Abstract：
:Splenic atrophy is an uncommon diagnosis associated with celiac sprue or other well-characterized connective tissue diseases, drepanocytosis, or amyloidosis. We report two patients with splenic atrophy revealed by thrombocytosis. Both patients had anti-nuclear antibodies. Patient 1 also had a grade III Chisholm lymphocytic sialadenitis with a rheumatoid factor, anti-extractable nuclear antibodies, and a polyclonal hypergammaglobulinemia consistent with the diagnosis of Sjögren's syndrome. Patient 2 displayed a previous history of idiopathic pericarditis. An anti-pneumococcal vaccination was given to both patients and neither experienced infectious complications. Splenic atrophy should be suspected in patients with thrombocytosis of unexplained origin and a blood smear consistent with asplenia. Such patients must be checked for clinical and biological symptoms of autoimmune disorders.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Coppo P,Saadoun D,Varet Bdoi
10.1016/j.ejim.2006.07.008subject
Has Abstractpub_date
2006-12-01 00:00:00pages
580-2issue
8eissn
0953-6205issn
1879-0828pii
S0953-6205(06)00192-0journal_volume
17pub_type
杂志文章abstract：:Most patients above 60 years with acute myeloid leukemia (AML) will die from their disease. Nevertheless, the treatment concepts in elderly patients with myelodysplastic syndromes (MDS) and AML are rapidly evolving. A number of recent reports have identified better survival rates with intensive induction chemotherapy ...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2018.05.026
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Cardiovascular disease is a leading cause of long-term mortality after liver transplantation (LT). Life long immunosuppression harbors the risk of metabolic alterations. We aimed to analyze the impact of calcineurin (CNI)-only containing regimen (group A) compared to mTOR-containing regimen (group B) on lipi...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.12.022
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To investigate the association between body mass index (BMI) and oral anticoagulant (OAC) prescription in atrial fibrillation (AF). METHODS:Patients with newly diagnosed non-valvular AF (<3 months) with ≥1 stroke risk factors enrolled in the Global Registry on Long-Term Oral Antithrombotic Treatment in Patie...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.04.032
更新日期：2020-10-01 00:00:00
abstract：:We report a case of hypocomplementemic urticarial vasculitis heralding a relapsing polychondritis in a 63-year-old woman. The patient, who had suffered in the past from polymyalgia rheumatica, suddenly experienced a generalized urticarial eruption with a dramatic decrease in C4 complement fraction and the presence of ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2004.10.022
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:In a previous study involving 18 hypertensive patients with type 2 diabetes mellitus, we found that replacement of valsartan and candesartan by telmisartan significantly improved insulin sensitivity and significantly increased serum adiponectin levels in the patients. We investigated the effects of 3 angioten...
journal_title：European journal of internal medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ejim.2010.01.014
更新日期：2010-06-01 00:00:00
abstract：:Stroke is a leading cause of death worldwide and the first cause of disability in the Western world. Over the last 20 years, antiplatelet agents have reduced overall stroke rates in primary and secondary prevention in men. However, this has not been the case for women. In this narrative review, the most widely used an...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2012.04.010
更新日期：2012-10-01 00:00:00
abstract：:The names of many drugs look or sound like those of other drugs, which leads to confusion and potentially harmful medication errors. We report a nearly fatal permutation between two drugs including a vitamin K antagonist that resulted in a 68-year-old man being admitted to the emergency department with severe, spontan...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2007.03.018
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:In Greece, there are few data on the epidemiological characteristics of HBV. Our aim was to study the epidemiological patterns of HBV in Central Greece and identify the possible differences in HBV prevalence (clusters) among areas inside this region using data from the hepatitis registry. METHODS:The study ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.04.023
更新日期：2009-01-01 00:00:00
abstract：:The belief that hospital stays may constitute per se a risk for patients is not widespread among patients and health care professionals. In the balance between advantages and disadvantages of admission, we rarely take into account the impact of the hospital stay itself on the well-being of the patient. In a society th...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.06.003
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Aspiration pneumonia (AP) is an infectious process causing high rates of mortality. The purpose of this study was: 1, to describe the incidence from 2003 to 2013 of AP hospitalizations; 2, to assess time trends in hospital outcomes variables, and; 3, to identify the factors independently associated with in-h...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2016.12.022
更新日期：2017-03-01 00:00:00
abstract：:Monoclonal gammopathy of unknown significance (MGUS) is the most frequent plasma cell disorder that commonly affects elderly patients. Although it is an asymptomatic condition, as well as smoldering myeloma (SMM), the risk of progression to multiple myeloma requiring therapy or other B-cell disorders varies greatly fo...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2018.05.029
更新日期：2018-12-01 00:00:00
abstract：:Cough, a defense mechanism for clearing the airways of secretions, exudate, or foreign bodies, may become a troublesome symptom. Chronic cough, one of the most frequent symptoms requiring medical attention, is often not due to identifiable causes in adults. Chronic productive cough defines chronic bronchitis, and thus...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2020.03.018
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:The prognostic significance of red cell distribution width (RDW) during hospitalization in internal medicine wards was not sufficiently investigated. METHODS:Demographic, clinical and laboratory characteristics were collected from 586 internal medicine inpatients. Following discharge, all-cause mortality wa...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.07.018
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Data on the prevalence of hepatitis C virus (HCV) infection in Italy are outdated and usually derived from studying residents in small towns. METHODS:To assess prevalence of and risk factors for HCV infection among Italian residents in 5 metropolitan areas, subjects ≥20 years of age were randomly selected f...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2018.02.015
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Patients with chronic diseases often receive multiple medications and are associated with increased vulnerability to medication errors. Identifying high-alert medications for them would help to prioritize the interventions with greatest impact for improving medication safety. The aim of this study was to dev...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2014.10.021
更新日期：2014-12-01 00:00:00
abstract：:Anthracosis is a form of pneumoconiosis caused by coal dust or by a smoky and polluted environment. Anthracosis often presents in pulmonary form; only rarely are extrathoracic, esophageal, and mediastinal anthracoses documented. We report a rare case of anthracosis with multiple mediastinal lymphadenopathy. ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2003.09.001
更新日期：2003-11-01 00:00:00
abstract：:We describe an 80-year-old patient who developed Staphylococcus aureus septicemia several days after the implantation of a double stent in the proximal and mid-left anterior descending artery. The infection was complicated by multiple abscesses in the lungs and liver, as well as by bilateral bacterial endophthalmitis ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2004.10.010
更新日期：2005-04-01 00:00:00
abstract：:Enteric fever (EF) is the most common bacteremic disease affecting travelers to the tropics. For more than a decade, fluoroquinolones have been considered the drugs of choice for EF. However, recent reports have raised concern about fluoroquinolone resistance. Treatment with ciprofloxacin failed in a traveler with Sal...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.09.016
更新日期：2007-03-01 00:00:00
abstract：:Obesity, one of the most prevalent health problems in the Western world, is a chronic and progressive condition. Therefore, as with other chronic diseases, patients with obesity require lifelong treatment. Long-term efficacy and effectiveness of obesity treatments is notoriously poor. This may in part be attributable ...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2007.09.011
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:This work aims to evaluate the Minimum Basic Data Set (MBDS) as a data source in the detection of malignant tumors and explore its usefulness as a tool for epidemiological surveillance of cancer. MATERIALS AND METHODS:MBDS hospital data discharge from Prince of Asturias University Hospital (HUPA, Alcalá de H...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2016.06.038
更新日期：2016-10-01 00:00:00
abstract：:In recent years, new concepts of educational theory and practice have stimulated new approaches to medical education in many countries. For various reasons, medical education in Ireland has been slow to change such that there are now increasing concerns about educational standards. In addition, Ireland currently produ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.09.001
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Acute kidney injury (AKI) is a serious complication in patients hospitalized for decompensated heart failure (HF). Currently, AKI definitions consider creatinine levels at admission as reference of baseline renal function (RF). However, renal impairment may already be present at admission. We aimed to study ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.02.028
更新日期：2020-07-01 00:00:00
abstract：AIMS:To validate externally the CACE-HF clinical prediction rule, which predicts 1-year mortality in patients with heart failure (HF). METHODS:We performed an external validation of the CACE-HF risk score in patients included in the RICA heart failure registry who had completed 1 year of follow-up, comparing the chara...
journal_title：European journal of internal medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ejim.2019.05.010
更新日期：2019-08-01 00:00:00
abstract：:Angiomyolipomas are very common in patients with tuberous sclerosis complex (TSC) and cause substantial morbidity. Until now, arterial embolization has been the recommended treatment for symptomatic patients. We report the case of a woman with TSC and giant angiolipomas in whom sirolimus induced a dramatic reduction i...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.07.017
更新日期：2007-01-01 00:00:00
abstract：:Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitan...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2020.01.011
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Upper gastrointestinal bleeding is the severe complication of stress-related mucosal disease in hospitalized patients. In intensive care units (ICU), risk factors are well defined and only mechanical ventilation and coagulopathy proved to be relevant for significant bleeding. On the contrary, in non-ICU sett...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2010.06.010
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:The aims of the present study were to determine both clinical manifestations and outcome of anti-PL7 patients with antisynthetase syndrome (ASS). METHODS:The medical records of 15 consecutive anti-PL7 patients with biopsy proven ASS were retrospectively analyzed without prior selection. RESULTS:Anti-PL7 pa...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2013.01.002
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:According to Swiss legislation, do not attempt cardiopulmonary resuscitation (DNACPR) order can be made at any time by patients only, unless the resuscitation is considered as futile, based on the doctors' evaluation. Little is known about how this decision is made, and which are the factors influencing this...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.04.003
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:The low pharmacological response to phosphodiesterase type 5 inhibitors represents an expression of higher endothelial damage in certain categories of patients with erectile dysfunction and high cardiovascular risk. The present study evaluated this objective in type 2 diabetic patients with erectile dysfunct...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2013.01.001
更新日期：2013-04-01 00:00:00
abstract：:Background: Hyperhomocysteinemia has been accepted as an independent risk factor for atherosclerosis and atherothrombosis. In recent years, several reports have appeared in the literature linking the use of anabolic steroids with acute vascular events in bodybuilders. In this study, we investigated whether hyperhomocy...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00131-x
更新日期：2001-02-01 00:00:00
