Neurosarcoidosis: unusual presentations and considerations for diagnosis and management.

abstract：:There is evidence that acetylcholine antagonists at the neuromuscular junction and elsewhere can act by blocking the ionic channels opened by acetylcholine as well as by competing with acetylcholine for receptor sites. This type of uncompetitive antagonism can be distinguished from competitive antagonism in various wa...

journal_title：Postgraduate medical journal

authors： Rang HP

更新日期：1981-01-01 00:00:00

abstract：:We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions ...

journal_title：Postgraduate medical journal

authors： Burns A,Brown TM,Semple P

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of, and implement a diagnostic strategy for, imported helminth infection in the gastroenterology clinic. DESIGN:A retrospective study of eosinophil count and probable tropical exposure (phase I) followed by a prospective study of parasitological investigation (phase II). SETTING:G...

journal_title：Postgraduate medical journal

authors： Smith PJ,Theis B,McCartney S,Brown M

更新日期：2012-01-01 00:00:00

abstract：:This purports to be the first recorded case of carcinoma of the pancreas presenting as a mechanical obstruction of the colon. The literature relating to some other rare modes of presentation is reviewed, and a comment made on the desirability of routine post-mortem studies. ...

journal_title：Postgraduate medical journal

authors： Tresadern JC

更新日期：1981-01-01 00:00:00

abstract：:Sixty-nine infants were examined who presented with rectal bleeding in the first month of life. In 64% of these children no cause was found. Infantile diarrhoea, haemorrhagic disease of the newborn and anal fissure were the most common diagnoses made. The mortality in the entire group was less than 3%. It is concluded...

journal_title：Postgraduate medical journal

authors： Levene MI

更新日期：1979-01-01 00:00:00

abstract：:The effects of infusions of prostaglandin E1 (PGE1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. Thirteen patients with atherosclerotic vascular disease received intravenous PGE1 25 mg/kg/min for 6 hours daily for 5 days. Prostaglandin E1 had no effect on platelet uptake at athero...

journal_title：Postgraduate medical journal

authors： Sinzinger H,O'Grady J,Fitscha P

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:The leukocyte count is frequently used to evaluate suspected bacterial infections but estimates of its test performance vary considerably. We evaluated its accuracy for the detection of serious bacterial infections in febrile children. DESIGN:Prospective cohort study. SETTING:Paediatric emergency department...

journal_title：Postgraduate medical journal

authors： De S,Williams GJ,Hayen A,Macaskill P,McCaskill M,Isaacs D,Craig JC

更新日期：2015-03-01 00:00:00

abstract：:This paper reviews the development of cerebral scintigraphy from its early days of planar imaging with simple technetium-99m labelled compounds to the recent revival of the technique in the form of positron-emission and single-photon emission tomography. A short explanation of instrumentation and radiopharmaceuticals ...

journal_title：Postgraduate medical journal

authors： Shepstone BJ

更新日期：1988-01-01 00:00:00

abstract：:A patient with disseminated ovarian carcinoma presented with symptoms of hypocalcaemia secondary to hypomagnesaemia. The low serum magnesium (0.4 mmol/l) appeared to be due to renal leakage with no evidence of ureteric obstruction or hydronephrosis on intravenous urogram. Parathyroid hormone activity (serum levels and...

journal_title：Postgraduate medical journal

authors： Leese GP,Jung RT,Browning MC

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Current treatment for osteoarthritis (OA) is limited. Many patients with OA of the hand have areas of tender subcutaneous thickening in the forearm and upper scapular region. A pilot study showed an improvement in pain from OA at the first carpometacarpal joint after injection of such areas with 0.5% sodium ...

journal_title：Postgraduate medical journal

authors： Smith AS,Doré CJ,Dennis L,Julius A,Mackworth-Young CG

更新日期：2010-06-01 00:00:00

abstract：:Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features ar...

journal_title：Postgraduate medical journal

authors： Talbot K

更新日期：2002-09-01 00:00:00

abstract：:Left ventricular function was evaluated non-invasively in hypertensive patients treated with indapamide by means of echographically determined velocity of circumferential fibre shortening (VCF). A statistically significant reduction in mean systolic and diastolic blood pressure in both the standing and supine position...

journal_title：Postgraduate medical journal

authors： Horgan JH,O'Donovan A,Teo KK

更新日期：1981-01-01 00:00:00

abstract：:" Blo -Bag", a new disposable spacer device, has been tested in conjunction with Duovent metered dose inhaler. Duovent produced a significant bronchodilatation for the duration of the study. When delivered by the " Blo -Bag" it produced a significantly greater increase in peak expiratory flow rate than when delivered ...

journal_title：Postgraduate medical journal

authors： Woodcock A,Humberstone A,Kendall J,Pierce A

更新日期：1984-01-01 00:00:00

abstract：:A patient with long-standing ischaemic heart disease and severe low output congestive cardiac failure received numerous diuretics, which gradually became ineffective. Resistant oedema was treated by adding demeclocycline to the current diuretic regime of frusemide and metolazone. Diuresis resulted, oedema disappeared ...

journal_title：Postgraduate medical journal

authors： Bonser RS,Ghose RR

更新日期：1980-02-01 00:00:00

abstract：:Mild and self-limiting fever following bleomycin use is common, and a fatal hyperpyrexial response occurs rarely. In previously reported cases, such hyperpyrexia occurred either after the initial administration of the drug or during subsequent therapy following an initial pyrexial response. We describe a fatal hyperpy...

journal_title：Postgraduate medical journal

authors： Leung WH,Lau JY,Chan TK,Kumana CR

更新日期：1989-06-01 00:00:00

abstract：:Verrucous carcinoma is a rare skin malignancy of squamous cell origin. It is characterised by negligible cellular atypia and a low mitotic rate. These are reflected in slow locally invasive behaviour and very infrequent metastatic spread. The tumour is also recognised in oral and anogenital sites. Cutaneous lesions pr...

journal_title：Postgraduate medical journal

authors： Munro NA,Smith C,Purushotham AD

更新日期：1999-11-01 00:00:00

abstract：:Two-hundred and nine patients were entered into a prospective, randomized trial in order to determine whether a vertical or transverse abdominal incision is the more satisfactory in producing sound wounds. Ninety-six patients were randomized between paramedian and transverse incisions, and followed up for at least 1 y...

journal_title：Postgraduate medical journal

authors： Ellis H,Coleridge-Smith PD,Joyce AD

更新日期：1984-06-01 00:00:00

abstract：:Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis characterised clinically by frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic infiltrate with fibrosis, and therapeutically by a dramatic response to steroids. When so defined, AIP can be sub-classified into two subtyp...

journal_title：Postgraduate medical journal

authors： Kamisawa T,Chari ST,Lerch MM,Kim MH,Gress TM,Shimosegawa T

更新日期：2014-01-01 00:00:00

abstract：:A 48 year old white woman was admitted to the hospital because of several bouts of migratory polyarthritis, weight loss, fever, and abdominal pain over a period of 15 months. She had been taking propylthiouracil 100 mg daily for three years for hyperthyroidism treatment. A test for antineutrophil cytoplasmic autoantib...

journal_title：Postgraduate medical journal

authors： Gaburri PD,Chebli JM,Attalla A,Pereira CM,Bonfante HL,Junior EV,Gaburri AK

更新日期：2005-05-01 00:00:00

abstract：:Common bile duct perforation causing biliary peritonitis is an unusual entity and a pancreatic calculus causing this perforation is all the more rare, and to our knowledge has not been reported previously. Such an unusual presentation of chronic calcific pancreatitis is herein reported. ...

journal_title：Postgraduate medical journal

authors： Kumar A,Kataria R,Chattopadhyay TK,Karak PK,Tandon RK

更新日期：1992-10-01 00:00:00

abstract：:Two cases of pubic osteomyelitis presenting as a painful hip are reported. In both cases the diagnosis was delayed by the unusual presentation and by the limited radiological investigation. Pubic osteomyelitis is rare in childhood but should be considered in the differential diagnosis of the 'irritable hip'. ...

journal_title：Postgraduate medical journal

authors： Weinberg JR,Berman L,Dootson G,Mitchell R

更新日期：1987-04-01 00:00:00

abstract：:Two cases of patients with ischaemic colitis requiring operative treatment are presented. Both had received a commonly used psychotropic drug in large dosage before the acute episode. Evidence is produced which may link the drugs used with the condition of ischaemic colitis. ...

journal_title：Postgraduate medical journal

authors： Gollock JM,Thomson JP

更新日期：1984-08-01 00:00:00

abstract：PURPOSE:To determine the association between professors' self-perception of mentoring skills and their academic performance. DESIGN:Two hundred and fifteen professors from Imperial College London, the first Academic Health Science Centre (AHSC) in the UK, were surveyed. The instrument adopted was the Mentorship Skills...

journal_title：Postgraduate medical journal

authors： Athanasiou T,Patel V,Garas G,Ashrafian H,Shetty K,Sevdalis N,Panzarasa P,Darzi A,Paroutis S

更新日期：2016-10-01 00:00:00

abstract：:A previously fit man developed psittacosis with marked cerebellar symptoms and signs. He was febrile but not confused, and he responded rapidly to treatment with erythromycin. Even if respiratory symptoms are minimal, psittacosis and other atypical pneumonias should be considered in any patient presenting with fever a...

journal_title：Postgraduate medical journal

authors： Shee CD

更新日期：1988-05-01 00:00:00

abstract：:We describe the occurrence of primary hyperaldosteronism in two sisters. Although this is only the second published report of familial Conn's syndrome, it does have implications for the relatives of patients with Conn's syndrome and these are discussed. ...

journal_title：Postgraduate medical journal

authors： London N,Swales J,Hollinrake K,Bell P,Heagerty A

更新日期：1992-12-01 00:00:00

abstract：:The marked decline in coronary heart disease mortality in the United States since the late 1960s is most likely due in large part to successful efforts at primary prevention, attributable in turn to improved eating habits, better control of blood pressure and a reduction in smoking. Another part of the decline can pro...

journal_title：Postgraduate medical journal

authors： Epstein FH

更新日期：1984-01-01 00:00:00

abstract：:Perforation of the gastrointestinal tract by ingested foreign bodies is rare; the diagnosis of pyogenic liver abscess resulting from such perforations is usually made at post-mortem. We present a case of perforation of the gut, due to an ingested dental plate, with a resultant pyogenic liver abscess, which presented a...

journal_title：Postgraduate medical journal

authors： Shaw PJ,Freeman JG

更新日期：1983-07-01 00:00:00

abstract：:Excess body weight, as defined by the body mass index (BMI), has been associated with several diseases and includes subjects who are overweight (BMI≥25-29.9 kg/m(2)) or obese (BMI≥30 kg/m(2)). Overweight and obesity constitute the fifth leading risk for overall mortality, accounting for at least 2.8 million adult deat...

journal_title：Postgraduate medical journal

authors： Bardou M,Barkun AN,Martel M

更新日期：2013-09-01 00:00:00

abstract：:Amniotic fluid embolism (AFE) associated with disseminated intravascular clotting (DIC) is usually fatal. Such a combination generally occurs at the term of pregnancy or in the immediate postpartum period. A case of AFE with DIC following a hypertonic-saline-induced abortion, is reported. The patient was in the midtri...

journal_title：Postgraduate medical journal

authors： Ballas S,Lessing JB,Michowitz M

更新日期：1983-02-01 00:00:00

abstract：:There has been a dramatic change in the way that resuscitation decisions are made for older hospital inpatients in the UK. In less than 20 years many geriatric medicine wards have moved from an "opt-in" policy (where the default position is not to provide resuscitation) to a position where resuscitation is widely avai...

journal_title：Postgraduate medical journal

authors： Bowker L

更新日期：2009-11-01 00:00:00