Abstract:
OBJECTIVE:To explore the relation between a wide range of alcohol consumptions and levels of the components of insulin-like growth factor system (IGFs) and adiponectin in humans. DESIGN:A cross-sectional study using controls from a case-control study on ovarian and endometrial cancer. SETTINGS:The study included women hospitalized between 1999 and 2002 in Pordenone, Italy. SUBJECTS:One hundred and eight cancer-free (controls) with a median age of 61 years (range 29-79 years), admitted for acute conditions unrelated to gynecologic, hormonal or metabolic disorders or diseases leading to dietary modifications. INTERVENTIONS:Levels of IGF-I (total and free), total IGF-II, IGF-binding protein 1 (IGFBP-1), IGFBP-3 and adiponectin were individually measured, and their distributions across strata of alcohol consumption were tested by the Kruskal-Wallis statistic. RESULTS:Median concentrations of total IGF-I were higher (P<0.01) in women reporting low (151 ng/ml) or no alcohol consumption (134 ng/ml) compared to drinkers of 12-23 g/day (103 ng/ml) or >or=24 g/day (118 ng/ml). Median concentrations were higher (P=0.05) for IGFBP-3 in non-drinkers (2333 ng/ml) and in light drinkers (2647 ng/ml) compared to drinkers of >or=24 g/day (2090 ng/ml). No statistically significant difference emerged for other IGFs across levels of alcohol intakes. Adiponectin was slightly lower for non-drinkers, compared to all drinkers categories. CONCLUSIONS:Our study suggests that alcohol consumption is related to circulating levels of components of the IGF system and adiponectin. These results may have a potential impact on the prevention of several chronic diseases. SPONSORSHIP:Italian Association for Research on Cancer, Milan, Italy, and Italian League against Tumours, Milan, Italy.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Dal Maso L,La Vecchia C,Augustin LS,Mantzoros CS,Kendall CW,Franceschi Sdoi
10.1038/sj.ejcn.1602519subject
Has Abstractpub_date
2007-02-01 00:00:00pages
221-5issue
2eissn
0954-3007issn
1476-5640pii
1602519journal_volume
61pub_type
杂志文章abstract:OBJECTIVES:Pizza eating has been favourably related to the risk of cardiovascular disease, but the data are limited. To evaluate the potential role of pizza consumption on the risk of acute myocardial infarction (AMI), we considered data from an Italian study. DESIGN:We conducted a hospital-based case-control study on...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601997
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To study dietary lipid intake and plasma lipid profile of the Hong Kong Chinese population as part of a territory wide survey on cardiovascular risk factors. DESIGN:Randomised age and sex stratified survey. SUBJECTS:1010 subjects aged 25-74 y (500 men, 510 women). MEASUREMENTS:A food frequency method with ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600430
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations. METHODS:This study enrolled 100 healthy young adults aged 18-34 years. Ant...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2008.48
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the acceptance of a multinutrient liquid nutrition supplement in psycho-geriatric nursing home patients and the effect on weight, plasma nutrients and activities of daily life. DESIGN:Double-blind, placebo-controlled 12-week intervention study. SETTING:Two nursing homes in Boxtel, The Netherlan...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601319
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:To determine the content of glutamine in major food proteins. SUBJECTS/METHODS:We used a validated 131-food item food frequency questionnaire (FFQ) to identify the foods that contributed the most to protein intake among 70,356 women in the Nurses' Health Study (NHS, 1984). The content of glutamine and other...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.110
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Youth with type 1 diabetes (T1DM) are at substantially increased risk for adverse vascular outcomes, but little is known about the influence of dietary behavior on cardiovascular disease (CVD) risk profile. We aimed to identify dietary intake patterns associated with CVD risk factors and evaluate ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2014.96
更新日期:2014-12-01 00:00:00
abstract::Dietary energy restriction is the only proven method for extending lifespan and slowing aging in mammals, while maintaining health and vitality. Although the first experiments in this area were conducted over 60 y ago in rodents, possible applicability to primates has only been examined in controlled studies since 198...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601020
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There are positive associations between pulmonary function (PF) and fat-free mass as well as muscle strength. Contrarily, negative associations were found with indirect measures of visceral adipose tissue (VAT). We aimed to differentiate between associations of body composition and PF by assessing...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.146
更新日期:2017-03-01 00:00:00
abstract::This review outlines a hypothesis that A1 one of the common variants of beta-casein, a major protein in cows milk could facilitate the immunological processes that lead to type I diabetes (DM-I). It was subsequently suggested that A1 beta-casein may also be a risk factor for coronary heart disease (CHD), based on betw...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602104
更新日期:2005-05-01 00:00:00
abstract::This paper was based on collaborative research efforts from Wageningen University and the University Medical Centre St Radboud in The Netherlands and describes the rationale for web-based nutrition counselling applications in general practice as well as some of the frequently used models and theories (predominantly th...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602185
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:To estimate the intake of ruminant trans fatty acids (TFA) in the Danish population aged 1-80 years. DESIGN:Descriptive study. SUBJECTS:A sex- and age-stratified random sample drawn from the Danish Civil Registration System. A total of 3098 participants (51% female) aged 1-80 years were included. The partic...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602316
更新日期:2006-03-01 00:00:00
abstract::A comparison of two methods: analytical and calculation on an estimation of dietary intakes of nitrate and nitrite from six different types of general hospital diets was studied. Studies were performed in the winter season of 1996-1997. It was found that the mean daily intake of nitrates was 85 mg per person in the an...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600588
更新日期:1998-07-01 00:00:00
abstract::Alcohol-induced hypoglycaemia is a well-known phenomenon in insulin-treated diabetic subjects. Less attention has been paid to the impact of alcohol on blood glucose and insulin responses in non-insulin dependent diabetic subjects. The aim of this study was to investigate the acute metabolic effects of different alcoh...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:To investigate the relation between maternal smoking habits, plasma lipids and milk fatty acid (FA) content and composition. DESIGN:Breastfeeding mothers who gave birth to healthy, full-term infants were recruited. Mothers were interviewed on smoking habits, being defined smokers (S) when usually smoking at ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601711
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is increasing evidence to support that a high-protein diet may promote weight loss and prevent weight (re)gain better than a low-protein diet, and that the effect is due to higher diet-induced thermogenesis (DIT) and increased satiety. However, data on the effect of different types of protei...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2011.221
更新日期:2012-05-01 00:00:00
abstract::Diet may both increase and decrease oxidative stress in the body. We compared the effects of four strictly controlled isocaloric diets with different intakes of polyunsaturated fatty acids (PUFA, 11 or 3% of energy) and vegetables and fruit (total amount of vegetables and fruit 516 or 1059 g/10 MJ) on markers associat...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/sj.ejcn.1602865
更新日期:2008-09-01 00:00:00
abstract::Recent recognition of the early onset and high prevalence of wasting (30%) and stunting (20%) among infants 0-5 months in India draws attention to the need to understand the causes and develop prevention strategies. Such growth failure has dire consequences in the short (increased mortality) and long-term (loss of hum...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2013.18
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:There is evidence linking oral propionate to a reduction in food intake, which could confer functional food properties in the fight against obesity. However, propionate is typically volatile with a pungent smell and taste and so incorporating into foods naturally, at levels acceptable to the consumer is a no...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2012.1
更新日期:2012-07-01 00:00:00
abstract::The diet of many athletes is inadequate due to overly restrictive habits and an obsession with losing weight in order to maintain a particular level of body weight. Many female athletes, particularly those who participate in sports that emphasize leanness (gymnastics, distance running, diving, figure skating and class...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601483
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:Reproducible and valid methods for measuring fruit and vegetable consumption among young school children are urgently needed. The aim of this study was to test the reproducibility and the validity of a newly developed questionnaire on the intake of fruit and vegetable among Norwegian 6th graders. The question...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601875
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Fiber-rich diets have been proposed to lower circulating levels of inflammatory makers. Our objective was to investigate cross-sectional relationships between fiber intake and plasma fibrinogen. SUBJECTS/METHODS:We examined the relationship between plasma fibrinogen and dietary fiber in 20,960 me...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.194
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Living in socioeconomically disadvantaged neighbourhoods is associated with increased risk of a poor diet; however, the mechanisms underlying associations are not well understood. This study investigated whether selected healthy and unhealthy dietary behaviours are patterned by neighbourhood-socio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.174
更新日期:2010-12-01 00:00:00
abstract::High serum antioxidant vitamins are increasingly being associated with reduced risk of coronary heart disease (CHD). Previous studies have not addressed the relationship between dietary antioxidant vitamins and risk of CHD although diet is a key factor which modifies blood antioxidant vitamin levels. In prospective st...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract:OBJECTIVE:To assess the usefulness of fat-free mass (FFM) as an index of total body protein (TBPr) status in continuous ambulatory peritoneal dialysis (CAPD) patients. DESIGN:TBPr was measured by in vivo neutron activation analysis (IVNAA) and expressed as a standardised protein index (PI). FFM was estimated by dual e...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Changes in plasma insulin and glucose concentrations before and after feeding were measured in six female subjects (post-obese) who had regained a normal body mass after a history of severe obesity (mean weight loss, 37.1 +/- 2.6 kg). The responses of the post-obese group were compared with a group of weight- and age-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVES:To study the joint association of coffee consumption and serum gamma-glutamyltransferase (GGT) levels on the risk of developing type II diabetes. DESIGN, SETTING AND SUBJECTS:A total of 21,826 Finnish men and women who were 35-74 years of age and without any history of diabetes at baseline (years 1982, 1987...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602712
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To assess the effect of zinc supplementation on respiratory tract disease, immunity and growth in malnourished children. DESIGN:A randomized double-blind placebo-controlled trial. SETTING:A day-care center in Quito, Ecuador. SUBJECTS:Fifty children (12-59 months old) recruited by height-for-age and weight-...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-01-01 00:00:00
abstract::Hypothalamic amenorrhoea has been shown to be associated with hypercarotenaemia, but no causal link has been established. Many people are unaware of the health implications of carotenoderma. We report on a 36-year-old woman with normal body mass index and with a history of secondary amenorrhoea for 2 years and caroten...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.128
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:To identify the types and quantities of 'extra' foods, or energy-dense, nutrient-poor foods, consumed by Australian adults, and assess their contribution to total energy and nutrient intakes. SUBJECT/METHODS:We used 24-h recall data from 10 851 adults, aged 19 years and over, who participated in the nationa...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2008.51
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To determine the effect of iron supplementation on iron status and endurance capacity. DESIGN:Randomized, double-blind iron supplementation. SETTING:University of Missouri-Columbia and surrounding community. SUBJECTS:Twenty iron-deficient (serum ferritin, sFer<16 microg/l; serum transferrin receptor, sTfR>...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602479
更新日期:2007-01-01 00:00:00