Abstract:
:Successive determinations of serum total (T4) and free (FT4) thyroxine, total (T3) and free (FT3) 3,5,3'-triiodothyronine and total 3,3',5'-triiodothyronine (rT3) concentrations were performed by radioimmunoassay in 17 moderately obese women during a 6-week slimming cure. The 2.09 MJ/d (500 kcal/d) diet (50 per cent protein, 25 per cent carbohydrate and 25 per cent lipid) was given as three daily meals of general foods. During the cure, the body mass index (BMI) decreased by about 10 per cent, with a gradual decrease in the rate of weight loss. Moreover, the patients with the highest basal overweight had the largest subsequent weight loss. A decrease of about 15 per cent in serum T4 was observed from the second week to the end of the diet period. Inversely, serum FT4 increased transiently on day 3, then returned to the baseline. The fall in serum T3 and FT3 was obvious on day 3 and an approximate 20 per cent decrease in the two hormonal forms remained from the second to the last week of diet. Serum rT3 increased by 30 per cent during the first week, then returned to the baseline on the third week. The largest decreases in serum T4, T3 and FT3 observed during the cure occurred in the patients with the highest corresponding basal values. These findings suggest that (i) the rapid changes of the serum thyroid hormone concentrations observed during the slimming cure may be an adaptive mechanism against a further weight loss, and (ii) these changes would be related to the initial state of the thyroid hormone metabolism.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Chomard P,Vernhes G,Autissier N,Debry Gsubject
Has Abstractpub_date
1988-04-01 00:00:00pages
285-93issue
4eissn
0954-3007issn
1476-5640journal_volume
42pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:To objectively measure rates of breast-feeding to infants born in a baby-friendly hospital in Bangalore, India, and to capture home-based compliance to exclusive breastfeeding (EBF). SUBJECTS/METHODS:Breast-milk (BM) and non-breast-milk (NBM) water intake were assessed in 50 mother-infant pairs u...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.179
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To assess vitamin D status in women and their children aged 4-5 years in Northern Jordan during summer. DESIGN:A cross-sectional study in which 93 mother-child dyads volunteered through local community centers between June and July 2007. Anthropometric measurements were performed and information on socioecon...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.99
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To determine current practice in the delivery of parenteral nutrition (PN) in Australian hospitals. DESIGN:A cross-sectional mail survey. SETTING:Acute-care adult hospitals with greater than 200 beds in Australia. SUBJECTS:A total of 67 hospitals (65.7% response rate). INTERVENTION:Surveys were posted to ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602547
更新日期:2007-04-01 00:00:00
abstract::More than a decade has passed since it was unintentionally discovered that grapefruit juice interacts with certain drugs. The coadministration of these drugs with grapefruit juice can markedly elevate drug bioavailability, and can alter pharmacokinetic and pharmacodynamic parameters of the drug. The predominant mechan...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601736
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:This study investigated whether postprandial metabolic responses to bread could be lowered by substituting high amylose maize starch for a part of the flour. DESIGN AND SUBJECTS:Eight healthy subjects consumed test meals of equivalent nutritional composition based on white wheat bread, bread rich in amylose ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600718
更新日期:1999-05-01 00:00:00
abstract::The importance of processing conditions, product thickness and effect of egg addition for the glycaemic and hormonal responses to pasta was studied. Healthy subjects were given test meals with an equivalent amount of available carbohydrate from extruded high-temperature dried spaghetti and three varieties of fresh rol...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:There is a continuing need to examine the relationship between diet quality and health in the population. The Healthy Eating Index (HEI) has been developed as a composite measure of diet quality by the US Department of Agriculture. OBJECTIVES:The first objective was to use the HEI to assess the diet quality...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601989
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:A major goal of the European Food Information Resource (EuroFIR) Network of Excellence is to provide tools to overcome existing differences among member states and parties with respect to documentation and interchange of food composition data. Establishment of a common CEN (Comité Européen de Norm...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.210
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Body composition parameters are linked to cardio-metabolic risk. However, high-quality reference values of body composition are scarce, particularly in Asian population. The aim of study was to construct sex- and age-specific normative reference values of body composition for the Vietnamese population. METH...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00840-y
更新日期:2021-01-18 00:00:00
abstract:OBJECTIVES:To describe average levels of free-living energy expenditure in people from affluent societies and to determine the influence of body weight, height, age and sex. DESIGN:Analysis of 574 measurements of total energy expenditure (TEE, assessed by the doubly-labelled water method); basal metabolic rate (BMR, d...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To compare different possibilities of reporting the iodine supply in the same urine samples. Indeed, in field studies, urinary iodine concentration (I/L: micro g I/L, micro mol I/L, I/creatinine: micro g I/g creatanine, micro mol I/mol creatinine) is more readily available than excretion (I/24h micro g I/24 h...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601740
更新日期:2003-09-01 00:00:00
abstract::Traditional methods for estimating total body fat rely on the assumption that body fat distribution and bone mineral content are constant. However, in patients undergoing renal transplantation rapid changes in body composition occur, with variations in fat distribution and bone mineral content. In order to determine t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract::We conducted a mini-review of the literature, focusing on aging-related systemic inflammation and its association with vitamin D (VitD). As main findings, data indicate that inflammation in aging seems to have multiple origins, including immunosenescence, and from intestinal and adipose tissue, where VitD may modulate...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2016.177
更新日期:2017-04-01 00:00:00
abstract::The relationship between diet and attained height was studied in children and adolescents in Southern California. Diet pattern was determined from an extensive food frequency questionnaire in 1765 Caucasian children of 7-18 years, attending state schools (452 m and 443 f) and Seventh-day Adventist schools (427 m and 4...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To explore the relation between a wide range of alcohol consumptions and levels of the components of insulin-like growth factor system (IGFs) and adiponectin in humans. DESIGN:A cross-sectional study using controls from a case-control study on ovarian and endometrial cancer. SETTINGS:The study included wome...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602519
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601639
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations. METHODS:This study enrolled 100 healthy young adults aged 18-34 years. Ant...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2008.48
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The Dutch guidelines for a healthy diet aim to reduce major chronic diseases. However, supporting evidence on their overall association with all-cause and cause-specific mortality is limited. Recently, the Dutch Healthy Diet-index (DHD-index) has been developed to assess adherence to these guideli...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.163
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To explore incidence and prevalence rates of nutritional deficiency in adults in general practice. METHODS:Six Dutch general practice research and registration networks supplied incidence and prevalence rates of nutritional deficiency by the International Classification of Primary Care (ICPC) or 'E-list' lab...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602195
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:To compare dietary fat intake, the accuracy of individuals' awareness about their fat intake, and sociodemographic and psychosocial correlates of awareness, in Dutch and American samples of employed adults. A discrepancy between objective dietary intake data and subjective self-evaluation of dietary fat cons...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600442
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To study the relationship between consumption of milk and milk products, calcium, lactose and vitamin D and occurrence of colorectal cancers. DESIGN:Prospective cohort study. SUBJECTS:A total of 9959 men and women aged 15 y or older without history of cancer at baseline. During a 24 y follow-up, 72 new canc...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601260
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Quantitative ultrasound (QUS) is used to measure bone quality and is known to be safe, radiation free and relatively inexpensive compared with dual-energy X-ray absorptiometry (DXA) that is considered the gold standard for bone status assessments. However, there is no consensus regarding the valid...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.180
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The importance of both low-density lipoprotein cholesterol (LDLc) size and the apolipoprotein E (Apo E) in the atherogenic process is known, but there is little information with regard to the effect of phytosterols (PS) on these parameters. The aim of this study was to evaluate the influence of PS...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2010.241
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of dosage on the metabolic response to vegetables added to a mixed lunch meal, and to relate the amounts to the tripartite plate model. Carrots were chosen as an example, and the carrots were blanched, frozen and boiled to include possible effects of processing and cooking. The effects ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-06-01 00:00:00
abstract::This article was originally published under Nature Research's License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the article have been modified accordingly. ...
journal_title:European journal of clinical nutrition
pub_type: 已发布勘误
doi:10.1038/s41430-020-00776-3
更新日期:2020-10-15 00:00:00
abstract:OBJECTIVES:To stimulate novel sustainable solutions to the problem of the nutritional iron deficiency, we asked: How does Nature insure proper iron nutrition of embryos and neonatal animals? Estimates of iron deficiency world-wide are 30% of the population, with women and children at the greatest risk. Recent studies l...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The effect of a diet rich in monounsaturated fatty acids (MUFA) on blood pressure, glycemic control, lipids and insulin sensitivity was evaluated in women with gestational diabetes mellitus. DESIGN AND METHODS:A randomized, unpaired diet intervention was performed in 27 women with gestational diabetes mellit...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601193
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of cold storage and vinegar addition on glycaemic and insulinaemic responses to a potato meal in healthy subjects. SUBJECTS AND SETTING:A total of 13 healthy subjects volunteered for the study, and the tests were performed at Applied Nutrition and Food Chemistry, Lund University, S...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/sj.ejcn.1602238
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The term 'beer belly' expresses the common belief that beer consumption is a major determinant of waist circumference (WC). We studied the gender-specific associations between beer consumption and WC (partially in relation to body weight and hip circumference (HC) change). PARTICIPANTS/METHODS:Wi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.39
更新日期:2009-09-01 00:00:00
abstract::This study was conducted to follow up healthy subjects from a previous study (Warwick & Williams, 1987) in which favourable dietary changes were achieved during 1 week immediately after dietary advice but were accompanied by reduced energy intakes and weight loss. Twenty-one subjects (8m, 13f; 57 per cent of the origi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1988-05-01 00:00:00