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Bone status measured by quantitative ultrasound: a comparison with DXA in Thai children.

Abstract：

BACKGROUND/OBJECTIVES:Quantitative ultrasound (QUS) is used to measure bone quality and is known to be safe, radiation free and relatively inexpensive compared with dual-energy X-ray absorptiometry (DXA) that is considered the gold standard for bone status assessments. However, there is no consensus regarding the validity of QUS for measuring bone status. The aim of this study was to compare QUS and DXA in assessing bone status in Thai children. SUBJECTS/METHODS:A total of 181 Thai children (90 boys and 91 girls) aged 6 to 12 years were recruited. Bone status was measured by two different techniques in terms of the speed of sound (SOS) using QUS and bone mineral density (BMD) using DXA. Calcium intake was assessed by 24 h diet recall. Pearson's correlation, κ-statistic and Bland and Altman analysis were used to assess the agreement between the methods. RESULTS:There was no correlation between the two different techniques. Mean difference (s.d.) of the Z-scores of BMD and SOS was -0.61 (1.27) that was different from zero (P<0.05). Tertiles of Z-scores of BMD and QUS showed low agreement (κ 0.022, P=0.677) and the limits of agreement in Bland and Altman statistics were wide. CONCLUSIONS:Although QUS is easy and convenient to use, the SOS measurements at the radius seem not appropriate for assessing bone quality status.

journal_name

Eur J Clin Nutr

journal_title

European journal of clinical nutrition

authors

Srichan W,Thasanasuwan W,Kijboonchoo K,Rojroongwasinkul N,Wimonpeerapattana W,Khouw I,Deurenberg P

doi

10.1038/ejcn.2015.180

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

894-7

issue

8

eissn

0954-3007

issn

1476-5640

pii

ejcn2015180

journal_volume

70

pub_type

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