Abstract:
:An acute but transient response to insulin is essential for glucose homeostasis in mammals. Chakraborty et al. (2010) uncover a new feedback mechanism regulating insulin signaling. They show that the inositol pyrophosphate IP7, which is produced in response to insulin, inhibits the Akt kinase, a primary effector of insulin signaling.
journal_name
Celljournal_title
Cellauthors
Manning BDdoi
10.1016/j.cell.2010.11.040subject
Has Abstractpub_date
2010-12-10 00:00:00pages
861-3issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(10)01362-0journal_volume
143pub_type
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