Abstract:
Introduction:Introduction: in Mexico the main problem in public health is obesity and other diseases that are associated whit this condition, including oral health. Objective: to evaluate the effect of metformin treatment in patients with class I obese on the activity of metalloproteinases present in periodontium with chronic periodontitis. Methods: a clinical study was conducted in 68 patients with class I obesity and periodontal disease. They were divided into 4 groups. 2 of them, in addition to the periodontal treatment, were administered metformin 850 mg per day for six weeks; 2 samples were taken per patient of periodontal tissue before and after each treatment, body mass index, plaque index and inflammation were measured. Acrylamide gel zymography was used to measure the activity of metalloproteinases in the sample of tissue collected. The data obtained were analyzed by descriptive statistics, student t for related samples and one-way ANOVA was performed considering p < 0.01 as statistically significant. Results: in the group of patients who were administered metformin at the end of the treatment, there was a decrease in the body mass index, the degree of inflammation and lower metalloproteinase activity, compared with the control group (65% vs 25%; < 0.01). Conclusions: treatment with metformin in patients with obesity class I and periodontal disease decreases BMI, improves the symptoms of chronic periodontitis and decreases the activity of metalloproteinases 1, 3, 8, V present in periodontium of these patients. Introducción:Introducción: el principal problema de salud pública en México es la obesidad y sus enfermedades asociadas, incluyendo las bucales. Objetivo: evaluar el efecto del tratamiento con metformina en pacientes obesos de clase I sobre la actividad de las metaloproteinasas presentes en el periodonto con periodontitis crónica. Métodos: se realizó un estudio clínico con 68 pacientes mujeres con obesidad de clase I y enfermedad periodontal. Se dividieron en 4 grupos; a 2 de ellos, además del tratamiento periodontal, se les administro metformina de 850 mg al día durante seis semanas. Se tomaron 2 muestras por paciente de tejido periodontal antes y después de cada tratamiento y se midió el índice de masa corporal (IMC), el índice de placa dentobacteriana y de inflamación. Mediante zimografía en gel de acrilamida se midió la actividad de las metaloproteinasas en la muestra de tejido recolectada. Los datos obtenidos fueron analizados mediante estadística descriptiva t de student para muestras relacionadas y se realizó ANOVA de una vía considerando p < 0,01 como estadísticamente significativa. Resultados: en el grupo de pacientes a las que se les administro metformina al final del tratamiento se observó una disminución del índice de masa corporal, del grado de inflamación y menor actividad de metaloproteinasas respecto al grupo control (65% frente a 25%; p < 0,01). Conclusiones: el tratamiento con metformina en pacientes con obesidad de clase I y enfermedad periodontal disminuye el IMC, mejora los síntomas de la periodontitis crónica y disminuye la actividad de las metaloproteinasas 1, 3, 8 y V presentes en el periodonto de estos pacientes.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Zúñiga Curz CA,Calzada Mendoza CC,Miranda Mondragón ID,Bustamante Bacame A,Portilla Robertson J,Ocharán Hernández Edoi
10.20960/nh.02602subject
Has Abstractpub_date
2019-10-17 00:00:00pages
1095-1100issue
5eissn
0212-1611issn
1699-5198journal_volume
36pub_type
杂志文章abstract::The aim of the present study was to describe the clinical- nutritional evolution of older women submitted to Roux-en-Y gastric bypass surgery. A concurrent, retrospective study was conducted involving a sample of 16 older women with morbid obesity submitted to Rouxen- Y gastric bypass surgery between 1997 and 2010. We...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.3.8112
更新日期:2014-10-03 00:00:00
abstract:INTRODUCTION:Obese adolescents have higher cardiovascular risk (CVR). Intima-media thickness (IMT) detects early arterial vascular compromise. OBJECTIVE:To evaluate whether obese adolescents have higher vascular compromise measured by IMT than nonobese adolescents, and if this is greater in those with metabolic syndro...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112012000100023
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Anemia is one of the most important nutritional deficiencies affecting various social and socioeconomic strata. It is more common in developing countries, with children and adolescents being at a significantly higher risk for the condition. OBJECTIVE:To perform a literature review on iron deficiency anemi...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2014.29.6.7245
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Amyotrophic Lateral Sclerosis (ALS) is a degenerative disorder that affects the pyramidal tract, producing progressive motor dysfunctions leading to paralysis. These patients can present with dysphagia, requiring nutritional support with a nasogastric tube or Percutaneous Endoscopic Gastrostomy (PEG). PEG is...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.30.6.7808
更新日期:2014-12-01 00:00:00
abstract::Tube feeding is a widely used medical treatment for providing nutrition to terminally ill patients. Long term nutritional support in these patients or patients with irreversible neurological deterioration create a host of ethical and legal conflicts with difficult solutions. This work looks at the cultural and ethical...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract:INTRODUCTION:Approximately two thirds of cancer patients at advanced stages of the disease suffer from anorexia. Defined as the loss of the desire to eat, anorexia lower the energy intake which further exacerbates a progressive deterioration of the patient nutritional status. Malnutrition has a large impact on morbidit...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.1590/S0212-16112011000400003
更新日期:2011-07-01 00:00:00
abstract:Introduction:Objective: iron deficiency anemia is associated with adverse results for health and it is highly prevalent worldwide. The current study evaluated the prevalence and the sociodemographic factors associated with iron deficiency anemia in a sample of Colombian pregnant women. Materials and methods: the second...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1895
更新日期:2019-03-07 00:00:00
abstract::At our hospital, there is an At-Home Enteral Nutrition programme (NED in its Spanish acronym) with participation of the Clinical Nutrition Unit and the Pharmacy Service. The products and all necessary material are dispensed directly to the patient's home and nutritional follow-up is carried out. As a lack of informati...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:The Metabolic Syndrome is one of the first health problems in the public health of the century. It's consider that the beginning of the syndrome is determined by numerous factors that developed two main metabolic disturbances: the insulin resistance and the central obesity. This relationship is concentrati...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2012.27.4.5825
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Malnutrition among inpatients is highly prevalent, and has a negative impact on their clinical outcome. The Working Group for the Study of Malnutrition in Hospitals in Catalonia was created to generate consensus guidelines for the prevention and/or treatment of malnutrition in hospitals in Catalonia, Spain. ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,多中心研究
doi:10.1590/S0212-16112012000200018
更新日期:2012-03-01 00:00:00
abstract:Introduction:Objective: to evaluate a healthy food program for teachers and their educational transfer through an action plan for 3rd to 5th primary students, to improve their food habits and culinary skills. Methodology: a four months quasi-experimental prospective study was carried out, with qualitative measurements ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.2190
更新日期:2019-04-10 00:00:00
abstract:OBJECTIVE:we analyzed the rural-urban differences of the nutritional status by residence (DRU) of the Basque male population during the Industrial Revolution. METHODS:We used data from the military recruitment of 1876-1936 (cohorts born in 1856-1915). We analyzed the heights of 12,747 conscripts in six municipalities ...
journal_title:Nutricion hospitalaria
pub_type: 历史文章,杂志文章
doi:10.20960/nh.2084
更新日期:2018-06-04 00:00:00
abstract:BACKGROUND:The intragastric balloon is widely used for weight reduction in obese patients, but results are variable. We describe our results enhancing the importance of a Multidisciplinary Team (MT) taking part in the treatment. METHODS:A retrospective review was done concerning a total of 119 balloons , placed in 116...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract:RATIONALE:The ELAN Ecuadorian Study of Hospital Malnutrition returned a malnutrition rate of 37.1% in public hospitals of Ecuador [Gallegos Espinosa S, Nicolalde Cifuentes M, Santana Porbén S; para el Grupo Ecuatoriano de Estudio de la Desnutrición Hospitalaria. State of malnutrition in hospitals of Ecuador. Nutr Hosp ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.1.8178
更新日期:2014-10-03 00:00:00
abstract:INTRODUCTION:A sufficient intake of calcium enables correct bone mineralization. The bioavailability of calcium in water is similar to that in milk. OBJECTIVE:To determine the concentration of calcium in public drinking water and bottled mineral water. METHODS:We used ion chromatography to analyse the calcium concent...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.30.1.7491
更新日期:2014-07-01 00:00:00
abstract::As part of the nutritional survey of the Canary Islands (ENCA-1998), the concentrations in serum of Na, K, Ca and P were determined in 395 individuals representing the population of the Canary Islands. The concentrations were found to be within the reference intervals described for the healthy population. Differences ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract:Introduction:The infl uence of exercise in trained subjects has beneficial effects in the physical fi tness and body composition; however, detraining has an unfavorable effect in all of them. Objective:The current study was designed to ascertain the infl uence of a six week-detraining period on body composition in bot...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.618
更新日期:2017-06-05 00:00:00
abstract::Obesity and breast cancer are two very frequent pathologies in the world today, which have a strong impact on society. Various research studies have tried linking the two. For this purpose, data was collected from the medical histories of 524 women who had been diagnosed and treated for breast cancer from January 2009...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000400033
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION:Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) coinfection may cause nutrient deficiency and affect the nutritional status.Objetive: To assess nutritional status, and energy and macronutrient intake in HCV/HIV coinfected patients. METHODS:Cross-sectional study on HIV/HCV-coinfected patient...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.576
更新日期:2016-10-18 00:00:00
abstract::Resection of long segments of the small bowel may cause variable degrees of malabsorption. Therefore, the results of the resection will depend on the length and location of the resected segment, and on the age of the patient and the underlying disease that motivated the resection. The implementation of Nutritional Sup...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To determine possible associations between the risk of breast cancer in Brazilian women and demographic, social and economical variables, and past dietary intake. METHODS:A case-control study was conducted in Joinville, Santa Catarina, Brazil, between june and november 2003 involving a group of 33 women rece...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,多中心研究
doi:
更新日期:2007-09-01 00:00:00
abstract::The literature contains a large number of published articles indicating a strong relationship between obesity and morbidity-mortality due to different cause. There are also various short- to medium-term studies demonstrating the benefits of a moderate weight loss on the control of obesity-related risk factors. Nonethe...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2002-02-01 00:00:00
abstract:INTRODUCTION:apart from the known effects of vitamin D on phospho-calcium homeostasis, in recent years there is great interest in its extrabone effects. OBJECTIVES:to know the concentration of 25-hydroxyvitamin D (25[OH] D) in newly diagnosed patients of cancer and to verify if there are differences between the differ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1675
更新日期:2018-04-05 00:00:00
abstract:Introduction:Aim and background: the incidence of obesity has increased among children, and obesity has been considered an independent risk factor for chronic kidney disease. We aimed to determine the degree of kidney function impairment by evaluating urine neutrophil gelatinase-associated lipocalin (NGAL) and kidney i...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02651
更新日期:2020-07-13 00:00:00
abstract:INTRODUCTION:Chile is a country that reaches the highest levels of overweight and obesity worldwide (66.7% of the Chilean population), with a group of college students tending to swell these numbers considered nutritionally vulnerable group. OBJECTIVE:To associate the consumption of fruits with nutritional status of C...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.5.8617
更新日期:2015-05-01 00:00:00
abstract:Introduction:A large evidence-based reports a J-shaped association among moderate alcohol consumption and cardiovascular health. Low-moderate alcohol intake has been related to lower all-cause mortality (20%) and ischemic heart events (40%) compared to abstainers. The dose that is allegedly beneficial varies between 10...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.02811
更新日期:2019-08-27 00:00:00
abstract::Los datos del estudio PREDYCES® nos revelaron que en España la desnutrición relacionada con la enfermedad (DRE) afecta a uno de cada cuatro pacientes hospitalizados. Esta cifra aumenta hasta el 36,8% en los pacientes hematológicos. Se calcula que un 20% de los pacientes oncológicos muere por complicaciones relacionada...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.180
更新日期:2016-06-03 00:00:00
abstract:INTRODUCTION:The Food Neophobia Scale (FNS), originally developed in English, has been widely used in different studies to assess the individual's willingness to try new foods. However, a process of translation and cultural adaptation is required to enable the use of FNS in other countries. OBJECTIVE:to translate and ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.2.9108
更新日期:2015-08-01 00:00:00
abstract::We present a case of a 46-year-old woman who is hospitalized in March of 1997 for a picture of severe mixed malnutrition. We describe the clinical history since the diagnosis of an endometrium carcinoma in 1995, treated with radiation therapy, with the aim of determining the etiology of the severe malnutrition picture...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:The maintenance of healthy lifestyles is of great importance to prevent pregnancy-related diseases at early stages. For this reason, the knowledge of the overall wellbeing of women at childbearing-age is necessary to provide appropriate advice to maintain or improve the nutritional status. The aim of this re...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.29.2.7082
更新日期:2014-02-01 00:00:00