Sphaeroane and neodolabellane diterpenes from the red alga Sphaerococcus coronopifolius.

Abstract:

:Investigation of minor metabolites in the extracts of the red alga Sphaerococcus coronopifolius collected from the rocky coasts of Corfu Island in the Ionian Sea yielded two new diterpene alcohols, sphaerollanes I, and II (1, 2) featuring neodolabellane skeletons, and the new sphaeroane diterpene alcohol 16-hydroxy-9S*-acetoxy-8-epi-isosphaerodiene-2 (3), along with two previously reported metabolites 4, 5. The structures of the new natural products, as well as their relative stereochemistry, were elucidated on the basis of extensive spectral analysis, including 2D-NMR experiments.

journal_name

Mar Drugs

journal_title

Marine drugs

authors

Smyrniotopoulos V,Vagias C,Roussis V

doi

10.3390/md7020184

subject

Has Abstract

pub_date

2009-05-19 00:00:00

pages

184-95

issue

2

issn

1660-3397

journal_volume

7

pub_type

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