,Zahavi J,Kahn Y,Abramov LA

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:The British Thoracic Society (BTS) guidelines have not been examined collectively for their impact on chronic obstructive pulmonary disease (COPD). Whether intensive outpatient follow up of COPD patients after acute admission, using these guidelines, improved quality of life compared to the "usual practice" ...

journal_title：Postgraduate medical journal

authors： Dheda K,Crawford A,Hagan G,Roberts CM

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:To determine the association between professors' self-perception of mentoring skills and their academic performance. DESIGN:Two hundred and fifteen professors from Imperial College London, the first Academic Health Science Centre (AHSC) in the UK, were surveyed. The instrument adopted was the Mentorship Skills...

journal_title：Postgraduate medical journal

authors： Athanasiou T,Patel V,Garas G,Ashrafian H,Shetty K,Sevdalis N,Panzarasa P,Darzi A,Paroutis S

更新日期：2016-10-01 00:00:00

abstract：:Two coronary prognostic indices for patients treated in a coronary care unit, namely the Norris Index and the Chapman-Gray Index were compared. Both were found to be reliable but the Chapman-Gray Index with its ready reckoner was more convenient and was subject to fewer subjective data. ...

journal_title：Postgraduate medical journal

authors： Habib T,Taylor DJ,Dalton R

更新日期：1979-01-01 00:00:00

abstract：:This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patient...

journal_title：Postgraduate medical journal

authors： Anderson G

更新日期：1983-01-01 00:00:00

abstract：:Thiazide diuretics used alone to treat hypertension can cause hypokalaemia in a substantial proportion of patients. The possibility exists that any benefit of reducing high blood pressure by such treatment may be offset by an increased mortality due to arrhythmias initiated by hypokalaemia. ...

journal_title：Postgraduate medical journal

authors： Poole-Wilson PA

更新日期：1983-01-01 00:00:00

abstract：:A case of primary purulent meningococcal pericarditis presenting with chest pain, hypotension and cardiac tamponade followed by oliguric renal failure is reported. Treatment with antibiotics and surgical drainage was successful. ...

journal_title：Postgraduate medical journal

authors： Ramsdale DR,Kaul TK,Coulshed N

更新日期：1985-12-01 00:00:00

abstract：:By comparison with other calcium antagonist drugs, amlodipine has unique pharmacokinetic properties that are probably attributable to its chemical structure and positive ionic charge at physiological pH. Thus, amlodipine undergoes gradual absorption from the gastro-intestinal tract and is widely distributed throughout...

journal_title：Postgraduate medical journal

authors： Elliott HL,Meredith PA

更新日期：1991-01-01 00:00:00

abstract：:The effect of beta-blockers in improving exercise tolerance in angina pectoris can be accounted for by the reduction in heart rate and arterial pressure than they produce. The failure of a few patients to respond despite reduction in heart rate and the failure of those who do respond to obtain the full expected benefi...

journal_title：Postgraduate medical journal

authors： Robinson BF

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Essential Skills in the Management of Surgical Cases (ESMSC) is a novel 3-day international undergraduate surgical masterclass. Its current curriculum (Cores integrated for Research-Ci4R) is built on a tetracore, multiclustered architecture combining high-fidelity and low-fidelity simulation-based learning (...

journal_title：Postgraduate medical journal

authors： Sideris M,Hanrahan J,Tsoulfas G,Theodoulou I,Dhaif F,Papalois V,Papagrigoriadis S,Velmahos G,Turner P,Papalois A

更新日期：2018-05-01 00:00:00

abstract：:The monocyte function, as measured by phagocytosis and killing of Candida albicans and Candida pseudotropicalis by peripheral blood monocytes, was found impaired in a patient with cirrhosis of the liver on two separate determinations before the occurrence of bleeding from oesophageal varices. Unexpectedly, Hodgkin's d...

journal_title：Postgraduate medical journal

authors： Dan M,Hassner A,Jedwab M,Shibolet S

更新日期：1984-07-01 00:00:00