Interaction studies and other investigations of the pharmacology of propofol ('Diprivan').

abstract：:Peyronie's disease can cause severe physical and psychological distress. Of 31 cases in this retrospective study, 12 underwent spontaneous improvement in their symptoms which makes the assessment of active treatment in other patients difficult. The indications and limitations of operative approach are discussed. ...

journal_title：Postgraduate medical journal

authors： Odiase VO,Whitaker RH

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Colonoscopy is the best way of imaging the colon with concurrent biopsy and treatment. However it is expensive, requires full bowel preparation, and carries a risk of complications. Flexible sigmoidoscopy is an alternative way to investigate symptoms that raise the suspicion of a lesion of the rectum or left...

journal_title：Postgraduate medical journal

authors： Papagrigoriadis S,Arunkumar I,Koreli A,Corbett WA

更新日期：2004-02-01 00:00:00

abstract：:A case of intrahepatic cholestatic jaundice following warfarin therapy is described. The patient made a complete recovery on withdrawal on the drug. ...

journal_title：Postgraduate medical journal

authors： Jones DB,Makepeace MC,Smith PM

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Current treatment for osteoarthritis (OA) is limited. Many patients with OA of the hand have areas of tender subcutaneous thickening in the forearm and upper scapular region. A pilot study showed an improvement in pain from OA at the first carpometacarpal joint after injection of such areas with 0.5% sodium ...

journal_title：Postgraduate medical journal

authors： Smith AS,Doré CJ,Dennis L,Julius A,Mackworth-Young CG

更新日期：2010-06-01 00:00:00

abstract：:Ganglioneuroblastoma in the spinal region is rare, the treatment of choice being surgical excision. We present a 21 year old male who was diagnosed to have this condition in the dorsolumbar spinal region. The tumour was extending intraspinally and was unresectable. Combination chemotherapy with Adriamycin (doxorubicin...

journal_title：Postgraduate medical journal

authors： Raina V,Kamble R,Tanwar R,Singh SP,Sharma S

更新日期：1993-09-01 00:00:00

abstract：:Erythromelalgia is an unusual condition characterized by attacks of burning pain in the hands and feet with local congestion and increased skin temperature. We report a case of erythromelalgia, with transient hypertension and elevated urinary catecholamines successfully treated by hypnotherapy. Such an association has...

journal_title：Postgraduate medical journal

authors： Chakravarty K,Pharoah PD,Scott DG,Barker S

更新日期：1992-01-01 00:00:00

abstract：:A 72 year old man developed acute myeloblastic leukaemia two years after he had been treated with local curative therapy and chemotherapy for a solitary plasma cytoma of the ilium. ...

journal_title：Postgraduate medical journal

authors： Maharaj D,Dolan G

更新日期：1986-12-01 00:00:00

abstract：:The majority of deaths in COPD are from cardiovascular causes. Several large randomized controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium increase the risk of serious cardiovascular events, including cardiovascular mortality. Tiotropium Respimat is associated with a statistic...

journal_title：Postgraduate medical journal

authors： Singh S,Loke YK,Enright P,Furberg CD

更新日期：2014-04-01 00:00:00

abstract：:The 1994 NACT Wyeth-Ayerst Travelling Fellowship provided the opportunity to compare the education and welfare of pre-registration house officers in the UK with their nearest counterpart in the US residency system. Investment in all aspects of learning was impressive, as was the retention of the central role of the pa...

journal_title：Postgraduate medical journal

authors： Salter R

更新日期：1995-05-01 00:00:00

abstract：:Stroke is a recognised complication of pregnancy, contributing to more than 12% of all maternal deaths. Estimated incidence rates vary considerably from 4.3 to 210 strokes per 100,000 deliveries. Atherosclerosis is rare in young adults, and so other causes of stroke become increasingly likely. Aetiological factors imp...

journal_title：Postgraduate medical journal

authors： Treadwell SD,Thanvi B,Robinson TG

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Previous research has shown that sicker patients are less satisfied with their healthcare, but specific effects of adverse health outcomes have not been investigated. The present study aimed to assess whether patients who experience adverse outcomes, in hospital or after discharge, differ in their evaluation...

journal_title：Postgraduate medical journal

authors： Marang-van de Mheen PJ,van Duijn-Bakker N,Kievit J

更新日期：2008-02-01 00:00:00

abstract：:The Chancellor of the Exchequer's recent announcements to devolve decision making power from Whitehall to 30 English regions provide a challenge to use devolution to deliver more favourable health outcomes. However evaluation of devolved health models internationally is scarce, because it is rarely considered. Evidenc...

journal_title：Postgraduate medical journal

authors： Doyle Y,Johnstone P

更新日期：2016-05-01 00:00:00

abstract：:Two patients with a rise in cardiac troponin T (cTnT) concentrations during the course of lobar pneumonia, without any evidence of acute coronary syndrome or renal failure, are presented. The increase in cTnT concentration is considered a highly sensitive marker of cardiac injury, although it may also rise in other co...

journal_title：Postgraduate medical journal

authors： Weinberg I,Cukierman T,Chajek-Shaul T

更新日期：2002-04-01 00:00:00

abstract：:Head injury from physical abuse is unfortunately a common occurrence in our society. It is a major cause of mortality and long-term physical and psychological disability in children. Diagnosis of non-accidental head injury may be difficult, as most infants present with non-specific clinical findings and without extern...

journal_title：Postgraduate medical journal

authors： Rajaram S,Batty R,Rittey CD,Griffiths PD,Connolly DJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:For gastroenterology, The Royal College of Physicians reiterates the common practice of two to three consultant ward rounds per week. The Royal Bolton Hospital NHS Foundation Trust operated a 26-bed gastroenterology ward, covered by two consultants at any one time. A traditional system of two ward rounds per...

journal_title：Postgraduate medical journal

authors： Singh S,Lipscomb G,Padmakumar K,Ramamoorthy R,Ryan S,Bates V,Crompton S,Dermody E,Moriarty K

更新日期：2012-10-01 00:00:00

abstract：:An 84 year old woman who was a heavy smoker presented with clinical features suggestive of acute exacerbation of chronic obstructive lung disease complicated by left ventricular failure. She responded poorly to treatment and then the finding of stridor, only when she was in the supine position, led to the diagnosis of...

journal_title：Postgraduate medical journal

authors： Antonios TF,Singer DR,Millard FJ,Wilson AG,MacGregor GA

更新日期：1994-12-01 00:00:00

abstract：:This article reviews the unique pharmacological properties of methadone and outlines its appropriate clinical application, with focus upon its use in the treatment of chronic pain. Although methadone is most widely known for its use in the treatment of opioid dependence, methadone also provides effective analgesia. Pa...

journal_title：Postgraduate medical journal

authors： Brown R,Kraus C,Fleming M,Reddy S

更新日期：2004-11-01 00:00:00

abstract：:Between 1975 and 1982 in 2 centres in Glasgow, 53 previously untreated patients with aggressive non-Hodgkin's lymphomas received chemotherapy consisting of one of the following regimens-CVP, MOPP, CHOP or BACOP. Twenty nine patients (55%) entered complete remission (CR), 20 (38%) had partial remission (PR) and 4 (7%) ...

journal_title：Postgraduate medical journal

authors： Cunningham D,Hepplestone A,Gilchrist NL,Dagg JH,Evans IL,Soukop M

更新日期：1987-01-01 00:00:00

abstract：:Up to one fifth of patients who present to specialist clinics with seizures do not have epilepsy. The majority of such patients suffer from psychologically mediated episodes; dissociative seizures, often referred to as "non-epileptic seizures". This paper describes the diagnostic evaluation of seizure disorders, inclu...

journal_title：Postgraduate medical journal

authors： Mellers JD

更新日期：2005-08-01 00:00:00

abstract：:Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases). The results were compared with those obtained in 18 controls (hospital out-patients). There were no differences in...

journal_title：Postgraduate medical journal

authors： Taylor RG,Crisp AJ,Hoffbrand BI,Maguire A,Jacobs HS

更新日期：1981-07-01 00:00:00

abstract：:A patient with occult pancreatic carcinoma associated with recurrent acute pancreatitis is reported. Endoscopic retrograde cholangiopancreatography after the first attack was normal, the diagnosis being made at repeat examination 10 months later. ...

journal_title：Postgraduate medical journal

authors： Wilson C,Imrie CW

更新日期：1986-08-01 00:00:00

abstract：:Primary choriocarcinoma of the ovary arising, presumably, from a germ cell is extremely rare. The patient, a 16 year old girl who presented with dysuria and frequency of micturition developed fatal haemoperitoneum due to rupture of a pure primary nongestational ovarian choriocarcinoma. ...

journal_title：Postgraduate medical journal

authors： Raju GC,Woo J,Marchack D,Naraynsingh V

更新日期：1985-08-01 00:00:00

abstract：:A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...

journal_title：Postgraduate medical journal

authors： Clague HW,Warren B,Krasner N

更新日期：1984-09-01 00:00:00

abstract：:Chlorpromazine-induced agranulocytosis is an uncommon disorder associated with a high frequency of fatality. We describe two patients with chlorpromazine-induced granulocytosis in whom granulocyte colony stimulating factor (G-CSF) administration enhanced the speed of neutrophil recovery. No toxicity was noted with G-C...

journal_title：Postgraduate medical journal

authors： Kendra JR,Rugman FP,Flaherty TA,Myers A,Horsfield N,Barton A,Russell L

更新日期：1993-11-01 00:00:00

abstract：:The Mirizzi syndrome is an unusual presentation of gallstones which occurs when a gallstone becomes impacted in either Hartmann's pouch of the gallbladder or the cystic duct, causing obstruction of the common hepatic duct by extrinsic compression. The diagnosis of this syndrome is of importance because surgery in its ...

journal_title：Postgraduate medical journal

authors： Pemberton M,Wells AD

更新日期：1997-08-01 00:00:00

abstract：:Fibrosing colonopathy is a recently described complication of cystic fibrosis, of unknown aetiology but possibly related to treatment with high-dose pancreatic enzyme supplements. We have used a whole gut perfusion technique to study subclinical gut inflammation in cystic fibrosis patients; concentrations of haemoglob...

journal_title：Postgraduate medical journal

authors： Croft NM,Marshall TG,Ferguson A

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVES:Appropriate assessment of community-acquired pneumonia (CAP) allows accurate severity scoring and hence optimal management, leading to reduced morbidity and mortality. British Thoracic Society (BTS) guidelines provide an appropriate score. Adherence to BTS guidelines was assessed in our medical assessment un...

journal_title：Postgraduate medical journal

authors： Collini P,Beadsworth M,Anson J,Neal T,Burnham P,Deegan P,Beeching N,Miller A

更新日期：2007-08-01 00:00:00

abstract：:Pregnancy is a time of great maternal physiological and metabolic changes. This affects the biochemical and haematological parameters used in the assessment of liver disease, and it is important to appreciate the different reference ranges in pregnancy to facilitate recognition of liver disorders in pregnancy. Due to ...

journal_title：Postgraduate medical journal

authors： Mackillop L,Williamson C

更新日期：2010-03-01 00:00:00

abstract：:Important implications for the recognition of iron deficiency anaemia include diagnosis and correction of underlying causes, most of which are identifiable, in the older patient, by means of conventional upper gastrointestinal endoscopy, and by colonoscopy. The aetiological search may, however, have to be widened to i...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：2000-04-01 00:00:00

abstract：:The risk of developing an overt malignancy after an isolated deep venous thrombosis (DVT) is poorly documented. We therefore reviewed a series of patients in whom a solitary idiopathic DVT had been proven by venography at least 12 months earlier. No patient had developed a malignancy at follow-up. However, decreased f...

journal_title：Postgraduate medical journal

authors： O'Connor NT,Cederholm-Williams SA,Fletcher EW,Allington M,Sharp AA

更新日期：1984-04-01 00:00:00