State monitoring activities related to Pfiesteria-like organisms.

abstract：:Nationwide, 45 states issue health advisories for sport fish consumers. Chemical contaminants in some Great Lakes (GL) sport fish include compounds suspected of causing adverse reproductive and developmental effects. Although advisories to reduce consumption of contaminated fish, especially by women, have been issued ...

journal_title：Environmental health perspectives

authors： Tilden J,Hanrahan LP,Anderson H,Palit C,Olson J,Kenzie WM

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:The U.S. Environmental Protection Agency is working toward gaining a better understanding of the human health impacts of exposure to complex air pollutant mixtures and the key features that drive the toxicity of these mixtures, which can then be used for future scientific and risk assessments. DATA SOURCES:...

journal_title：Environmental health perspectives

authors： Johns DO,Stanek LW,Walker K,Benromdhane S,Hubbell B,Ross M,Devlin RB,Costa DL,Greenbaum DS

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Green spaces have been associated with both health benefits and risks in children; however, available evidence simultaneously investigating these conflicting influences, especially in association with different types of greenness, is scarce. OBJECTIVES:We aimed to simultaneously evaluate health benefits and...

journal_title：Environmental health perspectives

authors： Dadvand P,Villanueva CM,Font-Ribera L,Martinez D,Basagaña X,Belmonte J,Vrijheid M,Gražulevičienė R,Kogevinas M,Nieuwenhuijsen MJ

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exposure assessments among average fish consumers in the United States may underestimate exposures among U.S. subpopulations with high intakes of regionally specific fish. OBJECTIVES:We examined relationships among fish consumption, estimated mercury (Hg) intake, and measured Hg exposur...

journal_title：Environmental health perspectives

authors： Lincoln RA,Shine JP,Chesney EJ,Vorhees DJ,Grandjean P,Senn DB

更新日期：2011-02-01 00:00:00

abstract：:Epidemiological studies examining the association between exposure to tap water contaminants (such as chlorination by-products) and disease outcomes (such as cancer and adverse reproductive outcomes) have been limited by inaccurate exposure assessment. Failure to take into account the variation in beverage and tap wat...

journal_title：Environmental health perspectives

authors： Shimokura GH,Savitz DA,Symanski E

更新日期：1998-02-01 00:00:00

abstract：:Toxicologic diseases of man and animals, associated with molds growing on foods, have been recognized for centuries. Only in recent years, however, have these mycotoxicoses received the attention of many laboratories and skilled scientists around the world in a broad inter-disciplinary effort. This review covers the l...

journal_title：Environmental health perspectives

authors： Newberne PM

更新日期：1974-12-01 00:00:00

abstract：BACKGROUND:Air pollution exposure increases cardiovascular morbidity and mortality and is a major global public health concern. OBJECTIVES:We investigated the benefits of reducing personal exposure to urban air pollution in patients with coronary heart disease. METHODS:In an open randomized crossover trial, 98 patien...

journal_title：Environmental health perspectives

authors： Langrish JP,Li X,Wang S,Lee MM,Barnes GD,Miller MR,Cassee FR,Boon NA,Donaldson K,Li J,Li L,Mills NL,Newby DE,Jiang L

更新日期：2012-03-01 00:00:00

abstract：:A review of the present understanding of asthma leads to the following conclusions: an elevated IgE is the principal risk factor in the development of childhood asthma; secondary exposure to a wide range of environmental agents (including indoor bioallergens) accounts for the variations in prevalence; prevalence (defi...

journal_title：Environmental health perspectives

authors： Bates DV

更新日期：1995-09-01 00:00:00

abstract：:Chronic exposure to inorganic arsenic (iAs) has been associated with increased risk of various forms of cancer and of noncancerous diseases. Metabolic conversions of iAs that yield highly toxic and genotoxic methylarsonite (MAsIII) and dimethylarsinite (DMAsIII) may play a significant role in determining the extent an...

journal_title：Environmental health perspectives

authors： Valenzuela OL,Borja-Aburto VH,Garcia-Vargas GG,Cruz-Gonzalez MB,Garcia-Montalvo EA,Calderon-Aranda ES,Del Razo LM

更新日期：2005-03-01 00:00:00

abstract：:Scientists at Pacific Northwest National Laboratory in Richland, Washington, have developed a unique imaging system capable of focusing on a single living cell within an organism. This new technology will be used in what the multidisciplinary team has termed a "cellular observatory" to study the effect of environmenta...

journal_title：Environmental health perspectives

authors： Medlin J

更新日期：1999-11-01 00:00:00

abstract：:The relationship between blood lead concentration and blood pressure is examined in a survey of 7371 men aged 40 to 59 from 24 British towns. After allowance for relevant confounding variables, including town of residence and alcohol consumption, there exists a very weak but statistically significant positive associat...

journal_title：Environmental health perspectives

authors： Pocock SJ,Shaper AG,Ashby D,Delves HT,Clayton BE

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:Animal feeding practices in the United States have changed considerably over the past century. As large-scale, concentrated production methods have become the predominant model for animal husbandry, animal feeds have been modified to include ingredients ranging from rendered animals and animal waste to antibi...

journal_title：Environmental health perspectives

authors： Sapkota AR,Lefferts LY,McKenzie S,Walker P

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Diethylstilbestrol (DES) is a synthetic estrogen associated with adverse effects on reproductive organs. DES-induced toxicity of the mouse seminal vesicle (SV) is mediated by estrogen receptor α (ERα), which alters expression of seminal vesicle secretory protein IV (Svs4) and lactoferrin (Ltf) genes. OBJECT...

journal_title：Environmental health perspectives

authors： Li Y,Hamilton KJ,Lai AY,Burns KA,Li L,Wade PA,Korach KS

更新日期：2014-03-01 00:00:00

abstract：:Present available information regarding ovarian tumors in hens is incomplete in most aspects, and this lack of knowledge hampers use of hens as models for study of ovarian cancer. A study of 466 hens ranging from 2 to 7 years of age and covering a period of more than 3 years has provided much needed information relati...

journal_title：Environmental health perspectives

authors： Fredrickson TN

更新日期：1987-08-01 00:00:00

abstract：:Carcinogenic nickel compounds are usually found to be weak mutagens; therefore these compounds may not exert their carcinogenic activity through conventional genotoxic mechanisms. On the other hand, the activities of many nickel compounds have not been adequately investigated. We evaluated the genotoxic activities of ...

journal_title：Environmental health perspectives

authors： Au WW,Heo MY,Chiewchanwit T

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Enteric illness arising from contaminated water and food is a major health concern worldwide, and tracking the incidences and severity of outbreaks is still a challenging task. Most developed and developing countries have administrative databases for medical visits and services maintained by the government a...

journal_title：Environmental health perspectives

authors： Peace T,Mazumder A

更新日期：2007-01-01 00:00:00

abstract：:The progression of the cell cycle is controlled by the action of both positive and negative growth regulators. The key players in this activity include a family of cyclins and cyclin-dependent kinases, which are themselves regulated by other kinases and phosphatases. Maintenance of balanced cell cycle controls may be ...

journal_title：Environmental health perspectives

authors： Afshari CA,Barrett JC

更新日期：1993-12-01 00:00:00

abstract：:The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was i...

journal_title：Environmental health perspectives

authors： Mazzullo M,Bartoli S,Bonora B,Colacci A,Grilli S,Lattanzi G,Niero A,Turina MP,Parodi S

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exposure has been linked to an increased risk of coronary heart disease (CHD). Paraoxonase 1 (PON1), an enzyme located in the high-density-lipoprotein (HDL) fraction of blood lipids, may protect against CHD by metabolizing toxic oxidized lipids associated with low-density liproprotein an...

journal_title：Environmental health perspectives

authors： Ayotte P,Carrier A,Ouellet N,Boiteau V,Abdous B,Sidi EA,Château-Degat ML,Dewailly É

更新日期：2011-08-01 00:00:00

abstract：:Uterine leiomyomas (fibroids, myomas) are the most common tumors occurring in the genital tract of women over 30 years of age. These benign uterine smooth-muscle tumors are estimated to be clinically significant in at least 25% of the American female population during their reproductive years. Furthermore, when thorou...

journal_title：Environmental health perspectives

authors： Newbold RR,DiAugustine RP,Risinger JI,Everitt JI,Walmer DK,Parrott EC,Dixon D

更新日期：2000-10-01 00:00:00

abstract：:Most of the composites and sealants used in dentistry are based on bisphenol A diglycidylether methacrylate (Bis-GMA). Reports revealed that in situ polymerization is not complete and that free monomers can be detected by different analytic methods. Concerns about the estrogenicity of bisphenol A (BPA) and other aroma...

journal_title：Environmental health perspectives

authors： Pulgar R,Olea-Serrano MF,Novillo-Fertrell A,Rivas A,Pazos P,Pedraza V,Navajas JM,Olea N

更新日期：2000-01-01 00:00:00

abstract：:Chlorination has been the major strategy for disinfection of drinking water in the United States. Concern about the potential health effects of the reaction by-products of chlorine has prompted use of alternative strategies. One such method is chloramination, a treatment process that does not appear to have carcinogen...

journal_title：Environmental health perspectives

authors： Zierler S,Danley RA,Feingold L

更新日期：1986-11-01 00:00:00

abstract：:To evaluate the effectiveness of mass screening for uterine cancer in Japan, we compared the changes in the age-adjusted rates of potential years of life lost (PYLL) due to uterine cancer between 1969 and 1972 to 1973 through 1977 between the high coverage-rate (intensively screened) areas and the comparable control a...

journal_title：Environmental health perspectives

authors： Kuroishi T,Hirose K,Tominaga S

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies of postnatal PCB exposure and behavior have not reported consistent evidence of adverse associations, possibly because of challenges in exposure estimation. We previously developed a pharmacokinetic model to improve estimation of children's PCB exposure. OBJECTIVES:We aimed to assess w...

journal_title：Environmental health perspectives

authors： Verner MA,Hart JE,Sagiv SK,Bellinger DC,Altshul LM,Korrick SA

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent. OBJECTIVES:We assessed long-term exposure to trihalomethanes (THMs), the most prevalent group of chlorination by-products, to evaluate the association with colorectal cancer. ME...

journal_title：Environmental health perspectives

authors： Villanueva CM,Gracia-Lavedan E,Bosetti C,Righi E,Molina AJ,Martín V,Boldo E,Aragonés N,Perez-Gomez B,Pollan M,Acebo IG,Altzibar JM,Zabala AJ,Ardanaz E,Peiró R,Tardón A,Chirlaque MD,Tavani A,Polesel J,Serraino D,Pi

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In an effort to decrease the rates of smoking conventional tobacco cigarettes, electronic cigarettes (e-cigarettes) have been proposed as an effective smoking cessation tool. However, little is known about their toxicological impacts. This is concerning given that e-cigarette use is perceived as less harmful...

journal_title：Environmental health perspectives

authors： Church JS,Chace-Donahue F,Blum JL,Ratner JR,Zelikoff JT,Schwartzer JJ

更新日期：2020-04-01 00:00:00

abstract：:This study assessed whether exposure of male rats to two estrogenic, environmental chemicals, 4-octylphenol (OP) and butyl benzyl phthalate (BBP) during gestation or during the first 21 days of postnatal life, affected testicular size or spermatogenesis in adulthood (90-95 days of age). Chemicals were administered via...

journal_title：Environmental health perspectives

authors： Sharpe RM,Fisher JS,Millar MM,Jobling S,Sumpter JP

更新日期：1995-12-01 00:00:00

abstract：:In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. In recent years their actual advantages and limitations have been better defined. The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions...

journal_title：Environmental health perspectives

authors： Guillouzo A

更新日期：1998-04-01 00:00:00

abstract：:Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evo...

journal_title：Environmental health perspectives

authors： Braun JM,Gennings C,Hauser R,Webster TF

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Controversy remains regarding the relationship between ambient ozone and mortality worldwide. In mainland China, the largest developing country, there has been no prior study investigating the acute effect of O3 on death risk. Given the changes in types of air pollution from conventional coal combustion to t...

journal_title：Environmental health perspectives

authors： Zhang Y,Huang W,London SJ,Song G,Chen G,Jiang L,Zhao N,Chen B,Kan H

更新日期：2006-08-01 00:00:00