Targets and effects of yessotoxin, okadaic acid and palytoxin: a differential review.

Abstract:

:In this review, we focus on processes, organs and systems targeted by the marine toxins yessotoxin (YTX), okadaic acid (OA) and palytoxin (PTX). The effects of YTX and their basis are analyzed from data collected in the mollusc Mytilus galloprovincialis, the annelid Enchytraeus crypticus, Swiss CD1 mice and invertebrate and vertebrate cell cultures. OA and PTX, two toxins with a better established mode of action, are analyzed with regard to their effects on development. The amphibian Xenopus laevis is used as a model, and the Frog Embryo Teratogenesis Assay-Xenopus (FETAX) as the experimental protocol.

journal_name

Mar Drugs

journal_title

Marine drugs

authors

Franchini A,Malagoli D,Ottaviani E

doi

10.3390/md8030658

subject

Has Abstract

pub_date

2010-03-16 00:00:00

pages

658-77

issue

3

issn

1660-3397

journal_volume

8

pub_type

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