当前位置： SCI文献检索 > European Journal of Internal Medicine期刊下所有文献 > Erectile dysfunction and adherence to antihypertensive therapy: Focus on β-blockers.

Erectile dysfunction and adherence to antihypertensive therapy: Focus on β-blockers.

Abstract：

:The management of arterial hypertension is very challenging in everyday clinical practice. Blood pressure control rates remain disappointingly low, despite intense efforts. Poor adherence to antihypertensive treatment is among the main causes of inadequate blood pressure control. Among the various parameters leading to poor adherence, medication adverse events seem to be the prevailing cause of treatment discontinuation. Β-blockers are a class of drugs commonly used in the management of hypertension. However, β-blockers use has been associated with various adverse events, among which, erectile dysfunction is a prevalent one. Accumulating evidence supports the detrimental role of β-blockers on erectile function. Older studies have shown contradictory findings, which however may be attributed to methodological errors related with the assessment of erectile function. More recent studies, however, unveiled the negative impact of this drug category on erectile function. Nevertheless, β-blockers represent a class of drugs with substantial within class heterogeneity. Nebivolol presents a unique mode of action through enhanced nitric oxide bioavailability that may be associated with benefits on erectile function. Indeed, studies of nebivolol have shown improvement in erectile function, suggesting that nebivolol represents the only exception in this class of drugs in terms of erectile function.

journal_name

Eur J Intern Med

journal_title

European journal of internal medicine

authors

Manolis A,Doumas M,Ferri C,Mancia G

doi

10.1016/j.ejim.2020.07.009

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

1-6

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(20)30292-2

journal_volume

81

pub_type

杂志文章,评审

相关文献

European Journal of Internal Medicine文献大全
  • Changes in lipid and carbohydrate metabolism under mTOR- and calcineurin-based immunosuppressive regimen in adult patients after liver transplantation.

    abstract：BACKGROUND:Cardiovascular disease is a leading cause of long-term mortality after liver transplantation (LT). Life long immunosuppression harbors the risk of metabolic alterations. We aimed to analyze the impact of calcineurin (CNI)-only containing regimen (group A) compared to mTOR-containing regimen (group B) on lipi...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2015.12.022

    authors： Zimmermann A,Zobeley C,Weber MM,Lang H,Galle PR,Zimmermann T

    更新日期：2016-04-01 00:00:00

  • Hepatitis B remains a major health priority in Western Balkans: results of a 4-year prospective Greek-Albanian collaborative study.

    abstract：OBJECTIVE OF THE STUDY:To report on the results of two projects on chronic hepatitis B in Western Balkans lead by Ioannina, Northwest Greece and Tirana, Albania. METHODS:In two prospective projects, HEPAGA I and HEPAGA II which lasted 4 years. In HEPAGA I, serum samples from 410 Albanians were tested for HBV. In HEPAG...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2009.07.016

    authors： Katsanos KH,Christodoulou DK,Zervou E,Babameto A,Kraja B,Hyphantis H,Karetsos V,Tsonis G,Basho J,Resuli BF,Tsianos EV

    更新日期：2009-11-01 00:00:00

  • Efficacy and safety of Monascus purpureus Went rice in children and young adults with secondary hyperlipidemia: a preliminary report.

    abstract：BACKGROUNDS/AIMS:Nephrotic dyslipidemia is a risk factor for development of systemic atherosclerosis; also it may aggravate glomerulosclerosis and enhance progression of glomerular disease. We aimed to assess the efficacy and safety of Monascus purpureus Went rice vs. fluvastatin therapy in the management of nephrotic ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ejim.2008.08.012

    authors： Gheith O,Sheashaa H,Abdelsalam M,Shoeir Z,Sobh M

    更新日期：2009-05-01 00:00:00

  • Arterial erectile dysfunction: different severities of endothelial apoptosis between diabetic patients "responders" and "non responders" to sildenafil.

    abstract：BACKGROUND:The low pharmacological response to phosphodiesterase type 5 inhibitors represents an expression of higher endothelial damage in certain categories of patients with erectile dysfunction and high cardiovascular risk. The present study evaluated this objective in type 2 diabetic patients with erectile dysfunct...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2013.01.001

    authors： Condorelli RA,Calogero AE,Favilla V,Morgia G,Johnson EO,Castiglione R,Salemi M,Mongioí L,Nicoletti C,Duca Y,Di Mauro M,Vicari E,La Vignera S

    更新日期：2013-04-01 00:00:00

  • Historical study of acute hepatitis B in subjects with or without hepatitis C infection.

    abstract：BACKGROUND:The epidemiological pattern of hepatitis B virus infection in Italy has greatly changed over the past decades. The aim of the study was to evaluate during time the epidemiological features of acute hepatitis B cases referred to an Infectious Disease Unit in North-East of Italy between 1978 and 1995. PATIENT...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2012.03.007

    authors： Stroffolini T,Rapicetta M,Lombardo F,Chionne P,Madonna E,Candido A,Taffon S,Rinaldi R,Ermg E,Bortolotti F

    更新日期：2012-09-01 00:00:00

  • External validation of the CACE-HF risk score for mortality in patients with heart failure.

    abstract：AIMS:To validate externally the CACE-HF clinical prediction rule, which predicts 1-year mortality in patients with heart failure (HF). METHODS:We performed an external validation of the CACE-HF risk score in patients included in the RICA heart failure registry who had completed 1 year of follow-up, comparing the chara...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ejim.2019.05.010

    authors： Quirós-López R,Manzano-Espinosa L,Bilbao A,Montero Pérez-Barquero M,Cepeda-Rodrigo JM,Escobar-Martínez A

    更新日期：2019-08-01 00:00:00

  • Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS).

    abstract：:Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2015.02.020

    authors： Onder G,Palmer K,Navickas R,Jurevičienė E,Mammarella F,Strandzheva M,Mannucci P,Pecorelli S,Marengoni A,Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS).

    更新日期：2015-04-01 00:00:00

  • Online combination algorithm for non-invasive assessment of chronic hepatitis B related liver fibrosis and cirrhosis in resource-limited settings.

    abstract：OBJECTIVE:The use of commercially available noninvasive markers for chronic hepatitis B (CHB) related fibrosis is not widely available in developing countries so clinicians in those countries frequently use free alternatives. We aimed to create an optimized algorithm for selection of patients with the highest probabili...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2015.07.005

    authors： Salkic NN,Cickusic E,Jovanovic P,Denjagic MB,Iljazovic-Topcic S,Bevanda M,Ahmetagic S

    更新日期：2015-10-01 00:00:00

  • Early repolarization syndrome and Brugada syndrome: is there any linkage?

    abstract：:Early repolarization syndrome (ERS) is characterized by the presence, in most cases in mid-to-lateral precordial leads, of a J wave on the downsloping portion of the QRS complex, followed by an elevation of the ST-segment with upward concavity. ERS is considered a benign electrocardiographic pattern of ventricular rep...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2007.06.013

    authors： Di Grande A,Tabita V,Lizzio MM,Giuffrida C,Bellanuova I,Lisi M,Le Moli C,Amico S

    更新日期：2008-06-01 00:00:00

  • The 2020 International Society of Hypertension global hypertension practice guidelines - key messages and clinical considerations.

    abstract：:The International Society of Hypertension (ISH) has recently developed practice guidelines for the management of hypertension in adults aged ≥18 years. Conceptually, the 2020 ISH Guidelines are closer to the 2018 ESC/ESH Guidelines rather than to the 2017 ACC/AHA Guidelines. The ISH Guidelines have two distinctive fea...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2020.09.001

    authors： Verdecchia P,Reboldi G,Angeli F

    更新日期：2020-12-01 00:00:00

  • Long-term outcome of patients with macroprolactinomas initially treated with dopamine agonists.

    abstract：OBJECTIVE:Dopamine agonists are the first line therapy for the treatment of prolactinomas. The aim of this study was to assess the outcome of macroprolactinomas during long-term follow-up after initial treatment with dopamine agonists. DESIGN:Retrospective follow-up study. PATIENTS:We included 72 consecutive patients...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2008.11.012

    authors： Kars M,Pereira AM,Smit JW,Romijn JA

    更新日期：2009-07-01 00:00:00

  • Autoimmune manifestations in acquired idiopathic splenic atrophy: A puzzling association.

    abstract：:Splenic atrophy is an uncommon diagnosis associated with celiac sprue or other well-characterized connective tissue diseases, drepanocytosis, or amyloidosis. We report two patients with splenic atrophy revealed by thrombocytosis. Both patients had anti-nuclear antibodies. Patient 1 also had a grade III Chisholm lympho...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2006.07.008

    authors： Coppo P,Saadoun D,Varet B

    更新日期：2006-12-01 00:00:00

  • A comparative analysis of novel cardiovascular biomarkers in patients with chronic heart failure.

    abstract：BACKGROUND:Heart failure (HF) with reduced ejection fraction remains a major therapeutic challenge. The aim of this study was to investigate the role of novel cardiovascular biomarkers, i.e. soluble suppression of tumorigenicity (sST2), growth-differentiation factor-15 (GDF-15), soluble urokinase plasminogen activator ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2017.05.027

    authors： Lichtenauer M,Jirak P,Wernly B,Paar V,Rohm I,Jung C,Schernthaner C,Kraus J,Motloch LJ,Yilmaz A,Hoppe UC,Christian Schulze P,Kretzschmar D,Pistulli R

    更新日期：2017-10-01 00:00:00

  • β-Thalassemia heterozygote state detrimentally affects health expectation.

    abstract：BACKGROUND:Thalassemia minor (Tm) individuals, are generally considered healthy. However, the prognosis of Tm individuals has not been extensively studied. The aim of this study was to evaluate the prognosis of Tm versus controls without β-thalassemia carrier state. METHODS:A total of 26,006 individuals seeking thalas...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2018.06.009

    authors： Graffeo L,Vitrano A,Scondotto S,Dardanoni G,Pollina Addario WS,Giambona A,Sacco M,Di Maggio R,Renda D,Taormina F,Triveri A,Attanasio M,Gluud C,Maggio A

    更新日期：2018-08-01 00:00:00

  • Nocardiosis: a 15-year experience in a tertiary medical center in Israel.

    abstract：OBJECTIVES:The objective of this study is to characterize the common risk factors, clinical presentation, imaging findings, treatment and outcome of nocardial infection. DESIGN AND SETTINGS:A retrospective cohort study. We reviewed the charts of all patients with nocardiosis in the Chaim Sheba Medical Center, a tertia...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2013.05.004

    authors： Rosman Y,Grossman E,Keller N,Thaler M,Eviatar T,Hoffman C,Apter S

    更新日期：2013-09-01 00:00:00

  • Extrapulmonary tuberculosis in the northeastern suburbs of Paris: 141 cases.

    abstract：:Background: Big cities were particularly affected by tuberculosis in the 1990s. Methods: We studied 141 cases of extrapulmonary tuberculosis in patients not infected by HIV in the northeastern suburbs of Paris. Results: A total of 84 men and 57 women were included in the study. Their average age at diagnosis was 42.2 ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/s0953-6205(00)00076-5

    authors： Fain O,Lortholary O,Lascaux V V,Amoura I I,Babinet P,Beaudreuil J,Boudon P,Cruaud P,Desrues J,Djouab M,Glowinski J,Lhote F,Kettaneh A,Malbec D,Mathieu E,Taleb C,Guillevin L,Thomas M

    更新日期：2000-06-01 00:00:00

  • Influence of BMI and geographical region on prescription of oral anticoagulants in newly diagnosed atrial fibrillation: The GLORIA-AF Registry Program.

    abstract：OBJECTIVE:To investigate the association between body mass index (BMI) and oral anticoagulant (OAC) prescription in atrial fibrillation (AF). METHODS:Patients with newly diagnosed non-valvular AF (<3 months) with ≥1 stroke risk factors enrolled in the Global Registry on Long-Term Oral Antithrombotic Treatment in Patie...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2020.04.032

    authors： Boriani G,Huisman MV,Teutsch C,Marler S,França LR,Lu S,Lip GYH,GLORIA-AF Investigators.

    更新日期：2020-10-01 00:00:00

  • Portopulmonary hypertension: from diagnosis to treatment.

    abstract：:Portopulmonary hypertension is a form of pulmonary arterial hypertension that has gained interest in recent years with the development of liver transplantation techniques and new pulmonary vasodilator therapies. Portopulmonary hypertension is defined as pulmonary artery hypertension associated with portal hypertension...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2011.02.018

    authors： Giusca S,Jinga M,Jurcut C,Jurcut R,Serban M,Ginghina C

    更新日期：2011-10-01 00:00:00

  • Why optional inferior vena cava filters are not always retrieved? A real world 19 years experience in a Swiss tertiary care university hospital.

    abstract：BACKGROUND:inferior vena cava filters (IVCF) are widely used to prevent thromboembolic events in patients not suitable for anticoagulation (AC). Although new generations of filters are optional and therefore retrievable, most of them become permanent. Aim of our study was to evaluate real life IVCF management in a tert...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2020.01.025

    authors： Buso G,Alatri A,Calanca L,Fresa M,Qanadli SD,Pesavento R,Mazzolai L

    更新日期：2020-06-01 00:00:00

  • Plasma homocysteine, angiographically proven coronary artery disease, and wine consumption.

    abstract：:BACKGROUND: Plasma total homocysteine (p-tHcy) is considered to be an independent risk factor for atherosclerotic vascular disease. This cross-sectional study was undertaken to examine p-tHcy levels and their relationship to coronary artery disease (CAD) and alcohol intake. METHODS: We consecutively studied 291 patien...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/s0953-6205(03)00069-4

    authors： Toft E,Ellegaard Hansen V,Hagstrup Christensen J,Berg Schmidt E,Aarup Skou H,Fog L,Ekelund S,Dyerberg J

    更新日期：2003-07-01 00:00:00

  • Current methods to diagnose the unresponsive and complicated forms of coeliac disease.

    abstract：:Coeliac disease is a common disorder. Due to the protean manifestations of the disease and the often mild but indolent course, the diagnosis is often missed. The method to diagnose this in principle reversible disease after the introduction of a gluten-free diet has attracted the attention of several scientific discip...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2010.01.015

    authors： Hadithi M,Peña AS

    更新日期：2010-08-01 00:00:00

  • Coronary stent bacterial infection with multiple organ septic emboli.

    abstract：:We describe an 80-year-old patient who developed Staphylococcus aureus septicemia several days after the implantation of a double stent in the proximal and mid-left anterior descending artery. The infection was complicated by multiple abscesses in the lungs and liver, as well as by bilateral bacterial endophthalmitis ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2004.10.010

    authors： Hoffman M,Baruch R,Kaplan E,Mittelman M,Aviram G,Siegman-Igra Y

    更新日期：2005-04-01 00:00:00

  • The effect of fatty pancreas on serum glucose parameters in patients with nonalcoholic steatohepatitis.

    abstract：OBJECTIVE:Fatty pancreas (FP) is related to obesity, and may have some clinical implications on glucose metabolism. The frequency and importance of FP in patients with nonalcoholic steatohepatitis (NASH) are not clear. This study aimed to investigate: the frequency of FP in patients with NASH, and its effects on serum ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2014.11.007

    authors： Uygun A,Kadayifci A,Demirci H,Saglam M,Sakin YS,Ozturk K,Polat Z,Karslioglu Y,Bolu E

    更新日期：2015-01-01 00:00:00

  • ANCA associated vasculitis.

    abstract：:Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitan...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2020.01.011

    authors： Salvador F

    更新日期：2020-04-01 00:00:00

  • Clinical characteristics and prognostic significance of serum albumin changes in an internal medicine ward.

    abstract：BACKGROUND:The prognostic significance of hypoalbuminemia and the dynamic changes in serum albumin during hospitalization in internal medicine wards has not been sufficiently investigated. METHODS:Demographic, clinical and laboratory data were collected from 276 patients admitted to our internal medicine ward for a va...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2013.08.004

    authors： Barchel D,Almoznino-Sarafian D,Shteinshnaider M,Tzur I,Cohen N,Gorelik O

    更新日期：2013-12-01 00:00:00

  • Impact of pre-hospital renal function on the detection of acute kidney injury in acute decompensated heart failure.

    abstract：BACKGROUND:Acute kidney injury (AKI) is a serious complication in patients hospitalized for decompensated heart failure (HF). Currently, AKI definitions consider creatinine levels at admission as reference of baseline renal function (RF). However, renal impairment may already be present at admission. We aimed to study ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2020.02.028

    authors： Sanchez-Serna J,Hernandez-Vicente A,Garrido-Bravo IP,Pastor-Perez F,Noguera-Velasco JA,Casas-Pina T,Rodriguez-Serrano AI,Núñez J,Pascual-Figal D

    更新日期：2020-07-01 00:00:00

  • Thromboprophylaxis in the oldest old with atrial fibrillation: between Scylla and Charybdis.

    abstract：:Within a few decades half of the patients with non-valvular atrial fibrillation (AF) will be older than 80 years. These patients are at particularly high risk of thromboembolism (Scylla) but also of the hemorrhagic complications of thromboprophylaxis (Charybdis). A frequent compromise is to use as antithrombotic agent...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2013.02.001

    authors： Mannucci PM

    更新日期：2013-06-01 00:00:00

  • Prediction clinical profile to distinguish between systolic and diastolic heart failure in hospitalized patients.

    abstract：BACKGROUND:In recent decades, the growing incidence of patients with heart failure who have preserved systolic function, underlines the need to differentiate between heart failure due to diastolic dysfunction and that due to systolic dysfunction. OBJECTIVE:To develop a prediction profile of clinical parameters that en...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2008.09.001

    authors： Maestre A,Gil V,Gallego J,García M,García de Burgos F,Martín-Hidalgo A

    更新日期：2009-05-01 00:00:00

  • Reported parental age of death in type 2 diabetic patients with and without established diabetic nephropathy.

    abstract：BACKGROUND:Diabetic patients with renal disease have increased mortality, largely from cardiovascular disease. This could be related to insulin resistance or to other inherited factors. The aim of the present study was to investigate whether there is evidence of the familial aggregation of increased mortality, even in ...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章

    doi：10.1016/j.ejim.2005.07.005

    authors： Fava S,Hattersley AT

    更新日期：2005-11-01 00:00:00

  • Efficacy and safety of incretin-based therapies in patients with type 2 diabetes mellitus.

    abstract：:This article aims to provide an overview of efficacy and safety data on glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors in the treatment of type 2 diabetes mellitus. Our goal is to differentiate the clinical profiles of GLP-1 receptor agonists and DPP-4 inhibitors, as we...

    journal_title：European journal of internal medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.ejim.2009.05.011

    authors： Gilbert MP,Pratley RE

    更新日期：2009-07-01 00:00:00