Propofol ('Diprivan') by intravenous infusion with nitrous oxide: dose requirements and haemodynamic effects.

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of spinal tuberculosis (ST) is difficult and it commonly presents at an advanced stage. The management and follow up is complicated by a lack of guidance on the appropriate use and interpretation of spinal magnetic resonance studies (MR). AIMS:A retrospective study was performed at a UK centre...

journal_title：Postgraduate medical journal

authors： Cormican L,Hammal R,Messenger J,Milburn HJ

更新日期：2006-01-01 00:00:00

abstract：:A patient with carcinoma of the stomach invading multiple adjacent organs and fungating through the anterior abdominal wall was treated by en bloc multiple organ resection and abdominal wall reconstruction. The patient is alive and well at the time of writing, six months after the operation. The rationale for embarkin...

journal_title：Postgraduate medical journal

authors： Chu KM,Lai DT,Stern HS,Sheldon DM

更新日期：1995-05-01 00:00:00

abstract：:Sir William Osler organized a journal club at McGill University in 1875, and several authors suggest that journal clubs were found in certain European countries (in particular, Germany and England) prior to that time. The evolution and development of the journal club, however, has not been recorded in the medical lite...

journal_title：Postgraduate medical journal

authors： Linzer M

更新日期：1987-06-01 00:00:00

abstract：:The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

journal_title：Postgraduate medical journal

authors： Humphrey LJ,Estes NC

更新日期：1979-01-01 00:00:00

abstract：:The term "natural childbirth" denotes an approach to childbirth characterised by a bias towards physical and mental hygiene in the management of pregnancy and labour. It emerged in Britain in the interwar period, partly as a response to the growing interventionism of mainstream obstetrics. Its appeal since then has re...

journal_title：Postgraduate medical journal

authors： Moscucci O

更新日期：2003-03-01 00:00:00

abstract：:The body composition of the 17 members of the BMRES was studied using body weight and fat fold calipers, with measurements of whole body potassium and nitrogen. The full assessment was made just before departure from Birmingham and immediately on return. Daily observations of body weight and fat folds were made during...

journal_title：Postgraduate medical journal

authors： Harvey TC,James HM,Chettle DR

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:To identify the consultation activities of clinical ethics committees (CECs) in the UK and the views of CEC chairpersons regarding such activities. METHODS:An anonymous, password-protected online questionnaire was sent by e-mail to 70 CEC chairpersons. The questionnaire contained 14 items. RESULTS:Of the 70...

journal_title：Postgraduate medical journal

authors： Whitehead JM,Sokol DK,Bowman D,Sedgwick P

更新日期：2009-09-01 00:00:00

abstract：:Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

journal_title：Postgraduate medical journal

authors： Talbot K

更新日期：2002-09-01 00:00:00

abstract：:Ultrasound guidance has been reported to facilitate the performance of lumbar punctures (LPs). However, the use of ultrasound guidance has not yet received consistent conclusions. We performed a systematic review and meta-analysis to determine the efficacy of ultrasound-guided LPs. PubMed, Embase and the Cochrane Libr...

journal_title：Postgraduate medical journal

authors： Shu L,Huang J,Liu JC

更新日期：2021-01-01 00:00:00

abstract：:We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient...

journal_title：Postgraduate medical journal

authors： Baruch Y,Ben-Arie Y,Kerner H,Lorber M,Best LA,Gershoni-Baruch R

更新日期：1991-04-01 00:00:00

abstract：:The effective management of constipation in childhood requires an understanding of the ways that the physical and psychological factors interact. The early difficulty with defecation that leads to pain, fear, and refusal to use the pot or lavatory often progresses to the formation of vicious cycles of increasing faeca...

journal_title：Postgraduate medical journal

authors： Clayden G,Keshtgar AS

更新日期：2003-11-01 00:00:00

abstract：:Haemorrhagic infarction of the breast induced by anticoagulant therapy is rare and has been infrequently reported in the literature. The following report illustrates such a case in which there was development of massive haemorrhagic infarction of the breast during treatment with nicoumalone for deep venous thrombosis ...

journal_title：Postgraduate medical journal

authors： Banik S,Brun C

更新日期：1982-01-01 00:00:00

abstract：:A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

journal_title：Postgraduate medical journal

authors： Shee CD

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:To explore the relationship between cognitive impairment and conventional measures of disability in multiple sclerosis (MS), quality of life (QOL) and employment status using the brief international cognitive assessment for multiple sclerosis (BICAMS) in the routine outpatient clinic. METHODS:62 patients wi...

journal_title：Postgraduate medical journal

authors： Campbell J,Rashid W,Cercignani M,Langdon D

更新日期：2017-03-01 00:00:00

abstract：:This paper reviews the adverse events reported by 12,917 patients treated with cephalexin in formal clinical trials. Six percent of all patients reported adverse events, and in 3% the association with the drug was thought to be definite or probable. In the remaining 3%, the relationship was uncertain. The gastrointest...

journal_title：Postgraduate medical journal

authors： Burt RA

更新日期：1983-01-01 00:00:00

abstract：:The abnormalities of erythrocytes, leucocytes, thrombocytes and coagulation that have been reported, particularly in more recent years, to be associated with hyperthyroidism are surveyed. Several areas are highlighted where further investigations could lead to clinically useful insights, improved information about the...

journal_title：Postgraduate medical journal

authors： Ford HC,Carter JM

更新日期：1988-10-01 00:00:00

abstract：:Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

journal_title：Postgraduate medical journal

authors： Ciclitira PJ,Ellis HJ

更新日期：1987-09-01 00:00:00

abstract：:Although several modalities are available to investigate oesophageal motility disorders, manometry is the gold standard. The procedure is increasingly available in district general hospitals but the clinical utility of this investigation in this setting remains unclear. The aim in this study was to evaluate the use an...

journal_title：Postgraduate medical journal

authors： Ragunath K,Williams JG

更新日期：2002-01-01 00:00:00

abstract：:Three studies reported here have confirmed that lornoxicam is effective in osteoarthritis and the ideal dose appears to be 12 mg daily. Overall, lornoxicam appears to be a useful drug in the treatment of both osteo- and rheumatoid arthritis, from the data presently available. ...

journal_title：Postgraduate medical journal

authors： Berry H,Ollier S

更新日期：1990-01-01 00:00:00

abstract：:The acute haemodynamic effects of endralazine, a new hydralazine-like vasodilating agent, were studied in 6 patients with stable angina pectoris and proven coronary artery disease. Twenty minutes after intravenous administration of 5 mg endralazine heart rate and cardiac index increase, while mean arterial blood press...

journal_title：Postgraduate medical journal

authors： van der Wall EE,de Feyter PJ,Res JC,Roos JP,van Engelen CL

更新日期：1983-01-01 00:00:00

abstract：:The use of self-expanding metal stents can markedly improve the care of patients with inoperable oesophageal malignancy. The stents can be easily introduced without the need for general anaesthesia. They have fewer complications during insertion than rigid stents and fewer complications than laser therapy. With these ...

journal_title：Postgraduate medical journal

authors： Murphy GJ

更新日期：1995-08-01 00:00:00

abstract：INTRODUCTION:Potentially inappropriate medication (PIM) prescribing is a global problem. Limited data are available on the prevalence of PIMs in elderly patients with chronic kidney disease (CKD). We examined the PIM prevalence in elderly patients with CKD, the most common drugs implicated and the levels of polypharmac...

journal_title：Postgraduate medical journal

authors： Jones SA,Bhandari S

更新日期：2013-05-01 00:00:00

abstract：AIM:To obtain the views of specialist registrars on specialty care in the community. METHOD:Specialist registrars from five Deaneries in England completed an online questionnaire about their views on employment prospects, the role of specialty care in the community, and the need for additional training in this area. ...

journal_title：Postgraduate medical journal

authors： Azam N,Moshkovska T,Mayberry JF

更新日期：2007-01-01 00:00:00

abstract：:There is an increasing awareness on the part both of the media and the profession of the need to co-operate in providing information and education on medical matters. This co-operation should be strongly encouraged. Where children are concerned the opportunities for education are great. ...

journal_title：Postgraduate medical journal

authors： Jolly H

更新日期：1978-03-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread in nearly 200 countries in less than 4 months since its first identification; accordingly, the coronavirus disease 2019 (COVID 2019) has affirmed itself as a clinical challenge. The prevalence of pre-existing cardiovascular diseases in patients wi...

journal_title：Postgraduate medical journal

authors： Sisti N,Valente S,Mandoli GE,Santoro C,Sciaccaluga C,Franchi F,Cameli P,Mondillo S,Cameli M

更新日期：2020-07-30 00:00:00

abstract：:Studies on hypouricaemia observed in a patient with 48,XXYY syndrome revealed an abnormality in renal urate handling. His renal urate clearance was abnormally increased. Inosine administration and provocative tests using probenecid and pyrazinamide identified an isolated renal tubular abnormality with increased urate ...

journal_title：Postgraduate medical journal

authors： Nakajima H,Tajima K,Nakajima T,Iida S,Sumi S,Kono N,Moriwaki K,Nonaka K,Tarui S

更新日期：1986-03-01 00:00:00

abstract：:The prognosis of patients with metastatic adrenal cortical carcinoma is poor, and their disabling symptoms are usually unresponsive to conventional therapy. A patient with Cushing's syndrome secondary to a secretory adrenal cortical carcinoma was treated with octreotide, endocrine therapy and chemotherapy having faile...

journal_title：Postgraduate medical journal

authors： Pandha HS,Harrington K,Saini S,Lynn J,Peters M,Waxman J

更新日期：1995-04-01 00:00:00

abstract：:Herniation of a thoracic disc in an acromegalic giant is reported. Degenerative changes in the spine in association with dorsal kyphosis, and the additional strain, resulted in the disc prolapse. ...

journal_title：Postgraduate medical journal

authors： Chhang WH,Sharma BS,Dash RJ,Kak VK

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

journal_title：Postgraduate medical journal

authors： Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

更新日期：2016-09-01 00:00:00