How much can elderly patients tell us about their medications?

abstract：:The insulin resistance/metabolic syndrome is characterised by the variable coexistence of hyperinsulinaemia, obesity, dyslipidaemia, and hypertension. The pathogenesis of the syndrome has multiple origins, but obesity and sedentary lifestyle coupled with diet and still largely unknown genetic factors clearly interact ...

journal_title：Postgraduate medical journal

authors： Kolovou GD,Anagnostopoulou KK,Cokkinos DV

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The International Diabetes Attitudes, Wishes, and Needs (DAWN) programmes have shown the existence of a critical gap in self management support and access to the support system. This study aims to evaluate the effectiveness of the diabetes mellitus (DM) self management programme, with partnership between gen...

journal_title：Postgraduate medical journal

authors： Lee A,Siu CF,Leung KT,Lau LC,Chan CC,Wong KK

更新日期：2011-10-01 00:00:00

abstract：:A child with the isolated anomaly of azygos continuation of the inferior vena cava is presented. The interest of this abnormality lies in its detection as a mediastinal mass on the chest radiograph. Computed tomography with intravenous contrast enhancement is the method of choice to diagnose this venous anomaly. Aware...

journal_title：Postgraduate medical journal

authors： Beedie RJ,Yeo W,Morcos SK

更新日期：1989-04-01 00:00:00

abstract：:Patients with coronary atherosclerosis present with angina, myocardial infarction and sudden death, most often caused by atherosclerotic stenosis complicated by spasm and/or occlusive thrombosis. All of these events have been shown to exhibit similar diurnal rhythms, with a peak incidence in the morning after waking a...

journal_title：Postgraduate medical journal

authors： Selwyn AP,Raby K,Vita JA,Ganz P,Yeung A

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The survival of whites who have been treated for pernicious anaemia (PA) is unaffected, apart from incurring a greater risk of gastric cancers. The long term outcome of PA in Chinese is unknown. METHODS:A hospital based prospective longitudinal study of Chinese PA patients was conducted. Patients with known...

journal_title：Postgraduate medical journal

authors： Chan JC,Liu HS,Kho BC,Lau TK,Li VL,Chan FH,Leong IS,Pang HK,Lee CK,Liang YS

更新日期：2008-12-01 00:00:00

abstract：:Toxicity to digoxin was monitored in 437 consecutive recipients in a comprehensive drug surveillance programme, Adverse reactions developed in 19.5% and, in contrast to previous reports, were generally of a relatively benign nature. There were no drug-related deaths, but patients with adverse reactions spent longer in...

journal_title：Postgraduate medical journal

authors： Henry DA,Lowe JM,Lawson DA,Whiting B

更新日期：1981-06-01 00:00:00

abstract：:Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia...

journal_title：Postgraduate medical journal

authors： Braun GS,Horster S,Wagner KS,Ihrler S,Schmid H

更新日期：2007-02-01 00:00:00

abstract：:Healthcare workers have a high risk of occupational exposure, more so in developing countries, with high incidence of blood borne diseases and prevalence of unsafe practices. Among the various blood borne diseases, the most common and important ones are HIV infection, hepatitis B, and hepatitis C. Most of the occupati...

journal_title：Postgraduate medical journal

authors： Varghese GM,Abraham OC,Mathai D

更新日期：2003-06-01 00:00:00

abstract：:The morphological features of endomyocardial fibrosis and Löffler's endocarditis are described. Sixteen cases of the chronic stage of Löffler's endocarditis were compared with pathological material of thirty-two patients with endomyocardial fibrosis. No morphological differences were noted. It is suggested that endomy...

journal_title：Postgraduate medical journal

authors： Olsen EG

更新日期：1977-09-01 00:00:00

abstract：:Splenic peliosis was identified at necropsy in a 62-year-old woman receiving continuous ambulatory peritoneal dialysis for end-stage renal failure, and erythropoietin therapy for uraemia and anaemia. The immediate cause of death was arrhythmia related to ischaemic heart disease, following an episode of intramuscular h...

journal_title：Postgraduate medical journal

authors： Lam KY,Chan AC,Chan TM

更新日期：1995-08-01 00:00:00

abstract：:In a cross-over study, 10 healthy adult volunteers received 1 g cefaclor and 1 g cephalexin orally 1 hour after a standard breakfast. Serum levels of cefaclor rose somewhat faster and were higher than those of cephalexin in the first 60 minutes. At the end of the second hour the serum concentration of cephalexin was 5...

journal_title：Postgraduate medical journal

authors： Simon C,Gatzemeier U

更新日期：1979-01-01 00:00:00

abstract：:Synovial plicae are normal anatomical structures of the knee that may become symptomatic. MRI is an established technique for evaluating the anatomy of the knee, and it is a valuable tool for detecting plicae because of its high resolution resulting in increased tissue characterisation. At MRI, knee plicae appear as l...

journal_title：Postgraduate medical journal

authors： Vassiou K,Vlychou M,Zibis A,Nikolopoulou A,Fezoulidis I,Arvanitis D

更新日期：2015-01-01 00:00:00

abstract：:Cystinuria is an autosomal recessive disorder in renal tubular and intestinal transport of dibasic amino acids, which results in increased urinary excretion of cystine, ornithine, lysine and arginine. It affects 1 in 20 000 people and is caused by a defect in the rBAT gene on chromosome 2. Development of urinary tract...

journal_title：Postgraduate medical journal

authors： Ahmed K,Dasgupta P,Khan MS

更新日期：2006-12-01 00:00:00

abstract：:Fistulous communications of the uterus are relatively unknown. We report in this paper the first case to our knowledge of uterocutaneous fistula which developed following a septic abortion induced by introduction of Laminaria tent into the uterus. ...

journal_title：Postgraduate medical journal

authors： Gupta SK,Shukla VK,Varma DN,Roy SK

更新日期：1993-10-01 00:00:00

abstract：:The clinical features, treatment and survival of 36 patients with microscopic polyarteritis diagnosed between 1957-1988 have been reviewed. All had a focal segmental necrotizing glomerulonephritis on renal biopsy with evidence of a small vessel vasculitis. Most had a prodromal illness of less than 1 month. Severity of...

journal_title：Postgraduate medical journal

authors： Rodgers H,Guthrie JA,Brownjohn AM,Turney JH

更新日期：1989-08-01 00:00:00

abstract：:Patients with acquired von Willebrand disease may present with severe bleeding, which is usually difficult to manage. Adequate haemostasis in acquired von Willebrand disease may be achieved with the infusion of factor VIII/von Willebrand factor concentrates or with the administration of desmopressin. We report a case ...

journal_title：Postgraduate medical journal

authors： Van Genderen PJ,Papatsonis DN,Michiels JJ,Wielenga JJ,Stibbe J,Huikeshoven FJ

更新日期：1994-12-01 00:00:00

abstract：:Serum lysozyme (muramidase) estimation is a simple, convenient and useful laboratory investigation. A review of the literature shows that lysozyme has been implicated as an aetiological factor in various disorders, and credited with being a prognostic indicator in acute myeloid leukaemia, but these promises have not b...

journal_title：Postgraduate medical journal

authors： Mir MA

更新日期：1977-05-01 00:00:00

abstract：:Altogether 42 million people worldwide have been infected with HIV, and 12 million have died over the last 20 years. Effective antiretroviral therapy has lead to sustained HIV viral suppression and immunological recovery in patients who have been infected with the virus. The incidence of AIDS has declined in the Weste...

journal_title：Postgraduate medical journal

authors： Thaker HK,Snow MH

更新日期：2003-01-01 00:00:00

abstract：:We report a case of persistent chorea as a manifestation of thyrotoxicosis. The chorea was severe and persisted after the patient was rendered euthyroid. Dopamine antagonists only partially suppressed the involuntary movements during the first few months. It was eventually controlled with haloperidol, but whenever she...

journal_title：Postgraduate medical journal

authors： Javaid A,Hilton DD

更新日期：1988-10-01 00:00:00

abstract：INTRODUCTION:Potentially inappropriate medication (PIM) prescribing is a global problem. Limited data are available on the prevalence of PIMs in elderly patients with chronic kidney disease (CKD). We examined the PIM prevalence in elderly patients with CKD, the most common drugs implicated and the levels of polypharmac...

journal_title：Postgraduate medical journal

authors： Jones SA,Bhandari S

更新日期：2013-05-01 00:00:00

abstract：:Postgraduate medical education (PME) quality assurance at Health Education England (HEE) currently relies upon survey data. As no one metric can reflect all aspects of training, and each has its limitations, additional metrics should be explored. At HEE (West Midlands), we explored the use of learner outcomes, special...

journal_title：Postgraduate medical journal

authors： Pinnell J,Tranter A,Cooper S,Whallett A

更新日期：2020-11-12 00:00:00

abstract：:A multi-centre double-blind randomized study is reported in which the effect on mortality of oral disopyramide (300 mg loading dose, then 100 mg qds) was compared with placebo in 1985 patients entering hospital with suspected acute myocardial infarction. Treatment was commenced with 24 hr of onset of symptoms (mean ti...

journal_title：Postgraduate medical journal

authors：

更新日期：1984-02-01 00:00:00

abstract：:Muscarinic receptors are present on several different cells in lung and are predominantly involved in bronchoconstriction and mucus secretion. Muscarinic receptor activation leads to breakdown of phosphoinositides in airway smooth muscle cell membranes, which leads to intracellular calcium release and contraction. Mus...

journal_title：Postgraduate medical journal

authors： Barnes PJ

更新日期：1987-01-01 00:00:00

abstract：:Verrucous carcinoma is a rare skin malignancy of squamous cell origin. It is characterised by negligible cellular atypia and a low mitotic rate. These are reflected in slow locally invasive behaviour and very infrequent metastatic spread. The tumour is also recognised in oral and anogenital sites. Cutaneous lesions pr...

journal_title：Postgraduate medical journal

authors： Munro NA,Smith C,Purushotham AD

更新日期：1999-11-01 00:00:00

abstract：:A 60 year old woman with computed tomographic-verified bilateral thalamic infarction is described. She demonstrated downward gaze paralysis, amnesia and hypersomnolence. On the functional level such tasks as walking and eating were disconcerting. Although there have been only a few reports of the complete triad it may...

journal_title：Postgraduate medical journal

authors： Nagaratnam N,Ghougassian DF,Mugridge V

更新日期：1989-11-01 00:00:00

abstract：:Haemorrhage of small bowel origin may prove to be a clinical and diagnostic challenge, particularly when the bleeding is massive and continuous. Such a case is described where the source of blood loss was a jejunal vascular abnormality. ...

journal_title：Postgraduate medical journal

authors： Saunders MP

更新日期：1991-07-01 00:00:00

abstract：:Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing disti...

journal_title：Postgraduate medical journal

authors： Carder PJ,Gouldesbrough DR

更新日期：1993-05-01 00:00:00

abstract：:Both acute myocardial infarction and reperfusion therapy with thrombolytic agents may be associated with bradyarrhythmias, and there may be a case for 'prophylactic' insertion of a temporary pacing wire in selected patients. We describe 4 patients in whom clinical decisions had to be made concerning the appropriatenes...

journal_title：Postgraduate medical journal

authors： Lim CW,Bennie MJ,Lim R

更新日期：1991-07-01 00:00:00

abstract：:Primary gastric lymphoma is a rare tumour. It is thought that low grade gastric mucosa associated lymphoid tissue lymphoma has not been previously reported to occur in a patient with gastrojejunostomy. This report describes such a case. The patient presented with bleeding from non-healing stomal ulcers. The ulcers hea...

journal_title：Postgraduate medical journal

authors： Misra SP,Misra V,Dwivedi M

更新日期：2005-02-01 00:00:00

abstract：:The clinical syndrome of heart failure has been investigated so extensively that it may now almost be regarded as a metabolic disorder. Although an initial insult reduces cardiac pump efficacy, the resultant physiological response culminates in complex neurohormonal dysfunction. This has created confusion and prevente...

journal_title：Postgraduate medical journal

authors： Wright DJ,Tan LB

更新日期：1999-08-01 00:00:00