Vibratory and cooling detection thresholds compared with other tests in diagnosing and staging diabetic neuropathy.

abstract：OBJECTIVE:To study the metabolic effect and the variability of the effect elicited by inhalation of 87.2 U insulin powder combined with an absorption enhancer. The metabolic effect was compared with that of 10.2 U regular insulin injected subcutaneously and of 5.5 U regular insulin given intravenously RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Heinemann L,Klappoth W,Rave K,Hompesch B,Linkeschowa R,Heise T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Acarbose inhibits alpha-glucosidases of the small intestine and thus delays glucose release from complex carbohydrates. Therefore, its efficacy and acceptability as a first-line drug in non-insulin-dependent diabetes mellitus (NIDDM) insufficiently treated with diet alone was tested in a randomized double-bli...

journal_title：Diabetes care

authors： Hanefeld M,Fischer S,Schulze J,Spengler M,Wargenau M,Schollberg K,Fücker K

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine whether objectively measured physical activity and dietary macronutrient intake differentially predict body fat in adolescent girls with type 1 diabetes and control girls. RESEARCH DESIGN AND METHODS:This study comprised 23 girls (12-19 years) with type 1 diabetes a...

journal_title：Diabetes care

authors： Särnblad S,Ekelund U,Aman J

更新日期：2006-06-01 00:00:00

abstract：:Given the importance of glycemic control in the development of diabetes complications, the plethora of tools now available to monitor the day-to-day trends in glycemia is remarkable. In this regard, self-monitoring of blood glucose (SMBG) has been considered a key component of patient management. Arguably, there remai...

journal_title：Diabetes care

authors： Polonsky WH,Fisher L

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To examine medical and mental health care expenditures for large numbers of individuals with diabetes enrolled in employment-sponsored insurance plans. RESEARCH DESIGN AND METHODS:Health insurance billing data for approximately 1.3 million individuals enrolled in health insurance plans sponsored by 862 large...

journal_title：Diabetes care

authors： Peele PB,Lave JR,Songer TJ

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:Hypertriglyceridemia is associated with cardiovascular disease in diabetes. Fibrates effectively lower, but do not always normalize, serum triglyceride levels. Fish oil supplements may then be added to lower serum triglyceride levels. Doubt remains whether the net effect of fish oil intake on glycemic control...

journal_title：Diabetes care

authors： Friedberg CE,Janssen MJ,Heine RJ,Grobbee DE

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:This study examined the prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction (HFpEF). RESEARCH DESIGN AND METHODS:This analysis included 3,385 patients (mean age 69 ± 9.6 years; 49% male; 89% white) with HFpEF from the Treatment o...

journal_title：Diabetes care

authors： Sandesara PB,O'Neal WT,Kelli HM,Samman-Tahhan A,Hammadah M,Quyyumi AA,Sperling LS

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS:Patients were randomly or consecutively selected from primary/secondary care. PROMs inclu...

journal_title：Diabetes care

authors： Bradley C,Eschwège E,de Pablos-Velasco P,Parhofer KG,Simon D,Vandenberghe H,Gönder-Frederick L

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To summarize the efficacy of metformin in reducing BMI and cardiometabolic risk in obese children and adolescents without diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). Double-blind RCTs of > or =6 months duration in obese subj...

journal_title：Diabetes care

authors： Park MH,Kinra S,Ward KJ,White B,Viner RM

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Diabetes and its complications disproportionately affect African Americans and Hispanics. Complications could be prevented with appropriate medical care. We compared five processes of care and three outcomes of care among African Americans, Hispanics, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We u...

journal_title：Diabetes care

authors： Bonds DE,Zaccaro DJ,Karter AJ,Selby JV,Saad M,Goff DC Jr

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:This study was designed to examine metabolic and hormonal effects of long-term exercise in healthy subjects and insulin-dependent (type I) diabetic patients. RESEARCH DESIGN AND METHODS:Two studies were performed. First, 16 healthy males (32 +/- 3 yr) were studied during a semitriathlon competition (2 km swi...

journal_title：Diabetes care

authors： Koivisto VA,Sane T,Fyhrquist F,Pelkonen R

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes is associated with increased plasma concentrations of coagulation and inflammation markers. Different studies have shown that treatment with hydroxymethylglutaryl-CoA reductase inhibitors (statins) is associated with antithrombotic and anti-inflammatory effects in addition to a cholesterol-low...

journal_title：Diabetes care

authors： Sommeijer DW,MacGillavry MR,Meijers JC,Van Zanten AP,Reitsma PH,Ten Cate H

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Regular physical activity (PA) reduces the risk of developing type 2 diabetes, and different subtypes of dysglycemia have shown different associations with PA. To better understand the associations of PA and glucose homeostasis, we examined the association of objectively measured PA energy expenditure (PAEE) ...

journal_title：Diabetes care

authors： Hansen AL,Carstensen B,Helge JW,Johansen NB,Gram B,Christiansen JS,Brage S,Lauritzen T,Jørgensen ME,Aadahl M,Witte DR,ADDITION-Denmark Steering Committee.

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To determine the rheological properties of polymorphonuclear leukocytes (PMN) from non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:The deformability of PMN from 33 NIDDM subjects, 13 with impaired glucose tolerance (IGT), and 22 with normal glucose tolerance (NGT) was st...

journal_title：Diabetes care

authors： Pécsvarády Z,Fisher TC,Darwin CH,Fabók A,Maqueda TS,Saad MF,Meiselman HJ

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Anti-programmed cell death-1 (anti-PD-1) antibodies have revolutionized advanced cancer therapy. Anti-PD-1 therapy is responsible for immune-related adverse events, with frequent endocrine manifestations, including acute-onset type 1 diabetes. Acquired generalized lipodystrophy (AGL) is a rare disease, believ...

journal_title：Diabetes care

authors： Jehl A,Cugnet-Anceau C,Vigouroux C,Legeay AL,Dalle S,Harou O,Marchand L,Lascols O,Caussy C,Thivolet C,Laville M,Disse E

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To assess the dose-ranging efficacy and safety of LX4211, a dual inhibitor of sodium-glucose cotransporter (SGLT) 1 and SGLT2, in type 2 diabetes. RESEARCH DESIGN AND METHODS:Type 2 diabetic patients inadequately controlled on metformin were randomly assigned to 75 mg once daily, 200 mg once daily, 200 mg tw...

journal_title：Diabetes care

authors： Rosenstock J,Cefalu WT,Lapuerta P,Zambrowicz B,Ogbaa I,Banks P,Sands A

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To examine the association of renal function in diabetic patients with apolipoprotein (apo) E polymorphism. RESEARCH DESIGN AND METHODS:Apo E genotypes, lipid and lipoprotein serum levels, creatinine clearance (CCr), and excretion of marker proteins were determined in German type 1 (IDDM; n = 162) and type 2...

journal_title：Diabetes care

authors： Werle E,Fiehn W,Hasslacher C

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To compare the effects of repaglinide, glipizide, and glibenclamide on insulin secretion and postprandial glucose after a single standard 500-kcal test meal. RESEARCH DESIGN AND METHODS:A total of 12 type 2 diabetic patients with early diabetes (mean HbA(1c) of 6.1%) and 12 matched control subjects were enro...

journal_title：Diabetes care

authors： Cozma LS,Luzio SD,Dunseath GJ,Langendorg KW,Pieber T,Owens DR

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The aim was to explore relationships between work-related factors, work-related diabetes distress (WRDD), diabetes distress (measured by Problem Areas in Diabetes [PAID]-5 scale), intentional hyperglycemia at work (IHW), and glycemic control. RESEARCH DESIGN AND METHODS:A cross-sectional survey was conducted...

journal_title：Diabetes care

authors： Hansen UM,Skinner T,Olesen K,Willaing I

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the metabolic effects of metformin, as compared with placebo, in type 2 diabetic patients intensively treated with insulin. RESEARCH DESIGN AND METHODS:Metformin improves glycemic control in poorly controlled type 2 diabetic patients. Its effect in type 2 diabetic patients who are intensively ...

journal_title：Diabetes care

authors： Wulffelé MG,Kooy A,Lehert P,Bets D,Ogterop JC,Borger van der Burg B,Donker AJ,Stehouwer CD

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes is associated with a markedly increased risk of stroke, but only a few studies on the incidence of stroke in type 1 diabetes exist. Therefore, we assessed the incidence of stroke in patients with type 1 diabetes and studied the impact of diabetic nephropathy (DN) and severe diabetic retinopath...

journal_title：Diabetes care

authors： Hägg S,Thorn LM,Putaala J,Liebkind R,Harjutsalo V,Forsblom CM,Gordin D,Tatlisumak T,Groop PH,FinnDiane Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:We have investigated age-period-cohort effects and spatial and temporal trends for the incidence of type 1 diabetes among 0- to 14-year-old children in Norway. RESEARCH DESIGN AND METHODS:We included children with the diagnosis of type 1 diabetes in Norway during 1973-1982 and 1989-2003. We studied age, cale...

journal_title：Diabetes care

authors： Aamodt G,Stene LC,Njølstad PR,Søvik O,Joner G,Norwegian Childhood Diabetes Study Group.

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To determine contributions of trunk and extremity adiposity to cardiometabolic risk factors (blood pressure, fasting blood glucose, HDL cholesterol, and triglycerides) among white and African American adults. RESEARCH DESIGN AND METHODS:The sample consisted of 1,129 white women, 779 African American women, 1...

journal_title：Diabetes care

authors： Hu G,Bouchard C,Bray GA,Greenway FL,Johnson WD,Newton RL Jr,Ravussin E,Ryan DH,Katzmarzyk PT

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The risk of myocardial infarction (MI) in patients with diabetes is greater than for patients without diabetes. Consequently, prophylactic treatment is recommended for patients with diabetes and risk factors for ischemic heart disease. We aimed to estimate the risk of adverse cardiac events in patients with a...

journal_title：Diabetes care

authors： Olesen KKW,Madsen M,Egholm G,Thim T,Jensen LO,Raungaard B,Bøtker HE,Sørensen HT,Maeng M

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To explore the hypothesis that a relationship exists between free radical activity and abnormalities in hemostasis in NIDDM. RESEARCH DESIGN AND METHODS:The use of the total radical-trapping antioxidant parameter (TRAP) has very recently been proposed to explore the antioxidant property of a plasma and their...

journal_title：Diabetes care

authors： Ceriello A,Bortolotti N,Pirisi M,Crescentini A,Tonutti L,Motz E,Russo A,Giacomello R,Stel G,Taboga C

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:To evaluate effects of vildagliptin and metformin on blood pressure (BP) and heart rate (HR) responses to intraduodenal (ID) glucose in diet-controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:Study A compared vildagliptin (50 mg) and placebo, given 60 min before a 120-min ID glucose infusion at 2 or 4 k...

journal_title：Diabetes care

authors： Wu T,Trahair LG,Little TJ,Bound MJ,Zhang X,Wu H,Sun Z,Horowitz M,Rayner CK,Jones KL

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. RESEARCH DESIGN AND METHODS:We retrospectively analyzed data from hybrid closed-loop studies involving young children (1-6 years old, n = 20), children (7-12 years, n = 21), adolescents (13-17 years, n = 1...

journal_title：Diabetes care

authors： Dovc K,Boughton C,Tauschmann M,Thabit H,Bally L,Allen JM,Acerini CL,Arnolds S,de Beaufort C,Bergenstal RM,Campbell F,Criego A,Dunger DB,Elleri D,Evans ML,Fröhlich-Reiterer E,Hofer S,Kapellen T,Leelarathna L,Pieber T

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Dyslipidemia contributes to the progression of microvascular disease in diabetes. However, different lipid variables may be important at different stages of nephropathy. This study examines the pattern of dyslipidemia associated with the progression of nephropathy in patients with type 1 diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Thomas MC,Rosengård-Bärlund M,Mills V,Rönnback M,Thomas S,Forsblom C,Cooper ME,Taskinen MR,Viberti G,Groop PH

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Elevated heart rate has been predictive of cardiovascular disease and has been proposed as a global index of the autonomic nervous system influence on the heart. Hyperinsulinism has been shown to trigger sympathetic activity experimentally; however, the clinical and epidemiological data on the association of ...

journal_title：Diabetes care

authors： Festa A,D'Agostino R Jr,Hales CN,Mykkänen L,Haffner SM

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Women with diabetes have a high incidence and complication rate of urinary tract infections (UTIs). Our aims were to compare current treatment strategies with respect to recurrence rates in women with diabetes with those without diabetes. RESEARCH DESIGN AND METHODS:We used a Dutch registration database cont...

journal_title：Diabetes care

authors： Schneeberger C,Stolk RP,Devries JH,Schneeberger PM,Herings RM,Geerlings SE

更新日期：2008-07-01 00:00:00