Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.

abstract：:Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the distal nephron. Oral doses of 250 mg given to normal human volunteers provided peak blood levels of 10--11 micrograms/ml at 3--4 hours after administration. Approximately 40% of the dose was reco...

journal_title：Postgraduate medical journal

authors： Dubb JW,Stote RM,Maass AR,Hwang BV,Familiar RG,Alexander F

更新日期：1979-01-01 00:00:00

abstract：:Various tumours, in particular lymphomas, have been reported in association with azathioprine treatment, both after renal transplantation and in other conditions. A case is reported here of acute myeloid leukaemia associated with azathioprine therapy for rheumatoid arthritis, and this is now the third case reported in...

journal_title：Postgraduate medical journal

authors： Gilmore IT,Holden G,Rodan KS

更新日期：1977-03-01 00:00:00

abstract：:The nature of rehabilitation medicine is outlined in terms of its objectives, its methods, the patient groups which it seeks to help and its relationships to other specialties. Some major advances of recent years are discussed, such as the development of the impairment/disability/handicap framework. With particular em...

journal_title：Postgraduate medical journal

authors： Cozens JA,Chamberlain MA

更新日期：1995-11-01 00:00:00

abstract：:Clinical, endocrinological and computed tomographic features of three patients with unusual manifestations or complications of craniofacial involvement of fibrous dysplasia are presented. One patient with polyostotic fibrous dysplasia presented in late pregnancy with acute onset of bilateral optic nerve compression an...

journal_title：Postgraduate medical journal

authors： Daly BD,Chow CC,Cockram CS

更新日期：1994-01-01 00:00:00

abstract：:The gastric acid response and the buffer capacity of the stomach were measured in 30 control subjects and 22 duodenal ulcer patients in response to a masticatory (solid) and a non-masticatory (homogenized) meal having the same chemical composition. The peak acid output values were equal after a masticatory and after a...

journal_title：Postgraduate medical journal

authors： Dubey P,Nundy S

更新日期：1984-04-01 00:00:00

abstract：:Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials usin...

journal_title：Postgraduate medical journal

authors： Chehab OM,Dakik HA

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the reasons why primary care doctors undertake postgraduate diploma studies in a mixed private/public Asian setting. METHODS:Twenty four past or current postgraduate diploma students of the family medicine unit (FMU) of the University of Hong Kong participated in three fo...

journal_title：Postgraduate medical journal

authors： Lam TP,Lam KF,Tse EY

更新日期：2006-06-01 00:00:00

abstract：:The new formulation of propofol appears to be approximately equipotent to the previous formulation when used as an infusion to supplement nitrous oxide anaesthesia in patients premedicated with morphine. Preliminary haemodynamic studies indicate that the emulsion formulation causes more arterial hypotension than the o...

journal_title：Postgraduate medical journal

authors： Coates DP,Prys-Roberts C,Spelina KR,Monk CR,Norley I

更新日期：1985-01-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a significant morbidity and mortality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache, and dyspnoea. Older subjects may present without the typical febrile response. Common lab...

journal_title：Postgraduate medical journal

authors： Hui DS,Chan MC,Wu AK,Ng PC

更新日期：2004-07-01 00:00:00

abstract：:Eight patients with steroid-sensitive nephrotic syndrome which frequently relapsed despite cyclophosphamide treatment were given cyclosporin A (7.5 mg/kg/day to 10 mg/kg/day) for 8 to 12 weeks. Six had minimal change glomerulonephritis and two had focal segmental glomerulonephritis. Cyclosporin A was given to 5 patien...

journal_title：Postgraduate medical journal

authors： Chan MK,Cheng IK

更新日期：1987-09-01 00:00:00

abstract：:Fasting plasma and urinary calcium and urinary hydroxyproline are known to rise at the menopause, reflecting increased bone resorption. Oestradiol valerate and cyclic oestradiol valerate/DL-norgestrel are shown to reduce this evidence of increased bone loss. It is concluded that these preparations will be effective in...

journal_title：Postgraduate medical journal

authors： Crilly RG,Marshall DH,Nordin BE

更新日期：1978-01-01 00:00:00

abstract：:Important implications for the recognition of iron deficiency anaemia include diagnosis and correction of underlying causes, most of which are identifiable, in the older patient, by means of conventional upper gastrointestinal endoscopy, and by colonoscopy. The aetiological search may, however, have to be widened to i...

journal_title：Postgraduate medical journal

authors： Jolobe OM

更新日期：2000-04-01 00:00:00

abstract：:The Wolff-Parkinson-White syndrome can rarely present with pre-excited atrial fibrillation. In this condition the short refractory period of the accessory pathway can lead to rapid atrioventricular conduction. There is then a danger that at high heart rates the irregular broad complex tachycardia that results can dete...

journal_title：Postgraduate medical journal

authors： Adlam D,Azeem T

更新日期：2003-05-01 00:00:00

abstract：:In 40 hypertensive patients continuous ECG recording was done before and after 30 days treatment with indapamide 2.5 mg. There was no change in heart rate. In addition, the incidence of extrasystoles was not changed in patients in whom the ECG was normal before treatment (30 cases) or in 8 of the 10 patients who had a...

journal_title：Postgraduate medical journal

authors： Haiat R,Lellouch A,Lanfranchi J,Witchitz S

更新日期：1981-01-01 00:00:00

abstract：:A 44 year old female presented with a subacute myelopathy in association with pelvic venous thrombosis. It is inferred from the temporal relationship of these events that the patient suffered a subacute spinal venous infarction. This is discussed along with the aetiology, anatomical distribution and management of the ...

journal_title：Postgraduate medical journal

authors： Clarke CE,Cumming WJ

更新日期：1987-08-01 00:00:00

abstract：:104 consecutive patients with upper gastrointestinal bleeding admitted to a district general hospital over a period of 20 months were considered for laser photocoagulation. 58 patients were found to have peptic ulcers, of which 42 had stigmata of recent haemorrhage accessible to laser photocoagulation. 17 were treated...

journal_title：Postgraduate medical journal

authors： Homer AC,Powell S,Vicary FR

更新日期：1985-01-01 00:00:00

abstract：:The incidence, aetiology and possible inheritance of duodenal diverticula remain controversial. These aspects are discussed through the presentation of a family, in which duodenal diverticula occurred in a man and his two sons. To the best of our knowledge, this is the first such family documented in the medical liter...

journal_title：Postgraduate medical journal

authors： Sternberg A,Deutsch AA,Kott I,Reiss R

更新日期：1984-07-01 00:00:00

abstract：:Although the relationship between group A streptococcal upper respiratory tract infection and the development of acute rheumatic fever has been known for many years, the pathogenetic mechanism(s) have never been defined. Thus, the mechanism of damage to the valves and to the myocardium in patients with rheumatic fever...

journal_title：Postgraduate medical journal

authors： Kaplan EL

更新日期：1992-01-01 00:00:00

abstract：:The interpretation of gastrin release is confused because of variation in the technique of the radioimmuoassay of gastrin, the lack of a standard stimulus for the release of gastrin and diversity in the method used to express the results. These problems have been analysed (a) by examining the cross-reactivity of three...

journal_title：Postgraduate medical journal

authors： Russel RC,Bloom SR,Fielding LP,Bryant MG

更新日期：1976-10-01 00:00:00

abstract：:Thiazide diuretics used alone to treat hypertension can cause hypokalaemia in a substantial proportion of patients. The possibility exists that any benefit of reducing high blood pressure by such treatment may be offset by an increased mortality due to arrhythmias initiated by hypokalaemia. ...

journal_title：Postgraduate medical journal

authors： Poole-Wilson PA

更新日期：1983-01-01 00:00:00

abstract：:Previous reports have demonstrated that patients with hypertrophic cardiomyopathy (HCM) have prolonged isovolumic relaxation period (IRP) reflecting reduced rate of fall of left ventricular pressure. Eighty four patients with proven hypertrophic cardiomyopathy and 31 normal subjects were studied by simultaneous record...

journal_title：Postgraduate medical journal

authors： Alvares RF,Goodwin JF

更新日期：1986-06-01 00:00:00

abstract：:Several cardiorespiratory diseases can complicate human immunodeficiency virus infection. Primary pulmonary hypertension is a rare clinical disorder which carries a bad prognosis. More than 90 cases of HIV-associated primary pulmonary hypertension have been reported to date. Although its pathogenesis remains unknown, ...

journal_title：Postgraduate medical journal

authors： Golpe R,Fernandez-Infante B,Fernandez-Rozas S

更新日期：1998-07-01 00:00:00

abstract：:Antiphospholipid syndrome is a disorder of recurrent vascular thrombosis, pregnancy loss and thrombocytopenia associated with persistently elevated levels of antiphospholipid antibodies. It was first described in a group of patients with systemic lupus erythematosus but has since been associated with a wide range of c...

journal_title：Postgraduate medical journal

authors： Samadian S,Estcourt L

更新日期：1999-01-01 00:00:00

abstract：:A high proportion (40%) of patients with definite myocardial ischaemia who were questioned on admission to a Cardiac Monitoring Unit had experienced preceding chest pain which had been misinterpreted by both the patients themselves and doctors as 'indigestion' and which had often been inappropriately treated. 'Indiges...

journal_title：Postgraduate medical journal

authors： Simpson FG,Kay J,Aber CP

更新日期：1984-05-01 00:00:00

abstract：:A 75 year old woman was treated for over three years with the somatostatin analogue, octreotide for an insulinoma. She had presented in a hypoglycaemic coma. C-peptide and insulin concentrations were both raised and an area of increased vascularity within the pancreas was shown by angiography. No lesion was found at l...

journal_title：Postgraduate medical journal

authors： Craig CE,Gallen IW

更新日期：2002-10-01 00:00:00

abstract：:Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200 years following Withering's groundbreaking work depicting the therapeutic benefit of the common botanical foxglove in his 1785 monograph. The use of digoxin preceded any randomised evidence or even basic understanding of its ...

journal_title：Postgraduate medical journal

authors： Stucky MA,Goldberger ZD

更新日期：2015-09-01 00:00:00

abstract：:The new UK Foundation Programme is competency based, with a trainee's progression dependent on achieving and demonstrating a range of competencies. However, we do not know whether all rotations, comprising different combinations of specialties, will enable the foundation programme trainees to acquire these competencie...

journal_title：Postgraduate medical journal

authors： Higgins R,Cavendish S

更新日期：2006-10-01 00:00:00

abstract：:A case is reported where the use of i.v. disopyramide for a supraventricular tachycardia resulted in a more serious ventricular dysrhythmia giving hypotension and this probably contributed to the development of a myocardial infarction. Attention is drawn to the possible risk. ...

journal_title：Postgraduate medical journal

authors： Dibble JB,Webster NR

更新日期：1979-09-01 00:00:00

abstract：:The case is reported of a patient presenting with recurrent acute myocardial infarction due to stent thrombosis resulting from possible clopidogrel resistance caused by interaction between clopidogrel and anti-tuberculosis drugs. A brief overview of drug interaction as a risk factor for clopidogrel resistance is given...

journal_title：Postgraduate medical journal

authors： Srinivasan M,Smith D

更新日期：2008-04-01 00:00:00

abstract：:A severe case of the cast syndrome is described following Harrington rod distraction and application of a body cast. The case was unusual as it presented late with no warning symptoms and progressed rapidly to death. ...

journal_title：Postgraduate medical journal

authors： Kennedy RH,Cooper MJ

更新日期：1983-08-01 00:00:00