TT viruses: oncogenic or tumor-suppressive properties?

Abstract:

:Torque teno (TT) viruses have been more frequently reported in malignant biopsies when compared to normal control tissue. The possible contribution of TT virus infection to human carcinogenesis or the potential oncolytic functions of these virus infections are being discussed based on available experimental evidence. The data could suggest an involvement of TT virus infections as an indirect carcinogen by modulating T cell immune responses. Significant oncolytic functions, potentially mediated by the inhibition of nuclear factor (NF)-kappaB transcription factor or by apoptin-like gene activities, are emerging to be less likely.

authors

zur Hausen H,de Villiers EM

doi

10.1007/978-3-540-70972-5_7

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

109-16

eissn

0070-217X

issn

2196-9965

journal_volume

331

pub_type

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