Identification of human rotavirus serotype by hybridization to polymerase chain reaction-generated probes derived from a hyperdivergent region of the gene encoding outer capsid protein VP7.

abstract：:Relative to wild-type herpes simplex virus type 1 (HSV-1), ICP0-null mutant viruses reactivate inefficiently from explanted, latently infected mouse trigeminal ganglia (TG), indicating that ICP0 is not essential for reactivation but plays a central role in enhancing the efficiency of reactivation. The validity of thes...

journal_title：Journal of virology

authors： Halford WP,Schaffer PA

更新日期：2001-04-01 00:00:00

abstract：:RNA packaging signals (psi) from the 5' ends of murine and avian retroviral genomes have previously been shown to direct encapsidation of heterologous mRNA into the retroviral virion. The avian 5' packaging region has now been further characterized, and we have defined a 270-nucleotide sequence, A psi, which is suffic...

journal_title：Journal of virology

authors： Aronoff R,Hajjar AM,Linial ML

更新日期：1993-01-01 00:00:00

abstract：:The effect of herpes simplex virus type 2 (HSV-2) infection on the synthesis of DNA in human embryonic fibroblast cells was determined at temperatures permissive (37 C) and nonpermissive (42 C) for virus multiplication. During incubation of HSV-2 infected cultures at 42 C for 2 to 4 days or after shift-down from 42 to...

journal_title：Journal of virology

authors： Melvin P,Kucera LS

更新日期：1975-03-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) encodes several proteins that inhibit major histocompatibility complex (MHC) class I-dependent antigen presentation. The HCMV products US2 and US11 are each sufficient for causing the dislocation of human and murine MHC class I heavy chains from the lumen of the endoplasmic reticulum to th...

journal_title：Journal of virology

authors： Rehm A,Engelsberg A,Tortorella D,Körner IJ,Lehmann I,Ploegh HL,Höpken UE

更新日期：2002-05-01 00:00:00

abstract：:This study reports the identification and initial characterization of the precursors, modified forms, and oligomers of bovine herpesvirus 1 (BHV-1) gI and gE proteins with polyvalent rabbit serum specific for gI or gE. Our experiments used the Colorado strain of BHV-1 and mutant viruses with insertions of the Escheric...

journal_title：Journal of virology

authors： Whitbeck JC,Knapp AC,Enquist LW,Lawrence WC,Bello LJ

更新日期：1996-11-01 00:00:00

abstract：:Ebola viruses (EboV) are enveloped RNA viruses infecting cells by a pH-dependent process mediated by viral glycoproteins (GP) involving endocytosis of virions and their routing into acidic endosomes. As with well-characterized pH-dependent viral entry proteins, in particular influenza virus hemagglutinin, it is though...

journal_title：Journal of virology

authors： Bär S,Takada A,Kawaoka Y,Alizon M

更新日期：2006-03-01 00:00:00

abstract：:Small interfering RNAs (siRNAs) processed from double-stranded RNA (dsRNA) of virus origins mediate potent antiviral defense through a process referred to as RNA interference (RNAi) or RNA silencing in diverse organisms. In the simple invertebrate Caenorhabditis elegans, the RNAi process is initiated by a single Dicer...

journal_title：Journal of virology

authors： Guo X,Zhang R,Wang J,Lu R

更新日期：2013-10-01 00:00:00

abstract：:Duck hepatitis B virus mutants containing frameshift or stop codon mutations in a portion of the viral pol gene separating the terminal protein and reverse transcriptase domains had a leaky phenotype and, depending on the location and type of mutation, synthesized up to 10% as much viral DNA as did the wild type. This...

journal_title：Journal of virology

authors： Wu TT,Condreay LD,Coates L,Aldrich C,Mason W

更新日期：1991-05-01 00:00:00

abstract：:Simian virus 40 (SV40) growth on rhesus kidney cells and on the T-22 line of SV40-transformed green monkey kidney (GMK) cells is largely limited by the low plating efficiency of SV40 on these cells. In addition, a fraction of the rhesus kidney and T-22 cells are resistant to infection by SV40. Nevertheless, 72-h viral...

journal_title：Journal of virology

authors： Norkin LC,Ouellette J

更新日期：1976-04-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) integrase protein (IN) catalyzes two reactions required to integrate HIV DNA into the human genome: 3' processing of the viral DNA ends and integration. IN has three domains, the N-terminal zinc-binding domain, the catalytic core, and the C-terminal SH3 domain. Previously, it was...

journal_title：Journal of virology

authors： van den Ent FM,Vos A,Plasterk RH

更新日期：1999-04-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) LANA is an 1,162-amino-acid protein that tethers terminal repeat (TR) DNA to mitotic chromosomes to mediate episome persistence in dividing cells. C-terminal LANA self-associates to bind TR DNA. LANA contains independent N- and C-terminal chromosome binding regions. N-ter...

journal_title：Journal of virology

authors： Kelley-Clarke B,De Leon-Vazquez E,Slain K,Barbera AJ,Kaye KM

更新日期：2009-05-01 00:00:00

abstract：:Thogoto virus (THOV) is a tick-transmitted orthomyxovirus with a genome consisting of six negative-stranded RNA segments. To rescue a recombinant THOV, the viral structural proteins were produced from expression plasmids by means of a vaccinia virus expressing the T7 RNA polymerase. Genomic virus RNAs (vRNAs) were gen...

journal_title：Journal of virology

authors： Wagner E,Engelhardt OG,Gruber S,Haller O,Kochs G

更新日期：2001-10-01 00:00:00

abstract：:To analyze the biological activities of the alphavirus glycoproteins, eight different monoclonal antibodies against the two glycoproteins of western equine encephalitis virus were isolated. Five of the eight monoclonal antibodies were shown to be specific for E1 and three for E2 protein by an enzyme-linked immunosorbe...

journal_title：Journal of virology

authors： Yamamoto K,Hashimoto K,Chiba J,Simizu B

更新日期：1985-09-01 00:00:00

abstract：:Many viruses have evolved mechanisms to evade the repression of translation mediated by protein kinase R (PKR). In the case of murine cytomegalovirus (MCMV), the protein products of two essential genes, m142 and m143, bind to double-stranded RNA (dsRNA) and block phosphorylation of PKR and eukaryotic initiation factor...

journal_title：Journal of virology

authors： Child SJ,Geballe AP

更新日期：2009-02-01 00:00:00

abstract：:Pestiviruses prevent alpha/beta interferon (IFN-alpha/beta) production by promoting proteasomal degradation of interferon regulatory factor 3 (IRF3) by means of the viral N(pro) nonstructural protein. N(pro) is also an autoprotease, and its amino-terminal coding sequence is involved in translation initiation. We previ...

journal_title：Journal of virology

authors： Ruggli N,Summerfield A,Fiebach AR,Guzylack-Piriou L,Bauhofer O,Lamm CG,Waltersperger S,Matsuno K,Liu L,Gerber M,Choi KH,Hofmann MA,Sakoda Y,Tratschin JD

更新日期：2009-01-01 00:00:00

abstract：:Apoptosis of infected cells is critically involved in antiviral defense. Apoptosis, however, may also support the release and spread of viruses. Although the elimination of infected hepatocytes is required to combat hepatitis B virus (HBV) infection, it is still unknown which consequences hepatocyte apoptosis has for ...

journal_title：Journal of virology

authors： Arzberger S,Hösel M,Protzer U

更新日期：2010-11-01 00:00:00

abstract：:Purified nuclei from polyoma-infected mouse (3T3) cells were found to be greatly reduced in their ability to synthesize viral DNA in vitro when compared with a crude system consisting of an unfractionated hypotonic lysate of the infected cells. The synthetic capacity of the nuclei could be fully reconstituted when a h...

journal_title：Journal of virology

authors： Francke B,Hunter T

更新日期：1975-01-01 00:00:00

abstract：:Recombinant vaccinia viruses expressing C-terminally truncated E's that ranged in length from 9 to 99% of the N-terminal sequence were constructed. The overall antigenicity of the E products was analyzed by radioimmunoprecipitation, using dengue virus hyperimmune mouse ascitic fluid (HMAF) or an anti-E peptide serum. ...

journal_title：Journal of virology

authors： Men RH,Bray M,Lai CJ

更新日期：1991-03-01 00:00:00

abstract：:Since 2005, a large poliomyelitis outbreak associated with type 2 circulating vaccine-derived poliovirus (cVDPV2) has occurred in northern Nigeria, where immunization coverage with trivalent oral poliovirus vaccine (tOPV) has been low. Phylogenetic analysis of P1/capsid region sequences of isolates from each of the 40...

journal_title：Journal of virology

authors： Burns CC,Shaw J,Jorba J,Bukbuk D,Adu F,Gumede N,Pate MA,Abanida EA,Gasasira A,Iber J,Chen Q,Vincent A,Chenoweth P,Henderson E,Wannemuehler K,Naeem A,Umami RN,Nishimura Y,Shimizu H,Baba M,Adeniji A,Williams AJ,

更新日期：2013-05-01 00:00:00

abstract：:The vaccinia virus H2R gene (VACWR 100) is conserved in all sequenced members of the poxvirus family and encodes a protein with a predicted transmembrane domain and four invariant cysteines. A recombinant vaccinia virus, in which expression of the H2 protein is stringently regulated, was unable to replicate without in...

journal_title：Journal of virology

authors： Senkevich TG,Moss B

更新日期：2005-04-01 00:00:00

abstract：:Influenza viruses resistant to the neuraminidase (NA) inhibitor oseltamivir arise under drug selection pressure both in vitro and in vivo. Several mutations in the active site of the viral NA are known to confer relative resistance to oseltamivir, and influenza viruses with certain oseltamivir resistance mutations hav...

journal_title：Journal of virology

authors： Bouvier NM,Lowen AC,Palese P

更新日期：2008-10-01 00:00:00

abstract：UNLABELLED:Based on an explant reactivation model, it has been proposed that CD8(+) T cells maintain latency in trigeminal ganglia (TG) of mice latently infected with herpes simplex virus 1 (HSV-1) [T. Liu, K. M. Khanna, X. Chen, D. J. Fink, and R. L. Hendricks, J Exp Med 191:1459-1466, 2000, doi:10.1084/jem.191.9.1459...

journal_title：Journal of virology

authors： Mott KR,Gate D,Matundan HH,Ghiasi YN,Town T,Ghiasi H

更新日期：2016-04-29 00:00:00

abstract：:Herpes simplex virus 1 genome consists of two covalently linked components, L and S, that invert relative to each other to yield four equimolar isomeric populations designated P (prototype), Is (inversion of S component), Il (inversion of L component), and Ils (inversion of L and S components) differing in the orienta...

journal_title：Journal of virology

authors： Jenkins FJ,Roizman B

更新日期：1986-08-01 00:00:00

abstract：:A map of bacteriophage lambda was constructed, including accurate positions for all 41 cut sites made by 12 different restriction enzymes. Over 100 fragments from single, multiple, and partial enzyme digestions were measured versus standards that were calibrated with respect to DNA molecules of known sequence. The dat...

journal_title：Journal of virology

authors： Daniels DL,de Wet JR,Blattner FR

更新日期：1980-01-01 00:00:00

abstract：:The association of newly synthesized vesicular stomatitis virus proteins into nucleocapsid structures was examined in a cell-free system that supports concurrent viral protein synthesis, transcription, and RNA replication. The vesicular stomatitis virus proteins synthesized by this system associated with the newly rep...

journal_title：Journal of virology

authors： Patton JT,Davis NL,Wertz GW

更新日期：1983-01-01 00:00:00

abstract：:We used 18 monoclonal antibodies against B19 parvovirus to identify neutralizing epitopes on the viral capsid. Of the 18 antibodies, 9 had in vitro neutralizing activity in a bone marrow colony culture assay. The overlapping polypeptide fragments spanning the B19 structural proteins were produced in a pMAL-c Escherich...

journal_title：Journal of virology

authors： Yoshimoto K,Rosenfeld S,Frickhofen N,Kennedy D,Hills R,Kajigaya S,Young NS

更新日期：1991-12-01 00:00:00

abstract：:We have investigated the mechanism of duck hepatitis B virus (DHBV) entry into susceptible primary duck hepatocytes (PDHs), using mutants of carboxypeptidase D (gp180), a transmembrane protein shown to act as the primary cellular receptor for avian hepatitis B virus uptake. The variant proteins were abundantly produce...

journal_title：Journal of virology

authors： Breiner KM,Schaller H

更新日期：2000-03-01 00:00:00

abstract：:It has been suggested that sequences located within the 5' noncoding region of human foamy virus (HFV) are critical for expression of the viral Gag and Pol structural proteins. Here, we identify a discrete approximately 151-nucleotide sequence, located within the R region of the HFV long terminal repeat, that activate...

journal_title：Journal of virology

authors： Russell RA,Zeng Y,Erlwein O,Cullen BR,McClure MO

更新日期：2001-08-01 00:00:00

abstract：:Apoptosis of neurons and astrocytes is induced by human immunodeficiency type 1 (HIV-1) infection in vitro and has been demonstrated in brain tissue from patients with AIDS. We analyzed a panel of diverse HIV-1 primary isolates for the ability to replicate and induce neuronal and astrocyte apoptosis in primary human b...

journal_title：Journal of virology

authors： Ohagen A,Ghosh S,He J,Huang K,Chen Y,Yuan M,Osathanondh R,Gartner S,Shi B,Shaw G,Gabuzda D

更新日期：1999-02-01 00:00:00

abstract：:The src genes of different Rous sarcoma virus (RSV) strains have been reported to be highly conserved by some investigators using RNA-cDNA hybridization, whereas others using oligonucleotide, peptide, and serological analyses have judged src genes to be variable in 30 to 50% of the respective markers. Moreover, distin...

journal_title：Journal of virology

authors： Lee WH,Nunn M,Duesberg PH

更新日期：1981-09-01 00:00:00