DNA double-strand breaks induced by very low X-ray doses are largely due to bystander effects.

abstract：:Relatively few data are available on the prevalence of hyperthyroidism (TSH concentrations of <0.3 mIU/liter, with normal or elevated concentrations of free T4) in individuals exposed to radioiodines at low levels. The accident at the Chornobyl (Chernobyl) nuclear plant in Ukraine on April 26, 1986 exposed large numbe...

journal_title：Radiation research

authors： Hatch M,Furukawa K,Brenner A,Olinjyk V,Ron E,Zablotska L,Terekhova G,McConnell R,Markov V,Shpak V,Ostroumova E,Bouville A,Tronko M

更新日期：2010-12-01 00:00:00

abstract：:1-(2-Fluoro-4-iodo-2,4-dideoxy-beta-L-xylopyranosyl)-2-nitroimidazole (FIAZP) has been synthesized and labeled with radioiodine (125I). Radioiodinated FIAZP is one of a series of sugar-coupled 2-nitroimidazoles developed in our laboratory as probes for noninvasive scintigraphic assessment of tumor hypoxia. An in vivo ...

journal_title：Radiation research

authors： Mannan RH,Mercer JR,Wiebe LI,Somayaji VV,Chapman JD

更新日期：1992-12-01 00:00:00

abstract：:The presence of low levels of oxygen may have profound effects on the cytotoxic activity of radiation, radiosensitizers, and bioreductive alkylating agents. As others have shown, low oxygen tensions may significantly alter rates of cellular and chemical oxygen consumption. When experiments are performed at very low ox...

journal_title：Radiation research

authors： Marshall RS,Koch CJ,Rauth AM

更新日期：1986-10-01 00:00:00

abstract：:Radioprotection in vitro by sulfhydryl (SH)-containing compounds is usually greater in aerated than in hypoxic cells. This observation has been cited recently as one of the reasons for the relatively greater effectiveness of radioprotectors such as WR-2721 in normal tissues compared to tumor cells. It is demonstrated ...

journal_title：Radiation research

authors： Held KD

更新日期：1985-03-01 00:00:00

abstract：:The response of the testes of two strains of adult rats (Sprague-Dawley and Wistar) to graded single doses and split doses of 230 kVp X rays has been investigated. A marked difference was noted between the strains in the response of the clonogenic spermatogonia to irradiation, as measured histologically by the repopul...

journal_title：Radiation research

authors： Delic JI,Schlappack OK,Harwood JR,Stanley JA

更新日期：1987-10-01 00:00:00

abstract：:We report results for chromosomal aberrations in human peripheral blood lymphocytes after they were exposed to high-energy iron ions with or without shielding at the HIMAC, AGS and NSRL accelerators. Isolated lymphocytes were exposed to iron ions with energies between 200 and 5000 MeV/nucleon in the 0.1-1-Gy dose rang...

journal_title：Radiation research

authors： Durante M,George K,Gialanella G,Grossi G,La Tessa C,Manti L,Miller J,Pugliese M,Scampoli P,Cucinotta FA

更新日期：2005-10-01 00:00:00

abstract：:This paper evaluates the global vitamin D effective UV (UV(vitd)) irradiances under cloudy conditions at a subtropical, southern hemisphere site. The UV(vitd) irradiances were analyzed on a horizontal plane and sampled at 5-min intervals over 18 months so that a wide range of parameters including cloud conditions, sol...

journal_title：Radiation research

authors： Turnbull DJ,Parisi AV,Schouten PW

更新日期：2010-05-01 00:00:00

abstract：:The non-random distribution of DNA breakage in PFGE (pulsed-field gel electrophoresis) experiments poses a problem of proper subtraction of the background DNA damage to obtain a fragment-size distribution due to radiation only. A naive bin-to-bin subtraction of the background signal will not result in the right DNA ma...

journal_title：Radiation research

authors： Ponomarev AL,Belli M,Hahnfeldt PJ,Hlatky L,Sachs RK,Cucinotta FA

更新日期：2006-12-01 00:00:00

abstract：:Radiation-induced acute myeloid leukemia (rAML) in C3H mice is commonly developed through inactivation of PU.1 transcription factor encoded in Sfpi1 on chromosome 2. PU.1 inactivation involves two steps: hemizygous deletion of the Sfpi1 gene (DSG) and point mutation of the allele Sfpi1 gene (PMASG). In this study, we ...

journal_title：Radiation research

authors： Ojima M,Hirouchi T,Etani R,Ariyoshi K,Fujishima Y,Kai M

更新日期：2019-12-01 00:00:00

abstract：:To characterize the differences in the radiosensitivity of individual populations of human hematopoietic stem/progenitor cells (HSPCs), we examined the relationship among cell surface antigens, clonogenic potential and radiation survival. The expressions of CD34, CD38, CD45RA, CD110 and Tie-2, early differentiation pa...

journal_title：Radiation research

authors： Takahashi K,Monzen S,Hayashi N,Kashiwakura I

更新日期：2010-02-01 00:00:00

abstract：:The effect of sodium bisulfite, a specific inhibitor of chromatin proteolysis, on radiation damage in rat thymocytes in vitro was examined. Rat thymocytes irradiated with 1 kR X rays in vitro were incubated at 37 degrees C with 10 mM glucose for 4 to 6 hr. During that time development of interphase death as judged by ...

journal_title：Radiation research

authors： Ohyama H,Shimizu M,Yamada T

更新日期：1983-07-01 00:00:00

abstract：:Inhalation and ingestion of 137Cs and other long-lived radionuclides can occur after large-scale accidental or malicious radioactive contamination incidents, resulting in a complex temporal pattern of radiation dose/dose rate, influenced by radionuclide pharmacokinetics and chemical properties. High-throughput radiati...

journal_title：Radiation research

authors： Shuryak I,Ghandhi SA,Turner HC,Weber W,Melo D,Amundson SA,Brenner DJ

更新日期：2020-10-16 00:00:00

abstract：:Experiments were performed to determine whether diurnal variations in apoptosis in the mouse small intestine after irradiation with 2.5 Gy gamma rays depended on the time of day that the mice were irradiated, the time of day that the mice were sacrificed or the interval between irradiation and sacrifice. Experiments w...

journal_title：Radiation research

authors： Ruifrok AC,Weil MM,Thames HD,Mason KA

更新日期：1998-04-01 00:00:00

abstract：:The health consequences of exposure to low-dose radiation combined with a solar particle event during space travel remain unresolved. The goal of this study was to determine whether protracted radiation exposure alters gene expression and oxidative burst capacity in the liver, an organ vital in many biological process...

journal_title：Radiation research

authors： Gridley DS,Coutrakon GB,Rizvi A,Bayeta EJ,Luo-Owen X,Makinde AY,Baqai F,Koss P,Slater JM,Pecaut MJ

更新日期：2008-03-01 00:00:00

abstract：:The hyperthermic inhibition of cellular DNA synthesis, i.e., reduction in replicon initiation and delay in DNA chain elongation, was previously postulated to be involved in the induction of chromosomal aberrations believed to be largely responsible for killing S-phase cells. Utilizing asynchronous Chinese hamster ovar...

journal_title：Radiation research

authors： Wong RS,Thompson LL,Dewey WC

更新日期：1988-04-01 00:00:00

abstract：:A new model for the survival of bacteria exposed to ionizing radiation is constructed in the framework of a target theory based on microdosimetric concepts, where single- and double-strand breaks of DNA and their repair in vivo can be described consistently in terms of the microdosimetric quantity j (number of effecti...

journal_title：Radiation research

authors： Iwanami S,Oda N

更新日期：1985-04-01 00:00:00

abstract：:Hormetic and adaptive responses induced by low-level radiation in hematopoietic and immune systems have been observed, as shown by stimulatory effects on cell growth and resistance to subsequent radiation-induced cytogenetic damage. However, in terms of cell death by apoptosis, the effects of low-level radiation are c...

journal_title：Radiation research

authors： Liu G,Gong P,Zhao H,Wang Z,Gong S,Cai L

更新日期：2006-04-01 00:00:00

abstract：:Caffeine is a model radiosensitizing agent that is thought to work by abrogating the radiation-induced G(2)-phase checkpoint. In this study, we examined the effect that various concentrations of caffeine had on cell cycle checkpoints and apoptosis in cells of a human lung carcinoma cell line and found that a concentra...

journal_title：Radiation research

authors： Qi W,Qiao D,Martinez JD

更新日期：2002-02-01 00:00:00

abstract：:Water:n-octanol partition coefficients (KD) were determined for a series of radioprotective thiols to ascertain whether these could be used to estimate reliably their rates of uptake into mammalian cells by passive diffusion. Values of KD determined for thiols in 0.1 M potassium phosphate, pH 7.4, at 22 degrees C were...

journal_title：Radiation research

authors： Newton GL,Aguilera JA,Kim T,Ward JF,Fahey RC

更新日期：1996-08-01 00:00:00

abstract：:The appearance of prostaglandins and thromboxane in mouse serum after X irradiation was observed by simultaneous quantitative analysis using gas chromatography/mass spectrometry/selected ion monitoring with stable isotope dilution methods. Mice of two strains (C57BL/CN Jcl and BALB/c) showed similar responses to X irr...

journal_title：Radiation research

authors： Yamaoka K,Obata T,Iriyama K,Iwasaki T,Hoshi Y

更新日期：1998-01-01 00:00:00

abstract：:Peroxidation of unconjugated polyunsaturated fatty acids such as linolenic acid proceeds through a free radical chain mechanism and is accompanied by the formation of conjugated dienes such as hydroperoxides. In an investigation of radiation-induced oxidation of aqueous linolenate, we have measured two indexes of pero...

journal_title：Radiation research

authors： Hindo J,Hauville C,Rémita S,Thérond P,Couturier M,Jore D,Gardès-Albert M

更新日期：2000-02-01 00:00:00

abstract：:In the decade after the bombings of Hiroshima and Nagasaki, several large cohorts of survivors were organized for studies of radiation health effects. The U.S. Atomic Bomb Casualty Commission (ABCC) and its U.S./Japan successor, the Radiation Effects Research Foundation (RERF), have performed continuous studies since ...

journal_title：Radiation research

authors： Cullings HM,Fujita S,Funamoto S,Grant EJ,Kerr GD,Preston DL

更新日期：2006-07-01 00:00:00

abstract：:Damage to intestine is a serious problem after accidental radiation exposure. To examine substances to ameliorate damage by postirradiation administration, we focused on the regeneration process after irradiation of the intestine. Using experimental systems, the effects of clinically used sex hormones on regeneration ...

journal_title：Radiation research

authors： Ishihara H,Tanaka I,Yakumaru H,Tanaka M,Satoh A,Ishiwata A,Yokochi K,Kurematsu A,Ueda J,Shibata T,Hachiya M,Akashi M

更新日期：2011-03-01 00:00:00

abstract：:While lifespan studies provide basic information for estimating the risk of ionizing radiation, findings on the effect of low-dose/low-dose-rate irradiation on the lifespan of mammals are controversial. Here we evaluate the effect of continuous exposure to low-dose-rate γ radiation on the lifespan of mice with acceler...

journal_title：Radiation research

authors： Nomura T,Sakai K,Ogata H,Magae J

更新日期：2013-06-01 00:00:00

abstract：:The increasing use of mobile phones by children and teenagers has raised concerns about their safety. Addressing such concerns is difficult, because no data are available on possible effects from long-term exposure to radiofrequency (RF) fields during the development of the nervous system. Possible morphological and f...

journal_title：Radiation research

authors： Kumlin T,Iivonen H,Miettinen P,Juvonen A,van Groen T,Puranen L,Pitkäaho R,Juutilainen J,Tanila H

更新日期：2007-10-01 00:00:00

abstract：:Evaluating the risk for central nervous system (CNS) effects after whole-body or partial-body irradiation presents challenges due in part to the varied exposure scenarios in the context of occupational, accidental or wartime releases. Risk estimations are further complicated by the fact that robust changes in brain fu...

journal_title：Radiation research

authors： Baddour AAD,Apodaca LA,Alikhani L,Lu C,Minasyan H,Batra RS,Acharya MM,Baulch JE

更新日期：2020-01-01 00:00:00

abstract：:The immunocytochemical response to DNA damage induced by low-energy bismuth and carbon ions was investigated in normal human fibroblasts. Inside the nuclei, the traversing charged particles lead to the accumulation of proteins related to DNA lesions and repair along the ion trajectories. Irradiation under a standard g...

journal_title：Radiation research

authors： Jakob B,Scholz M,Taucher-Scholz G

更新日期：2003-05-01 00:00:00

abstract：:Most plutonium-induced bone tumors in beagles arise in trabecular bone sites surrounded by hematopoietic tissue. The microvasculature and the relative incorporation of 241Pu (a low energy beta emitter) on trabecular bone surfaces from red and fatty marrow sites were studied in the adult beagle. The vascular volume, as...

journal_title：Radiation research

authors： Smith JM,Miller SC,Jee WS

更新日期：1984-08-01 00:00:00

abstract：:It has been suggested that fibrosis which develops after irradiation is caused by increases in vascular permeability. Plasma proteins leak into irradiated tissue where fibrinogen may be converted into fibrin which is gradually replaced by fibrous tissue. Vascular and fibrotic changes in mouse lung were investigated af...

journal_title：Radiation research

authors： Law MP

更新日期：1985-07-01 00:00:00

abstract：:Little computational or experimental information is available on site-specific hydroxyl attack probabilities to DNA. In this study, an atomistic stochastic model of OH radical reactions with DNA was developed to compute relative OH attack probabilities at individual deoxyribose hydrogen atoms. A model of the self-comp...

journal_title：Radiation research

authors： Aydogan B,Marshall DT,Swarts SG,Turner JE,Boone AJ,Richards NG,Bolch WE

更新日期：2002-01-01 00:00:00