Macrocytic anaemia due to copper deficiency in a patient with late onset hypogammaglobulinaemia.

abstract：:The aortic root links the left ventricle and ascending aorta and functions as a support structure for the aortic valve. It can be affected by a variety of congenital and acquired conditions, some of which are potentially life threatening. Echocardiography and cardiac magnetic resonance imaging are established non-inva...

journal_title：Postgraduate medical journal

authors： Vargas HA,Hoey ET,Gopalan D,Agrawal SK,Screaton NJ,Gulati GS

更新日期：2009-07-01 00:00:00

abstract：:A 5 year old female child presented with a psoas haematoma as the first manifestation of haemophilia B. Molecular genetic studies were performed to investigate the inheritance of the disorder and the mechanisms by which females may express the haemophilia B phenotype are discussed. ...

journal_title：Postgraduate medical journal

authors： Palmer S,Standen GR,Yates P,Oakhill A

更新日期：1994-11-01 00:00:00

abstract：:Oral administration of 1 g of acetazolamide to 8 normal subjects studied at sea level and in normoxia caused an acute increase in cerebral blood flow (CBF). During the subsequent prolonged oral treatment with 1 g of acetazolamide daily, CBF returned to normal within 2 days. The alveolar CO2 tension decreased gradually...

journal_title：Postgraduate medical journal

authors： Lassen NA,Friberg L,Kastrup J,Rizzi D,Jensen JJ

更新日期：1987-03-01 00:00:00

abstract：:In 114 patients (52 males and 62 females) with long-standing pernicious anaemia, hypoferritinaemia was found in 27 (23.7%) and hypochromic microcytic anaemia in 19 (16.6%). Our findings indicate that iron deficiency is a common yet neglected complication of long-standing pernicious anaemia and warrants greater diagnos...

journal_title：Postgraduate medical journal

authors： Atrah HI,Davidson RJ

更新日期：1988-02-01 00:00:00

abstract：:A patient is described who developed acute peripheral neuropathy of Guillain-Barré type occurring shortly after commencement of captopril for moderately severe hypertension and resolving after discontinuation of the drug. ...

journal_title：Postgraduate medical journal

authors： Chakraborty TK,Ruddell WS

更新日期：1987-03-01 00:00:00

abstract：:Fungal infections of the central nervous system present a considerable challenge to available chemotherapy and other forms of treatment. The particular difficulties are discussed here, after an account of the fungi involved and their sensitivity to antifungal agents. Cryptococcal, coccidioidal and candidal infections ...

journal_title：Postgraduate medical journal

authors： Speller DC

更新日期：1979-09-01 00:00:00

abstract：:Lymphocyte adenosine deaminase (L-ADA) activity, a measure of lymphocyte activity, was estimated in 10 healthy controls and 30 patients with typhoid fever (20 uncomplicated and 10 complicated) at the time of admission, at onset of complications and weekly until recovery. Mean L-ADA activity in healthy controls was 20....

journal_title：Postgraduate medical journal

authors： Khosla SN,Kumar D,Singh V

更新日期：1992-04-01 00:00:00

abstract：:The inflammatory neuropathies are a large diverse group of immune-mediated neuropathies that are amenable to treatment and may be reversible. Their accurate diagnosis is essential for informing the patient of the likely course and prognosis of the disease, informing the treating physician of the appropriate therapy an...

journal_title：Postgraduate medical journal

authors： Lunn MP,Willison HJ

更新日期：2009-08-01 00:00:00

abstract：:The effects of infusions of prostaglandin E1 (PGE1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. Thirteen patients with atherosclerotic vascular disease received intravenous PGE1 25 mg/kg/min for 6 hours daily for 5 days. Prostaglandin E1 had no effect on platelet uptake at athero...

journal_title：Postgraduate medical journal

authors： Sinzinger H,O'Grady J,Fitscha P

更新日期：1987-04-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world, and has a wide geographical variation. Eighty per cent of HCC is attributed to hepatitis B virus (HBV). The predominant carcinogenic mechanism of HBV associated HCC is through the process of liver cirrhosis, but direct oncogenic effects of HB...

journal_title：Postgraduate medical journal

authors： Park NH,Song IH,Chung YH

更新日期：2006-08-01 00:00:00

abstract：:Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary d...

journal_title：Postgraduate medical journal

authors： Lozewicz S,Morris G,Garbett N,Browse N,Slavin B,Cole P

更新日期：1988-01-01 00:00:00

abstract：:A case of gonococcal urethritis with bilateral tysonitis is discussed. The patient was treated successfully with oral tetracycline 500 mg 6 hourly for 10 days, with a complete resolution. ...

journal_title：Postgraduate medical journal

authors： Abdul Gaffoor PM

更新日期：1986-09-01 00:00:00

abstract：:Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased ris...

journal_title：Postgraduate medical journal

authors： Raj A,Mayberry JF,Podas T

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To assess parent preferences for utilisation of a parent-focused, telephone-based coaching service, or 'FITLINE,' to prevent or manage childhood obesity. METHODS:A cross-sectional survey of parents of children aged 2-12 years was conducted at a paediatric practice in Greater Boston, Massachusetts, USA, betwe...

journal_title：Postgraduate medical journal

authors： Blaine RE,Pbert L,Geller AC,Powers EM,Mitchell K

更新日期：2015-04-01 00:00:00

abstract：:Two patients with nephrotic syndrome developed fatal fulminant hepatitis B following withdrawal of prednisolone or cyclophosphamide. Immunosuppressive therapy probably enhanced hepatitis B virus (HBV) replication and widespread infection of hepatocytes; its withdrawal permitted a return of immune competence resulting ...

journal_title：Postgraduate medical journal

authors： Onwubalili JK

更新日期：1988-04-01 00:00:00

abstract：:A 46 year old Nigerian man presented with a four week history of progressive bilateral visual loss. He had been unwell, with weight loss, fever, and night sweats for six months. Dilated fundoscopy revealed macular haemorrhages and diffuse Roth's spots. The patient was found to be severely anaemic and a bone marrow asp...

journal_title：Postgraduate medical journal

authors： Vose MJ,Charles SJ

更新日期：2003-02-01 00:00:00

abstract：:Paradoxical vocal cord motion disorder (PVCM), also called vocal cord dysfunction, is an important differential diagnosis for asthma. The disorder is often misdiagnosed as asthma leading to unnecessary drug use, very high medical utilisation and occasionally tracheal intubation or tracheostomy. Laryngoscopy is the gol...

journal_title：Postgraduate medical journal

authors： Ibrahim WH,Gheriani HA,Almohamed AA,Raza T

更新日期：2007-03-01 00:00:00

abstract：:Herniation of a thoracic disc in an acromegalic giant is reported. Degenerative changes in the spine in association with dorsal kyphosis, and the additional strain, resulted in the disc prolapse. ...

journal_title：Postgraduate medical journal

authors： Chhang WH,Sharma BS,Dash RJ,Kak VK

更新日期：1989-07-01 00:00:00

abstract：:Pneumonia due to Mycoplasma pneumoniae is common, but it is rarely life-threatening. A case is reported in a previously healthy adult whose illness was severe enough to require treatment with intermittent positive pressure ventilation (IPPV) for 14 days and which resolved after treatment with corticosteroids. ...

journal_title：Postgraduate medical journal

authors： McGonigle R,Wagstaff JK

更新日期：1980-09-01 00:00:00

abstract：:We report the development of synchronous bilateral carpal tunnel syndrome in a woman with metastatic colorectal cancer, undergoing treatment with recombinant interleukin 2. A carpal tunnel decompression was carried out on the hand which was more severely affected, with a gradual recovery in median nerve function. To t...

journal_title：Postgraduate medical journal

authors： Heys SD,Mills KL,Eremin O

更新日期：1992-07-01 00:00:00

abstract：:Cardiovascular complications of cirrhosis include cardiac dysfunction and abnormalities in the central, splanchnic and peripheral circulation, and haemodynamic changes caused by humoral and nervous dysregulation. Cirrhotic cardiomyopathy implies systolic and diastolic dysfunction and electrophysiological abnormalities...

journal_title：Postgraduate medical journal

authors： Møller S,Henriksen JH

更新日期：2009-01-01 00:00:00

abstract：:We report three cases of a distinctive palmar-plantar erythema associated with the treatment of non-Hodgkin's lymphoma and acute myeloid leukaemia. The rash is characterized by a painful, sharply demarcated, intense erythema of the palms and/or soles followed by bulla formation, desquamation and healing. The eruption ...

journal_title：Postgraduate medical journal

authors： Pagliuca A,Kaczmarski R,Mufti GJ

更新日期：1990-03-01 00:00:00

abstract：:For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare professionals and their patients, helping to build a relationship of trust. But beware the fal...

journal_title：Postgraduate medical journal

authors： Beamish AJ,Foster JJ,Edwards H,Olbers T

更新日期：2019-02-01 00:00:00

abstract：:The nature of rehabilitation medicine is outlined in terms of its objectives, its methods, the patient groups which it seeks to help and its relationships to other specialties. Some major advances of recent years are discussed, such as the development of the impairment/disability/handicap framework. With particular em...

journal_title：Postgraduate medical journal

authors： Cozens JA,Chamberlain MA

更新日期：1995-11-01 00:00:00

abstract：:A previously undescribed type of congenital abdominal wall hernia is described. Presentation was with the symptoms and signs of subacute large bowel obstruction. The diagnosis was suggested by barium enema and confirmed at laparotomy. ...

journal_title：Postgraduate medical journal

authors： Siriwardena AK

更新日期：1989-02-01 00:00:00

abstract：:I report a case of a large liver abscess causing a severe debilitating condition in which the diagnosis was delayed by several weeks following two normal ultrasound scans at days 5 and 19 of the illness. Up to one in four cases of liver abscess can be missed on ultrasound. A high degree of clinical suspicion must be m...

journal_title：Postgraduate medical journal

authors： Bunney RG

更新日期：1988-05-01 00:00:00

abstract：:A 28 year old female patient with Cushing's syndrome due to an adrenal adenoma also suffered from recurrent urinary infections (proteus), tonsillitis (streptococcus), permanent candidiasis and perimandibular abscess (Staphylococcus pyogenes). Suppression of cellular and humoral immunity was confirmed by in vitro tests...

journal_title：Postgraduate medical journal

authors： Würzburger MI,Prelević GM,Brkić SD,Vucković S,Pendić B

更新日期：1986-07-01 00:00:00

abstract：PURPOSE OF THE STUDY:Grit is characterised by the ability to persevere during difficulties and maintain a sustained effort over an extended period of time. Throughout their careers, doctors will experience many periods of stress and difficulty. This may result in burnout, defined by the presence of exhaustion and disen...

journal_title：Postgraduate medical journal

authors： Halliday L,Walker A,Vig S,Hines J,Brecknell J

更新日期：2017-07-01 00:00:00

abstract：:We report the case of a young man with Fusobacterium necrophorum meningitis who developed bilateral carotid artery stenosis associated with thrombosis of the cavernous sinuses. Intraluminal clot was present in the region of the stenoses for which he was anticoagulated. The clinical presentation, problems with diagnosi...

journal_title：Postgraduate medical journal

authors： Jones TH,Bergvall V,Bradshaw JP

更新日期：1990-09-01 00:00:00

abstract：CONTEXT:In Sweden, patient malpractice claims are handled administratively and compensated if an independent physician review confirms patient injury resulting from medical error. Full access to all malpractice claims and hospital discharge data for the country provided a unique opportunity to assess the validity of pa...

journal_title：Postgraduate medical journal

authors： Pukk-Härenstam K,Ask J,Brommels M,Thor J,Penaloza RV,Gaffney FA

更新日期：2009-02-01 00:00:00