Abstract:
BACKGROUND:Differences in the neighborhood food environment may contribute to disparities in obesity. OBJECTIVES:The purpose of this study was to examine the association of neighborhood food environments with body mass index (BMI) and obesity after control for neighborhood walkability. METHODS:This study employed a cross-sectional, multilevel analysis of BMI and obesity among 13,102 adult residents of New York City. We constructed measures of the food environment and walkability for the neighborhood, defined as a half-mile buffer around the study subject's home address. RESULTS:Density of BMI-healthy food outlets (supermarkets, fruit and vegetable markets, and natural food stores) was inversely associated with BMI. Mean adjusted BMI was similar in the first two quintiles of healthy food density (0 and 1.13 stores/km2, respectively), but declined across the three higher quintiles and was 0.80 units lower [95% confidence interval (CI), 0.27-1.32] in the fifth quintile (10.98 stores/km2) than in the first. The prevalence ratio for obesity comparing the fifth quintile of healthy food density with the lowest two quintiles combined was 0.87 (95% CI, 0.78-0.97). These associations remained after control for two neighborhood walkability measures, population density and land-use mix. The prevalence ratio for obesity for the fourth versus first quartile of population density was 0.84 (95% CI, 0.73-0.96) and for land-use mix was 0.91 (95% CI, 0.86-0.97). Increasing density of food outlets categorized as BMI-unhealthy was not significantly associated with BMI or obesity. CONCLUSIONS:Access to BMI-healthy food stores is associated with lower BMI and lower prevalence of obesity.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Rundle A,Neckerman KM,Freeman L,Lovasi GS,Purciel M,Quinn J,Richards C,Sircar N,Weiss Cdoi
10.1289/ehp.11590subject
Has Abstractpub_date
2009-03-01 00:00:00pages
442-7issue
3eissn
0091-6765issn
1552-9924journal_volume
117pub_type
杂志文章abstract::In this paper we report yields, identities, and mutagenicities of products from heating a polycyclic aromatic hydrocarbon (PAH)-contaminated, Superfund-related synthetic soil matrix without exogenous oxygen. We heated batch samples of soil pretreated with 5.08 wt% (by weight) pyrene in a tubular furnace under a consta...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.00108709
更新日期:2000-08-01 00:00:00
abstract::Most contemporary bioinsecticides are derived from scaled-up cultures of Bacillus thuringiensis subspecies israelensis (Bti) and kurstaki (Btk), whose particulate fractions contain mostly B. thuringiensis spores (> 10(12)/L) and proteinaceous aggregates, including crystal-like parasporal inclusion bodies (PIB). Based ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.00108919
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. OBJECTIVE:We aimed to assess the toxicity of well-characte...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.0800121
更新日期:2009-04-01 00:00:00
abstract::An estimated 8000 children 0 to 14 years of age are diagnosed annually with cancer in the United States. Leukemia and brain tumors are the most common childhood malignancies, accounting for 30 and 20% of newly diagnosed cases, respectively. From 1975 to 1978 to 1987 to 1990, cancer among white children increased sligh...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.95103s6177
更新日期:1995-09-01 00:00:00
abstract::Human fibroblasts (HFW) were 10-fold more susceptible than Chinese hamster ovary (CHO-K1) cells to sodium arsenite. Comparison of cellular antioxidant enzyme activities showed that CHO-K1 cells contained 3- and 8-fold more glutathione-peroxidase and catalase activities, respectively, than HFW cells. Since vitamin E, m...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.94102s3101
更新日期:1994-09-01 00:00:00
abstract::Spatial epidemiology is the description and analysis of geographic variations in disease with respect to demographic, environmental, behavioral, socioeconomic, genetic, and infectious risk factors. We focus on small-area analyses, encompassing disease mapping, geographic correlation studies, disease clusters, and clus...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.6735
更新日期:2004-06-01 00:00:00
abstract::The Thomsen-Friedenreich antigen (Gal-GalNAc) represents a tumor-associated molecule, which is assumed to be one of the few chemically well-defined antigens with a proven association with malignancy. In order to analyze the role of the carbohydrate structure Gal-GalNAc for gastrointestinal tumors, we immunized Balb/c ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9088255
更新日期:1990-08-01 00:00:00
abstract::In recent years there have been a significant number of publications on the benefits and challenges of community-based participatory research (CBPR). In this introduction we give an overview of three projects presented in this mini-monograph and highlight their commonalities and differences in developing community-uni...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7911
更新日期:2005-12-01 00:00:00
abstract::Carcinogenic nickel compounds are usually found to be weak mutagens; therefore these compounds may not exert their carcinogenic activity through conventional genotoxic mechanisms. On the other hand, the activities of many nickel compounds have not been adequately investigated. We evaluated the genotoxic activities of ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.94102s973
更新日期:1994-11-01 00:00:00
abstract::Biological markers of intermediate health outcomes sometimes provide a superior alternative to traditional measures of pollutant-related disease. Some opportunities and methodologic issues associated with using markers are discussed in the context of exposures to four complex mixtures: environmental tobacco smoke and ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.93101s4193
更新日期:1993-12-01 00:00:00
abstract::Organophosphates in increasing amounts and wider varieties of molecular structure are being used to replace the organochlorine pesticides. It has been assumed that the organophosphates as a class would have a minimal chronic toxicity due to rapid hydrolysis and an unfavorable partitioning as regards to lipids. The phy...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.761377
更新日期:1976-02-01 00:00:00
abstract::Biomedical developments in the 21st century provide an unprecedented opportunity to gain a dynamic systems-level and human-specific understanding of the causes and pathophysiologies of disease. This understanding is a vital need, in view of continuing failures in health research, drug discovery, and clinical translati...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1510345
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease (CVD) affects 71 million American adults and remains the leading cause of death in the United States and Europe. Despite studies that suggest that the development of CVD may be linked to intrauterine growth or early events in childhood, little direct experimental evidence supports the ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.0800193
更新日期:2009-07-01 00:00:00
abstract::While the rat pancreas is susceptible to experimental cancer induction, the spontaneous incidence of pancreatic cancer in this species is reported to be very low. However, we observed unusually high incidences of focal acinar hyperplasia and acinar adenoma in vehicle control male F344/N rats of some NCI/NTP 2-year tox...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8456213
更新日期:1984-06-01 00:00:00
abstract::This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.93101s281
更新日期:1993-07-01 00:00:00
abstract::The phenylphosphonothioate insecticides EPN and leptophos, and several analogs, were evaluated with respect to their delayed neurotoxic effects in hens and their environmental behavior in a terrestrial-aquatic model ecosystem. Acute toxicity to insects was highly correlated with sigma sigma of the substituted phenyl g...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8036187
更新日期:1980-06-01 00:00:00
abstract::Syrian hamster embryo cells were treated with galactose oxidase, followed by reduction with tritiated sodium borohydride at pH 7.4. The labeling patterns of galactosyl and N-acetyl galactosaminyl residues on the cell surface were altered in comparing scraped vs. unscraped and buffer vs. media-soaked cells treated with...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8034103
更新日期:1980-02-01 00:00:00
abstract::Recent studies show that young children can be exposed to pesticides during normal oral exploration of their environment and their level of dermal contact with floors and other surfaces. Children living in agricultural areas may be exposed to higher pesticide levels than other children because of pesticides tracked in...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.99107s3409
更新日期:1999-06-01 00:00:00
abstract::Until recently, mutagenicity testing was done on preselected compounds in a manner in which the testing laboratories knew the identity of the substances under test and the "expected" results, i.e., positive for compounds selected because of their carcinogenicity and negative for food additives. There is no completed s...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7720253
更新日期:1977-10-01 00:00:00
abstract::In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland dur...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.01109s5711
更新日期:2001-10-01 00:00:00
abstract::There is a need to identify specific biological indicator(s) of cadmium exposure so that the renal damage can be prevented. Towards this end, we have examined the usefulness of urinary metallothionein as an indicator of cadmium body burden. It is found that, in both animals and humans, urinary metallothionein level is...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8454171
更新日期:1984-03-01 00:00:00
abstract::Recent investigations have demonstrated the ability of leukocytes to metabolize promutagens or procarcinogens into their genotoxic forms. As a possible explanation for the association between inflammation and cancer, we and others have hypothesized that local accumulations of leukocytes could take up nearby promutagen...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.93101s327
更新日期:1993-10-01 00:00:00
abstract::The lymphocyte micronucleus assay was used to measure the average frequency of micronuclei in a population and thus assess genotoxic effects. Data from 174 persons give an average value of 16.4 +/- 7.3, and a slight age-dependence was observed. To detect combined environmental mutagen injuries the micronucleus assay w...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.101-1521140
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVES:According to the 2007 National Research Council report Toxicology for the Twenty-First Century, modern methods (e.g., "omics," in vitro assays, high-throughput testing, computational methods) will lead to the emergence of a new approach to toxicology. The Salmonella mammalian microsome mutagenicity assay has...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.1002336
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Biomass smoke is an important source of particulate matter (PM), and much remains to be discovered with respect to the human health effects associated with this specific PM source. Exposure to biomass smoke can occur in one of two main categories: short-term exposures consist of periodic, seasonal exposures ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.11378
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The toxicity of many xenobiotic compounds is believed to involve oxidative injury to cells. Direct assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achievable. Development of genetically encoded probes designed for monitoring intracellular redox changes represent...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1206039
更新日期:2013-03-01 00:00:00
abstract::A review of the experimental studies relating boron to biological effects on appendicular and axial bones in animal models suggests that numerous influences, known and unknown, affect the responsiveness of bone to dietary boron. Degrees of skeletal response to boron are modified by other nutritional variables that inc...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.94102s749
更新日期:1994-11-01 00:00:00
abstract::The knowledge of specific problems of occupational cancer in Spain is scarce. The environment of the workplace has improved over the last few years after a long period distinguished by bad working conditions, incomplete legislation, and insufficient safety measures and control. It has been estimated that 3,083,479 wor...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.107-1566267
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Concern persists over endocrine-disrupting effects of persistent organic pollutants (POPs) on human growth and sexual maturation. Potential effects of toxicant exposures on testosterone levels during puberty are not well characterized. OBJECTIVES:In this study we evaluated the relationship between toxicants...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1205984
更新日期:2014-03-01 00:00:00
abstract::The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...
journal_title:Environmental health perspectives
pub_type:
doi:10.1289/ehp.isee2014
更新日期:2014-10-30 00:00:00