Secondary hypertension: a condition not to be missed.

abstract：:The effect of digoxin (0.25 mg t.d.s.) given orally for 5 days, on sodium excretion, plasma renin activity, plasma aldosterone and blood pressure has been studied in 6 normotensive subjects, on a constant sodium intake. Average serum digoxin level measured in 5 subjects on the 5th day of treatment was in the upper ran...

journal_title：Postgraduate medical journal

authors： Cappuccio FP,Markandu ND,Sagnella GA,MacGregor GA

更新日期：1986-04-01 00:00:00

abstract：:The effect of beta-blockers in improving exercise tolerance in angina pectoris can be accounted for by the reduction in heart rate and arterial pressure than they produce. The failure of a few patients to respond despite reduction in heart rate and the failure of those who do respond to obtain the full expected benefi...

journal_title：Postgraduate medical journal

authors： Robinson BF

更新日期：1976-01-01 00:00:00

abstract：:Prostate cancer is receiving ever more publicity with the result that more men are having their prostate specific antigen checked and a greater proportion of men are diagnosed with potentially curable localised disease. Advances in the therapeutic modalities including radical surgery, external beam radiotherapy, and b...

journal_title：Postgraduate medical journal

authors： Bott SR,Birtle AJ,Taylor CJ,Kirby RS

更新日期：2003-10-01 00:00:00

abstract：:A 61-year-old patient with treated Conn's syndrome due to multiple bilateral adrenocortical adenomata developed primary hyperparathyroidism. At operation, a parathyroid adenoma and a thyroid colloid nodule were found. Although adrenocortical adenomata and hyperplasia are common findings in multiple endocrine adenopath...

journal_title：Postgraduate medical journal

authors： Fertig A,Webley M,Lynn JA

更新日期：1980-01-01 00:00:00

abstract：:High flow arteriogenic priapism is uncommon and usually occurs after trauma to the genitoperineal area. The onset of prolonged erection can be delayed and is often relatively pain free. Arteriography in this case illustrated the causative bilateral arteriocavernosal fistulae and pseudoaneurysms. Treatment consisted of...

journal_title：Postgraduate medical journal

authors： Gujral S,MacDonagh RP,Cavanagh PM

更新日期：2001-03-01 00:00:00

abstract：:This report deals with a patient with long standing myasthenia gravis treated with a small dose of corticosteroids. The response to treatment was prompt and the post-therapeutic deterioration in function was minimal and cholinergic in nature. It is suggested that the dose of anticholinesterases be reduced concomitantl...

journal_title：Postgraduate medical journal

authors： Dandona P,Corkan EJ,Sladen GE

更新日期：1977-06-01 00:00:00

abstract：:Essential tremor is the most common cause of tremor involving upper limbs, head and voice. The first line of treatment for limb tremor is pharmacotherapy with propranolol or primidone. However, these two drugs reduce the tremor severity by only half. In medication refractory and functionally disabling tremor, alternat...

journal_title：Postgraduate medical journal

authors： Sharma S,Pandey S

更新日期：2020-02-01 00:00:00

abstract：:Parasites in the human breast are uncommon but not rare. Cysticercus and filariasis in fine needle breast aspirates have been documented and their cytomorphology is well characterised. However, the host tissue response to these parasites and the factors responsible for their initiation are not clear. Over a 21 year pe...

journal_title：Postgraduate medical journal

authors： Sahai K,Kapila K,Verma K

更新日期：2002-03-01 00:00:00

abstract：:Antibiotic resistance is an important concern for patients, physicians, healthcare managers, and policymakers. Inappropriate antimicrobial prescribing fuels the evolution of resistance, while poor basic hygiene facilitates the spread of resistant microbes between patients and healthcare staff. The development of infec...

journal_title：Postgraduate medical journal

authors： Barlow G,Nathwani D

更新日期：2005-11-01 00:00:00

abstract：:Two cases of patients with ischaemic colitis requiring operative treatment are presented. Both had received a commonly used psychotropic drug in large dosage before the acute episode. Evidence is produced which may link the drugs used with the condition of ischaemic colitis. ...

journal_title：Postgraduate medical journal

authors： Gollock JM,Thomson JP

更新日期：1984-08-01 00:00:00

abstract：:Serum thyrotrophin has been measured before and after the intravenous administration of 200 micrograms of thyrotrophin-releasing hormone in 91 white subjects (33 stable diabetic patients and 58 healthy controls), none of whom had any clinical evidence of thyroid or pituitary dysfunction. Seven of the diabetic subjects...

journal_title：Postgraduate medical journal

authors： Small M,Cohen HN,MacLean JA,Beastall GH,MacCuish AC

更新日期：1986-06-01 00:00:00

abstract：:Long lists of causes of peripheral neuropathy make peripheral nerve disease a dry and uninspiring subject. A simple scheme based on the answers to just six questions should enable the clinician to recognise characteristic patterns, investigate relevant subgroups appropriately, and identify treatable disorders quickly:...

journal_title：Postgraduate medical journal

authors： Overell JR

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Obesity in mid-life may increase the risk of subsequent dementia. Our objective was to study this risk, focusing on differences by age at the time of recording of obesity, in a large defined population. METHODS:A record linkage cohort study was undertaken using national administrative statistical data on hos...

journal_title：Postgraduate medical journal

authors： Wotton CJ,Goldacre MJ

更新日期：2014-10-01 00:00:00

abstract：:The present anti-racial discrimination legislation in the United Kingdom is embodied in the 1976 Race Relations Act. In essence this Act attempts to avoid any form of direct or indirect discrimination on the basis of racial or ethnic origin. However, health professionals are acutely aware that there are important raci...

journal_title：Postgraduate medical journal

authors： Bedi R,MacEwen M

更新日期：1990-12-01 00:00:00

abstract：:Hypertension is the most common chronic disease in the West Indies, and is a major health problem today being among the 10 most common causes of death in the English-speaking territories of the region. Most patients have essential hypertension. Renal failure, stroke, and cardiac failure are the most common complicatio...

journal_title：Postgraduate medical journal

authors： Grell GA

更新日期：1983-10-01 00:00:00

abstract：:A female patient demonstrating a previously not reported constellation of polyglandular autoimmune syndrome type III (including autoimmune thyroiditis, Graves' ophthalmopathy, insulin-dependent diabetes mellitus and vitiligo), coeliac disease and sarcoidosis is described. This may be a random association but might als...

journal_title：Postgraduate medical journal

authors： Papadopoulos KI,Hallengren B

更新日期：1993-01-01 00:00:00

abstract：:Greater trochanteric pain syndrome (GTPS) is a commonly diagnosed regional pain syndrome with a wide spectrum of aetiologies, reflecting the anatomy of the structures outside the hip joint capsule. There are five muscle tendons that insert on to the greater trochanter and three bursae in the region of the greater troc...

journal_title：Postgraduate medical journal

authors： Chowdhury R,Naaseri S,Lee J,Rajeswaran G

更新日期：2014-10-01 00:00:00

abstract：:Focused assessment with sonography in trauma (FAST) is a limited ultrasound scan performed in the emergency department to assess patients admitted with blunt abdominal trauma (BAT). It is normally undertaken by emergency physicians in order to identify the presence of free fluid, which may represent haemoperitoneum. T...

journal_title：Postgraduate medical journal

authors： Smith J

更新日期：2010-05-01 00:00:00

abstract：:A case of acute necrotizing pancreatitis in a 53-year-old man with an ectopic adrenocorticotrophin (ACTH) producing bronchial carcinoma is described. The aetiology of acute pancreatitis in relation to steroid therapy and malignancy is discussed and it is suggested that excess endogenous steroid production may also cau...

journal_title：Postgraduate medical journal

authors： Clague HW,Warren B,Krasner N

更新日期：1984-09-01 00:00:00

abstract：:The effects of infusions of prostaglandin E1 (PGE1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. Thirteen patients with atherosclerotic vascular disease received intravenous PGE1 25 mg/kg/min for 6 hours daily for 5 days. Prostaglandin E1 had no effect on platelet uptake at athero...

journal_title：Postgraduate medical journal

authors： Sinzinger H,O'Grady J,Fitscha P

更新日期：1987-04-01 00:00:00

abstract：:We report what we believe is the first recorded case of Mondor's disease associated with metastatic lung cancer presenting in the breast. An association between Mondor's disease and primary breast cancer has been described previously. In patients with Mondor's disease and primary breast cancer has been described previ...

journal_title：Postgraduate medical journal

authors： Courtney SP,Polacarz S,Raftery AT

更新日期：1989-10-01 00:00:00

abstract：:A case of adenocarcinoma of the lung, in which high titre anticardiolipin antibodies were associated with recurrent venous thromboses resistant to all forms of therapy, is described. It is suggested that such an autoimmune response may be a contributory factor in the para-neoplastic development of vascular thromboses....

journal_title：Postgraduate medical journal

authors： Shaukat MN,Hughes P

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To determine changes in hepatitis B virus (HBV) prevalence across three different time periods in pregnant women. METHODS:This was a retrospective study of pregnant women attending four healthcare centres between January 1995 and May 2015. Data for serum hepatitis B surface antigen (HBsAg) and anti-HBs level...

journal_title：Postgraduate medical journal

authors： Furuncuoglu Y,Bolukbas FF,Bolukbas C,Torun P,Ozturk R

更新日期：2016-09-01 00:00:00

abstract：:It was considered that the first dose reaction occurring with prazosin may have been due either to hypotension or to a specific reduction in cerebral blood flow. The development of a quantitative non-invasion nuclear medicine technique for cerebral flow has now made it possible to investigate the effects of prazosin o...

journal_title：Postgraduate medical journal

authors： Rutland MD,Lee TY,Nimmon CC,Granowska M,Britton KE

更新日期：1980-12-01 00:00:00

abstract：:The gastric acid response and the buffer capacity of the stomach were measured in 30 control subjects and 22 duodenal ulcer patients in response to a masticatory (solid) and a non-masticatory (homogenized) meal having the same chemical composition. The peak acid output values were equal after a masticatory and after a...

journal_title：Postgraduate medical journal

authors： Dubey P,Nundy S

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVES:To determine whether exocrine pancreatic function is impaired in patients with coeliac disease (CD) in our population and to evaluate its clinical importance. METHODS:Pancreatic exocrine function was determined by measuring faecal elastase-1 (FE) concentration. CD was diagnosed by serological testing using ...

journal_title：Postgraduate medical journal

authors： Vujasinovic M,Tepes B,Volfand J,Rudolf S

更新日期：2015-09-01 00:00:00

abstract：:The development of clinical governance in New Zealand has been pivotal to the country's health policy since 2009. Some of the key findings from one component of a national assessment project, which involved interviews with health professionals and managers at 19 of the country's 20 district health boards, are reviewed...

journal_title：Postgraduate medical journal

authors： Gauld R

更新日期：2014-01-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:In a routine adult gastroenterological practice, seventeen (15%) of 123 patients had small-intestinal biopsies which were neither normal nor were completely flat as found in classical coeliac disease. Some of these had a possible cause for the mild mucosal abnormality, but in six there was no other apparent cause and ...

journal_title：Postgraduate medical journal

authors： Scott BB,Losowsky MS

更新日期：1977-03-01 00:00:00

abstract：:Two patients with a rise in cardiac troponin T (cTnT) concentrations during the course of lobar pneumonia, without any evidence of acute coronary syndrome or renal failure, are presented. The increase in cTnT concentration is considered a highly sensitive marker of cardiac injury, although it may also rise in other co...

journal_title：Postgraduate medical journal

authors： Weinberg I,Cukierman T,Chajek-Shaul T

更新日期：2002-04-01 00:00:00