Abstract:
:Seeing begins in the photoreceptors, where light is absorbed and signaled to the nervous system. Throughout the animal kingdom, photoreceptors are diverse in design and purpose. Nonetheless, phototransduction-the mechanism by which absorbed photons are converted into an electrical response-is highly conserved and based almost exclusively on a single class of photoproteins, the opsins. In this Review, we survey the G protein-coupled signaling cascades downstream from opsins in photoreceptors across vertebrate and invertebrate species, noting their similarities as well as differences.
journal_name
Celljournal_title
Cellauthors
Yau KW,Hardie RCdoi
10.1016/j.cell.2009.09.029subject
Has Abstractpub_date
2009-10-16 00:00:00pages
246-64issue
2eissn
0092-8674issn
1097-4172pii
S0092-8674(09)01244-6journal_volume
139pub_type
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