Renal hypouricaemia in a patient with 48,XXYY syndrome.

abstract：:Micronutrients play a central part in metabolism and in the maintenance of tissue function. An adequate intake therefore is necessary, but provision of excess supplements to people who do not need them may be harmful. Single micronutrient deficiency states are comparatively easily recognised and treated. Subclinical d...

journal_title：Postgraduate medical journal

authors： Shenkin A

更新日期：2006-09-01 00:00:00

abstract：:This review presents our experience in the use of propranolol in the management of cardiac infarction. The drug has now been shown to have a definite place, not only in the prevention of cardiac infarction, but also in the treatment of some of the complications. The drug has also been advocated because it may minimiz...

journal_title：Postgraduate medical journal

authors： Sloman G,Hunt D,Ross D

更新日期：1976-01-01 00:00:00

abstract：:Sir William Osler organized a journal club at McGill University in 1875, and several authors suggest that journal clubs were found in certain European countries (in particular, Germany and England) prior to that time. The evolution and development of the journal club, however, has not been recorded in the medical lite...

journal_title：Postgraduate medical journal

authors： Linzer M

更新日期：1987-06-01 00:00:00

abstract：:Two female patients who suffered from drug-induced thrombocytopenic purpura and subendocardial myocardial infarction are presented. One of them died from cerebral haemorrhage and diffuse subendocardial punctate haemorrhages were found at post-mortem. The abnormal haemostasis which is associated with thrombocytopenia m...

journal_title：Postgraduate medical journal

authors： Fireman Z,Yust I,Zahavi J,Kahn Y,Abramov LA

更新日期：1979-01-01 00:00:00

abstract：:Thirteen patients with mild primary hyperparathyroidism who were taking thiazide diuretics intermittently for periods of up to 18 months were followed up for a mean of 5.3 years. No significant difference was found in either plasma total calcium corrected for albumin or whole blood ionized calcium in these patients be...

journal_title：Postgraduate medical journal

authors： Farquhar CW,Spathis GS,Barron JL,Levin GE

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:To examine the current attitudes towards the prevention of venous thromboembolism among a cohort of surgeons. DESIGN:A postal survey, comprising a questionnaire covering various aspects of venous thromboembolism prophylaxis was sent to all (n=84) consultant general surgeons in Wales. RESULTS:Replies were re...

journal_title：Postgraduate medical journal

authors： Williams EV,Williams RS,Hughes JL,Williams KL,Foster ME,Lewis MH

更新日期：2002-02-01 00:00:00

abstract：:Overdosage with cardiac glycosides is well documented, but not usually fatal. A case is described in which cardiac arrest in asystole was associated with a serum digoxin level of 50-4 microgram/1, the highest concentration yet reported after oral administration. ...

journal_title：Postgraduate medical journal

authors： Nicholls DP

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Despite obesity being a major risk factor for ischaemic stroke (IS), the association between body mass index (BMI) and IS in patients with hypertension remains uncertain. OBJECTIVE:To assess the association between BMI and IS among elderly hypertensive patients in China. METHODS AND RESULTS:We recruited 35...

journal_title：Postgraduate medical journal

authors： Huang J,Liu L,Yu YL,Chen CL,Lo K,Huang YQ,Tang ST,Feng YQ

更新日期：2020-03-27 00:00:00

abstract：AIM:To obtain the views of specialist registrars on specialty care in the community. METHOD:Specialist registrars from five Deaneries in England completed an online questionnaire about their views on employment prospects, the role of specialty care in the community, and the need for additional training in this area. ...

journal_title：Postgraduate medical journal

authors： Azam N,Moshkovska T,Mayberry JF

更新日期：2007-01-01 00:00:00

abstract：:Forty-five healthy men aged 21-34 years took part in a double-blind, parallel-group, placebo-controlled study of the effects of 28 days' treatment with lornoxicam 4 mg twice daily or indomethacin 50 mg twice daily on faecal blood loss and the endoscopic appearances of gastric and duodenal mucosa. After an initial endo...

journal_title：Postgraduate medical journal

authors： Warrington SJ,Debbas NM,Farthing M,Horton M,Johnston A,Thillainayagam A,Turner P,Ferber H

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Post-radiation large vessel injury has not received as much attention as microvascular irradiation injury. A few studies have shown that common carotid intima-media thickness (IMT) is increased after radiotherapy to the head and neck. However, in most of these studies, the irradiated subjects also had other ...

journal_title：Postgraduate medical journal

authors： Shariat M,Alias NA,Biswal BM

更新日期：2008-11-01 00:00:00

abstract：:This paper reviews the adverse events reported by 12,917 patients treated with cephalexin in formal clinical trials. Six percent of all patients reported adverse events, and in 3% the association with the drug was thought to be definite or probable. In the remaining 3%, the relationship was uncertain. The gastrointest...

journal_title：Postgraduate medical journal

authors： Burt RA

更新日期：1983-01-01 00:00:00

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：:Antenatal appendicular perforation leading to localized meconium peritonitis and intestinal obstruction is reported in a premature neonate. The baby was successfully treated by a limited ileocaecal resection. ...

journal_title：Postgraduate medical journal

authors： Narasimharao KL,Mitra SK,Pathak IC

更新日期：1987-11-01 00:00:00

abstract：:Thirty-one patients with radiolucent common bile duct stones received medical treatment. Nineteen had Rowachol, a terpene preparation, eight (42%) achieving complete stone disappearance within 3 to 48 months. Fifteen (including 3 of the above) took Rowachol with bile acid (chenodeoxycholic in 11, ursodeoxycholic in 4)...

journal_title：Postgraduate medical journal

authors： Somerville KW,Ellis WR,Whitten BH,Balfour TW,Bell GD

更新日期：1985-04-01 00:00:00

abstract：:Exercise is known to have a vast array of health benefits. It may however confer delirious effects on most body systems, with the cardiovascular system taking particular prominence. Athletes in particular are known to be at a higher risk for sudden cardiac death as a result of several cardiac adaptations which take pl...

journal_title：Postgraduate medical journal

authors： Abela M,Sammut L

更新日期：2017-12-01 00:00:00

abstract：:For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare professionals and their patients, helping to build a relationship of trust. But beware the fal...

journal_title：Postgraduate medical journal

authors： Beamish AJ,Foster JJ,Edwards H,Olbers T

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Circulating nitric oxide (NO) and lipid levels are closely associated with coronary artery disease (CAD). It is unclear whether the rs1799983 polymorphism in endothelial nitric oxide synthase (NOS3) gene is associated with plasma levels of NO and lipids. This systematic review and meta-analysis (Preferred Re...

journal_title：Postgraduate medical journal

authors： Luo Z,Jia A,Lu Z,Muhammad I,Adenrele A,Song Y

更新日期：2019-07-01 00:00:00

abstract：:Postherpetic neuralgia is defined as pain persisting, or recurring, at the site of shingles at least three months after the onset of the acute rash. Thus defined, at least half of shingles sufferers over the age of 65 years develop postherpetic neuralgia. In addition to increasing age, less important risk factors for ...

journal_title：Postgraduate medical journal

authors： Bowsher D

更新日期：1997-10-01 00:00:00

abstract：:The incidence, predisposing factors, management and outcome of toxic megacolon (TM) has been reviewed in 65 cases of severe ulcerative colitis (UC) and compared in 2 successive 6-year periods before and after January, 1973. Nineteen episodes of TM occurred in 18 patients. Despite a conscious aim towards earlier surger...

journal_title：Postgraduate medical journal

authors： Muscroft TJ,Warren PM,Asquith P,Montgomery RD,Sokhi GS

更新日期：1981-04-01 00:00:00

abstract：:There is considerable evidence to suggest that the identification and treatment of dyslipidaemia will reduce the risk of premature CHD, i.e. before the age of 65. Diagnosis of the cause of raised plasma lipid levels will enable appropriate decisions to be taken with regard to management. The cornerstone of treatment i...

journal_title：Postgraduate medical journal

authors： Betteridge DJ,Dodson PM,Durrington PN,Hughes EA,Laker MF,Nicholls DP,Rees JA,Seymour CA,Thompson GR,Winder AF

更新日期：1993-05-01 00:00:00

abstract：:Secondary hyperkalaemic paralysis is a rare condition often mimicking the Guillain-Barré syndrome. There have been a few case reports of hyperkalaemia caused by renal failure, trauma, and drugs where the presentation has been with muscle weakness. A case of hyperkalaemic paralysis caused by an angiotensin converting e...

journal_title：Postgraduate medical journal

authors： Dutta D,Fischler M,McClung A

更新日期：2001-02-01 00:00:00

abstract：:Strips form canine saphenous veins were incubated with (3H)-noradrenaline and mounted for superfusion. 5-Hydroxytryptamine (5-HT inhibited the release of tritium caused by sustained electrical stimulation (2 Hz, 150 mA, 0.1 msec) being about 10 times more potent than noradrenaline. 5-HT inhibited contractions induced ...

journal_title：Postgraduate medical journal

authors： Müller-Schweinitzer E

更新日期：1981-01-01 00:00:00

abstract：:Following the drinking of 150 g of alcohol and a large amount of intra-nasal cocaine a previously healthy 31 year old man developed severe retrosternal pain and circulatory failure. An electrocardiogram showed supra-ventricular tachycardia with widespread ischaemic changes. Following electrical cardioversion electroca...

journal_title：Postgraduate medical journal

authors： Boag F,Havard CW

更新日期：1985-11-01 00:00:00

abstract：:The side effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) on the stomach is undoubtedly a serious public health problem contributing significantly to the morbidity and mortality of patients receiving these drugs. However, the damage of NSAIDs is not confined to the stomach. Indeed the short term ...

journal_title：Postgraduate medical journal

authors： Adebayo D,Bjarnason I

更新日期：2006-03-01 00:00:00

abstract：:Essential tremor is the most common cause of tremor involving upper limbs, head and voice. The first line of treatment for limb tremor is pharmacotherapy with propranolol or primidone. However, these two drugs reduce the tremor severity by only half. In medication refractory and functionally disabling tremor, alternat...

journal_title：Postgraduate medical journal

authors： Sharma S,Pandey S

更新日期：2020-02-01 00:00:00

abstract：:There is evidence that acetylcholine antagonists at the neuromuscular junction and elsewhere can act by blocking the ionic channels opened by acetylcholine as well as by competing with acetylcholine for receptor sites. This type of uncompetitive antagonism can be distinguished from competitive antagonism in various wa...

journal_title：Postgraduate medical journal

authors： Rang HP

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the reasons why primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting. METHODS:Twenty four past or current postgraduate diploma students of the family medicine unit (FMU) of the University of Hong Kong participated in three fo...

journal_title：Postgraduate medical journal

authors： Lam TP,Lam KF,Tse EY

更新日期：2006-06-01 00:00:00

abstract：:Although many of the fundamental biological features of toxoplasmosis are today well appreciated, the practical problem of prevention of its most serious consequence--disabling congenital disease, remains unsolved. The reasons vary in different communities, but are concerned with detection of the chief mode of spread,...

journal_title：Postgraduate medical journal

authors： Williams H

更新日期：1977-10-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been caused the greatest pandemic of our century. Many of the deaths related to it are due to a systemic inflammatory response, which has been called 'cytokine storm'. OBJECTIVES:We developed a comprehensive review of the pathophysiology mec...

journal_title：Postgraduate medical journal

authors： Mélo Silva Júnior ML,Souza LMA,Dutra REMC,Valente RGM,Melo TS

更新日期：2020-10-02 00:00:00