Drugs and ionic channels: mechanisms and implications.

abstract：:A child with the isolated anomaly of azygos continuation of the inferior vena cava is presented. The interest of this abnormality lies in its detection as a mediastinal mass on the chest radiograph. Computed tomography with intravenous contrast enhancement is the method of choice to diagnose this venous anomaly. Aware...

journal_title：Postgraduate medical journal

authors： Beedie RJ,Yeo W,Morcos SK

更新日期：1989-04-01 00:00:00

abstract：:Two hundred and thirty-three patients with renal amyloidosis were studied in an attempt to identify the incidence and pattern of the disease in northern India. The incidence of amyloidosis was 1.01% of 6431 post-mortems and 8.4% of 1980 renal biopsies from patients who presented with clinical evidence of glomerular di...

journal_title：Postgraduate medical journal

authors： Chugh KS,Datta BN,Singhal PC,Jain SK,Sakhuja V,Dash SC

更新日期：1981-01-01 00:00:00

abstract：:A case of Meckel's diverticulum in a middle-aged man presenting acutely with haematemesis and melaena is reported. Such a presentation has not to our knowledge been previously reported in this age group. ...

journal_title：Postgraduate medical journal

authors： Shaunak S,O'Donohue J

更新日期：1983-12-01 00:00:00

abstract：:The Chancellor of the Exchequer's recent announcements to devolve decision making power from Whitehall to 30 English regions provide a challenge to use devolution to deliver more favourable health outcomes. However evaluation of devolved health models internationally is scarce, because it is rarely considered. Evidenc...

journal_title：Postgraduate medical journal

authors： Doyle Y,Johnstone P

更新日期：2016-05-01 00:00:00

abstract：:We report the case of a 58 year old man in whom an unusually prolonged infection with Toxoplasma gondii was the presenting feature of an underlying non-Hodgkin's lymphoma. This case demonstrates the particular usefulness of the IgM ELISA test in monitoring disease activity. ...

journal_title：Postgraduate medical journal

authors： Dudley NJ,Balfour AH

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVES:Effective communication is a vital part of good clinical care. Traditionally bleep systems have been used as the mainstay of communication. Mobile technology is increasingly seen as a quicker, easier and more reliable method of communication. Our objective was to assess the use of mobile devices within a typ...

journal_title：Postgraduate medical journal

authors： Martin G,Janardhanan P,Withers T,Gupta S

更新日期：2016-09-01 00:00:00

abstract：:In the Balkan context education in general practice varies greatly and it is in different stages of reorganisation and curriculum development. The postgraduate training in family medicine in Albania started in January 1997 with the goal of providing future family doctors with the proper knowledge, skills, attitudes, a...

journal_title：Postgraduate medical journal

authors： Rrumbullaku L,Theodorakis PN,Pulluqi P,Lionis C,Trell E

更新日期：2002-05-01 00:00:00

abstract：:Epilepsy is a common neurological disorder, prevalent in about 1% of the population. Almost half of the patients with epilepsy are women. Epilepsy and antiepileptic drugs can affect each aspect of the female human life cycle which includes menstrual cycle, contraception, fertility, conception, pregnancy and menopause....

journal_title：Postgraduate medical journal

authors： Gooneratne IK,Wimalaratna S

更新日期：2016-09-01 00:00:00

abstract：:We report a case of persistent chorea as a manifestation of thyrotoxicosis. The chorea was severe and persisted after the patient was rendered euthyroid. Dopamine antagonists only partially suppressed the involuntary movements during the first few months. It was eventually controlled with haloperidol, but whenever she...

journal_title：Postgraduate medical journal

authors： Javaid A,Hilton DD

更新日期：1988-10-01 00:00:00

abstract：:A total of 187 heart failure patients aged 65-92 years, with pretreatment serum creatinine levels below 200 mumol/l, were monitored for more than 12 months on angiotensin-converting enzyme (ACE) inhibitor therapy. Optimal ACE inhibitor dosage was found in 27% of patients, while a significant deterioration in renal fun...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：1999-05-01 00:00:00

abstract：:Warfarin, a vitamin K antagonist, is the most widely used oral anticoagulant in the world. It is cheap and effective, but its use is limited in many patients by unpredictable levels of anticoagulation, which increases the risk of thromboembolic or haemorrhagic complications. It also requires regular blood monitoring a...

journal_title：Postgraduate medical journal

authors： Saraf K,Morris PD,Garg P,Sheridan P,Storey R

更新日期：2014-09-01 00:00:00

abstract：:The differing aspects of fibrocystic disease are presented. The various histological components making up the breast account for the variegated presentation of symptoms and findings. Pain, tenderness and nodularity represent the greatest problem with the former two prompting the patient to seek relief. The latter symp...

journal_title：Postgraduate medical journal

authors： Humphrey LJ,Estes NC

更新日期：1979-01-01 00:00:00

abstract：:Ischaemic heart disease (IHD) related mortality has been on the decline, although its prevalence has been on the rise since the late 1970s. One of the contributing factors to this decline has been improved diagnosis and therapeutic management. Every clinician seeks to answer four key questions while evaluating patient...

journal_title：Postgraduate medical journal

authors： Raj V,Agrawal SK

更新日期：2010-09-01 00:00:00

abstract：:The present anti-racial discrimination legislation in the United Kingdom is embodied in the 1976 Race Relations Act. In essence this Act attempts to avoid any form of direct or indirect discrimination on the basis of racial or ethnic origin. However, health professionals are acutely aware that there are important raci...

journal_title：Postgraduate medical journal

authors： Bedi R,MacEwen M

更新日期：1990-12-01 00:00:00

abstract：:Helicobacter pylori is associated with gastritis, peptic ulcers and gastric malignancies. Little attention has been paid to the possibility that it may also have a role in the pathogenesis of reflux oesophagitis. This is especially true in elderly patients who have life-long infection and provide an ideal group to stu...

journal_title：Postgraduate medical journal

authors： Liston R,Pitt MA,Banerjee AK

更新日期：1996-04-01 00:00:00

abstract：PURPOSE OF THE STUDY:The aim of this study was to investigate the association of fluid overload, measured by bioelectrical impedance vector analysis (BIVA) and also by accumulated fluid balance, with 30-day mortality rates in patients admitted to the emergency department (ED). DESIGN:We conducted a prospective observa...

journal_title：Postgraduate medical journal

authors： Kammar-García A,Pérez-Morales Z,Castillo-Martinez L,Villanueva-Juárez JL,Bernal-Ceballos F,Rocha-González HI,Remolina-Schlig M,Hernández-Gilsoul T

更新日期：2018-07-01 00:00:00

abstract：:A 48 year old white woman was admitted to the hospital because of several bouts of migratory polyarthritis, weight loss, fever, and abdominal pain over a period of 15 months. She had been taking propylthiouracil 100 mg daily for three years for hyperthyroidism treatment. A test for antineutrophil cytoplasmic autoantib...

journal_title：Postgraduate medical journal

authors： Gaburri PD,Chebli JM,Attalla A,Pereira CM,Bonfante HL,Junior EV,Gaburri AK

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of acanthosis nigricans (AN) in type 2 diabetes mellitus (T2DM) and its correlation with various anthropometric measurements in Indians. METHODS:One hundred and fifty consecutive subjects with T2DM attending the diabetes clinic at a tertiary referral centre in North India were con...

journal_title：Postgraduate medical journal

authors： Grandhe NP,Bhansali A,Dogra S,Kumar B

更新日期：2005-08-01 00:00:00

abstract：:The case of a woman with a large benign villous papilloma of the rectum, presenting with sodium and water depletion and later complicated by persistent hypokalaemia, is described. The patient also suffered from primary hypogonadism and diabetes. ...

journal_title：Postgraduate medical journal

authors： Bamford JK,Galbraith HJ,Pender BW

更新日期：1965-04-01 00:00:00

abstract：:A patient with severe pulmonary hypertension due to pulmonary arteriolar obliteration complicating a long standing CREST variant of systemic sclerosis showed improvement in cardiac output and exercise tolerance during treatment with captopril, which was discontinued because of persistent systemic hypotension. It is su...

journal_title：Postgraduate medical journal

authors： Prouse PJ,Lahiri A,Gumpel JM

更新日期：1984-10-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:Tuberculosis of the appendix is rare. It is usually secondary to tuberculosis elsewhere in the abdomen. Tuberculosis of the appendix is not associated with any specific clinical features and diagnosis is revealed only after histopathological examination. Appendicectomy should be performed in all patients with abdomina...

journal_title：Postgraduate medical journal

authors： Singh MK,Arunabh,Kapoor VK

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:The leukocyte count is frequently used to evaluate suspected bacterial infections but estimates of its test performance vary considerably. We evaluated its accuracy for the detection of serious bacterial infections in febrile children. DESIGN:Prospective cohort study. SETTING:Paediatric emergency department...

journal_title：Postgraduate medical journal

authors： De S,Williams GJ,Hayen A,Macaskill P,McCaskill M,Isaacs D,Craig JC

更新日期：2015-03-01 00:00:00

abstract：:This study assesses the economic benefits of misoprostol in the prophylaxis of gastric ulcers larger than 0.3 cm in patients with osteoarthritis receiving non-steroidal anti-inflammatory drugs. Independent epidemiological data were obtained for patients in Scotland and the West Midlands. Co-diagnosis of arthritis with...

journal_title：Postgraduate medical journal

authors： Knill-Jones R,Drummond M,Kohli H,Davies L

更新日期：1990-08-01 00:00:00

abstract：:A 75 year old woman was treated for over three years with the somatostatin analogue, octreotide for an insulinoma. She had presented in a hypoglycaemic coma. C-peptide and insulin concentrations were both raised and an area of increased vascularity within the pancreas was shown by angiography. No lesion was found at l...

journal_title：Postgraduate medical journal

authors： Craig CE,Gallen IW

更新日期：2002-10-01 00:00:00

abstract：:Acute bacterial meningitis is a common neurological emergency and a leading cause of death and neurological disability worldwide. Diagnosis is based on clinical and microbiological findings with neuroimaging in the form of CT reserved for those with specific adverse clinical features or when an underlying cause such a...

journal_title：Postgraduate medical journal

authors： Hughes DC,Raghavan A,Mordekar SR,Griffiths PD,Connolly DJ

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the reasons why primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting. METHODS:Twenty four past or current postgraduate diploma students of the family medicine unit (FMU) of the University of Hong Kong participated in three fo...

journal_title：Postgraduate medical journal

authors： Lam TP,Lam KF,Tse EY

更新日期：2006-06-01 00:00:00

abstract：:A patient suffering from typhoid fever with severe pancytopenia is presented. Bone marrow examination revealed extensive haemophagocytosis which possibly contributed to the pancytopenia. ...

journal_title：Postgraduate medical journal

authors： Sood R,Roy S,Kaushik P

更新日期：1997-01-01 00:00:00

abstract：:Renal disease in Churg-Strauss syndrome is generally thought to be benign in nature, thereby distinguishing this rare condition from other necrotizing vasculitides. We report a case in which acute renal failure developed during the aggressive vasculitic phase of the illness requiring dialysis therapy. After one week o...

journal_title：Postgraduate medical journal

authors： Davenport A,McDicken I,Goldsmith HJ

更新日期：1988-09-01 00:00:00

abstract：:Quantitative lipoprotein level data was obtained from healthy subjects and patients with ischaemic heart disease or peripheral vascular disease in four European communities. Hypertriglyceridaemia, due mainly to an increase in VLDL triglyceride, was commoner in London and Uppsala than in Naples and Geneva. In three com...

journal_title：Postgraduate medical journal

authors： Lewis B,Carlson LA,Mancini M,Micheli H

更新日期：1975-01-01 00:00:00