Identification of an arginine vasopressin-like diuretic hormone from Locusta migratoria.

abstract：:Heme is central to oxygen sensing and utilization in all living organisms. It directly regulates numerous molecular and cellular processes for systems that sense or use oxygen. In mammals, heme plays an indispensable role in erythroid cell differentiation. To investigate heme regulatory functions, we identified, by di...

journal_title：Biochemical and biophysical research communications

authors： Zhu Y,Hon T,Zhang L

更新日期：1999-04-29 00:00:00

abstract：:The aims of this study are to identify the sex steroid-metabolizing cytochrome P450 enzymes of the vomeronasal organ (VNO) and to determine the activities of VNO microsomes to metabolize estradiol, progesterone, and testosterone. Several P450 isoforms, including CYP1A2, CYP2A, CYP2B, CYP2C, CYP2G1, and CYP3A, NADPH P4...

journal_title：Biochemical and biophysical research communications

authors： Gu J,Dudley C,Su T,Spink DC,Zhang QY,Moss RL,Ding X

更新日期：1999-12-09 00:00:00

abstract：:In neuroblastoma N1E 115 cells, carbachol, histamine and PGE1 elevated cyclic GMP content and, induced the efflux of preloaded 45Ca2+, the release of membrane-bound Ca2+ measured by fluorescent CTC, and the increase in [Ca2+]i as measured by Quin 2 fluorescence. The time course of the responses, the absolute requireme...

journal_title：Biochemical and biophysical research communications

authors： Ohsako S,Deguchi T

更新日期：1984-07-18 00:00:00

abstract：:The classified sediment with ethanol from sera of nude mice and humans showed a disturbing effect on L1210 cells in vitro and a lifesaving effect on L1210 cell-bearing mice in vivo. This factor was purified more than 2300-fold to a specific activity of approximately 1 X 10(5) U/mg by ethanol classified precipitation, ...

journal_title：Biochemical and biophysical research communications

authors： Sakagami Y,Manabe H

更新日期：1984-04-30 00:00:00

abstract：:A rabbit cytochrome P-450IIE2 full-length cDNA was cloned into a yeast episomal plasmid (YEp13) between the copper-responsive yeast metallothionein gene promoter (CUP1) and the iso-1-cytochrome c gene terminator (CYC1), and the cytochrome P-450 was expressed in Saccharomyces cerevisiae. The microsomal fraction prepare...

journal_title：Biochemical and biophysical research communications

authors： Pernecky SJ,Porter TD,Coon MJ

更新日期：1990-11-15 00:00:00

abstract：:Dopamine transporter (DAT) plays a key role in terminating synaptic dopaminergic transmission. DAT acts exclusively on the plasma membrane of presynaptic dopaminergic neurons and DAT gene is an appropriate model for the study of dopaminergic neuron-specific regulation of gene activity. DAT represents an important targ...

journal_title：Biochemical and biophysical research communications

authors： Kouzmenko AP,Pereira AM,Singh BS

更新日期：1997-11-26 00:00:00

abstract：:Based on pseudo amino acid (PseAA) composition and a novel hybrid feature selection frame, this paper presents a computational system to predict the PPIs (protein-protein interactions) using 8796 protein pairs. These pairs are coded by PseAA composition, resulting in 114 features. A hybrid feature selection system, mR...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Cai Y,Lu W,Feng K,Peng C,Niu B

更新日期：2009-03-06 00:00:00

abstract：:Regulation of the bone sialoprotein (BSP) gene is important in the differentiation of osteoblasts, in bone matrix mineralization, and in tumor metastasis. We investigated BSP gene transcription by performing functional analysis of the 9256bp of the 5' flanking region of the murine BSP gene containing its promoter. We ...

journal_title：Biochemical and biophysical research communications

authors： Tu Q,Yamauchi M,Pageau SC,Chen JJ

更新日期：2004-04-02 00:00:00

abstract：:Synthesis of melanin starts from the conversion of L-tyrosine to 3,4-dihydroxyphenylalanine (L-dopa) and then the oxidation of L-dopa yields dopaquinone by tyrosinase. Therefore, tyrosinase inhibitors have been established as important constituents of depigmentation agents. Recently, polyhydroxystilbene compounds, whi...

journal_title：Biochemical and biophysical research communications

authors： Ohguchi K,Tanaka T,Kido T,Baba K,Iinuma M,Matsumoto K,Akao Y,Nozawa Y

更新日期：2003-08-08 00:00:00

abstract：:This study investigated the effects of shear stress on gene expression of prostacyclin synthesis-related enzymes cyclooxygenases (COX-1 and COX-2), prostacyclin synthase (PGS), and thromboxane synthase (TXS) and their metabolites prostaglandin (PGI(2)) and thromboxane A(2) (TXA(2)) in endothelium of intact conduit ves...

journal_title：Biochemical and biophysical research communications

authors： Doroudi R,Gan LM,Selin Sjögren L,Jern S

更新日期：2000-03-05 00:00:00

abstract：:Determination of the rates of saccharide diffusions by the proteoliposomes showed that the outer membrane of Pseudomonas aeruginosa only possesses small diffusion pores and that protein F might have not been involved in the pore formation. Proteoliposomes containing stachyose or Dextan T-10 showed the same relative di...

journal_title：Biochemical and biophysical research communications

authors： Yoshihara E,Gotoh N,Nakae T

更新日期：1988-10-14 00:00:00

abstract：:Force impulse is thought to be generated in muscle when myosin head (S-1), while weakly bound to actin filament, undergoes orientational change to form a strong (rigor) bond with actin. There is ample evidence that this bond involves interaction of 1 myosin head with 1 actin monomer. However, X-ray diffraction data of...

journal_title：Biochemical and biophysical research communications

authors： Andreev OA,Borejdo J

更新日期：1991-05-31 00:00:00

abstract：:Oct4, a member of the POU-domain transcription factor family, has been implicated in the cancer stem cell (CSC)-like properties of various cancers. However, the precise role of Oct4 in colorectal CSC initiation remains uncertain. Numerous studies have demonstrated a strong link between inflammation and tumorigenesis i...

journal_title：Biochemical and biophysical research communications

authors： Chang CJ,Chien Y,Lu KH,Chang SC,Chou YC,Huang CS,Chang CH,Chen KH,Chang YL,Tseng LM,Song WS,Wang JJ,Lin JK,Huang PI,Lan YT

更新日期：2011-11-18 00:00:00

abstract：:A new form of cytochrome P-450 has been purified from untreated male rabbit liver microsomes. This form was designated P-450 LM2b on the basis of its electrophoretic mobility on SDS polyacrylamide gel, where it migrates as a polypeptide of apparent molecular weight of 50,250. This hemoprotein exhibits a maximum at 448...

journal_title：Biochemical and biophysical research communications

authors： Bonfils C,Larroque C,Maurel P

更新日期：1986-02-13 00:00:00

abstract：:This study evaluates the influence of S1033 vinculin phosphorylation on the mechanical properties of cells. We demonstrate that MEFvcl KO cells transfected with the non-phosphorylatable eGFP-vinculin mutant S1033A are of lower stiffness compared to MEFvcl Rescue and phospho-mimicking mutant S1033D cells, which were of...

journal_title：Biochemical and biophysical research communications

authors： Auernheimer V,Goldmann WH

更新日期：2014-07-25 00:00:00

abstract：:ATP-binding cassette sub-family G member 2 (ABCG2) confers to the major phenotypes of side population (SP) cells, the cancer stem-like cells. In this study, the SP cells displayed a distinctly higher ABCG2 expression level, sphere formation efficiency (SFE) and growth rate even under hypoxia condition. CXCR4 overexpre...

journal_title：Biochemical and biophysical research communications

authors： He C,Zhang H,Wang B,He J,Ge G

更新日期：2018-10-28 00:00:00

abstract：:Cross-linking the antigen receptor on B cells results in a rapid increase in protein tyrosine kinase activity as detected by increased phosphorylation on tyrosine residues of multiple proteins. Although the identity of most of this substrates remains unknown, some have been proposed. One possible substrate of the anti...

journal_title：Biochemical and biophysical research communications

authors： Roifman CM,Wang G

更新日期：1992-03-16 00:00:00

abstract：:The change of transferrin receptors in regenerating rat liver cells after partial hepatectomy was demonstrated. The binding of 125I-labeled transferrin to the cells began to increase after 24 h of partial hepatectomy and reached about double that of the non-operated normal rat liver cells. A Scatchard analysis of bind...

journal_title：Biochemical and biophysical research communications

authors： Tei I,Makino Y,Kadofuku T,Kanamaru I,Konno K

更新日期：1984-06-15 00:00:00

abstract：:The exon/intron organization and the structure of the 5' flanking region of the human thyrotropin receptor gene (hTSH-R) were determined. The hTSH-R gene spans more than 60 kb and is split into ten exons. The extracellular domain is encoded by the first nine exons and part of the last exon, whereas the transmembrane a...

journal_title：Biochemical and biophysical research communications

authors： Gross B,Misrahi M,Sar S,Milgrom E

更新日期：1991-06-14 00:00:00

abstract：:Isoprenoids comprise a diverse group of natural products with a broad range of metabolic functions. Isoprenoids are synthesized from prenyl pyrophosphates by prenyltransferases that catalyze the isoprenoid chain-elongation process to different chain lengths. We hereby present the crystal structure of geranylgeranyl py...

journal_title：Biochemical and biophysical research communications

authors： Kim S,Kim EJ,Park JB,Kim SW,Kim KJ

更新日期：2019-10-20 00:00:00

abstract：:Treatment of newborn murine epidermal cells with phospholipase C results in the generation of a chemiluminescence response similar to that previously described for phorbol ester tumor promoters. Based on inhibitor studies, the oxidant, believed to be superoxide anion, is most likely generated from lipoxygenase metabol...

journal_title：Biochemical and biophysical research communications

authors： Fischer SM,Baldwin JK,Adams LM

更新日期：1985-09-30 00:00:00

abstract：:The delta subunit of the epithelial sodium channel (δENaC) is a member of the ENaC/degenerin family of ion channels. δENaC is distinct from the related α-, β- and γENaC subunits, known for their role in sodium homeostasis and blood pressure control, as δENaC is expressed in brain neurons and activated by external prot...

journal_title：Biochemical and biophysical research communications

authors： Chang T,Ke Y,Ly K,McDonald FJ

更新日期：2011-08-05 00:00:00

abstract：:Matrin 3, a nuclear matrix protein has potential (1) to withhold promiscuously edited RNAs within the nucleus in cooperation with p54(nrb) and PSF, (2) to mediate NMDA-induced neuronal death, and (3) to modulate promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). We identified a biparti...

journal_title：Biochemical and biophysical research communications

authors： Hisada-Ishii S,Ebihara M,Kobayashi N,Kitagawa Y

更新日期：2007-03-02 00:00:00

abstract：:Runt-related transcription factor-2 (RUNX2) is expressed as two isoforms (type-I and type-II) differing only in their amino terminal sequences. The amino terminus of type-I contains MRIPV instead of MASNSLFSAVTPCQQSFFW in type-II. Although type-II mRNA has been considered osteoblast specific, the RUNX2 protein isoform...

journal_title：Biochemical and biophysical research communications

authors： Sudhakar S,Katz MS,Elango N

更新日期：2001-08-10 00:00:00

abstract：:We provide the first functional evidence that calcitonin gene-related peptide (8-37) induces a direct vasoconstriction and reversibly antagonizes vasodilation of the mesenteric arterial bed induced by calcitonin gene-related peptide (CGRP) suggesting that CGRP (8-37) is a competitive antagonist of vascular CGRP recept...

journal_title：Biochemical and biophysical research communications

authors： Han SP,Naes L,Westfall TC

更新日期：1990-04-30 00:00:00

abstract：:miRNAs are recently found playing important roles in osteogenesis. In this study, we identified that miR-222-3p decreased during osteogenic differentiation of human mesenchymal stem cells (hBMSCs) using Quantitative Real-Time Reverse Transcription PCR (qRT-PCR). Furthermore, we investigated the effect of miR-222-3p on...

journal_title：Biochemical and biophysical research communications

authors： Yan J,Guo D,Yang S,Sun H,Wu B,Zhou D

更新日期：2016-02-12 00:00:00

abstract：:Near-full length complementary DNA (cDNA) clones encoding turkey growth hormone (GH) have been isolated from a pituitary library. The longer of the two turkey GH cDNA clones that were sequenced is 803 base pairs (bp) in length and contains 41 nucleotides of the 5'-untranslated region (UTR), an open reading frame of 64...

journal_title：Biochemical and biophysical research communications

authors： Foster DN,Kim SU,Enyeart JJ,Foster LK

更新日期：1990-12-31 00:00:00

abstract：:The ΔpH-dependent/Tat pathway is unique for using only the proton motive force for driving proteins transport across the thylakoid membrane in chloroplasts. 9-aminoacridine fluorescence quenching is widely used to monitor the ΔpH developed across the thylakoid membrane in the light. However, this method suffers from l...

journal_title：Biochemical and biophysical research communications

authors： Yang H,Pu X,Wang L,Liu L,Theg SM

更新日期：2017-04-22 00:00:00

abstract：:Epidermal 7-ethoxyresorufin O-deethylase (EROD) activity was elevated greater than 100-fold within 4 to 7 h of topical treatment of SENCAR mice with 100 nmol dibenz[a,c]anthracene (DB[a,c]A). Treatment of skin with 2 micrograms of 12-O-tetradecanoylphorbol-13-acetate (TPA) 2 to 8 h prior to DB[a,c]A application suppre...

journal_title：Biochemical and biophysical research communications

authors： Reiners JJ Jr,Cantu AR,Schöller A

更新日期：1992-07-31 00:00:00

abstract：:Disrupted-in-Schizophrenia 1 (DISC1) is a promising genetic risk factor for major mental disorders. Many groups repeatedly reported a role for DISC1 in brain development in various strains of mice and rats by using RNA interference (RNAi) approach. Nonetheless, due to the complexity of its molecular disposition, such ...

journal_title：Biochemical and biophysical research communications

authors： Kubo K,Tomita K,Uto A,Kuroda K,Seshadri S,Cohen J,Kaibuchi K,Kamiya A,Nakajima K

更新日期：2010-10-01 00:00:00