Growth signaling at the nexus of stem cell life and death.

Abstract:

:Stress can activate tumor-suppressive mechanisms, causing the loss of adult stem cell function with age. In this issue of Cell Stem Cell and in Nature, Castilho et al. (2009) and Harrison et al. (2009) highlight the importance of mTOR signaling in stem cell exhaustion and mammalian aging, respectively.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Wood KC,Sabatini DM

doi

10.1016/j.stem.2009.08.008

subject

Has Abstract

pub_date

2009-09-04 00:00:00

pages

232-4

issue

3

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(09)00393-2

journal_volume

5

pub_type

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