The expression of cyclin G in nasopharyngeal carcinoma and its significance.

abstract：:Hereditary periodic fever syndromes (HPF) are a group of diseases characterised by recurrences of fever and inflammation separated by symptom-free intervals. Familial Mediterranean fever (FMF) is the most frequent entity within this group of disorders which further consists of hyperimmunoglobulinaemia D and periodic f...

journal_title：Clinical and experimental medicine

authors： van der Hilst JC,Simon A,Drenth JP

更新日期：2005-10-01 00:00:00

abstract：:Oxidative stress (OS) has recently been documented in hypothyroidism, a disease more prevalent in women. In general, OS is reported to be more prevalent in males. However, the effect of gender on OS and protein glycation in hypothyroidism has not been addressed. Blood samples from 37 recently diagnosed primary hypothy...

journal_title：Clinical and experimental medicine

authors： Nanda N,Bobby Z,Hamide A

更新日期：2008-06-01 00:00:00

abstract：:T helper (Th) 17 cells have a critical role in the pathogenesis of chronic hepatitis B virus (HBV) infection, and basic leucine zipper transcription factor, ATF-like (BATF) is a newly identified transcriptional factor regulating the differentiation of Th17 cells. However, its precise role in patients with chronic hepa...

journal_title：Clinical and experimental medicine

authors： Wang LY,Fan YC,Zhao J,Ji XF,Wang K

更新日期：2018-05-01 00:00:00

abstract：:Experimental, epidemiologic, and clinical trial data indicate the antineoplastic effects of calcium and vitamin D in large-bowel neoplasia. The aim of this study was to determine serum levels of vitamin D metabolites and parathormone (PTH) in patients with colorectal cancer (CRC) and to extract conclusions comparing t...

journal_title：Clinical and experimental medicine

authors： Charalampopoulos A,Charalabopoulos A,Batistatou A,Golias C,Anogeianaki A,Peschos D,Iliadis I,Macheras A,Charalabopoulos K

更新日期：2010-03-01 00:00:00

abstract：:Nitric oxide (NO), produced by the nitric oxide synthase (iNOS) enzyme, is the most-important molecule responsible for the killing of Leishmania parasites by macrophages. In previous work we have demonstrated that, after activation with recombinant human interferon-gamma and/or bacterial lipopolysaccharide, human macr...

journal_title：Clinical and experimental medicine

authors： Panaro MA,Brandonisio O,Sisto M,Acquafredda A,Leogrande D,Fumarola L,Mitolo V

更新日期：2001-09-01 00:00:00

abstract：:Anti-inflammatory cytokine and its serological detection may have an important role in the process of cardiovascular and cerebrovascular diseases. We investigated whether serum interleukin-10 (IL-10) is associated with cerebral infarction or not in the general population. Identified comprehensive searching was perform...

journal_title：Clinical and experimental medicine

authors： Diao ZY,Wang CL,Qi HS,Jia GY,Yan CZ

更新日期：2016-05-01 00:00:00

abstract：:Arginase activity was measured in serum and biopsy from healthy individuals and colorectal cancer patients. Arginase activity in tumor samples (87 +/- 7.7 U/g tissue) was significantly higher than in controls (40.7 +/- 3.3 U/g tissue). However, serum arginase activity did not show any significant change in both groups...

journal_title：Clinical and experimental medicine

authors： del Ara RM,González-Polo RA,Caro A,del Amo E,Palomo L,Hernández E,Soler G,Fuentes JM

更新日期：2002-05-01 00:00:00

abstract：:Breast cancer is the most common cause of malignancy and mortality in women worldwide. This study aimed at localising homologous recombination repair (HR) genes and their chromosomal loci and correlating their nucleotide variants with susceptibility to breast cancer. In this study, authors analysed the association bet...

journal_title：Clinical and experimental medicine

authors： Romanowicz H,Strapagiel D,Słomka M,Sobalska-Kwapis M,Kępka E,Siewierska-Górska A,Zadrożny M,Bieńkiewicz J,Smolarz B

更新日期：2017-11-01 00:00:00

abstract：:Twist1 is a key transcription factor, which confers tumor cells with cancer stem cell (CSC)-like characteristics and enhances epithelial-mesenchymal transition in pathological conditions including tumor malignancy and metastasis. This study aimed to evaluate the expression patterns and clinical significance of Twist1 ...

journal_title：Clinical and experimental medicine

authors： Rasti A,Madjd Z,Abolhasani M,Mehrazma M,Janani L,Saeednejad Zanjani L,Asgari M

更新日期：2018-05-01 00:00:00

abstract：:The aim of this study was to discover potential biomarkers for rheumatoid arthritis (RA) using Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with magnetic beads. Proteomic fingerprint technology combining magnetic beads with MALDI-TOF-MS was used to profile and compare the prote...

journal_title：Clinical and experimental medicine

authors： Zhang X,Yuan Z,Shen B,Zhu M,Liu C,Xu W

更新日期：2012-09-01 00:00:00

abstract：:It is suggested that gastric mucins, and in particular some specific glycan structures that can act as carbohydrate receptors, are involved in the interactions with Helicobacter pylori adhesins. The main aim of our study was to evaluate glycosylation pattern of glycoproteins of gastric juice before and at the end of e...

journal_title：Clinical and experimental medicine

authors： Radziejewska I,Borzym-Kluczyk M,Namiot Z,Stefańska E

更新日期：2011-06-01 00:00:00

abstract：:To evaluate potency and safety of 14-day bismuth-furazolidone quadruple regimens and to compare efficacies of five proton pump inhibitors (PPIs) for the initial eradication of Helicobacter pylori (H. pylori), 175 eligible patients were enrolled and randomly assigned to 14-day quadruple regimens consisting of bismuth (...

journal_title：Clinical and experimental medicine

authors： Chen L,He J,Wang L,Ge Q,Chu H,Chen Y,Chen X,Long Y,Deng Y,He H,Li A,Chen S

更新日期：2018-11-01 00:00:00

abstract：:Tumor markers were used for disease monitoring in small-cell lung cancer patients. The aim of this study was to improve diagnostic efficiency in the detection of tumor progression in small-cell lung cancer patients by using fuzzy logic modeling in combination with a tumor marker panel (NSE, ProGRP, Tumor M2-PK, CYFRA ...

journal_title：Clinical and experimental medicine

authors： Schneider J,Peltri G,Bitterlich N,Philipp M,Velcovsky HG,Morr H,Katz N,Eigenbrodt E

更新日期：2003-02-01 00:00:00

abstract：:Although the role of cholesterol absorption by the gallbladder epithelium in gallstone formation is well established, the exact process is poorly understood. Potential candidates for regulation of transepithelial cholesterol transport are suggested to be two large membrane multiple ligand receptors, megalin and cubili...

journal_title：Clinical and experimental medicine

authors： Tsaroucha AK,Chatzaki E,Lambropoulou M,Despoudi K,Laftsidis P,Charsou C,Polychronidis A,Papadopoulos N,Simopoulos CE

更新日期：2008-09-01 00:00:00

abstract：:Catastrophic antiphospholipid syndrome (CAPS) is a rare disorder, characterized by the development of multiple vascular thrombosis over a short period of time, in patients with persistently detectable antiphospholipid antibodies (aPLs). The vascular occlusions predominantly affect small vessels. The overall mortality ...

journal_title：Clinical and experimental medicine

authors： Tinti MG,Carnevale V,Inglese M,Molinaro F,Bernal M,Migliore A,De Cata A

更新日期：2019-08-01 00:00:00

abstract：:The most important mutation associated with Multiple Endocrine Neoplasia type 2B (MEN 2B) is the change of thymine to cytosine in codon 918 of exon 16 in the RET oncogene (ATG → ACG). The aim of this work was to develop a single oligoarray by using tandem hybridization to detect the T918C/RET mutation for MEN 2B patie...

journal_title：Clinical and experimental medicine

authors： Pacheco-Rivera RA,Hernández-Zamora E,González-Yebra B,Beattie K,Maldonado-Rodríguez R,Santiago-Hernández JC,Medrano-Ortiz de Zárate ME,Salcedo M

更新日期：2011-12-01 00:00:00

abstract：:The aim of this work was to investigate the presence of the RHD gene in fetal cells obtained from amniotic fluid. We studied 65 samples of amniotic fluid, 11 from RhD-negative mothers sensitized with anti-D alloantibodies. The fetal origin of the DNA was confirmed with the analysis of 1 VNTR locus and 3 STR loci in DN...

journal_title：Clinical and experimental medicine

authors： Cotorruelo C,Biondi C,García Borrás S,Di Mónaco R,Racca A

更新日期：2002-07-01 00:00:00

abstract：:We have recently found that pigment epithelium-derived factor (PEDF), a glycoprotein with potent neuronal differentiating activity, not only inhibits endothelial cell damage, smooth muscle cell proliferation and platelet aggregation in vitro, but also suppresses occlusive thrombus formation in rats. These observations...

journal_title：Clinical and experimental medicine

authors： Yamagishi S,Matsui T,Nakamura K,Takenaka K

更新日期：2009-03-01 00:00:00

abstract：:TNF-α plays a key role in the inflammatory cytokine cascade involved in the pathogenesis of chronic arthritis, including rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Systemic inflammation and the increased production of pro-inflammatory cytokines in these patients may favor the onset of metab...

journal_title：Clinical and experimental medicine

authors： Maruotti N,d'Onofrio F,Cantatore FP

更新日期：2015-11-01 00:00:00

abstract：:The sensitivity of the alkaline comet assay for the evaluation of baseline and treatment-induced DNA damage in white blood cells of breast cancer patients receiving adjuvant chemotherapy according to three conventional anthracycline- and cyclophosphamide-containing protocols was investigated. Additionally, baseline DN...

journal_title：Clinical and experimental medicine

authors： Kopjar N,Milas I,Garaj-Vrhovac V,Gamulin M

更新日期：2006-12-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) has been linked with tumor invasion and metastasis. However, the role of VEGF expression in osteosarcoma remains controversial. By searching the PubMed, Embase, and Google Scholar databases, we conducted a meta-analysis to evaluate the pathological and prognostic significance ...

journal_title：Clinical and experimental medicine

authors： Han G,Wang Y,Bi W,Jia J,Wang W,Xu M

更新日期：2016-11-01 00:00:00

abstract：:Increased expression of progranulin (PGRN) has been reported in some hematological cancers, but limited information regarding its significance in acute lymphoblastic leukemia (ALL) is available. This study involved 60 subjects (40 de novo adult ALL patients and 20 controls). Serum PGRN level was measured by enzyme-lin...

journal_title：Clinical and experimental medicine

authors： El-Ghammaz AMS,Azzazi MO,Mostafa N,Hegab HM,Mahmoud AA

更新日期：2020-05-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a very common head and neck cancer in southern china. Despite advances in surgical and chemotherapeutic approaches, its prognosis is still not promising. Hedgehog signaling pathway was reported to be involved in a number of cancers including head and neck. However, it remains unclear ...

journal_title：Clinical and experimental medicine

authors： Yue Y,Zhong W,Pei G,Xiao B,Zhang G,Jiang F,Zhang J,Chen C,Yang P,Dang H,Chang H

更新日期：2013-11-01 00:00:00

abstract：:The rat is an established model for studying intestinal adaptations following abdominal surgery. In the study of functional and morphological adaptations of the small intestine, it is helpful to estimate the mucosal surface area. In order to simplify measurements and calculation we developed a new mathematical model f...

journal_title：Clinical and experimental medicine

authors： Kisielinski K,Willis S,Prescher A,Klosterhalfen B,Schumpelick V

更新日期：2002-11-01 00:00:00

abstract：:Chronic infection with hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality throughout the world. Although reliable figures regarding the global prevalence of HCV infection are wanting, it is likely that HCV prevalence will continue to increase. Injection drug use is the most important s...

journal_title：Clinical and experimental medicine

authors： Herrine SK,Rossi S,Navarro VJ

更新日期：2006-03-01 00:00:00

abstract：:STAT6 transcription factor, which has been implicated in commitment to Th2, is known to be activated by IL-4 and IL-13. Accordingly, STAT6 is primarily responsible for the transcriptional effects of IL-4 and IL-13. STAT6-deficient mice are known to have defective IL-4-mediated functions, such as B cell proliferation, ...

journal_title：Clinical and experimental medicine

authors： Kim EG,Shin HJ,Lee CG,Park HY,Kim YK,Park HW,Cho SH,Min KU,Cho ML,Park SH,Lee CW

更新日期：2010-09-01 00:00:00

abstract：:Recently, Th17 cell-associated responses have received growing attention; however, the role of IL-22 (a cytokines also produced by Th17 cells) in the pathogenesis of systemic lupus erythematosus (SLE) has not been widely explored. In this study, we analyze the frequencies of IL-22-positive CD4+/CD8+ T cells in periphe...

journal_title：Clinical and experimental medicine

authors： Qin WZ,Chen LL,Pan HF,Leng RX,Zhai ZM,Wang C,Li RJ,Wang S,Wang HP,Ye DQ

更新日期：2011-12-01 00:00:00

abstract：:Many tumor cells express chemokines and chemokine receptors, and these molecules can affect both tumor progression and anti-tumor immune response. Genetic polymorphisms of some chemokine receptors were found to be closely related to malignant tumors, especially in metastasis process, including breast cancer (BC). Cons...

journal_title：Clinical and experimental medicine

authors： Banin-Hirata BK,Losi-Guembarovski R,Oda JM,de Oliveira CE,Campos CZ,Mazzuco TL,Borelli SD,Ceribelli JR,Watanabe MA

更新日期：2016-05-01 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) has been reported to associate with increased cancer risk in several cancers. However, the role of MIF in breast cancer (BC) susceptibility remains unknown. For the first time, we conducted a case-control study to assess the potential association of three common MIF gene va...

journal_title：Clinical and experimental medicine

authors： Lin S,Wang M,Liu X,Zhu W,Guo Y,Dai Z,Yang P,Tian T,Dai C,Zheng Y,Hu C,Wei L,Dai Z

更新日期：2017-08-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is the prototype autoimmune rheumatic disease. The etiology of this disease is incompletely understood; however, environmental factors and genetic predisposition are involved. Cytokine-mediated immunity plays a crucial role in the pathogenesis of SLE. We investigate the association o...

journal_title：Clinical and experimental medicine

authors： Palafox-Sánchez CA,Oregon-Romero E,Salazar-Camarena DC,Valle YM,Machado-Contreras JR,Cruz A,Orozco-López M,Orozco-Barocio G,Vázquez-Del Mercado M,Muñoz-Valle JF

更新日期：2015-11-01 00:00:00