Editorial: Mechanistic underpinnings of stem cell therapy for neurological disorders.

abstract：:To understand the role of hypothalamic dopamine in thermoregulation, single unit activity was recorded in vitro, from constantly perfused tissue slices of rat preoptic area and anterior hypothalamus, PO/AH. The firing rate and thermosensitivity of individual PO/AH neurons were determined before, during and after tissu...

journal_title：Brain research

authors： Scott IM,Boulant JA

更新日期：1984-07-23 00:00:00

abstract：:As a means of probing the chemotransducer, impulse sequences from in vitro, superfused sinus nerve-carotid body preparations were analyzed for departures from randomness. Twelve of 17 spike trains showed interval histograms that did not differ significantly from exponential. Thus these sequences resembled a Poisson (r...

journal_title：Brain research

authors： Nolan WF,Donnelly DF,Smith EJ,Dutton RE

更新日期：1984-01-30 00:00:00

abstract：:Gonadal steroids have previously been shown to enhance neuritic outgrowth from mouse preoptic area explants in vitro. To examine effects within the explant proper, dendritic fields of Golgi-stained neurons of estradiol-treated and untreated cultures were compared quantitatively. Neurons of gonadal steroid-treated cult...

journal_title：Brain research

authors： Toran-Allerand CD,Hashimoto K,Greenough WT,Saltarelli M

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:Hypoxia is a critical secondary injury mechanism in traumatic brain injury (TBI), and early intervention to alleviate post-TBI hypoxia may be beneficial. NVX-108, a dodecafluoropentane perfluorocarbon, was screened for its ability to increase brain tissue oxygen tension (PbtO2) when administered soon after T...

journal_title：Brain research

authors： Mullah SH,Saha BK,Abutarboush R,Walker PB,Haque A,Arnaud FG,Hazzard B,Auker CR,McCarron RM,Scultetus AH,Moon-Massat P

更新日期：2016-03-01 00:00:00

abstract：:Extracellular recordings from the supraoptic nucleus of the rat established that vasopressinergic neurosecretory cells were excited by stimulation of cervical but not abdominal vagal afferents. This response was absent or significantly attenuated after microinjection of gamma-aminobutyric acid into a region of the cau...

journal_title：Brain research

authors： Day TA,Sibbald JR,Smith DW

更新日期：1992-10-30 00:00:00

abstract：:Despite significant advancements in the understanding of the pathophysiological mechanisms of subarachnoid hemorrhage (SAH), little is known about the emotional consequences. The primary goal of this study was to describe the locomotor and behavioral patterns in rats following both a single-injection and double-inject...

journal_title：Brain research

authors： Boyko M,Azab AN,Kuts R,Gruenbaum BF,Gruenbaum SE,Melamed I,Brotfain E,Shapira Y,Cesnulis E,Zlotnik A

更新日期：2013-01-23 00:00:00

abstract：:The effects of two kinds of antibiotics, minocycline (MNC) and ampicillin (AB-PC), on human sleep were investigated on 19 healthy male students to test for a relationship between human sleep and protein synthesis. These drugs and placebos were capsulated identically in appearance and were given to the subjects using t...

journal_title：Brain research

authors： Nonaka K,Nakazawa Y,Kotorii T

更新日期：1983-12-12 00:00:00

abstract：:Fos expression in the globus pallidus (GP) of rats was elicited by the D2 agonist quinpirole both ipsilateral and contralateral to a unilateral nigrostriatal 6-hydroxydopamine (6-OHDA) injection; however, the 6-OHDA-treated hemisphere was more sensitive to this effect. The quinpirole-induced GP Fos expression was anta...

journal_title：Brain research

authors： Marshall JF,Cole BN,LaHoste GJ

更新日期：1993-12-31 00:00:00

abstract：:This experiment was performed in order to examine several of the underlying mechanisms by which the septal area and adjacent regions regulate quiet biting attack behavior elicited from electrical stimulation of the hypothalamus in the cat. The results clearly indicate that stimulation of the septal area and anterior c...

journal_title：Brain research

authors： Brutus M,Shaikh MB,Siegel HE,Siegel A

更新日期：1984-09-24 00:00:00

abstract：:Peripheral nerve fascicles are deliberately impaled during microneurography experiments. We have assessed conduction block under these circumstances. First we recorded compound action potentials (CAP) in the sural nerve following stimulation of the sciatic nerve. The insertion of injection and microneurography electro...

journal_title：Brain research

authors： Rice AS,McMahon SB,Wall PD

更新日期：1993-12-24 00:00:00

abstract：:Spontaneously firing units were recorded extracellularly from the hippocampus of anesthetized rats, and autocorrelograms were conventionally constructed. These conventional autocorrelograms were sorted into frequency-specific autocorrelograms according to the instantaneous firing frequency of the spike at Deltat=0, wh...

journal_title：Brain research

authors： Murata M,Kato N

更新日期：2007-02-16 00:00:00

abstract：:Fetal mouse retinal ganglion cell axons have been shown to ramify within co-cultured basement membrane secreting tumor explants and upon isolated basement membranes. Here we report that laminin, a glycoprotein found in basement membranes and adhesion sites of a variety of cell types, acted as a substrate for retinal e...

journal_title：Brain research

authors： Smalheiser NR,Crain SM,Reid LM

更新日期：1984-01-01 00:00:00

abstract：:Opioid antagonists block the positive hedonic response to food taste and are potent inhibitors of palatability-driven feeding. However, the specific brain regions within which opioid peptide secretion contributes to the maintenance of palatability-driven feeding have not been clearly established. In the present study,...

journal_title：Brain research

authors： Park TH,Carr KD

更新日期：1998-09-14 00:00:00

abstract：:The aim of this work was to study whether the vestibular afferent fibers establish direct connections with the motoneurons of glossopharyngeal and vagus nerves of the frog, Rana esculenta. In anaesthetized animals the vestibulocochlear nerve and the common root of glossopharyngeal-vagus and accessory (IX-X-XI) nerves ...

journal_title：Brain research

authors： Deák A,Bácskai T,Veress G,Matesz C

更新日期：2009-08-25 00:00:00

abstract：BACKGROUND:An important part of the medical treatment of many cerebrovascular diseases is the occlusion of brain supplying arteries. Until now, the risk of this intervention can only be estimated by invasive diagnostics including the risk of cerebrovascular accidents. METHODS AND RESULTS:As a supporting tool, a comput...

journal_title：Brain research

authors： Roessler FC,Reith W,Siegel G

更新日期：2006-11-06 00:00:00

abstract：:The effect of hypoxia on the structure and function of the synaptosomal membranes and myelin fraction (glial cells, neuronal cells bodies and axonal membranes) was investigated by measuring Na+,K(+)-ATPase activity and levels of lipid peroxidation products in cerebral cortical synaptosomal membranes and myelin fractio...

journal_title：Brain research

authors： Razdan B,Marro PJ,Tammela O,Goel R,Mishra OP,Delivoria-Papadopoulos M

更新日期：1993-01-15 00:00:00

abstract：:Freeze-fracture examination of nodes of Ranvier from adult rat optic nerve demonstrates the presence of astrocytic processes at the majority of nodes of Ranvier. Astrocytic processes often run along the entire length of the nodal gap, although they do not necessarily encircle the entire nodal circumference. The E- and...

journal_title：Brain research

authors： Waxman SG,Black JA

更新日期：1984-08-06 00:00:00

abstract：:The presynaptic neurotoxin omega-conotoxin (omega-CgTx) was tested for its ability to inhibit voltage-dependent calcium flux and transmitter release in rat brain synaptosomes. Conotoxin (0.001-10 microM) had no effect on calcium uptake or endogenous dopamine release from rat striatal synaptosomes in the absence of pot...

journal_title：Brain research

authors： Woodward JJ,Rezazadeh SM,Leslie SW

更新日期：1988-12-13 00:00:00

abstract：:An in vitro method was developed to separately visualize dopaminergic, noradrenergic and serotoninergic terminals in the cerebral, hippocampal and cerebellar cortices of the rat, by means of the glyoxylic histochemical fluorescence method. Animals were pretreated with alpha-methylparatyrosine to deplete catecholamine ...

journal_title：Brain research

authors： Berger B,Glowinski J

更新日期：1978-05-19 00:00:00

abstract：:The monoclonal antibody E/C8 was originally generated against chicken dorsal root ganglia. The antigen detected by E/C8, NAPA-73, is an intermediate filament-associated protein. NAPA-73 was shown to be one of the earliest neuronal markers to appear during development since it appears in some neuronal precursor cells o...

journal_title：Brain research

authors： Wu DK,de Vellis J

更新日期：1987-09-22 00:00:00

abstract：:Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...

journal_title：Brain research

authors： Amorim P,Cottrell JE,Kass IS

更新日期：1999-10-09 00:00:00

abstract：:Ongoing electrical activity was recorded from the axons of neurosecretory cells from the brain of 5th instar Rhodnius prolixus throughout the moulting cycle. Dramatic changes in both the frequency and pattern of electrical activity occur at specific times during the cycle, enabling the timing of release of neurohormon...

journal_title：Brain research

authors： Orchard I,Steel CG

更新日期：1980-06-02 00:00:00

abstract：:The primate somatosensory neuraxis provides a highly translational model system with which to investigate adult neural plasticity. Here, we report immunohistochemical staining data for AMPA and GABAA/B receptor subunits of area 3b cortex and cuneate nucleus of adult squirrel monkeys one to five years after median and ...

journal_title：Brain research

authors： Mowery TM,Sarin RM,Kostylev PV,Garraghty PE

更新日期：2015-06-22 00:00:00

abstract：:The distribution of avian pancreatic polypeptide (APP)-like immunoreactivity (APP-IR) in the chicken retina was investigated by means of immunohistochemistry. The observation from frozen sections showed that APP-IR is localized in the stratified amacrine cells of the first sublayer. Examination of whole-mounts reveale...

journal_title：Brain research

authors： Katayama Y,Kiyama H,Arai Y,Tohyama M

更新日期：1984-09-17 00:00:00

abstract：:To investigate the possible GABAergic nature of somatostatin-immunoreactive neurons of the larval tiger salamander retina, somatostatin immunocytochemistry was combined with either gamma-aminobutyric acid (GABA) immunocytochemistry or autoradiography of GABA high-affinity uptake. A total of 1,062 somatostatin cells we...

journal_title：Brain research

authors： Watt CB,Florack VJ

更新日期：1993-07-16 00:00:00

abstract：:The cerebellum and inferior olive of adult homozygous leaner mutant mice (tgIa/tgIa) were examined using anti-vitamin D-dependent calcium binding protein immunohistochemistry, and Nissl staining. The immunohistochemical staining revealed that cerebellar Purkinje cell loss in leaner is restricted to alternating saggita...

journal_title：Brain research

authors： Heckroth JA,Abbott LC

更新日期：1994-09-26 00:00:00

abstract：:The behaviour and cognitive abilities of marmosets with bilateral ablations of either the archicortex on the mediodorsal surface or the paleocortex on the ventrolateral surface of the frontal lobes were assessed in terms of the types of information being handled, the mode of action (inhibitory versus productive mechan...

journal_title：Brain research

authors： Ridley RM,Durnford LJ,Baker JA,Baker HF

更新日期：1993-11-19 00:00:00

abstract：:We have previously shown that prolonged preganglionic stimulation (e.g. 40 Hz 20 min) depletes the neurotensin (NT) store of preganglionic axon terminals in the stellate ganglion (SG) of the cat and that replenishment of the store requires several days. The present study investigates the mechanisms which control turno...

journal_title：Brain research

authors： Maher E,Bachoo B,Polosa C

更新日期：1994-03-21 00:00:00

abstract：:Lifelong bilingualism is associated with the delayed diagnosis of dementia, suggesting bilingual experience is relevant to brain health in aging. While the effects of bilingualism on cognitive functions across the lifespan are well documented, less is known about the neural substrates underlying differential behaviour...

journal_title：Brain research

authors： Olsen RK,Pangelinan MM,Bogulski C,Chakravarty MM,Luk G,Grady CL,Bialystok E

更新日期：2015-07-01 00:00:00

abstract：:Previous studies have suggested that monosynaptic transmission between spinal primary afferent fibers and motoneurons is mediated by an excitatory amino acid, most likely glutamate or aspartate. No such comparable studies have been carried out in the trigeminal system. In an attempt to elucidate the neurotransmitter(s...

journal_title：Brain research

authors： Chandler SH

更新日期：1989-01-16 00:00:00