Abstract：
:The antiproliferative activity of 52 volatile compounds released from bacteria was investigated in agar diffusion assays against medically important microorganisms and mouse fibroblasts. Furthermore, the activity of these compounds to interfere with the quorum-sensing-systems was tested with two different reporter strains. While some of the compounds specific to certain bacteria showed some activity in the antiproliferative assay, the compounds common to many bacteria were mostly inactive. In contrast, some of these compounds were active in the quorum-sensing-tests. γ-Lactones showed a broad reactivity, while pyrazines seem to have only low intrinsic activity. A general discussion on the ecological importance of these findings is given.
journal_name
Mar Drugsjournal_title
Marine drugsauthors
Schulz S,Dickschat JS,Kunze B,Wagner-Dobler I,Diestel R,Sasse Fdoi
10.3390/md8122976subject
Has Abstractpub_date
2010-12-22 00:00:00pages
2976-87issue
12issn
1660-3397journal_volume
8pub_type
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