Abstract:
:Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitants. It is the result of the interaction of infectious, genetic and environmental factors and manifest itself with varied and unspecific symptoms, often reaching the general state, respiratory and renal systems. The combination of clinical, laboratory, imaging and fundamentally histological changes allows the diagnosis and classification of the extent / severity of the disease necessary for the decision of the therapeutics to be taken. Glucocorticoids are generally used; with methotrexate being considered when localized disease and cyclophosphamide, rituximab or azathioprine when generalized disease. A systematized approach can increase survival rates from 12% to 70% over a 5-year span.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Salvador Fdoi
10.1016/j.ejim.2020.01.011subject
Has Abstractpub_date
2020-04-01 00:00:00pages
18-28eissn
0953-6205issn
1879-0828pii
S0953-6205(20)30011-Xjournal_volume
74pub_type
杂志文章,评审abstract::Pattern recognition of the long-term disease course before, during, and after pregnancy can provide us with data about the influence of pregnancy on IBD, and vice versa. Determinants that predict an indolent versus an aggressive disease course are currently being sought. Our intention is to analyze the disease course ...
journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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pub_type: 杂志文章,评审
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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journal_title:European journal of internal medicine
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