Childhood cancer: overview of incidence trends and environmental carcinogens.

abstract：:Hamsters were exposed to an aerosol of fused aluminosilicate particles (FAP) labeled with 57Co. Three groups of animals were given bronchopulmonary lavage, beginning at either 1 week, 1 month, or 6 months after exposure. Each treated group was lavaged eight times over a period of 25 days. Each lavage involved 10 salin...

journal_title：Environmental health perspectives

authors： Ellender M,Hodgson A,Wood KL,Moody JC

更新日期：1992-07-01 00:00:00

abstract：:Environmental tobacco smoke (ETS) has been associated with cardiovascular mortality. Pathophysiologic pathways leading from ETS exposure to cardiopulmonary disease are still being explored. Reduced cardiac autonomic function, as measured by heart rate variability (HRV), has been associated with cardiac vulnerability a...

journal_title：Environmental health perspectives

authors： Pope CA 3rd,Eatough DJ,Gold DR,Pang Y,Nielsen KR,Nath P,Verrier RL,Kanner RE

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

journal_title：Environmental health perspectives

authors： Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

更新日期：2018-04-26 00:00:00

abstract：:In an attempt to elucidate the relationship between DNA adduct formation and tumorigenesis, DNA adducts were measured in the livers and bladders of mice during chronic exposure to several different doses of 2-acetylaminofluorene (2-AAF) and 4-aminobiphenyl (4-ABP). Continuous oral administration of these compounds for...

journal_title：Environmental health perspectives

authors： Poirier MC,Beland FA

更新日期：1994-10-01 00:00:00

abstract：:New technologies are providing innovative ways to reduce sound levels in many areas. Aircraft engineers are finding ways to reduce the noise produced by jet engines, while road builders are using rubber-enhanced pavement to quiet highway noise. Indoor acoustics are benefiting from materials that transform sound waves ...

journal_title：Environmental health perspectives

authors： Manuel J

更新日期：2005-01-01 00:00:00

abstract：:Risk assessment is a process often divided into the following steps: a) hazard identification, b) dose-response assessment, c) exposure assessment, and d) risk characterization. Regulatory toxicity studies usually are aimed at providing data for the first two steps. Human case reports, environmental research, and in v...

journal_title：Environmental health perspectives

authors： Harry GJ,Billingsley M,Bruinink A,Campbell IL,Classen W,Dorman DC,Galli C,Ray D,Smith RA,Tilson HA

更新日期：1998-02-01 00:00:00

abstract：:This paper reports the results of a comprehensive survey of the effects of the accidental release of radiation caused by the accident at the Chernobyl nuclear power station in April 1986. The accident and the resulting release of radiation and radioactive products into the atmosphere produced the most serious environm...

journal_title：Environmental health perspectives

authors： Kulakov VI,Sokur TN,Volobuev AI,Tzibulskaya IS,Malisheva VA,Zikin BI,Ezova LC,Belyaeva LA,Bonartzev PD,Speranskaya NV

更新日期：1993-07-01 00:00:00

abstract：:Idiopathic Parkinson's disease (IPD) represents a common neurodegenerative disorder. An estimated 2% of the U.S. population, age 65 and older, develops IPD. The number of IPD patients will certainly increase over the next several decades as the baby-boomers gradually step into this high-risk age group, concomitant wit...

journal_title：Environmental health perspectives

authors： Aschner M

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...

journal_title：Environmental health perspectives

authors： Pyko A,Eriksson C,Lind T,Mitkovskaya N,Wallas A,Ögren M,Östenson CG,Pershagen G

更新日期：2017-11-20 00:00:00

abstract：BACKGROUND:Genetics may partially explain observed heterogeneity in associations between traffic-related air pollution and incident asthma. OBJECTIVE:Our aim was to investigate the impact of gene variants associated with oxidative stress and inflammation on associations between air pollution and incident childhood ast...

journal_title：Environmental health perspectives

authors： MacIntyre EA,Brauer M,Melén E,Bauer CP,Bauer M,Berdel D,Bergström A,Brunekreef B,Chan-Yeung M,Klümper C,Fuertes E,Gehring U,Gref A,Heinrich J,Herbarth O,Kerkhof M,Koppelman GH,Kozyrskyj AL,Pershagen G,Postma DS,Th

更新日期：2014-04-01 00:00:00

abstract：:An association between human illness and exposure to Pfiesteria was first observed among laboratory personnel working with the microorganism. In 1997, in the setting of Pfiesteria activity on the Pocomoke River in Maryland, difficulties with learning and memory were epidemiologically associated with high-level exposur...

journal_title：Environmental health perspectives

authors： Morris JG Jr

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Health risks differ by fine particle (aerodynamic diameter ≤ 2.5 μm) component, although with substantial variability. Traditional methods to assess component-specific risks are limited, suggesting the need for alternative methods. OBJECTIVES:We examined whether the odds of daily hospital admissions differ ...

journal_title：Environmental health perspectives

authors： Suh HH,Zanobetti A,Schwartz J,Coull BA

更新日期：2011-10-01 00:00:00

abstract：:Because of rampant concern that estrogenic chemicals in the environment may be adversely affecting the health of humans and wildlife, reliable methods for detecting and characterizing estrogenic chemicals are needed. It is important that general agreement be reached on which tests to use and that these tests then be a...

journal_title：Environmental health perspectives

authors： Shelby MD,Newbold RR,Tully DB,Chae K,Davis VL

更新日期：1996-12-01 00:00:00

abstract：SUMMARY:From climate change to hydraulic fracturing, and from drinking water safety to wildfires, environmental challenges are changing. The United States has made substantial environmental protection progress based on media-specific and single pollutant risk-based frameworks. However, today’s environmental problems ar...

journal_title：Environmental health perspectives

authors： Burke TA,Cascio WE,Costa DL,Deener K,Fontaine TD,Fulk FA,Jackson LE,Munns WR,Orme-Zavaleta J,Slimak MW,Zartarian VG

更新日期：2017-03-01 00:00:00

abstract：:A system suitable for the detection of meiotic aneuploidy is described in which various different origins of the aneuploidy can be distinguished. Aneuploid meiotic products are detected as black disomic spores held in asci containing all the products of a single meiosis. Aneuploidy may result from nondisjunction or fr...

journal_title：Environmental health perspectives

authors： Bond DJ,McMillan L

更新日期：1979-08-01 00:00:00

abstract：:The neurochemical basis of memory has been approached experimentally in four different ways: the bioassay; the interventive approach; the interventive-correlative approach; and the correlative approach. These approaches are fundamentally similar to those used for the study of the chemistry of any behavior. Each of the...

journal_title：Environmental health perspectives

authors： Dunn AJ

更新日期：1978-10-01 00:00:00

abstract：:Multiple factors, known and unknown, contribute to human breast cancer. Hereditary, hormonal, and reproductive factors are associated with risk of breast cancer. Environmental agents, including chemical carcinogens, are modifiable risk factors to which over 70% of breast cancers have been attributed. Polymorphisms of ...

journal_title：Environmental health perspectives

authors： DeBruin LS,Josephy PD

更新日期：2002-02-01 00:00:00

abstract：:The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...

journal_title：Environmental health perspectives

authors：

更新日期：2014-10-30 00:00:00

abstract：:We present a case of a diamond polisher who developed occupational asthma as a result of prolonged exposure to various potent and well-recognized asthma-inducing agents, including cobalt dust. Although the patient was seen by various medical professionals during the initial course of his illness and given an early dia...

journal_title：Environmental health perspectives

authors： Wilk-Rivard E,Szeinuk J

更新日期：2001-12-01 00:00:00

abstract：:Lead encephalopathy was induced in developing Long-Evans rats by adding lead carbonate (4% w/w) to the diet of nursing mother immediately after delivery. The morphological and biochemical features of cerebral ontogenesis were studied in 30-day-old rats. By the 30th postnatal day, the overall effect of lead intoxicatio...

journal_title：Environmental health perspectives

authors： Krigman MR,Hogan EL

更新日期：1974-05-01 00:00:00

abstract：:High cadmium exposure is known to cause bone damage, but the association between low-level cadmium exposure and osteoporosis remains to be clarified. Using a population-based women's health survey in southern Sweden [Women's Health in the Lund Area (WHILA) ] with no known historical cadmium contamination, we investiga...

journal_title：Environmental health perspectives

authors： Akesson A,Bjellerup P,Lundh T,Lidfeldt J,Nerbrand C,Samsioe G,Skerfving S,Vahter M

更新日期：2006-06-01 00:00:00

abstract：:The purpose of this study was to examine whether perinatal exposure to two major environmental endocrine-disrupting chemicals, bisphenol A (BPA; 0.1 mg/kg/day orally) and nonylphenol [NP; 0.1 mg/kg/day (low dose) and 10 mg/kg/day (high dose) orally] daily from gestational day 3 to postnatal day 20 (transplacental and ...

journal_title：Environmental health perspectives

authors： Negishi T,Kawasaki K,Suzaki S,Maeda H,Ishii Y,Kyuwa S,Kuroda Y,Yoshikawa Y

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Numerous man-made pollutants activate the aryl hydrocarbon receptor (AhR) and are risk factors for type 2 diabetes. AhR signaling also affects molecular clock genes to influence glucose metabolism. OBJECTIVE:We investigated mechanisms by which AhR activation affects glucose metabolism. METHODS:Glucose tole...

journal_title：Environmental health perspectives

authors： Wang C,Xu CX,Krager SL,Bottum KM,Liao DF,Tischkau SA

更新日期：2011-12-01 00:00:00

abstract：:Human DNA adduct formation (covalent modification of DNA with chemical carcinogens) is a promising biomarker for elucidating the molecular epidemiology of cancer. Classes of compounds for which human DNA adducts have been observed include polycyclic aromatic hydrocarbons (PAHs), nitrosamines, mycotoxins, aromatic amin...

journal_title：Environmental health perspectives

authors： Poirier MC,Weston A

更新日期：1996-10-01 00:00:00

abstract：:We examined the estrogenicity of binary mixtures of the hydroxylated polychlorinated biphenyls (OHPCBs) 2,4,6-trichloro-4'-biphenylol (2,4,6-TCB-4'-OH) and 2,3,4,5-tetrachloro-4'-biphenylol and the pesticides endosulfan and dieldrin. The OHPCBs and pesticides were tested in both the MCF-7 focus assay and a competitive...

journal_title：Environmental health perspectives

authors： Arcaro KF,Vakharia DD,Yang Y,Gierthy JF

更新日期：1998-08-01 00:00:00

abstract：:Implementation of the Toxic Substances Control Act of 1977 creates the need to reliably establish testing priorities because laboratory resources are limited and the number of industrial chemicals requiring evaluation is overwhelming. The use of quantitative structure activity relationship (QSAR) models as rapid and p...

journal_title：Environmental health perspectives

authors： McKim JM,Bradbury SP,Niemi GJ

更新日期：1987-04-01 00:00:00

abstract：:The natural occurrence of palladium (Pd) is rare. It is obtained as a by-product during the extraction of platinum and, until the present time, its uses were small in number--principally in the manufacture of jewelry, dental alloys, chemical catalysts, and electrical contacts. Interest in Pd toxicology has been limite...

journal_title：Environmental health perspectives

authors： Wiester MJ

更新日期：1975-12-01 00:00:00

abstract：:This paper examines behavioral changes in natural populations of wildlife associated with pollution. Although some changes such as lack of nest attentiveness and decreased nest defense have been noted, the results have not been consistent and have been difficult to relate to specific pollutants. Experimental studies i...

journal_title：Environmental health perspectives

authors： Peakall DB

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Persistent organic pollutants (POPs) are developmental toxicants, but the impact of both maternal and paternal exposures on offspring birth size is largely unexplored. OBJECTIVE:We examined associations between maternal and paternal serum concentrations of 63 POPs, comprising five major classes of pollutant...

journal_title：Environmental health perspectives

authors： Robledo CA,Yeung E,Mendola P,Sundaram R,Maisog J,Sweeney AM,Barr DB,Louis GM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Evidence indicates that air pollution contributes to cardiopulmonary mortality. There is ongoing debate regarding the size and shape of the pollution–mortality exposure–response relationship. There are also growing appeals for estimates of pollution–mortality relationships that use public data and are based ...

journal_title：Environmental health perspectives

authors： Pope CA 3rd,Lefler JS,Ezzati M,Higbee JD,Marshall JD,Kim SY,Bechle M,Gilliat KS,Vernon SE,Robinson AL,Burnett RT

更新日期：2019-07-01 00:00:00