Overexpression of YES1 is associated with favorable prognosis and increased platinum-sensitivity in patients with epithelial ovarian cancer.

abstract：:Cancer is the subject of intense research around the world, but many questions about how the disease works remain unanswered. How exactly does cancer start and how do tumours grow? In fact, at present there are ten times more anticancer drugs being tested in clinical trials than there were 15 years ago. However, many ...

journal_title：Histology and histopathology

authors： Romero-Camarero I,Barajas-Diego M,Castellanos-Martín A,García-Martín Á,Varela G,Abad M,Ludeña MD,Pérez-Losada J,Sánchez-García I

更新日期：2012-02-01 00:00:00

abstract：:The ultrastructure of pinealocytes was studied in rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors which were subjected to experimental manipulations known as enhancers of pineal actions (anosmia, underfeeding or cold exposure). In these animals we found: (I)--more nuclei with deep nuclear invaginations...

journal_title：Histology and histopathology

authors： Cos S,Bardasano JL,Mediavilla MD,Sánchez Barceló EJ

更新日期：1989-04-01 00:00:00

abstract：:Detailed histomorphometric analysis of human conjunctival biopsy specimens has convincingly demonstrated that tissue remodeling of the extracellular matrix (ECM) is an essential and dynamic process associated with conjunctival scarring in ocular cicatricial pemphigoid (OCP). The conjunctival scarring often eventually ...

journal_title：Histology and histopathology

authors： Razzaque MS,Foster CS,Ahmed AR

更新日期：2001-10-01 00:00:00

abstract：:Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possib...

journal_title：Histology and histopathology

authors： Chiang TM

更新日期：1999-04-01 00:00:00

abstract：:To investigate the matrix metalloproteinase (MMP)-9, (MMP)-13, E-Cadherin and Ki-67 expressions in road pavers' skin chronically exposed to bitumen products in order to contribute to a better understanding of the earlier tissue alteration. Skin punch biopsies from 16 daily exposed workers and a control group were stud...

journal_title：Histology and histopathology

authors： Loreto C,Lombardo C,Caltabiano R,Filetti V,Vitale E,Seminara D,Castorina S,Fenga C,Ledda C,Rapisarda V

更新日期：2019-10-01 00:00:00

abstract：:Three-dimensional characteristics of the epithelial cell layer and connective tissue interface of the tongue were studied using scanning electron microscopy. In this study, the fragments of tongue were fixed in modified Karnovsky's fixative solution. Subsequently, the specimens were treated with 10% NaOH solution for ...

journal_title：Histology and histopathology

authors： Silva MC,Watanabe I,Kronka MC

更新日期：2002-04-01 00:00:00

abstract：:Prion diseases are characterized by the accumulation of PrPSc, an altered isoform of a normal cellular protein, PrPc. The prion hypothesis holds that the process of conformational change from PrPc to PrPSc under the influence of PrPSc constitutes the basic infectious mechanism in prion diseases. It is still unknown wh...

journal_title：Histology and histopathology

authors： Brown DR,Kretzschmar HA

更新日期：1997-07-01 00:00:00

abstract：:Close contacts between endocrine insular cells and exocrine acinar, centroacinar and ductular cells occur frequently in the rat pancreas as seen by both light and electron microscopy. Islets of Langerhans are surrounded incompletely by a thin connective tissue capsule or mantle but numerous exocrine-endocrine cell con...

journal_title：Histology and histopathology

authors： Leeson TS,Leeson R

更新日期：1986-01-01 00:00:00

abstract：:Shotgun pellets containing bismuth (Bi) are widely used and may cause a rather intense exposure of some wild animals to Bi. A Bi shotgun pellet was implanted intramuscularly in the triceps surae muscle of 18 adult male Wistar rats. Another group of 9 animals had a Bi shotgun pellet implanted intracranially in the neoc...

journal_title：Histology and histopathology

authors： Stoltenberg M,Locht L,Larsen A,Jensen D,Danscher G

更新日期：2003-07-01 00:00:00

abstract：:The repair of articular cartilage defects is increasingly moving into the focus of experimental and clinical investigations. Histological analysis is the gold standard for a valid and objective evaluation of cartilaginous repair tissue and predominantly relies on the use of established scoring systems. In the past thr...

journal_title：Histology and histopathology

authors： Orth P,Madry H

更新日期：2015-08-01 00:00:00

abstract：:The population of the world grows every year, and life expectancy tends to increase. Thus, long-term preservation of teeth in aged individuals is an urgent issue. The main causes of tooth loss are well known to be periodontitis, caries, fractures, and orthodontic conditions. Although implant placement is a widely acce...

journal_title：Histology and histopathology

authors： Maeda H,Tomokiyo A,Wada N,Koori K,Kawachi G,Akamine A

更新日期：2014-10-01 00:00:00

abstract：:Current data on the localization of neuropeptide Y-related peptides in the hypothalamo-pituitary-adrenal gland (HPA) axis as well as the effects of these peptides on the function of cells comprising HPA axis are presented and discussed. The action of neuropeptide Y, peptide YY, and pancreatic polypeptide on HPA axis a...

journal_title：Histology and histopathology

authors： Malendowicz LK,Markowska A,Zabel M

更新日期：1996-04-01 00:00:00

abstract：:In the present study, morphological changes of the exocrine pancreas in rats after pancreatic duct ligation were examined with light microscopy (hematoxylin-eosin, TUNEL, and PCNA staining) and scanning electron microscopy in order to elucidate the effects of increased pancreatic duct pressure. On the fifth day after ...

journal_title：Histology and histopathology

authors： Hamamoto N,Ashizawa N,Niigaki M,Kaji T,Katsube T,Endoh H,Watanabe M,Sumi S,Kinoshita Y

更新日期：2002-10-01 00:00:00

abstract：:The aim of this study was to demonstrate the morphology and matrix synthesis of embryonic rat liver cells (day 18 of gestation) in organoid cultures (high density cultures) with electron microscopic and immunomorphological techniques. For this purpose the cells of embryonic rat livers were isolated enzymatically and g...

journal_title：Histology and histopathology

authors： Elkasaby A,Xu D,Schröter-Kermani C,Merker HJ

更新日期：1991-04-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD), however, specific treatment for DN has not yet been elucidated. Therefore, it is critically important to understand the molecular mechanism underlying DN to develop cause-related therapeutic strategy. To date, various factors such as hemodyn...

journal_title：Histology and histopathology

authors： Kawanami D,Matoba K,Utsunomiya K

更新日期：2016-10-01 00:00:00

abstract：:Duodenal samples were taken from similar locations in six cats, processed, stained, and examined via light microscope. There were no prominent circular folds (plicae circulares) or stratum compactum (lamina subglandularis). The 1072 microns x 201 microns villi were covered by 46 microns high columnar epitheliocytes pr...

journal_title：Histology and histopathology

authors： Henry RW,al-Bagdadi FK

更新日期：1986-10-01 00:00:00

abstract：:Extracellular matrix of meningiomas was studied by light and electron microscopy with the aid of immunohistochemical techniques. Special attention was paid to the distribution of type I, III, IV, V collagens and laminin with a comparison between meningothelial and fibroblastic types. Connective tissue fibers and basem...

journal_title：Histology and histopathology

authors： Nitta H,Yamashima T,Yamashita J,Kubota T

更新日期：1990-07-01 00:00:00

abstract：:Bone marrow features in stable-phase chronic myelogenous leukemia (CML) are characterized by a striking heterogeneity which is determinable by appropriate means including representative pre-treatment trephine biopsies, immunohistochemistry and morphometry. Cell lineages involved to a variable extent consist not only o...

journal_title：Histology and histopathology

authors： Thiele J,Kvasnicka HM,Fischer R

更新日期：1999-10-01 00:00:00

abstract：:Dimethylnitrosamine (DMN) induced liver injury in rats with cell necrosis, inflammation, hemorrhages, increased collagen type III synthesis and basement membrane component laminin and collagen IV localization in perisinusoidal sites. Malotilate ingestion during DMN treatment abolished inflammation and decreased inters...

journal_title：Histology and histopathology

authors： Stenbäck F,Ala-Kokko L,Ryhänen L

更新日期：1989-01-01 00:00:00

abstract：:The purpose of this study is to visualize topographical changes of serum proteins, albumin and immunoglobulin, passing through mouse glomerular capillary loops and their reabsorption in renal proximal tubules by immunohistochemistry in combination with our "in vivo cryotechnique". The "in vivo cryotechnique" was perfo...

journal_title：Histology and histopathology

authors： Li Z,Terada N,Ohno N,Ohno S

更新日期：2005-07-01 00:00:00

abstract：:It has been commonly supposed that adult stem cells co-localize with supporting cells within specific regions or specialized microenvironment in each tissue/organ, called stem cell niche. This concept was based on the assumption that stem cells are intrinsically hierarchical in nature. However, recent data indicate th...

journal_title：Histology and histopathology

authors： Deregibus MC,Tetta C,Camussi G

更新日期：2010-03-01 00:00:00

abstract：:Androgen receptor (AR) interact with many pathways involved in bladder cancer development and progression. FUS (fused in liposarcoma), a multifunctional protein essential for different cellular processes, has been demonstrated as a key link between androgen receptor signaling and cell-cycle progression in prostate can...

journal_title：Histology and histopathology

authors： Abd Raboh NM,Hakim SA,Abd El Atti RM

更新日期：2020-12-23 00:00:00

abstract：:Targeting essential cellular pathways that determine neuronal and vascular survival can foster a successful therapeutic platform for the treatment of a wide variety of degenerative disorders in the central nervous system. In particular, oxidative cellular injury can precipitate several nervous system disorders that ma...

journal_title：Histology and histopathology

authors： Chong ZZ,Maiese K

更新日期：2004-04-01 00:00:00

abstract：:The present study describes the use of a microwave processing protocol for the rapid histopathological and immunohistochemical diagnosis of bovine rabies. Immunohistochemistry has been used for rabies diagnosis in formalin-fixed tissue with satisfactory results, although the time to diagnosis is considerably longer th...

journal_title：Histology and histopathology

authors： Abreu CC,Nakayama PA,Nogueira CI,Mesquita LP,Lopes PF,Varaschin MS,Seixas Jdo N,Ferreira E,Bezerra PS Jr

更新日期：2012-09-01 00:00:00

abstract：:Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...

journal_title：Histology and histopathology

authors： Lee HW,Lee K,Kim DG,Yang H,Nam DH

更新日期：2016-03-01 00:00:00

abstract：:The photoreceptors of the barred owl (Strix varia) consist of rods, single cones and unequal double cones present in a ratio of about 35:1:3. In the light-adapted condition the rods are of uniform diameter along their entire length and are therefore not felt to undergo photomechanical changes. The rod outer segment co...

journal_title：Histology and histopathology

authors： Braekevelt CR,Smith SA,Smith BJ

更新日期：1996-01-01 00:00:00

abstract：AIMS:Gastric hyperplastic polyps (GHPs) are the most common polypoid lesion of the stomach, and their malignant potential has been demonstrated. In the present study, we evaluated the mucin phenotypes of GHPs and investigated the relationships among mucin phenotypes and clinical-pathological factors, proliferative acti...

journal_title：Histology and histopathology

authors： Li J,Wu LH,Shi Y,Li HM,Song MY,Jiao YF

更新日期：2014-03-01 00:00:00

abstract：:Since bone marrow stromal cells (MSCs) are easily accessible both from healthy donors and patients, and can be expanded on a therapeutic scale, they have attracted attention for cell-based therapy. MSCs contribute to the protection of host tissue after transplantation by Immune modulation and trophic effect. They also...

journal_title：Histology and histopathology

authors： Kitada M,Dezawa M

更新日期：2009-05-01 00:00:00

abstract：:Endometriosis is a chronic pelvic inflammatory process. Local inflammation is known to play a role in pain and infertility associated with the disease, and may be extensively involved in molecular and cellular processes leading to endometriosis development. In this review, we focus on two inflammatory mediators clearl...

journal_title：Histology and histopathology

authors： Defrère S,González-Ramos R,Lousse JC,Colette S,Donnez O,Donnez J,Van Langendonckt A

更新日期：2011-08-01 00:00:00

abstract：:The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors, which plays crucial role in bile acid, cholesterol, lipid and glucose metabolism, as well as in the development of atherosclerosis, intestinal bacterial growth and liver regeneration. FXR is also i...

journal_title：Histology and histopathology

authors： Koutsounas I,Giaginis C,Theocharis S

更新日期：2012-07-01 00:00:00