Abstract:
:Torque teno (TT) viruses have been more frequently reported in malignant biopsies when compared to normal control tissue. The possible contribution of TT virus infection to human carcinogenesis or the potential oncolytic functions of these virus infections are being discussed based on available experimental evidence. The data could suggest an involvement of TT virus infections as an indirect carcinogen by modulating T cell immune responses. Significant oncolytic functions, potentially mediated by the inhibition of nuclear factor (NF)-kappaB transcription factor or by apoptin-like gene activities, are emerging to be less likely.
journal_name
Curr Top Microbiol Immunoljournal_title
Current topics in microbiology and immunologyauthors
zur Hausen H,de Villiers EMdoi
10.1007/978-3-540-70972-5_7subject
Has Abstractpub_date
2009-01-01 00:00:00pages
109-16eissn
0070-217Xissn
2196-9965journal_volume
331pub_type
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