Glucose-stimulated acidogenesis by Streptomyces peucetius.

Abstract:

:Cultures of Streptomyces peucetius often were observed to divert spontaneously from the production of anthracycline antibiotics to the excretion of acidic metabolites, whether grown in a defined medium or a nutrient-rich medium. The predominant excreted acidic metabolites were determined by high-performance liquid chromatography to be pyruvate and 2-oxoglutarate. The acidification occurred at high frequencies when glucose was the primary carbon source in a defined medium, at intermediate frequencies when fructose was the primary carbon source, and did not occur when either maltose, starch, or dextrin were used as primary carbon sources.

journal_name

Can J Microbiol

authors

Dekleva ML,Strohl WR

doi

10.1139/m87-198

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

1129-32

issue

12

eissn

0008-4166

issn

1480-3275

journal_volume

33

pub_type

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