Abstract：
:UV light leads to release of different secretory factors from irradiated cells of which some of them have been characterized. We have reported earlier that cells exposed to the supernatant medium from irradiated cells were resistant to killing by some genotoxic agents. In this study, we present our finding that demonstrates DNA damage induced by UV or H(2)O(2) is lowered on prior exposure to the UV released factors (UVRF). Production of ROS in cells and lipid peroxidation was also lowered. It was found that treatment of unexposed cells with UVRF present in the supernatant medium altered the antioxidant defense activity in cells. Significant was the increase in catalase (CAT) and Cu-Zn superoxide dismutase (SOD) activity, whereas glutathione peroxidase (GPx) and reduced glutathione (GSH) levels remained unaffected. Cells exposed to UVRF prior to UV or H(2)O(2) treatment also experienced such upregulation; however, the remarkable increase in the GPx activity exhibited by these cells was not observed in cells exposed to H(2)O(2) or UV alone. It appears that exposure to UVRF tinkered with antioxidant defense in cells to facilitate its proliferation upon assault by an agent that can produce oxidative damage.
journal_name
Photochem Photobioljournal_title
Photochemistry and photobiologyauthors
Ghosh R,Guha D,Bhowmik Sdoi
10.1111/j.1751-1097.2012.01105.xsubject
Has Abstractpub_date
2012-05-01 00:00:00pages
708-16issue
3eissn
0031-8655issn
1751-1097journal_volume
88pub_type
杂志文章abstract：:Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectanc...
journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.1991.tb08470.x
更新日期：1991-01-01 00:00:00
abstract：:It has previously been demonstrated that chronic low-dose solar-simulated UV radiation could induce both local and systemic immunosuppression as well as tolerance to a topically applied hapten. In this study, we have used a chronic low-dose UV-irradiation protocol to investigate the effects of UVA on the skin immune s...
journal_title：Photochemistry and photobiology
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doi：10.1111/j.1751-1097.1996.tb01863.x
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.1991.tb03657.x
更新日期：1991-04-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章,评审
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更新日期：2019-01-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 评论,杂志文章
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更新日期：2019-01-01 00:00:00
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更新日期：2020-11-01 00:00:00
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doi：
更新日期：1999-11-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.1985.tb01642.x
更新日期：1985-01-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.2008.00367.x
更新日期：2008-11-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.1991.tb02033.x
更新日期：1991-09-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.2011.01023.x
更新日期：2012-01-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.2010.00819.x
更新日期：2011-01-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1562/2004-03-11-RA-109
更新日期：2004-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：1992-01-01 00:00:00
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journal_title：Photochemistry and photobiology
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更新日期：2003-10-01 00:00:00
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doi：10.1111/php.12505
更新日期：2015-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-09-01 00:00:00
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journal_title：Photochemistry and photobiology
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doi：
更新日期：1998-10-01 00:00:00
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journal_title：Photochemistry and photobiology
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更新日期：2012-03-01 00:00:00
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journal_title：Photochemistry and photobiology
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更新日期：2004-05-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
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更新日期：1995-05-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/php.12838
更新日期：2018-03-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.1995.tb08713.x
更新日期：1995-10-01 00:00:00
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journal_title：Photochemistry and photobiology
pub_type： 杂志文章
doi：10.1111/j.1751-1097.2011.01022.x
更新日期：2012-01-01 00:00:00
