A review of oesophageal manometry testing in a district general hospital.

abstract：:Placebo, used here to mean an inert treatment given as if it was a real treatment, means lots of different things to different people. The structure of the article is that it begins by talking about the technical use of placebos in clinical trials, and the extent of the placebo response, then about the mechanism--"How...

journal_title：Postgraduate medical journal

authors： McQuay HJ,Moore RA

更新日期：2005-03-01 00:00:00

abstract：:A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

journal_title：Postgraduate medical journal

authors： Shee CD

更新日期：1988-05-01 00:00:00

abstract：:Coeliac disease is exacerbated by wheat gluten. A review of methods for the purification, identification and quantitation of wheat proteins to investigate coeliac disease is presented. Recent developments including amino acid sequencing and expression of wheat protein peptides in E. coli should permit characterization...

journal_title：Postgraduate medical journal

authors： Ciclitira PJ,Ellis HJ

更新日期：1987-09-01 00:00:00

abstract：:A case of adenocarcinoma of the lung, in which high titre anticardiolipin antibodies were associated with recurrent venous thromboses resistant to all forms of therapy, is described. It is suggested that such an autoimmune response may be a contributory factor in the para-neoplastic development of vascular thromboses....

journal_title：Postgraduate medical journal

authors： Shaukat MN,Hughes P

更新日期：1990-04-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：AIM:To obtain the views of specialist registrars on specialty care in the community. METHOD:Specialist registrars from five Deaneries in England completed an online questionnaire about their views on employment prospects, the role of specialty care in the community, and the need for additional training in this area. ...

journal_title：Postgraduate medical journal

authors： Azam N,Moshkovska T,Mayberry JF

更新日期：2007-01-01 00:00:00

abstract：:Abnormalities in the serum concentrations of calcium, phosphate, parathyroid hormone and vitamin D develop with declining renal function, leading in turn to renal osteodystrophy. Observational data now suggest that these disturbances in bone and mineral metabolism play an important role in the development of vascular ...

journal_title：Postgraduate medical journal

authors： Connor A

更新日期：2009-05-01 00:00:00

abstract：:Pregnancy is a time of great maternal physiological and metabolic changes. This affects the biochemical and haematological parameters used in the assessment of liver disease, and it is important to appreciate the different reference ranges in pregnancy to facilitate recognition of liver disorders in pregnancy. Due to ...

journal_title：Postgraduate medical journal

authors： Mackillop L,Williamson C

更新日期：2010-03-01 00:00:00

abstract：:Verrucous carcinoma is a rare skin malignancy of squamous cell origin. It is characterised by negligible cellular atypia and a low mitotic rate. These are reflected in slow locally invasive behaviour and very infrequent metastatic spread. The tumour is also recognised in oral and anogenital sites. Cutaneous lesions pr...

journal_title：Postgraduate medical journal

authors： Munro NA,Smith C,Purushotham AD

更新日期：1999-11-01 00:00:00

abstract：:The effects of nilvadipine on the peripheral circulation in the lower extremities using a duplex system of two-dimensional colour and pulse Doppler ultrasonography were studied in 32 patients with type 2 diabetes mellitus and mild essential hypertension. The patients (19 men and 13 women) were randomly divided into tr...

journal_title：Postgraduate medical journal

authors： Sone H,Okuda Y,Mizutani M,Kawakami Y,Bannai C,Yamashita K

更新日期：1995-10-01 00:00:00

abstract：:Twelve healthy volunteers took part in a randomised, double-blind, balanced, cross-over study to investigate the effect of misoprostol on the pharmacokinetics of propranolol. The subjects took propranolol 80 mg twice daily by mouth plus either misoprostol 400 micrograms twice daily or placebo by mouth for 14.5 days, f...

journal_title：Postgraduate medical journal

authors： Bennett PN,Fenn GC,Notarianni LJ,Lee CE

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

journal_title：Postgraduate medical journal

authors： Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

更新日期：2016-09-01 00:00:00

abstract：:Learning curves graphically represent the relationship between learning effort and learning outcome. Learning curves are increasingly used in research, the design of randomised controlled trials, the assessment of competency, healthcare education and training programme design. In this review we have outlined the princ...

journal_title：Postgraduate medical journal

authors： Valsamis EM,Chouari T,O'Dowd-Booth C,Rogers B,Ricketts D

更新日期：2018-09-01 00:00:00

abstract：:Amniotic fluid embolism (AFE) associated with disseminated intravascular clotting (DIC) is usually fatal. Such a combination generally occurs at the term of pregnancy or in the immediate postpartum period. A case of AFE with DIC following a hypertonic-saline-induced abortion, is reported. The patient was in the midtri...

journal_title：Postgraduate medical journal

authors： Ballas S,Lessing JB,Michowitz M

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:The post mortem examination or autopsy is a trusted method of identifying the cause of death. Patients and their families may oppose an autopsy for a variety of reasons, including fear of mutilation or owing to religious and personal beliefs. Imaging alternatives to autopsy have been explored, which may prov...

journal_title：Postgraduate medical journal

authors： Ahmad MU,Sharif KA,Qayyum H,Ehsanullah B,Balyasnikova S,Wale A,Shanmuganandan A,Siddiqui MRS,Athanasiou T,Kemp GJ

更新日期：2017-11-01 00:00:00

abstract：:A patient is described who presented with the classical symptomatology and profound electrolyte disturbance of the Verner-Morrison syndrome due to a pancreatic apudoma secreting vasoactive intestinal polypeptide (VIP). Diagnosis was confirmed by plasma VIP as measured by a radio-immunoassay technique now available. It...

journal_title：Postgraduate medical journal

authors： Devine BL,Carmichael HA,Russell RI,Joffe SN

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:The International Diabetes Attitudes, Wishes, and Needs (DAWN) programmes have shown the existence of a critical gap in self management support and access to the support system. This study aims to evaluate the effectiveness of the diabetes mellitus (DM) self management programme, with partnership between gen...

journal_title：Postgraduate medical journal

authors： Lee A,Siu CF,Leung KT,Lau LC,Chan CC,Wong KK

更新日期：2011-10-01 00:00:00

abstract：:Healthcare workers have a high risk of occupational exposure, more so in developing countries, with high incidence of blood borne diseases and prevalence of unsafe practices. Among the various blood borne diseases, the most common and important ones are HIV infection, hepatitis B, and hepatitis C. Most of the occupati...

journal_title：Postgraduate medical journal

authors： Varghese GM,Abraham OC,Mathai D

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Epidemiological and family studies suggest that lung cancer results from the combined effects of age, smoking and genetic factors. Chronic obstructive pulmonary disease (COPD) is also an independent risk factor for lung cancer and coexists in 40-60% of lung cancer cases. METHODS:In a two-stage case-control ...

journal_title：Postgraduate medical journal

authors： Young RP,Hopkins RJ,Hay BA,Epton MJ,Mills GD,Black PN,Gardner HD,Sullivan R,Gamble GD

更新日期：2009-10-01 00:00:00

abstract：:Psychiatric symptoms are well recognized as a feature of patients with primary hyperparathyroidism. We have applied a standardized psychiatric interview to 15 patients before and after surgery. Thirteen had a lower 'psychiatric score' (less psychiatric morbidity) after surgery and improvements were particularly seen i...

journal_title：Postgraduate medical journal

authors： McAllion SJ,Paterson CR

更新日期：1989-09-01 00:00:00

abstract：:Fibrosing colonopathy is a recently described complication of cystic fibrosis, of unknown aetiology but possibly related to treatment with high-dose pancreatic enzyme supplements. We have used a whole gut perfusion technique to study subclinical gut inflammation in cystic fibrosis patients; concentrations of haemoglob...

journal_title：Postgraduate medical journal

authors： Croft NM,Marshall TG,Ferguson A

更新日期：1996-03-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread in nearly 200 countries in less than 4 months since its first identification; accordingly, the coronavirus disease 2019 (COVID 2019) has affirmed itself as a clinical challenge. The prevalence of pre-existing cardiovascular diseases in patients wi...

journal_title：Postgraduate medical journal

authors： Sisti N,Valente S,Mandoli GE,Santoro C,Sciaccaluga C,Franchi F,Cameli P,Mondillo S,Cameli M

更新日期：2020-07-30 00:00:00

abstract：BACKGROUND:This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices we...

journal_title：Postgraduate medical journal

authors： Gillen P,Sharifuddin SF,O'Sullivan M,Gordon A,Doherty EM

更新日期：2018-04-01 00:00:00

abstract：:A case of deliberate overdose of barium sulphide in a psychiatric setting is presented, with resulting flaccid paralysis, malignant arrhythmia, respiratory arrest and severe hypokalaemia, but ultimately with complete recovery. The degree of paralysis appears to be related directly to serum barium levels. The value of ...

journal_title：Postgraduate medical journal

authors： Thomas M,Bowie D,Walker R

更新日期：1998-09-01 00:00:00

abstract：:The earliest manifestations of leukaemia often include rheumatic signs and symptoms. Arthritis is a well recognised complication of leukaemia in children, but acute and chronic leukaemia may also cause arthritis in adults. Leukaemic arthritis may occur at any time during the course of leukaemia and may be the presenti...

journal_title：Postgraduate medical journal

authors： Usalan C,Ozarslan E,Zengin N,Büyükaýk Y,Güllü YH

更新日期：1999-07-01 00:00:00

abstract：:We report a patient who developed persistent nephrogenic diabetes insipidus associated with renal tubular acidosis, renal resistance to parathyroid hormone, aminoaciduria and proximal tubule pattern proteinuria in the presence of a reduced glomerular filtration rate (19-24 ml/min). A review of the previous reports of ...

journal_title：Postgraduate medical journal

authors： Neithercut WD,Spooner RJ,Hendry A,Dagg JH

更新日期：1990-06-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:A 61-year-old patient with treated Conn's syndrome due to multiple bilateral adrenocortical adenomata developed primary hyperparathyroidism. At operation, a parathyroid adenoma and a thyroid colloid nodule were found. Although adrenocortical adenomata and hyperplasia are common findings in multiple endocrine adenopath...

journal_title：Postgraduate medical journal

authors： Fertig A,Webley M,Lynn JA

更新日期：1980-01-01 00:00:00

abstract：:A case of seminoma of the testis complicated by an extensive granulomatous reaction is reported. This reaction was so florid that a benign condition was initially considered until further material for histology was examined and the correct diagnosis made. ...

journal_title：Postgraduate medical journal

authors： Pickard WR,Clark AH,Abel BJ

更新日期：1983-05-01 00:00:00

abstract：:The effect of digoxin (0.25 mg t.d.s.) given orally for 5 days, on sodium excretion, plasma renin activity, plasma aldosterone and blood pressure has been studied in 6 normotensive subjects, on a constant sodium intake. Average serum digoxin level measured in 5 subjects on the 5th day of treatment was in the upper ran...

journal_title：Postgraduate medical journal

authors： Cappuccio FP,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1986-04-01 00:00:00