Abstract:
OBJECTIVE:This work aims to evaluate the Minimum Basic Data Set (MBDS) as a data source in the detection of malignant tumors and explore its usefulness as a tool for epidemiological surveillance of cancer. MATERIALS AND METHODS:MBDS hospital data discharge from Prince of Asturias University Hospital (HUPA, Alcalá de Henares, Madrid, Spain) and cancer cases recorded in the Hospital Cancer Registry (HCR) have been collected for the period between January 2012 and June 2014. Both databases have been linked by the number of clinical history. For the process of evaluation of MBDS, the types of cancer with more than 100 cases have been analyzed and sensitivity, specificity, positive and negative predictive values(PPV, NPV) of MBDS were calculated using as reference the diagnoses recorded in the HCR. RESULTS:3438 cases of cancer were accounted in the MBDS and 2445 in the HCR. The MBDS has a sensitivity to detect cases of cancer above 60%, although it varies depending on the type of tumor, reaching the highest values for bladder cancer. The specificity and the VPN were very high for all types of cancer studied, always on top of 95%. Finally, the VPP is generally moderate, between 50% and 70%. CONCLUSIONS:The systematic exploitation of the MBDS can provide a valuable tool in the monitoring of cancer by its acceptable sensitivity and high specificity, allowing obtaining information without the delays involved in the consolidation of the annotations of the HCR. Furthermore, its use could partly mitigate the lack of data in important regions of Spain.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Fernández-Navarro P,López-Abente G,Salido-Campos C,Sanz-Anquela JMdoi
10.1016/j.ejim.2016.06.038subject
Has Abstractpub_date
2016-10-01 00:00:00pages
94-97eissn
0953-6205issn
1879-0828pii
S0953-6205(16)30218-7journal_volume
34pub_type
杂志文章abstract:INTRODUCTION:Rituximab induced serum sickness (RISS) is a rare delayed hypersensitivity reaction. The aim of this study was to describe the epidemiological and clinical characteristics of the RISS cases reported in France. METHOD:Serum sickness cases involving rituximab were identified from the French PharmacoVigilanc...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2019.06.009
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND/AIM:The spontaneous preterm birth (SPB) rates in a group of HBeAg-negative chronic HBV infected pregnant women without several known risk factors for preterm delivery as well as the mother to infant HBV transmission rates was evaluated. Moreover the role of maternal data during perinatal period as well as th...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2010.12.005
更新日期:2011-04-01 00:00:00
abstract::The Medical Emergency Team (MET) has enhanced the recognition and response to clinical deterioration in acute healthcare. However, patients reviewed by the MET are at increased risk of in-hospital death. Identifying patients at risk of deterioration may improve patient outcomes. AIM: To identify patient demographic, m...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2019.05.021
更新日期:2019-08-01 00:00:00
abstract::Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2015.02.020
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Data on the prevalence of hepatitis C virus (HCV) infection in Italy are outdated and usually derived from studying residents in small towns. METHODS:To assess prevalence of and risk factors for HCV infection among Italian residents in 5 metropolitan areas, subjects ≥20 years of age were randomly selected f...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2018.02.015
更新日期:2018-07-01 00:00:00
abstract::There is growing evidence suggesting a causative relationship between adrenal adenomas and metabolic and cardiovascular deteriorations. Although demonstrated frequently in subjects with subclinical Cushing Syndrome, subjects with non-functioning adrenal adenomas feature a variety of metabolic and cardiovascular conseq...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2013.02.005
更新日期:2013-09-01 00:00:00
abstract::CHF is a disease of high incidence and prevalence in the elderly. Anemia is associated with an increased mortality in these patients. Erythropoietin secretion is reduced in these patients due to complexed mechanisms. Although some improvement in quality of life has been shown when using ESAs it has not been found any ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.12.011
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:In recent decades, the growing incidence of patients with heart failure who have preserved systolic function, underlines the need to differentiate between heart failure due to diastolic dysfunction and that due to systolic dysfunction. OBJECTIVE:To develop a prediction profile of clinical parameters that en...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.09.001
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Renal dysfunction is associated with increased risk of mortality. The novel Full Age Spectrum (FAS) equations estimating the glomerular filtration rate (GFR) based on serum creatinine (FAScrea) and cystatin C (FAScysC) are validated across the entire age spectrum and are superior markers of renal function co...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2018.02.005
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The Simple Clinical Score (SCS) determined at the time of admission places acutely ill general medical patients into one of five risk classes associated with an increasing risk of death within 30 days. The cohort of acute medical patient that the SCS was derived from had, on average, four combinations of 74 ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.04.012
更新日期:2009-01-01 00:00:00
abstract::BACKGROUND: The aims of this study were to investigate the frequency of halitosis before and after eradication therapy and to determine whether halitosis is a valid indication for eradication therapy in patients with Helicobacter pylori (H. pylori)-positive non-ulcer dyspepsia. METHODS: Dyspepsia, related symptoms, an...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(02)00206-6
更新日期:2003-02-01 00:00:00
abstract::Background: Big cities were particularly affected by tuberculosis in the 1990s. Methods: We studied 141 cases of extrapulmonary tuberculosis in patients not infected by HIV in the northeastern suburbs of Paris. Results: A total of 84 men and 57 women were included in the study. Their average age at diagnosis was 42.2 ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(00)00076-5
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Vascular endothelium activation is a key pathogenic step in systemic inflammatory response syndrome (SIRS) that can be triggered by both microbial and sterile proinflammatory stimuli. The relevance of soluble adhesion molecules as clinical biomarkers to discriminate between infectious and non-infectious SIRS...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2012.10.009
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Whether diabetes mellitus (DM) is associated with a higher risk of perioperative mortality and mortality after liver transplantation (LTx) remains unclear. METHODS:We compared the risk of postoperative mortality and morbidity in DM and non-DM patients undergoing LTx. We enrolled 558 DM patients who underwen...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.05.010
更新日期:2015-07-01 00:00:00
abstract::A 34-year-old man with cystic fibrosis (CF) sustained a bilateral fractured neck of the femur during the course of six grand mal seizures. The fractures were successfully treated with bipolar hemi-arthroplasties. Several risk factors for osteoporosis were present. Bone pathology showed reduced femoral head bone densit...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(03)00036-0
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:The aims of this study were to evaluate the quality of oral anticoagulation (OAC) in AF patients in the practices of general practitioners (GPs) in Germany and to investigate possible causal factors which influence OAC quality. METHODS:We conducted a multi-center, non-interventional, prospective observation...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2013.12.013
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:One of the major threats looming over the growing older population is frailty. It is a distinctive health state characterised by increased vulnerability to internal and external stressors. Although the presence of frailty is well acknowledged, its concept and operationalisation are hampered by the extraordin...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2018.04.023
更新日期:2018-10-01 00:00:00
abstract::Oncogenic osteomalacia (OOM) is a rare but curable cause of metabolic bone disease. We report 9 patients with OOM, including 2 patients with occult nasal sinus tumours and 1 in whom a progressive increase in the post-operative FGF23 level heralded the development of metastatic pulmonary disease. The median duration of...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.01.011
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Antiphospholipid antibodies, the hallmark of the antiphospholipid syndrome, are associated with both venous and arterial thrombosis. Despite some reports stating that this association may be present in patients with low titres of anticardiolipin antibodies, a clear association has only been established in th...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2009.12.010
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVES:To compare serum vitamin D status in older inpatients with bullous pemphigoid (BP) and matched inpatients without BP, and to examine whether hypovitaminosis D, a high comorbidity burden or their combination were associated with BP. METHODS:This prospective case-control study was performed from November 2012...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.02.004
更新日期:2016-06-01 00:00:00
abstract::The use of non-invasive ventilation in patients with community-acquired pneumonia is controversial since this is associated with high rates of treatment failure, compared with other causes of severe acute respiratory failure. The populations of patients with community-acquired pneumonia who have demonstrated better re...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2012.02.011
更新日期:2012-07-01 00:00:00
abstract::Background: We investigated circulating relaxin (RLX) and its potential role in human congestive heart failure (CHF) at rest and after physical exercise. Methods: A total of 10 healthy controls and 35 patients with stable CHF were enrolled in the study. Results: RLX plasma concentrations at rest and after exercise wer...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2003.11.009
更新日期:2004-02-01 00:00:00
abstract::The belief that hospital stays may constitute per se a risk for patients is not widespread among patients and health care professionals. In the balance between advantages and disadvantages of admission, we rarely take into account the impact of the hospital stay itself on the well-being of the patient. In a society th...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.06.003
更新日期:2015-09-01 00:00:00
abstract:BACKGROUNDS:The prognosis and management of left ventricular thrombus (LVT) following acute myocardial infarction (AMI) have not been well evaluated since the advent of primary percutaneous coronary intervention (PCI). We therefore conducted a meta-analysis to assess the prognostic effect of LVT after AMI in primary PC...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2019.10.029
更新日期:2020-03-01 00:00:00
abstract::Of the six known species of Listeria, Listeria monocytogenes is classified as the only human pathogen causing listeriosis, a highly fatal, opportunistic infection contracted via food. Listeria ivanovii is the only other pathogenic species of the genus and is considered to be specific to ruminants, except for extremely...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2005.12.006
更新日期:2006-07-01 00:00:00
abstract:AIM:Dual blockade of renin-angiotensin system (RAS) has increased antiproteinuric effects and it has been increasingly used on patients with proteinuria, but could have secondary effects when this kind of treatment is administered to patients with single functioning kidney. The aim of this study has been to assess the ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.06.002
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:Dopamine agonists are the first line therapy for the treatment of prolactinomas. The aim of this study was to assess the outcome of macroprolactinomas during long-term follow-up after initial treatment with dopamine agonists. DESIGN:Retrospective follow-up study. PATIENTS:We included 72 consecutive patients...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.11.012
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Diabetic patients with renal disease have increased mortality, largely from cardiovascular disease. This could be related to insulin resistance or to other inherited factors. The aim of the present study was to investigate whether there is evidence of the familial aggregation of increased mortality, even in ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2005.07.005
更新日期:2005-11-01 00:00:00
abstract::The International Society of Hypertension (ISH) has recently developed practice guidelines for the management of hypertension in adults aged ≥18 years. Conceptually, the 2020 ISH Guidelines are closer to the 2018 ESC/ESH Guidelines rather than to the 2017 ACC/AHA Guidelines. The ISH Guidelines have two distinctive fea...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2020.09.001
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Few data on patterns of care and outcomes are available for elderly patients with diffuse large B-cell lymphoma (DLBCL) outside of clinical trials. METHODS:We identified patients with DLBCL older than 60 years from a regional cancer registry between 2000 and 2010. Based on registry data and chart review, 12...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2014.05.001
更新日期:2014-07-01 00:00:00