Female reproductive function in areas affected by radiation after the Chernobyl power station accident.


:This paper reports the results of a comprehensive survey of the effects of the accidental release of radiation caused by the accident at the Chernobyl nuclear power station in April 1986. The accident and the resulting release of radiation and radioactive products into the atmosphere produced the most serious environmental contamination so far recorded. We have concentrated on evaluating the outcomes and health risks to women, their reproductive situation, and consequences for their progeny. We have concentrated on two well-defined areas: the Chechersky district of the Gomel region in Belorussia and the Polessky district of the Kiev region in the Ukraine. A number of investigations were carried out on 688 pregnant women and their babies, and data were obtained from 7000 labor histories of the development of newborns for a period of 8 years (3 years before the accident and 5 years after it). Parameters examined included birth rate, thyroid pathology, extragenital pathology such as anemias, renal disorders, hypertension, and abnormalities in the metabolism of fats, complications of gestation, spontaneous abortions, premature deliveries, perinatal morbidity and mortality, stillbirths and early neonatal mortality, infections and inflammatory diseases, neurological symptoms and hemic disturbances in both mothers and infants, trophic anomalies, and biochemical and structural changes in the placenta. Several exogenous, complicating influences were also considered such as psycho-emotional factors, stress, lifestyle changes, and others caused directly by the hazardous situation and by its consequences such as treatment, removal from affected areas, etc.(ABSTRACT TRUNCATED AT 250 WORDS)


Kulakov VI,Sokur TN,Volobuev AI,Tzibulskaya IS,Malisheva VA,Zikin BI,Ezova LC,Belyaeva LA,Bonartzev PD,Speranskaya NV




Has Abstract,Author List Incomplete


1993-07-01 00:00:00








101 Suppl 2


  • Dose-dependent fate of vinyl chloride and its possible relationship to oncogenicity in rats.

    abstract::Studies on the fate of 14C-labeled vinyl chloride (VC) following oral administration and inhalation exposure in rats demonstrated that the disposition of VC in the body is a function of the dose. More importantly, from the data available, it appears that a correlation exists between doses of VC which cause tumors and ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Watanabe PG,Gehring PJ

    更新日期:1976-10-01 00:00:00

  • Metabolic activation and lung toxicity: a basis for cell-selective pulmonary damage by foreign chemicals.

    abstract::The lungs may be exposed to potentially toxic metabolites that are either formed in situ or which are present in the circulation. Therefore, pulmonary injury may be a prominent effect of certain classes of chemicals that undergo bioactivation in the body. The specific types of lung cells damaged may depend upon factor...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Boyd MR

    更新日期:1984-04-01 00:00:00

  • Magnetic fields and cancer: animal and cellular evidence--an overview.

    abstract::A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different init...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Holmberg B

    更新日期:1995-03-01 00:00:00

  • Dietary exposure to PCBs and dioxins.

    abstract::comments on S. Patandin et al. : Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long-term exposure. Environ Health Perspect 107:45-51 (1999). ...

    journal_title:Environmental health perspectives

    pub_type: 评论,信件


    authors: LaKind JS,Filser JG

    更新日期:1999-10-01 00:00:00

  • Persistence of long, thin chrysotile asbestos fibers in the lungs of rats.

    abstract::The distribution of inhaled mineral fibers in the lung determines the site and severity of disease caused by the fibers. Some of our recent work has described the fate of inhaled asbestos fibers in rodents. After a brief inhalation exposure, asbestos fibers are deposited primarily at the first alveolar duct bifurcatio...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Coin PG,Roggli VL,Brody AR

    更新日期:1994-10-01 00:00:00

  • Studying health outcomes in farmworker populations exposed to pesticides.

    abstract::A major goal of studying farmworkers is to better understand how their work environment, including exposure to pesticides, affects their health. Although a number of health conditions have been associated with pesticide exposure, clear linkages have yet to be made between exposure and health effects except in cases of...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: McCauley LA,Anger WK,Keifer M,Langley R,Robson MG,Rohlman D

    更新日期:2006-06-01 00:00:00

  • Formation and persistence of 8-oxoguanine in rat lung cells as an important determinant for tumor formation following particle exposure.

    abstract::Exposure of rats to quartz (or various other particles) can lead to the development of lung tumors. At the moment, the mechanisms involved in particle-induced tumor formation are not clarified. However, it is suggested that inflammation, in conjunction with the production of reactive oxygen species (ROS) and an enhanc...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Nehls P,Seiler F,Rehn B,Greferath R,Bruch J

    更新日期:1997-09-01 00:00:00

  • Toward the effective surveillance of hypospadias.

    abstract::Concern about apparent increases in the prevalence of hypospadias--a congenital male reproductive-tract abnormality--in the 1960s to 1980s and the possible connection to increasing exposures to endocrine-disrupting chemicals have underlined the importance of effective surveillance of hypospadias prevalence in the popu...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Dolk H,Vrijheid M,Scott JE,Addor MC,Botting B,de Vigan C,de Walle H,Garne E,Loane M,Pierini A,Garcia-Minaur S,Physick N,Tenconi R,Wiesel A,Calzolari E,Stone D

    更新日期:2004-03-01 00:00:00

  • Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina.

    abstract::The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to interindividual variations in As metabolism that affect retention and distribution of toxic metabolites. To elucidate the role of genetic factors in As metabolism, we studied how polymorphisms in six genes affected the ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Schläwicke Engström K,Broberg K,Concha G,Nermell B,Warholm M,Vahter M

    更新日期:2007-04-01 00:00:00

  • Statistical properties of a two-stage model of carcinogenesis.

    abstract::Some of the statistical properties of a simple two-stage model of carcinogenesis are explored. The implications of additive treatment effects versus independent treatment effects on the shape of the dose-response curve are considered. Response that is low-dose linear results in the cases where the mutation rates are a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Portier CJ

    更新日期:1987-12-01 00:00:00

  • Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years.

    abstract:BACKGROUND:Sex-specific associations have been reported between phthalates, bisphenol A (BPA), and child behavior. No data on large study populations are available for other phenols with possible endocrine-disrupting properties. OBJECTIVES:We aimed to study associations between prenatal exposure to phthalates and seve...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Philippat C,Nakiwala D,Calafat AM,Botton J,De Agostini M,Heude B,Slama R,EDEN Mother–Child Study Group.

    更新日期:2017-09-15 00:00:00

  • Exposure to heterocyclic amines.

    abstract::Many mutagenic heterocyclic amines (HAs) have been isolated from cooked foods and pyrolysates of amino acids and proteins, and the carcinogenicity of 10 of these HAs in rodents and of 1 in monkeys has been reported. Quantification of these carcinogenic HAs in various kinds of cooked foods indicated that the level of 2...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Wakabayashi K,Ushiyama H,Takahashi M,Nukaya H,Kim SB,Hirose M,Ochiai M,Sugimura T,Nagao M

    更新日期:1993-03-01 00:00:00

  • Utilization of DNA-protein cross-links as a biomarker of chromium exposure.

    abstract::Human exposure to carcinogenic Cr(VI) compounds is found among workers in a large number of professional groups, and it can also occur through environmental pollution. A significant number of toxic waste sites contain Cr as a major contaminant. In this paper we summarize our efforts to apply measurements of DNA-protei...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Zhitkovich A,Voitkun V,Kluz T,Costa M

    更新日期:1998-08-01 00:00:00

  • Contribution of lead from calcium supplements to blood lead.

    abstract::We conducted a case-control study to determine the contribution of lead to blood from consumption of calcium supplements approximating the recommended daily intakes over a 6-month period. Subjects were males and females ages 21 to 47 years (geometric mean 32 years) with a geometric mean blood lead concentration of 2.5...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Gulson BL,Mizon KJ,Palmer JM,Korsch MJ,Taylor AJ

    更新日期:2001-03-01 00:00:00

  • Status of marine biomedical research.

    abstract::A meeting on Marine Biomedical Research, sponsored by the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health and the Smithsonian Institution Museum of Natural History, was attended by approximately 125 scientists, directors and representatives from many of the country's marine b...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Bessey O

    更新日期:1976-02-01 00:00:00

  • Climate and dengue transmission: evidence and implications.

    abstract:BACKGROUND:Climate influences dengue ecology by affecting vector dynamics, agent development, and mosquito/human interactions. Although these relationships are known, the impact climate change will have on transmission is unclear. Climate-driven statistical and process-based models are being used to refine our knowledg...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Morin CW,Comrie AC,Ernst K

    更新日期:2013-11-01 00:00:00

  • The role of plants and plant/microbial systems in the reduction of exposure.

    abstract::The activities of plants and plant/microbial associations may offer a viable means of accomplishing the in situ remediation of contaminated soils. Two uses of plants for phytoremediation are reported here. In one set of studies, the ability of plants to foster degradative microorganisms was investigated. Results indic...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Shann JR

    更新日期:1995-06-01 00:00:00

  • Genetic risk assessment and specific-locus mutations in the ad-3 region of Neurospora crassa.

    abstract::Data from experiments on the induction of specific-locus mutations in model systems are used in genetic risk assessment to estimate potential adverse effects in the human population. In such assessments with radiation or chemical mutagens, the following information is required: a) spontaneous and induced forward-mutat...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: de Serres FJ

    更新日期:1994-01-01 00:00:00

  • Predictors and variability of repeat measurements of urinary phenols and parabens in a cohort of Shanghai women and men.

    abstract:BACKGROUND:Exposure to certain phenols is ubiquitous because of their use in many consumer and personal care products. However, predictors of exposure have not been well characterized in most populations. OBJECTIVES:We sought to identify predictors of exposure and to assess the reproducibility of phenol concentrations...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Engel LS,Buckley JP,Yang G,Liao LM,Satagopan J,Calafat AM,Matthews CE,Cai Q,Ji BT,Cai H,Engel SM,Wolff MS,Rothman N,Zheng W,Xiang YB,Shu XO,Gao YT,Chow WH

    更新日期:2014-07-01 00:00:00

  • Defining the role of pollutants in the disruption of reproduction in wildlife.

    abstract::Although chemical exposure has been associated with reduced reproduction in certain North American fish, reptiles, and mammals, definitive cause-and-effect data are lacking in many instances. Because the increasing use and global transport of industrial chemicals pose significant risk to successful reproduction, metho...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Hose JE,Guillette LJ

    更新日期:1995-05-01 00:00:00

  • Use of remotely sensed data to evaluate the relationship between living environment and blood pressure.

    abstract:BACKGROUND:Urbanization has been correlated with hypertension (HTN) in developing countries undergoing rapid economic and environmental transitions. OBJECTIVES:We examined the relationships among living environment (urban, suburban, and rural), day/night land surface temperatures (LST), and blood pressure in selected ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Estes MG Jr,Al-Hamdan MZ,Crosson W,Estes SM,Quattrochi D,Kent S,McClure LA

    更新日期:2009-12-01 00:00:00

  • Relationships among polycyclic aromatic hydrocarbon-DNA adducts, proximity to the World Trade Center, and effects on fetal growth.

    abstract::Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants released by the World Trade Center (WTC) fires and various urban combustion sources. Benzo[a]pyrene (BaP) is a representative member of the class of PAHs. PAH-DNA adducts, or BaP-DNA adducts as their proxy, provide a measure of chemical-specific genetic dama...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Perera FP,Tang D,Rauh V,Lester K,Tsai WY,Tu YH,Weiss L,Hoepner L,King J,Del Priore G,Lederman SA

    更新日期:2005-08-01 00:00:00

  • Type of disinfectant in drinking water and patterns of mortality in Massachusetts.

    abstract::Chlorination has been the major strategy for disinfection of drinking water in the United States. Concern about the potential health effects of the reaction by-products of chlorine has prompted use of alternative strategies. One such method is chloramination, a treatment process that does not appear to have carcinogen...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Zierler S,Danley RA,Feingold L

    更新日期:1986-11-01 00:00:00

  • Estimation of relative bioavailability of lead in soil and soil-like materials using young Swine.

    abstract::In this article we summarize the results of a series of studies that measured the relative bioavailability (RBA) of lead in a variety of soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice a day for 15 days. Blood samples were col...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Casteel SW,Weis CP,Henningsen GM,Brattin WJ

    更新日期:2006-08-01 00:00:00

  • Nutritional needs in environmental intoxication: vitamin E and air pollution, an example.

    abstract::Dietary vitamin E affects the susceptibility of mice and rats to ozone and nitrogen dioxide, suggesting a free radical mechanism of toxicity. Conventional peroxidation does not completely explain the effects of alterations of lung fatty acid composition on both nitrogen dioxide and ozone toxicity. A new scheme is prop...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Menzel DB

    更新日期:1979-04-01 00:00:00

  • Monitoring indoor exposure to organophosphate flame retardants: hand wipes and house dust.

    abstract:BACKGROUND:Organophosphate flame retardants (PFRs) are becoming popular replacements for the phased-out polybrominated diphenyl ether (PBDE) mixtures, and they are now commonly detected in indoor environments. However, little is known about human exposure to PFRs because they cannot be easily measured in blood or serum...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Hoffman K,Garantziotis S,Birnbaum LS,Stapleton HM

    更新日期:2015-02-01 00:00:00

  • Drinking water contaminants, gene polymorphisms, and fetal growth.

    abstract::There are still many uncertainties regarding the risk of adverse pregnancy outcomes associated with exposure to drinking water disinfection by-products. In Montréal, Québec, Canada, we carried out a hospital-based case-control study including 493 cases of intrauterine growth restriction defined as birth weight below t...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Infante-Rivard C

    更新日期:2004-08-01 00:00:00

  • Bacterial mutagenicity of pyrolysis tars produced from chloro-organic fuels.

    abstract::Droplets of toluene and three chlorinated organics, ortho-dichlorobenzene, 1,2-dichloroethane, and trichloroethylene, were pyrolyzed in pure nitrogen. The composition and bacterial mutagenicity of the product tars were measured. The presence of organic chlorine was found to affect both pyrolysis product tar compositio...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Mulholland JA,Sarofim AF,Longwell JP,Lafleur AL,Thilly WG

    更新日期:1994-01-01 00:00:00

  • Metabolism of orally administered cadmium-metallothionein in mice.

    abstract::The main source of cadmium in the diet is cereal or meat, especially in liver and kidney. Since the cadmium in both liver and kidney is bound to metallothionein, a heat-stable protein, the gastrointestinal absorption and metabolism of cadmium metallothionein (CdMt) was studied in detail. The selective renal cadmium de...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Cherian MG

    更新日期:1979-02-01 00:00:00

  • Blood mercury reporting in NHANES: identifying Asian, Pacific Islander, Native American, and multiracial groups.

    abstract:INTRODUCTION:Asians, Pacific Islanders, and Native Americans are a potentially high-risk group for dietary exposure to methylmercury through fish consumption. However, blood mercury levels in this group have not been identified in recent reports of the National Health and Nutrition Examination Survey (NHANES) for the y...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Hightower JM,O'Hare A,Hernandez GT

    更新日期:2006-02-01 00:00:00