Permanent oviduct posteriorization after neonatal exposure to the phytoestrogen genistein.

abstract：BACKGROUND:The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. OBJECTIVE:We studied prenatal lead exposure's impact on neurodevelopment using repeated measures of fetal dose as...

journal_title：Environmental health perspectives

authors： Hu H,Téllez-Rojo MM,Bellinger D,Smith D,Ettinger AS,Lamadrid-Figueroa H,Schwartz J,Schnaas L,Mercado-García A,Hernández-Avila M

更新日期：2006-11-01 00:00:00

abstract：:The activities of plants and plant/microbial associations may offer a viable means of accomplishing the in situ remediation of contaminated soils. Two uses of plants for phytoremediation are reported here. In one set of studies, the ability of plants to foster degradative microorganisms was investigated. Results indic...

journal_title：Environmental health perspectives

authors： Shann JR

更新日期：1995-06-01 00:00:00

abstract：:Concentrations of polychlorinated biphenyls (PCBs), hydroxylated metabolites of PCBs (HO-PCBs) and octachlorostyrene (4-HO-HpCS), and pentachlorophenol (PCP) were determined in umbilical cord plasma samples from three different regions of Québec. The regions studied included two coastal areas where exposure to PCBs is...

journal_title：Environmental health perspectives

authors： Sandau CD,Ayotte P,Dewailly E,Duffe J,Norstrom RJ

更新日期：2002-04-01 00:00:00

abstract：:The genetic toxicology databases for chemicals that have been tested extensively are generally composed of inconsistent responses from a diverse set of assays. Consequently, difficulties arise when the data are evaluated for classifying the agent or for assessing the chemical's hazard potential. Several years ago, the...

journal_title：Environmental health perspectives

authors： Brusick D

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Organophosphate flame retardants (PFRs) are becoming popular replacements for the phased-out polybrominated diphenyl ether (PBDE) mixtures, and they are now commonly detected in indoor environments. However, little is known about human exposure to PFRs because they cannot be easily measured in blood or serum...

journal_title：Environmental health perspectives

authors： Hoffman K,Garantziotis S,Birnbaum LS,Stapleton HM

更新日期：2015-02-01 00:00:00

abstract：:The consideration of ethical issues relating to pediatric environmental health is a recent phenomenon. Discussions of biomedical ethics, research on children, and environmental health research have a longer history. In the late 1990s, researchers at the Kennedy Krieger Institute in Baltimore, Maryland, undertook a stu...

journal_title：Environmental health perspectives

authors： Paulson JA

更新日期：2006-10-01 00:00:00

abstract：:Ingestion is an important exposure route for polycyclic aromatic hydrocarbons (PAHs) to enter the human body. Although the formation of hazardous PAH metabolites by human biotransformation enzymes is well documented, nothing is known about the PAH transformation potency of human intestinal microbiota. Using a gastroin...

journal_title：Environmental health perspectives

authors： Van de Wiele T,Vanhaecke L,Boeckaert C,Peru K,Headley J,Verstraete W,Siciliano S

更新日期：2005-01-01 00:00:00

abstract：:Dietary components express a wide range of activities that can affect carcinogenesis. Naturally occurring substances in foods have been shown in laboratory experiments to serve as dietary antimutagens, either as bioantimutagens or as desmutagens. Dietary desmutagens may function as chemical inactivaters, enzymatic ind...

journal_title：Environmental health perspectives

authors： Kohlmeier L,Simonsen N,Mottus K

更新日期：1995-11-01 00:00:00

abstract：:In 1996 the U.S. Congress charged the U.S. Environmental Protection Agency to develop a screening program to test chemicals for their possible estrogenic and other endocrine effects. Shortly thereafter, the Chemical Guidelines Program of the Organisation for Economic Co-operation and Development's (OECD) Environmental...

journal_title：Environmental health perspectives

authors： Colborn T

更新日期：2002-06-01 00:00:00

abstract：:We used real-time monitors and low-volume air samplers to measure the potential human exposure to airborne polycyclic aromatic hydrocarbon (PAH) concentrations during various flight-related and ground-support activities of C-130H aircraft at an Air National Guard base. We used three types of photoelectric aerosol sens...

journal_title：Environmental health perspectives

authors： Childers JW,Witherspoon CL,Smith LB,Pleil JD

更新日期：2000-09-01 00:00:00

abstract：:Cytochrome P450 (CYP) enzymes catalyze the generation of reactive species capable of binding with cellular macromolecules, leading to acute and delayed toxicity. Since individual CYP forms differ markedly in their substrate preferences and regulation, the expression profiles of CYP in various cell types are important ...

journal_title：Environmental health perspectives

authors： Pelkonen O,Raunio H

更新日期：1997-06-01 00:00:00

abstract：:Neurobehavioral toxicology is now established as a core discipline of the environmental health sciences. Despite its recognized scientific prowess, stemming from its deep roots in psychology and neuroscience and its acknowledged successes, it faces additional demands and challenges. The latter, in fact, are a product ...

journal_title：Environmental health perspectives

authors： Weiss B,Elsner J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Although a long latency period of toxicity after exposure to methylmercury (MeHg) is known to exist in humans, few animal studies have addressed this issue. Substantiation of delayed MeHg toxicity in animals would affect the risk evaluation of MeHg. OBJECTIVES:Our goal in this study was to demonstrate the e...

journal_title：Environmental health perspectives

authors： Yoshida M,Shimizu N,Suzuki M,Watanabe C,Satoh M,Mori K,Yasutake A

更新日期：2008-06-01 00:00:00

abstract：:In this article we summarize the results of a series of studies that measured the relative bioavailability (RBA) of lead in a variety of soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice a day for 15 days. Blood samples were col...

journal_title：Environmental health perspectives

authors： Casteel SW,Weis CP,Henningsen GM,Brattin WJ

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The presence of pharmaceuticals in aquatic environments and in drinking water has prompted significant public interest regarding potential adverse ecological effects and risks to human health. OBJECTIVES:The Environmental Health Summit held in North Carolina, 10-11 November 2008, explored the issues associa...

journal_title：Environmental health perspectives

authors： Rodriguez-Mozaz S,Weinberg HS

更新日期：2010-07-01 00:00:00

abstract：:The current Good Manufacturing Practice (cGMP) and effluent emission (use and disposal) regulations of the U.S. Food and Drug Administration (FDA) and manufacturing effluent discharge and emission regulations of the U.S. Environmental Protection Agency (U.S. EPA) require contained manufacture, use, and disposal of pha...

journal_title：Environmental health perspectives

authors： Velagaleti R,Burns PK,Gill M,Prothro J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and endocrine-disrupting chemicals. OBJECTIVES:We used handwipes to estimate exposure to PBDEs in house dust among toddlers and examined sex, age, breast-feeding, race, and parents' education as predictors of serum PBDEs. METHODS:Eight...

journal_title：Environmental health perspectives

authors： Stapleton HM,Eagle S,Sjödin A,Webster TF

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...

journal_title：Environmental health perspectives

authors： Pyko A,Eriksson C,Lind T,Mitkovskaya N,Wallas A,Ögren M,Östenson CG,Pershagen G

更新日期：2017-11-20 00:00:00

abstract：BACKGROUND:Many pesticides in current use have recently been revealed as in vitro androgen receptor (AR) antagonists, but information about their combined effects is lacking. OBJECTIVE:We investigated the combined effects and the competitive AR antagonism of pesticide mixtures. METHODS:We used the MDA-kb2 assay to te...

journal_title：Environmental health perspectives

authors： Orton F,Rosivatz E,Scholze M,Kortenkamp A

更新日期：2012-11-01 00:00:00

abstract：:The 11 September 2001 terrorist attack on New York City's World Trade Center (WTC) caused an unprecedented environmental emergency. The collapse of the towers sent a tremendous cloud of crushed building materials and other pollutants into the air of lower Manhattan. In response to the calamity, federal, state, and cit...

journal_title：Environmental health perspectives

authors： Gavett SH

更新日期：2003-06-01 00:00:00

abstract：:We investigated the metabolic fate of a low dose (25 micro g/kg) of bisphenol A [2,2-bis(4-hydroxy-phenyl)propane] (BPA) injected subcutaneously in CD1 pregnant mice using a tritium-labeled molecule. Analytic methods were developed to allow a radio-chromatographic profiling of BPA residues in excreta and tissues, as w...

journal_title：Environmental health perspectives

authors： Zalko D,Soto AM,Dolo L,Dorio C,Rathahao E,Debrauwer L,Faure R,Cravedi JP

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Cadmium exposure may increase the risk of cardiovascular disease. The only published longitudinal study on cadmium and incident cardiovascular disease was performed in American Indians with relatively high cadmium exposure. OBJECTIVES:Our aim was to examine the association between blood cadmium at baseline ...

journal_title：Environmental health perspectives

authors： Barregard L,Sallsten G,Fagerberg B,Borné Y,Persson M,Hedblad B,Engström G

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Pterygium is a fibrovascular growth of the bulbar conjunctiva and underlying subconjunctival tissue that may cause blindness. The mechanism of pterygium formation is not yet fully understood, but pterygium has some tumorlike features. OBJECTIVES:The objective of this study was to evaluate the association be...

journal_title：Environmental health perspectives

authors： Lin W,Wang SL,Wu HJ,Chang KH,Yeh P,Chen CJ,Guo HR

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes. OBJECTIVE:We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of...

journal_title：Environmental health perspectives

authors： Darrow LA,Stein CR,Steenland K

更新日期：2013-10-01 00:00:00

abstract：:The timing of some key embryological events is given for man, rat, chick, and certain other animals. Such times, however, are approximations, and variations occur among members of the same strain and even among members of the same litter. Some differences in developmental patterns are indicated. ...

journal_title：Environmental health perspectives

authors： Monie IW

更新日期：1976-12-01 00:00:00

abstract：:A set of 53 individuals from a population highly exposed to airborne hexachlorobenzene (HCB) were selected to study the elimination kinetics of this chemical in humans. The volunteers provided blood, 24-hr urine, and feces samples for analysis of HCB and metabolites. The serum HCB concentrations ranged from 2.4 to 1,4...

journal_title：Environmental health perspectives

authors： To-Figueras J,Barrot C,Sala M,Otero R,Silva M,Ozalla MD,Herrero C,Corbella J,Grimalt J,Sunyer J

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Arsenic, cadmium, mercury, and lead are associated with cardiovascular disease in epidemiologic research. These associations may be mediated by direct effects of the metals on blood pressure (BP) elevation. Manganese is associated with cardiovascular dysfunction and hypotension in occupational cohorts. OBJE...

journal_title：Environmental health perspectives

authors： Mordukhovich I,Wright RO,Hu H,Amarasiriwardena C,Baccarelli A,Litonjua A,Sparrow D,Vokonas P,Schwartz J

更新日期：2012-01-01 00:00:00

abstract：:Man-made endocrine-disrupting chemicals (EDCs) present a threat to biodiversity, even in remote areas. To date, numerous wildlife species have been affected by EDCs in the environment, but it is likely that many more species are suffering effects that have not yet been reported. Impaired reproduction, damaged brain fu...

journal_title：Environmental health perspectives

authors： Lyons G

更新日期：2006-04-01 00:00:00

abstract：:The central feature of hemopoiesis is life-long, stable cell renewal. This process is supported by hemopoietic stem cells which, in the steady state, appear to be dormant in cell cycling. The entry into cell cycle of the dormant stem cells may be promoted by such factors as interleukin-1, interleukin-6 (IL-6), and gra...

journal_title：Environmental health perspectives

authors： Ogawa M

更新日期：1989-03-01 00:00:00

abstract：:Systemic lupus erythematosus and systemic scleroderma are autoimmune diseases thought to have an exogenous trigger. This review summarizes relevant case-control and cohort studies that investigated exogenous sex hormones, silica, silicone, solvents, pesticides, mercuric chloride, and hair dyes as putative risk factors...

journal_title：Environmental health perspectives

authors： Mayes MD

更新日期：1999-10-01 00:00:00