The value of 5-aminosalicylic acid in inflammatory bowel disease for patients intolerant or allergic to sulphasalazine.

Abstract:

:The use of sulphasalazine in inflammatory bowel disease is often limited by intolerance or allergy. In previous studies 5-aminosalicylic acid (5ASA), the active ingredient of sulphasalazine, coated with an acrylic resin, has been shown to be as effective as sulphasalazine in maintaining remission. In this study coated 5ASA was given to 37 patients intolerant or allergic to sulphasalazine. Thirty-three patients have tolerated 5ASA satisfactorily, and most experienced improved control of their disease. Four patients reported similar side effects with sulphasalazine and 5ASA.

journal_name

Postgrad Med J

authors

Donald IP,Wilkinson SP

doi

10.1136/pgmj.61.722.1047

subject

Has Abstract

pub_date

1985-12-01 00:00:00

pages

1047-8

issue

722

eissn

0032-5473

issn

1469-0756

journal_volume

61

pub_type

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