Cutaneous angiomas in POEMS syndrome.

abstract：:Sulfur is a time-honored therapeutic agent useful in a variety of dermatologic disorders. Its keratolytic action is due to formation of hydrogen sulfide through a reaction that depends upon direct interaction between sulfur particles and keratinocytes. The smaller the particle size, the greater the degree of such inte...

journal_title：Journal of the American Academy of Dermatology

authors： Lin AN,Reimer RJ,Carter DM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:The association of nonparaneoplastic pemphigus with comorbid hematologic malignancies has yet to be established. OBJECTIVE:To estimate the association between pemphigus and the common types of hematologic malignancies. METHODS:A cross-sectional study was conducted comparing pemphigus patients with age-, se...

journal_title：Journal of the American Academy of Dermatology

authors： Kridin K,Zelber-Sagi S,Comaneshter D,Batat E,Cohen AD

更新日期：2018-06-01 00:00:00

abstract：:We describe a family with the unusual association of Cowden's disease and Bannayan-Riley-Ruvalcaba syndrome. The father has characteristic mucocutaneous features that are palmoplantar keratoses, multiple facial papules, oral papillomatoses, lipomas, and vitiligo with involvement of the thyroid and digestive tract. The...

journal_title：Journal of the American Academy of Dermatology

authors： Perriard J,Saurat JH,Harms M

更新日期：2000-02-01 00:00:00

abstract：:Unlike other mammals that molt hair seasonally, human beings have scalp hair follicles that exhibit an asynchronized pattern of cycling, with the growth and subsequent shedding of each hair being independent of others around it. This mosaic cycling behavior is established early and continues throughout life. We descri...

journal_title：Journal of the American Academy of Dermatology

authors： Thai KE,Sinclair RD

更新日期：2003-11-01 00:00:00

abstract：:Pigmentary demarcation lines are borders of abrupt transition between more deeply pigmented skin and that of lighter pigmentation. Two patients developed these lines on the lower extremities during pregnancy. ...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Meltzer MS,Guill MA,Berger TG,Rodman OG

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Crystalline/chrysalis structures (CS) are white shiny streaks that can only be seen with polarized dermatoscopy. OBJECTIVES:We sought to estimate the prevalence and assess the clinical significance of CS in melanocytic and nonmelanocytic lesions. METHODS:This was a prospective observational study in which ...

journal_title：Journal of the American Academy of Dermatology

authors： Balagula Y,Braun RP,Rabinovitz HS,Dusza SW,Scope A,Liebman TN,Mordente I,Siamas K,Marghoob AA

更新日期：2012-08-01 00:00:00

abstract：:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sha...

journal_title：Journal of the American Academy of Dermatology

authors： Murrell DF,Daniel BS,Joly P,Borradori L,Amagai M,Hashimoto T,Caux F,Marinovic B,Sinha AA,Hertl M,Bernard P,Sirois D,Cianchini G,Fairley JA,Jonkman MF,Pandya AG,Rubenstein D,Zillikens D,Payne AS,Woodley D,Zambruno

更新日期：2012-03-01 00:00:00

abstract：:This prospective study (1977-1980) of cosmetic adverse reactions by eleven dermatologists identified 487 cases of cosmetic-induced dermatitis. Approximately half of the cases were covert in nature. Eight percent were due to allergic contact dermatitis; the face, eye, and upper arm were the most involved sites. Skin ca...

journal_title：Journal of the American Academy of Dermatology

authors： Eiermann HJ,Larsen W,Maibach HI,Taylor JS

更新日期：1982-05-01 00:00:00

abstract：:We report a case of generalized cutaneous chronic graft-versus-host disease in a 17-month-old infant. Topical treatment with the novel ascomycin substance pimecrolimus once daily for 4 weeks led to a near complete clearance of skin lesions. Importantly, this excellent clinical response was obtained without additional ...

journal_title：Journal of the American Academy of Dermatology

authors： Ziemer M,Gruhn B,Thiele JJ,Elsner P

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Primary prevention of skin cancer must start early in life to reduce total life-time sun exposure and severe overexposure in childhood. Childhood is an excellent time to form life-long prevention habits. A school-based curriculum can be an effective prevention strategy. OBJECTIVE:Our purpose was to determin...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Buller MK,Beach B,Ertl G

更新日期：1996-12-01 00:00:00

abstract：:Patients with dark skin can present with morphologic variants, subtle disease presentations, and disease manifestations requiring unique management and therapies. With African Americans, Asians, and Hispanic Americans becoming a significant portion of the population, dermatologists must be able to diagnose and manage ...

journal_title：Journal of the American Academy of Dermatology

authors： Ebede T,Papier A

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:BRAF mutations occur in some melanomas. We hypothesized that BRAF mutation rates may differ in melanomas found in Asian compared to white populations. OBJECTIVE:We performed a metaanalysis of BRAF mutations and their associations with the clinicopathologic characteristics of primary melanoma (PM), with a su...

journal_title：Journal of the American Academy of Dermatology

authors： Kim SY,Kim SN,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The color, architecture, symmetry, and homogeneity (CASH) algorithm for dermoscopy includes a feature not used in prior algorithms, namely, architecture. Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms. OBJECTIVE:We sought ...

journal_title：Journal of the American Academy of Dermatology

authors： Henning JS,Dusza SW,Wang SQ,Marghoob AA,Rabinovitz HS,Polsky D,Kopf AW

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immune evasion. OBJECTIVE:Determine whether aspirin confers longer survival in patients with melanoma. METHODS:A retrospective cohort study of 1522 patients at Indiana University Health who had melanoma diag...

journal_title：Journal of the American Academy of Dermatology

authors： Rachidi S,Wallace K,Li H,Lautenschlaeger T,Li Z

更新日期：2018-05-01 00:00:00

abstract：:Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cu...

journal_title：Journal of the American Academy of Dermatology

authors： Brooke CP,Spiers EM,Omura EF

更新日期：1992-11-01 00:00:00

abstract：:Pruritus is a common symptom in patients with hepatobiliary disease. Numerous treatments have been attempted. We review published therapeutic trials for hepatobiliary pruritus and utilize statistical analysis to evaluate treatment results. Randomized placebo-controlled studies show cholestyramine, rifampin, naloxone, ...

journal_title：Journal of the American Academy of Dermatology

authors： Connolly CS,Kantor GR,Menduke H

更新日期：1995-11-01 00:00:00

abstract：:Sweet's syndrome (SS) occurs most commonly in association with inflammatory or neoplastic disorders. Only rarely has it been associated with immunodeficiency disorders. We describe a child with a T-cell immunodeficiency who had a persistent neutrophilic dermatosis that was histologically and clinically consistent with...

journal_title：Journal of the American Academy of Dermatology

authors： Lipp KE,Shenefelt PD,Nelson RP Jr,Messina JL,Fenske NA

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Ipilimumab is a human antibody that inhibits cytotoxic T-lymphocyte-associated antigen 4, leading to increases in T-cell activation and interleukin 2 secretion and has been approved for the treatment of advanced melanoma. Dermatologic adverse events such as rash, pruritus, and vitiligo have been reported in ...

journal_title：Journal of the American Academy of Dermatology

authors： Minkis K,Garden BC,Wu S,Pulitzer MP,Lacouture ME

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for pa...

journal_title：Journal of the American Academy of Dermatology

authors： Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJ

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:We sought to assess the difference in lesion management between combined examination (naked-eye and dermoscopy) and conventional naked-eye examination in evaluations for melanoma; and to assess the impact on patient treatment of facilities for digital follow-up of diagnostically equivocal lesions. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,de Giorgi V,Chiarugi A,Nardini P,Weinstock MA,Crocetti E,Stante M,Giannotti B

更新日期：2004-05-01 00:00:00

abstract：:The painful orogenital ulcerations of Behçet's disease are among the major symptoms of patients and are often intractable. We assessed the efficacy of granulocyte and monocyte adsorption apheresis therapy in two patients, a 21-year-old man with orogenital ulcerations and a 50-year-old woman with genital ulceration and...

journal_title：Journal of the American Academy of Dermatology

authors： Kanekura T,Gushi A,Iwata M,Fukumaru S,Sakamoto R,Kawahara K,Maruyama I,Kanzaki T

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:The histopathological and clinical overlapping features between condyloma acuminata and bowenoid papulosis can present a diagnostic challenge and we sought to determine if immunochemistry can be helpful in this setting. OBJECTIVE:In this study, we evaluate the specificity and sensitivity of p16 immunohistoc...

journal_title：Journal of the American Academy of Dermatology

authors： Kazlouskaya V,Shustef E,Allam SH,Lal K,Elston D

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Digital dermoscopic image analysis of pigmented skin lesions (PSLs) has become increasingly popular, despite its unclear clinical utility. Unbiased, high-powered studies investigating the efficacy of commercially available systems are limited. OBJECTIVE:To investigate the diagnostic performance of the FotoF...

journal_title：Journal of the American Academy of Dermatology

authors： Del Rosario F,Farahi JM,Drendel J,Buntinx-Krieg T,Caravaglio J,Domozych R,Chapman S,Braunberger T,Dellavalle RP,Norris DA,Fathi R,Alkousakis T

更新日期：2018-05-01 00:00:00

abstract：:The common blue nevus is a benign, localized collection of dermal melanocytes. To date, removal required excisional surgery to eliminate pigment that usually extends into the reticular dermis. We report the successful long-term elimination of common blue nevi on the nasal skin of two patients whose lesions were treate...

journal_title：Journal of the American Academy of Dermatology

authors： Milgraum SS,Cohen ME,Auletta MJ

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The reported prevalence and degrees of Demodex mite infestation in rosacea vary widely. OBJECTIVE:We sought to conduct an evidence-based meta-analysis of the prevalence and degrees of Demodex mite infestation in patients with rosacea. METHODS:Systematic literature review and meta-analysis were conducted. O...

journal_title：Journal of the American Academy of Dermatology

authors： Chang YS,Huang YC

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Nail dystrophies in newborns are rare and are particularly frightening when they appear as masses involving a single digit, suggesting the possibility of a tumor. OBJECTIVE:The aim of this study is to report 3 infants with a congenital pseudoclubbing appearance of a digit and with a reddish discoloration ca...

journal_title：Journal of the American Academy of Dermatology

authors： Piraccini BM,Antonucci A,Rech G,Iorizzo M,Neri I,Patrizi A,Tosti A

更新日期：2005-08-01 00:00:00

abstract：:Four female patients with chromoblastomycosis were completely cured by prolonged topical application of tolerable heat from pocket warmers. The lesions involuted after 2, 3, and 6 months, respectively, in three patients who faithfully followed our strict treatment schedule, in contrast to the fourth patient who perfor...

journal_title：Journal of the American Academy of Dermatology

authors： Tagami H,Ginoza M,Imaizumi S,Urano-Suehisa S

更新日期：1984-04-01 00:00:00

abstract：:Many patients with lipoprotein disorders are at increased risk for the development of premature atherosclerosis and, less commonly, other disorders that cause systemic morbidity. In some of these patients, xanthomas also develop and provide cutaneous markers for the lipoprotein disorder. As advances in molecular biolo...

journal_title：Journal of the American Academy of Dermatology

authors： Cruz PD Jr,East C,Bergstresser PR

更新日期：1988-07-01 00:00:00